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Magnetic Resonance Imaging for Distinguishing Perianal Hidradenitis Suppurativa from Fistulizing Crohn Disease. MRI鉴别化脓性肛周汗腺炎与化脓性克罗恩病。
IF 2.7 3区 医学
Dermatology Pub Date : 2025-07-25 DOI: 10.1159/000547570
Mika Yamanaka-Takaichi, Edward V Loftus, David Anthony Wetter, Afsaneh Alavi, Eric C Ehman, Mariana Yalon, Anna B Grimaldo, Austin Todd, Hamid R Tizhoosh, Eric J Dozois
{"title":"Magnetic Resonance Imaging for Distinguishing Perianal Hidradenitis Suppurativa from Fistulizing Crohn Disease.","authors":"Mika Yamanaka-Takaichi, Edward V Loftus, David Anthony Wetter, Afsaneh Alavi, Eric C Ehman, Mariana Yalon, Anna B Grimaldo, Austin Todd, Hamid R Tizhoosh, Eric J Dozois","doi":"10.1159/000547570","DOIUrl":"10.1159/000547570","url":null,"abstract":"<p><strong>Introduction: </strong>Both hidradenitis suppurativa (HS) and Crohn disease (CD) are characterized by suppuration and granulomatous inflammation, which may result in formation of tunnels, sinus tracts, or fistulas. We sought to determine the differences in characteristics of fistulizing perianal CD vs. perianal HS on magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>This retrospective cohort study included patients diagnosed with CD, HS, or both diseases who underwent medical examination at the Mayo Clinic between January 1, 1998, and July 31, 2021. We further selected patients who had documented perianal lesions and underwent pelvic MRI. Two abdominal radiologists blinded to clinical diagnosis reviewed the MR images for the presence or absence of 10 characteristics. For characteristics that differed significantly between patients with CD and HS, odds ratios were calculated. A radiomics-based MRI scoring system was constructed according to the odds ratios and was validated.</p><p><strong>Results: </strong>On MRI, significantly more patients in the HS group (n = 49) than the CD group (n = 74) had subcutaneous tunnels (35% vs. 4%; p < 0.001), soft-tissue inflammation of subcutaneous tissue and skin (35% vs. 5%; p < 0.001), and inguinal lymphadenopathy (65% vs. 45%; p = 0.02). Significantly more patients in the CD group than the HS group had transsphincteric fistula (64% vs. 35%; p = 0.002), intersphincteric fistula (58% vs. 29%; p = 0.001), mesorectal lymphadenopathy (26% vs. 4%; p = 0.002), and rectal inflammation (32% vs. 12%; p = 0.01). The proposed MRI scoring system for distinguishing HS from CD had a sensitivity of 0.77, specificity of 0.80, and area under the curve of 0.84.</p><p><strong>Conclusion: </strong>MRI may be a valuable tool in distinguishing perianal draining tunnels in HS from fistulizing perianal CD. The MRI scoring system we created could help in the clinical decision-making process. Combining MRI with other investigational and clinical findings may improve diagnostic accuracy for these challenging perianal diseases.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-10"},"PeriodicalIF":2.7,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Martian Dermatology: A Narrative Review of Dermatoses for Future Explorers. 火星皮肤病学:对未来探索者皮肤病的叙述回顾。
IF 2.7 3区 医学
Dermatology Pub Date : 2025-07-14 DOI: 10.1159/000547408
Ryan Scheinkman, Rahul Aggarwal, Eran Gwillim, Fulvia Verde, Keyvan Nouri
{"title":"Martian Dermatology: A Narrative Review of Dermatoses for Future Explorers.","authors":"Ryan Scheinkman, Rahul Aggarwal, Eran Gwillim, Fulvia Verde, Keyvan Nouri","doi":"10.1159/000547408","DOIUrl":"10.1159/000547408","url":null,"abstract":"<p><strong>Background: </strong>The complex interplay of the Martian environment, equipment, and difficulties of delivering care presents unique challenges for dermatology.</p><p><strong>Summary: </strong>In this review, we sought to provide an overview of dermatological challenges associated with future human exploration of the surface of Mars and provide information on preventative strategies and treatment methods. Sources relevant to Martian dermatology were collated from a PubMed and Google Scholar relevant to dermatological conditions associated with Martian exploration. Dermatoses from equipment and environmental factors (e.g., radiation, regolith, decompression from low pressure) were reviewed for pathology, treatment, and prevention.</p><p><strong>Key messages: </strong>Dermatologists can help inform human factors engineering solutions for mission design (e.g., space suit considerations for skin), provide preventative guidance, inform diagnosis and treatment protocols, and provide remote consoling for patients through teledermatology as skin health concerns arise.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-9"},"PeriodicalIF":2.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hidradenitis Suppurativa Prevalence in Santiago, Chile. 智利圣地亚哥化脓性汗腺炎流行情况。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000538423
Francisco Reyes-Baraona, Carlos Matas, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec
{"title":"Hidradenitis Suppurativa Prevalence in Santiago, Chile.","authors":"Francisco Reyes-Baraona, Carlos Matas, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec","doi":"10.1159/000538423","DOIUrl":"10.1159/000538423","url":null,"abstract":"<p><strong>Background: </strong>The worldwide prevalence of hidradenitis suppurativa (HS) still remains unknown. In Latin America, there are scarce data regarding the prevalence of HS and in Chile, we do not have information about it. The aim of this study was to estimate the prevalence of HS in Santiago, Chile.</p><p><strong>Methods: </strong>This study is part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative. It was a multicenter center study in secondary care in Santiago, Chile. The inclusion criteria were apparently healthy adults accompanying a patient to the health center that were approached in the waiting room of internal medicine or pediatrics departments. A previously validated screening questionnaire for HS was used. Screen-positive and randomly selected screen-negative participants were clinically examined.</p><p><strong>Results: </strong>500 participants were included. The prevalence of HS in the sample was 2.4% (12/500; 95% CI: 1.4%-4.1%). In the HS group, all were female (100%; p = 0.019), with a median age of 35.5 years (p = 0.089) and 25% were smokers (p = 1). Body mass index (BMI) of patients with HS was significant higher than non-HS patients (30.9 kg/m2 and 28.1 kg/m2, respectively; p = 0.028). Axilla and groin were the predominant sites of affection (58.3% each one). 75% of HS patients were classified as Hurley stage I and 25% as Hurley stage II.</p><p><strong>Conclusion: </strong>The estimated prevalence of HS in Santiago of Chile was 2.4%, which is high compared to other previous reports worldwide but similar to other countries participating in the GHiSA initiative. In our study, we only had female patients with HS, suggesting a clear predominance of women suffering HS in Chile. A high BMI appears to be a risk factor for HS in our population. The screening questionnaire for HS is a suitable tool for population surveys.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-5"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hidradenitis Suppurativa in Bucharest, Romania. 罗马尼亚布加勒斯特化脓性汗腺炎的流行情况。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000540423
Elena-Daniela Serban, Maria-Magdalena Constantin, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec
{"title":"Prevalence of Hidradenitis Suppurativa in Bucharest, Romania.","authors":"Elena-Daniela Serban, Maria-Magdalena Constantin, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec","doi":"10.1159/000540423","DOIUrl":"10.1159/000540423","url":null,"abstract":"<p><strong>Introduction: </strong>Hidradenitis suppurativa is a chronic inflammatory disease of the apocrine gland-bearing areas frequently misdiagnosed or underdiagnosed. Its true prevalence is still unknown and there is an ongoing interest in this matter. The current study was a part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative that is actively involved in better understanding the epidemiological characteristics of HS.</p><p><strong>Methods: </strong>This study was a multicenter study in 2 tertiary care hospitals in Bucharest. After obtaining consent, data from 796 healthy accompanying adults were included. A validated screening questionnaire was used before the clinical examination of the screening-positive and randomly selected screening-negative participants, respectively.</p><p><strong>Results: </strong>The prevalence of hidradenitis suppurativa in Bucharest, Romania was 0.75% (95% confidence interval: [0.35%-1.63%]).</p><p><strong>Conclusion: </strong>There aren't any data available regarding the prevalence of hidradenitis suppurativa in Romania and the current report is the first paper addressing the prevalence of HS in the capital of Romania, Bucharest.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-5"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plant Extracts in Acne Management: a narrative review. 植物提取物在痤疮管理:叙述回顾。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000547149
Mathieu Leti, Lucile Garidou, Stéphane V Cuisiat, Aline Stennevin, Gautier Doat, Céline Mias
{"title":"Plant Extracts in Acne Management: a narrative review.","authors":"Mathieu Leti, Lucile Garidou, Stéphane V Cuisiat, Aline Stennevin, Gautier Doat, Céline Mias","doi":"10.1159/000547149","DOIUrl":"https://doi.org/10.1159/000547149","url":null,"abstract":"<p><strong>Background: </strong>Acne is a chronic inflammatory skin disease associated with impaired pilosebaceous unit function leading to the development of noninflammatory and inflammatory lesions and, in some cases, persistent post-inflammatory erythema, hyperpigmentation and scarring. Acne pathophysiology is complex, involving altered sebum production and composition, abnormal keratinization, microbiome dysbiosis, and skin inflammation. Conventional therapies, such as topical retinoids, antibiotics and benzoyl peroxide, are the first-line treatments for mild-to-moderate acne, but antibiotic resistance and local adverse effects can have a negative impact on therapeutic outcomes, leading to a growing interest in alternative strategies for disease management. The use of dermocosmetics is increasingly being recognized as a useful strategy to improve treatment outcomes and patient adherence. In particular, there has been a recent increase in research aiming to identify natural plant-based ingredients with properties that target the multiple pathogenic mechanisms involved in acne, but which have less impact on skin barrier function.</p><p><strong>Summary: </strong>This review provides a summary of the anti-acne properties of the most well-characterized plant extracts and phytocompounds used in dermocosmetic anti-acne products, based on insights gained from in vitro, ex vivo and in vivo studies. Evidence gained from clinical trials evaluating the effectiveness and safety of topical formulations containing these herbal ingredients is also presented. Finally, several less well-characterized herbal extracts and phytocompounds with promising anti-acne properties are described.</p><p><strong>Key messages: </strong>Although research is ongoing for many of the anti-acne herbal ingredients identified so far, this review highlights the effectiveness of topical plant-based formulations for reducing lesion counts and disease severity in acne patients, as well as the rebalancing effects of herbal ingredients on sebum composition, microbial diversity, and pilosebaceous unit cell differentiation. Taken together with the antibiofilm, anti-inflammatory, antioxidant, and skin barrier repair properties demonstrated for many of these extracts, current evidence suggests that dermocosmetics with plant-based ingredients show great promise for acne management, either as monotherapies, maintenance treatments, or in combination with conventional drugs.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-51"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hidradenitis Suppurativa in Antalya, Türkiye. 土耳其安塔利亚地区化脓性汗腺炎的流行情况。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000542480
Erkan Alpsoy, Sena Akanlar, Samir Naghiyev, Dorra Bouazzi, Caner Vardar, Oğuz Yılmaz, Robin Christensen, Gregor B E Jemec
{"title":"Prevalence of Hidradenitis Suppurativa in Antalya, Türkiye.","authors":"Erkan Alpsoy, Sena Akanlar, Samir Naghiyev, Dorra Bouazzi, Caner Vardar, Oğuz Yılmaz, Robin Christensen, Gregor B E Jemec","doi":"10.1159/000542480","DOIUrl":"10.1159/000542480","url":null,"abstract":"<p><strong>Introduction: </strong>Hidradenitis suppurativa (HS) prevalence studies show considerable regional discrepancies due to various methodological and/or ethnic factors. The prevalence of HS in Türkiye has yet to be examined. This study aimed to assess the HS prevalence with a validated screening questionnaire in Antalya-Türkiye as part of the major project to determine the global prevalence of HS.</p><p><strong>Methods: </strong>This single-center, cross-sectional study in a tertiary health institution was conducted among healthy volunteer adults accompanying patients in the internal medicine outpatient clinics of Akdeniz University between July and November 2022.</p><p><strong>Results: </strong>The study included 1,012 participants, 544 females, and 468 males. Seven participants (4 females and 3 males, median age 44.0 [IQR 40.5-54.5] years old) had HS, and the prevalence was 0.69% (95% confidence interval [0.33%-1.4%]). The proportion of HS at an early stage was higher than the rate previously reported from the same center in a registry research (Hurley I, 28.57% vs 16%). The examination of 110 screen-negative participants did not reveal any HS. There was no difference between HS patients and non-HS participants regarding gender, age, BMI, and daily smoking rate.</p><p><strong>Conclusion: </strong>HS prevalence in Antalya seems compatible with the global prevalence of the disease. This study did not confirm the male dominance observed in Türkiye in earlier studies. The HS patients diagnosed in the study represent a milder spectrum of the disease.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-4"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hidradenitis Suppurativa in Hospital Kuala Lumpur, Malaysia: A Cross-Sectional Study. 马来西亚吉隆坡医院化脓性汗腺炎的流行:一项横断面研究。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000539397
Moonyza Akmal Ahmad Kamil, Azahirafairud Abdul Rahim, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec
{"title":"Prevalence of Hidradenitis Suppurativa in Hospital Kuala Lumpur, Malaysia: A Cross-Sectional Study.","authors":"Moonyza Akmal Ahmad Kamil, Azahirafairud Abdul Rahim, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec","doi":"10.1159/000539397","DOIUrl":"10.1159/000539397","url":null,"abstract":"<p><strong>Introduction: </strong>Hidradenitis suppurativa (HS) is a painful, chronic, recurring, debilitating, inflammatory skin disease affecting the areas rich in apocrine glands, with typical lesions (abscesses, nodules, discharging sinuses, and scars) and distribution (intertriginous areas). The prevalence of HS varies across geographical locality with lower rates reported in Asia.</p><p><strong>Methods: </strong>A cross-sectional, descriptive study, involving 500 consecutive healthy adults in Hospital Kuala Lumpur (HKL), was done from December 2022 to April 2023, to estimate the prevalence of HS in HKL, via a validated questionnaire. We included healthy hospital staff and those accompanying patients in the Department of Medicine. Consented participants would answer the screening questionnaire for HS, as well as the socio-demographic data questionnaire. The screened-positive participants were evaluated by a dermatologist to confirm the diagnosis of HS and to take clinical photos.</p><p><strong>Results: </strong>Ten participants were screened-positive for HS, but only 7 were confirmed cases. The prevalence of this study was 7/500 (1.4%). Majority had mild diseases (71% Hurley stage 1, 29% Hurley stage 2). HS was more prevalent among males (n = 4), lower education level (n = 4), and Chinese ethnicity (n = 3). There was no significant difference among the HS participants when compared to non-HS participants based on their age, gender, education level, income status, BMI, or smoking status (p > 0.05).</p><p><strong>Conclusion: </strong>HS is a complex disease with multifactorial elements to consider in its pathogenesis. The availability for early detection of mild HS disease, via a validated screening questionnaire, may change the paradigm of management of HS in the future.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-7"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hidradenitis Suppurativa in Lyon: Results from the French Team of the Global Hidradenitis Suppurativa Atlas Project. 里昂化脓性汗腺炎的患病率:来自全球化脓性汗腺炎地图集项目法国团队的结果。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000542671
Philippe Guillem, Virginie Vlaeminck-Guillem, Marianne Beuque-Lévèque, Christelle Chavrier, Marion Clerbout, Christelle Enault, Inès Evain, Myriam Fioretta, Anne-Sophie Gadat, Samantha Gaspard, Sylvia Math, Gregor B E Jemec, Dorra Bouazzi
{"title":"Prevalence of Hidradenitis Suppurativa in Lyon: Results from the French Team of the Global Hidradenitis Suppurativa Atlas Project.","authors":"Philippe Guillem, Virginie Vlaeminck-Guillem, Marianne Beuque-Lévèque, Christelle Chavrier, Marion Clerbout, Christelle Enault, Inès Evain, Myriam Fioretta, Anne-Sophie Gadat, Samantha Gaspard, Sylvia Math, Gregor B E Jemec, Dorra Bouazzi","doi":"10.1159/000542671","DOIUrl":"10.1159/000542671","url":null,"abstract":"<p><strong>Introduction: </strong>The exact prevalence of hidradenitis suppurativa (HS) remains elusive, in France as elsewhere. The Global Hidradenitis Suppurativa Atlas (GHiSA) project is a unique opportunity not only to determine the exact prevalence in each participating center but also to help estimate the global prevalence and provide a basis for comparing centers with each other and obtaining potential pathophysiological indications.</p><p><strong>Methods: </strong>A French version of the questionnaire developed for the GHiSA initiative was proposed to healthy adults accompanying a patient to the outpatient clinic.</p><p><strong>Results: </strong>The prevalence of HS in the 525 participants was 3.43% (95% confidence interval: 2.2%-5.4%). The HS patients were 10 females and 8 males and were significantly younger than non-HS controls and more frequently smokers. The screening questionnaire showed a 100% sensitivity and negative predictive value.</p><p><strong>Conclusion: </strong>The estimated prevalence here is more than three times higher than the 1% prevalence usually recognized in Western countries. It remains to be determined whether this increase is apparent (freedom of speech; methodological differences compared with previous studies, which contribute to the usual figure of 1%) or real. In the latter case (gross increase in the prevalence of the disease), the underlying mechanisms need to be explored, and comparison with the results observed in other GHiSA centers will be decisive.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-5"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hidradenitis Suppurativa in the Gulf Province of Papua New Guinea. 巴布亚新几内亚海湾省化脓性汗腺炎的流行情况。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000538422
Nadja E Zorge, Johanna C van Huijstee, Jasper S Dijkema, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Errol P Prens, Hessel H van der Zee
{"title":"Prevalence of Hidradenitis Suppurativa in the Gulf Province of Papua New Guinea.","authors":"Nadja E Zorge, Johanna C van Huijstee, Jasper S Dijkema, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Errol P Prens, Hessel H van der Zee","doi":"10.1159/000538422","DOIUrl":"10.1159/000538422","url":null,"abstract":"<p><strong>Introduction: </strong>Hidradenitis suppurativa (HS) is a chronic and debilitating inflammatory skin disease, which mostly occurs in the skinfolds. The global prevalence of HS is currently unknown. Depending on the type of research and studied population, the reported prevalence varies between 0.03% and 4.1%. It is important to investigate the prevalence of HS worldwide using the same study design, in order to recognize, diagnose, and treat patients at an earlier stage. Consequently, a worldwide initiative, the Global Hidradenitis Suppurativa Atlas (GHiSA) has developed a study design to investigate the worldwide prevalence of HS in a comparable manner. The prevalence of HS in a Pacific Islander population has not been reported. The aim of this study was to estimate the prevalence of HS in Kapuna, Papua New Guinea.</p><p><strong>Methods: </strong>An explorative, descriptive, cross-sectional mono-center study in a secondary care center, the Kapuna Hospital, Papua New Guinea. Participants were healthy persons accompanying patients who were admitted to Kapuna Hospital or attending its Outpatient Department, and healthy hospital staff. The primary outcome of this study was the point prevalence of HS in Papua New Guinea using a validated questionnaire and physical examination.</p><p><strong>Results: </strong>A total of 520 participants were included in this study. The prevalence of HS in these 520 participants was 0.38% (2/520, 95% confidence interval 0.1-1.4%).</p><p><strong>Conclusion: </strong>The point prevalence of HS in Papua New Guinea was 0.38%. The findings of this study contribute to fill a gap in the current insights into global HS prevalence.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-6"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Hidradenitis Suppurativa in Athens, Greece: A Cross-Sectional Study Based on a Validated Questionnaire. 希腊雅典化脓性汗腺炎的流行:一项基于有效问卷的横断面研究。
IF 3 3区 医学
Dermatology Pub Date : 2025-07-07 DOI: 10.1159/000539758
Theodora Kanni, Sofia Ktena, Konstantinos Leventogiannis, Christina Damoulari, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Evangelos J Giamarellos-Bourboulis
{"title":"Prevalence of Hidradenitis Suppurativa in Athens, Greece: A Cross-Sectional Study Based on a Validated Questionnaire.","authors":"Theodora Kanni, Sofia Ktena, Konstantinos Leventogiannis, Christina Damoulari, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Evangelos J Giamarellos-Bourboulis","doi":"10.1159/000539758","DOIUrl":"10.1159/000539758","url":null,"abstract":"<p><strong>Introduction: </strong>Prevalence of hidradenitis suppurativa (HS) differs between countries and the worldwide prevalence of the disease remains unknown. Prevalence of HS has never been studied in Greece. The aim of this study was to estimate the HS prevalence in Athens, the capital of Greece.</p><p><strong>Method: </strong>Healthy adults accompanying patients to the outpatient department of internal medicine of ATTIKON University Hospital were approached by physicians familiar with HS. All eligible persons signed an informed consent form and answered the questionnaire. This study was a part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative and therefore followed the objective and approach previously published by Bouazzi et al. [Dermatology. 2024 Feb;240(3):369-75].</p><p><strong>Results: </strong>Out of 553 participants, 20 screened positive for HS. Of these, only one was diagnosed with HS, resulting in a prevalence of 0.18% (95% CI, 0.03%-1.02%). The sensitivity of the HS questionnaire was 100%, specificity 75.9%, positive predictive value 5.0%, and negative predictive value 100%.</p><p><strong>Conclusion: </strong>The prevalence of HS in our study was relatively low. A further study with a larger number of participants is needed to confirm the findings.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-5"},"PeriodicalIF":3.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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