Dermatologic Surgery最新文献_第5页

Immunosuppression as an Independent Risk Factor for Poor Outcomes in Cutaneous Squamous Cell Carcinoma: A Prospective Study. 免疫抑制是皮肤鳞状细胞癌预后不良的独立危险因素：一项前瞻性研究。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004680

Amanda Rosenthal, Geena Conde, Joseph Dodson, Margit Juhasz, Nima Gharavi

{"title":"Immunosuppression as an Independent Risk Factor for Poor Outcomes in Cutaneous Squamous Cell Carcinoma: A Prospective Study.","authors":"Amanda Rosenthal, Geena Conde, Joseph Dodson, Margit Juhasz, Nima Gharavi","doi":"10.1097/DSS.0000000000004680","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004680","url":null,"abstract":"Background: The impact of immunosuppression on poor outcomes in cutaneous squamous cell carcinoma (cSCC) remains unclear.Objective: To quantify the effect of immunosuppression on poor outcomes in cSCC and compare its prognostic value to currently accepted high-risk features.Methods: Single-center, prospective study conducted between January 1, 2014, and December 31, 2021. Outcomes of interest included recurrence, nodal involvement, metastasis, and cSCC-specific mortality. Multivariate logistic regression was performed to identify independent predictors of the grouped dependent variable: poor outcomes.Results: One thousand four hundred unique cases of cSCC were identified among 929 patients, of which 156 (16.8%) were immunosuppressed. Immunosuppressed patients were more likely to develop Brigham and Women's Hospital T2b/T3 tumors (p < .0001) and experience poor outcomes (p < .0001). Immunosuppression was independently associated with poor outcomes (AOR: 3.44; p = .011), when controlling for differentiation, depth of invasion, perineural invasion (PNI), and size. Immunosuppression outperformed clinical size ≥2 cm (AOR:2.45; p = .021), PNI (AOR:2.81; p = .54), and deep invasion (AOR:6.61; p = .07) in predicting poor outcomes.Conclusion: The authors demonstrate that immunosuppression is a significant independent predictor of poor outcomes in cSCC and outperforms currently accepted high-risk features. This analysis suggests that cSCC in immunosuppressed patients may have a distinct, more aggressive tumor biology that is not fully captured by traditional staging systems.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Finessing Second Intent Healing: Using Suspension Sutures. 第二意图治疗：使用悬浮缝合线。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004684

Neera R Nathan, Jeffrey B Tiger, Olushola Jimoh-George, Laura M Sowerby

引用次数: 0

Clinical and Histologic Correlation of Dermal Microwave Energy for Axillary Bromhidrosis. 腋下腋臭皮肤微波能量的临床与组织学相关性研究。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004677

Jordan V Wang, Neil Jairath, Roy G Geronemus

引用次数: 0

A Novel Subclassification of Type 2 Dermal Insertion Structures. 2型真皮插入结构的新亚分类。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004661

Kyu-Ho Yi, Jovian Wan, Song Eun Yoon, Benrita Jitaree, Hee-Jin Kim

{"title":"A Novel Subclassification of Type 2 Dermal Insertion Structures.","authors":"Kyu-Ho Yi, Jovian Wan, Song Eun Yoon, Benrita Jitaree, Hee-Jin Kim","doi":"10.1097/DSS.0000000000004661","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004661","url":null,"abstract":"Background: Current anatomical classifications inadequately represent dermal insertion structures critical to facial movement, support, and aesthetic outcomes. Particularly, Type 2 structures-defined by direct connections to the dermis-lack precise subclassification.Objective: To introduce and validate a novel subclassification system for Type 2 dermal insertion structures based on their origin, composition, and clinical relevance in aesthetic and reconstructive procedures.Materials and methods: Detailed cadaveric dissections (n = 20 hemifaces) were conducted to evaluate the microarchitecture and insertion patterns of muscles and ligaments associated with dermal anchoring. Structures were categorized into 4 subtypes based on anatomical origin and fiber composition.Results: Four distinct subtypes were identified: Type 2a (muscle fibers directly inserting into dermis), Type 2b (muscle-collagen transitions), Type 2c (true ligaments anchoring dermis to bone or fascia), and Type 2d (retaining ligaments from intermediate layers). This classification enhances anatomical precision, improves procedural safety, and guides intervention strategies in injectable, thread-based, and surgical techniques.Conclusion: The proposed Type 2 subclassification provides a clinically meaningful framework for understanding dermal insertions. It supports personalized aesthetic planning and dynamic facial rejuvenation by integrating structural anatomy with procedural targeting.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hair Transplantation: State of the Art. 头发移植：最新技术。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004675

Dawn Queen, Marc R Avram

{"title":"Hair Transplantation: State of the Art.","authors":"Dawn Queen, Marc R Avram","doi":"10.1097/DSS.0000000000004675","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004675","url":null,"abstract":"Background: Hair transplantation is a minimally invasive procedure for treating hair loss in men and women, based on the principle of donor dominance, where transplanted hair retains its genetic characteristics in new locations. It is primarily used for androgenetic alopecia but also can be used in end-stage cicatricial alopecia and as a corrective procedure post-trauma or surgery.Objective: This review provides an overview of the current status of hair transplant surgery in the last 5 years, as well as a guide for patient selection, technical considerations, instrumentation, and postoperative care.Methods/materials: A review was conducted of the PubMed database between 2019 and 2024 and included 1,030 study abstracts.Results: Follicular unit extraction and (linear strip) excision are both state of the art methods for hair transplantation. New devices have been developed for extraction and insertion of follicular units. Thoughtful hairline design and concurrent medical management have improved aesthetic results.Conclusion: Hair transplantation has experienced a surge in popularity due to advances in devices, techniques, and medical therapies to maintain hair density, leading to long-lasting, natural results and high patient satisfaction. Future directions include improvements in instrumentation, artificial intelligence, hair follicle cloning, and enhanced adjuvant medical management.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superficial Migration of the Facial Artery After Repeated Intralesional Corticosteroid Injections. 反复病灶内注射皮质类固醇后面部动脉的浅表迁移。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004679

Mercedes Hennessey, Sam Nguyen, Gloria DuMaine, James V Twede

引用次数: 0

The History of Non-Laser Energy-Based Devices in Dermatology. 皮肤病学中非激光能量装置的历史。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004705

Susruthi Rajanala, Michael S Kaminer, Thomas E Rohrer

{"title":"The History of Non-Laser Energy-Based Devices in Dermatology.","authors":"Susruthi Rajanala, Michael S Kaminer, Thomas E Rohrer","doi":"10.1097/DSS.0000000000004705","DOIUrl":"10.1097/DSS.0000000000004705","url":null,"abstract":"Background: From the initial development of radiofrequency devices to new technologies such as micro-coring, there has been tremendous growth of nonlaser energy-based devices in dermatology over the past few decades.Objective: To review the origins and development of energy-based devices in dermatology and dermatologic surgery.Materials and methods: A literature search was conducted on PubMed from inception to February 1, 2025 to identify critical publications on energy-based devices within dermatology.Results: Since the initial research surrounding radiofrequency-based surgical tools in the 1990s, numerous dermatologists have pioneered the development of energy-based devices to target skin laxity and texture, enhance body contouring, and improve muscle tone. The rise of these energy-based devices has allowed for minimally invasive treatments to address patients' aesthetic concerns with less pain and downtime.Conclusion: Dermatologists have played a critical role in the advancement behind the rise of energy-based devices for a variety of aesthetic indications. Dermatologic Surgery has published many of the landmark studies behind these devices and continues to be at the forefront of innovation for further research and clinical trials.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":"575-582"},"PeriodicalIF":2.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Earlobe Rejuvenation Using Poly-L-Lactic Acid. 使用聚l -乳酸恢复耳垂。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-12 DOI: 10.1097/DSS.0000000000004683

Doris Hexsel, Clarissa Prieto Herman Reinehr, Ana Carolina Krum Dos Santos, Nathalia Hoffmann Guarda Aguzzoli

引用次数: 0

Beyond Repigmentation-A Prospective Study of Patients With Stable Vitiligo Treated With Suction Blister Epidermal Grafting Plus Phototherapy. 超越色素沉着-吸疱表皮移植加光疗治疗稳定型白癜风患者的前瞻性研究。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-07 DOI: 10.1097/DSS.0000000000004678

Lu Yang, Yuehua Liu, Tao Wang

{"title":"Beyond Repigmentation-A Prospective Study of Patients With Stable Vitiligo Treated With Suction Blister Epidermal Grafting Plus Phototherapy.","authors":"Lu Yang, Yuehua Liu, Tao Wang","doi":"10.1097/DSS.0000000000004678","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004678","url":null,"abstract":"Background: Vitiligo is a common skin disorder that greatly impacts patients' appearance. The effects of grafting surgery combined with phototherapy on repigmentation and quality of life in patients with vitiligo remain underexplored.Objective: To evaluate the effect of suction blister epidermal grafting (SBEG) combined with phototherapy on repigmentation and quality of life in patients with stable vitiligo.Materials and methods: This prospective study included 42 skin lesions from 23 patients with stable vitiligo who underwent SBEG followed by postoperative phototherapy. Repigmentation rate, Dermatology Life Quality Index (DLQI), and Vitiligo-specific Quality-of-life Instrument (VitiQoL) scores were assessed at 3 and 6 months postoperation.Results: The mean repigmentation rates at 3 and 6 months were 63.35% (±4.90) and 70.23% (±4.27), respectively. Lesions covered with terminal hair exhibited lower repigmentation rates compared to those without. Quality of life improved significantly, with DLQI scores decreasing from 7.37 to 4.06 at 6 months postsurgery (p = .0213). No significant correlation was found between DLQI or VitiQoL improvement rates and repigmentation rates.Conclusion: SBEG combined with postoperative phototherapy effectively promotes repigmentation in stable vitiligo, particularly in areas without terminal hair. The procedure also enhances patient quality of life, although the relationship between repigmentation and quality of life requires further investigation.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cutaneous Fibrofolliculomas and Trichodiscomas in Birt-Hogg-Dubé Syndrome: A Review of Therapeutic Surgical Strategies. birt - hogg - dub<s:1>综合征的皮肤纤维毛囊瘤和毛癣：手术治疗策略的综述。

IF 2.5 3区医学

Dermatologic Surgery Pub Date : 2025-05-07 DOI: 10.1097/DSS.0000000000004671

William Fostier, Neil Rajan

{"title":"Cutaneous Fibrofolliculomas and Trichodiscomas in Birt-Hogg-Dubé Syndrome: A Review of Therapeutic Surgical Strategies.","authors":"William Fostier, Neil Rajan","doi":"10.1097/DSS.0000000000004671","DOIUrl":"https://doi.org/10.1097/DSS.0000000000004671","url":null,"abstract":"Background: Birt-Hogg-Dubé syndrome (BHD) is an autosomal dominant genodermatosis characterized by multiple cutaneous fibrofolliculomas and trichodiscomas, lung cysts, and renal cell carcinoma.Objective: To review the surgical strategies used to manage fibrofolliculomas and trichodiscomas, developing recommendations for surgical treatment.Methods: A literature search was conducted to review cases of BHD associated fibrofolliculomas and trichodiscomas and the role of cryosurgery, curettage, dermabrasion, electrosurgery, lasers, and surgical excision as therapies.Results: A total of 17 articles were included. Randomized controlled trials were absent, and isolated reports or small series reporting on the use of cryosurgery, dermabrasion, lasers, electrosurgery with and without curettage, and surgical excision were found. Electrosurgery demonstrated good tolerability and limited recurrence 24 to 72 months postprocedure. Laser treatments of BHD tumors included ablative Erbium: YAG and unfractionated/fractionated carbon dioxide (CO2) lasers. Recurrence varied from 3 to 48 months. Combination approaches using both CO2 laser and surgical debulking have also demonstrated benefit. One study combined topical rapamycin with nonablative fractional laser therapy.Conclusion: Each surgical modality has an associated benefit and risk profile. Consistent with inherited skin tumor syndromes, relapse and recurrence postprocedure is common. Development of a novel topical therapy remains attractive and requires mechanistic understanding of the tumorigenesis of BHD skin tumors.","PeriodicalId":11289,"journal":{"name":"Dermatologic Surgery","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0