Current Pediatric Research最新文献

{"title":"Value of Doppler ultrasonography in predicting renal pathology in children with chronic kidney disease.","authors":"Salwa Swelam, M. H. Mahgoob, M. Elian, M. Gayyed","doi":"10.35841/0971-9032.24.1.156-160","DOIUrl":"https://doi.org/10.35841/0971-9032.24.1.156-160","url":null,"abstract":"Background: Chronic kidney disease is a global health concern, its detection and diagnosis in earlier stages is also a great challenge that can alleviate this burden. Kidney biopsy is important to establish histopathological patterns. But, it's invasive. Objectives: Is to evaluate the correlation of renal resistive index (RI) measured by Doppler ultrasound with the progression of chronic kidney disease and to evaluate its significance as non-invasive marker of renal histological damage. Methods: This is a prospective cross sectional study included a total of 57 children; 38 patients with different stages of chronic kidney disease (Group I) and 19 healthy children served as controls (Group II). Full history, examinations and some laboratory investigations were done. All participants underwent renal Doppler ultrasonography and a kidney biopsy was taken from CKD patients. Results: Resistive index was significantly higher in patients group compared to control group. In CKD patients there was a significant positive correlation between RI and stages of CKD (r=0.47). Also there was a significant positive correlation between RI and histological indices. However, significant negative association was found between RI and both eGFR (r=-0.49) and renal length (r=-0.40). Conclusion: Resistive index increases with the progression of CKD and it is correlated with the histological indices. So, RI as a non-invasive technique could be considered as a marker of renal function and histological damage in CKD patients and it could be a non-invasive indicator for monitoring the progression of renal disease.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"24 1","pages":"156-160"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross reactivity between Cow’s and Camel’s milk in the infant population of Saudi Arabia","authors":"A. Aburiziza","doi":"10.35841/0971-9032.24.1.175-179","DOIUrl":"https://doi.org/10.35841/0971-9032.24.1.175-179","url":null,"abstract":"Objective: One of the most common types of allergy in the early childhood is cow’s milk allergy (CMA). Patients suffering from CMA may show severe allergic responses and therefore they have to follow a strict diet. Camel’s milk is different in protein composition as compared to cow’s milk and could be used as its substitute. Thus, in the present study we tried to identify patients with CMA and camel milk allergy and their cross reactivity in the Saudi Arabian infant population. Method: The patients below 2 years of age and diagnosed with CMA were recruited from two different hospitals of Saudi Arabia. Also demographic data were collected for all the patients. Electronic chart were reviewed for food allergy, milk allergy and anaphylaxis shock using the International Classification of Diseases (ICD) coding process. Results: A total of 112 patients were recruited for the study with male to female ratio of 1:33. The clinical presentations showed by the participants were atopic dermatitis (24%), chronic diarrhea (21%), anaphylaxis (16%), poor weight gain (16%), chronic vomiting (11%) and urticaria (5%). 108 patients showed positive results for Cow milk’s skin prick test and 2 patients showed positive Camel milk skin prick test. The cross reactivity between CMA and camel milk was low i.e., 108 to 2 prospectively. The Cow’s milk specific IgE was positive in 92% of participants with 25 ± 34 KU/L. Conclusion: If we can confirm positive CMA and confirm negative camel allergy by oral challenge, the results will be more reliable, and possibly we can determine the safety for suggesting camel milk for children suffering from CMA.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"52 1","pages":"175-179"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70026951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Past Conference Report Pediatrics Congress 2020","authors":"A. Willson","doi":"10.35841/0971-9032.6.1-1","DOIUrl":"https://doi.org/10.35841/0971-9032.6.1-1","url":null,"abstract":"The feat of 2nd International Webinar Conference on Pediatrics, Neonatology and Cardiac Care well thought-out by Allied Academies Ltd that was apprehended during July 13-14, 2020 was a tremendous standard. Massive number of participants from around the globe had spoken on various topics of their respective field’s diverse sessions. Aim: This great congress aids to pass on altogether fundamental instructional researchers, specialists and different studies undertaken to exchange and rate their assessments and studies results on all segments of Pediatrics. Moreover it presents a most valuable interdisciplinary stage for scientists, professionals Student researchers and teachers to offer and brief conversions about the greatest current technological advancements, patterns, and stresses notwithstanding despite sensible circumstances experienced and following the different insights in the fields of Pediatrics, Neonatal care and Cardiac care.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"24 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70028539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal Programming - New Insights into the Origins of Neurodegenerative Disorders.","authors":"A. Tarkowska, A. Ska","doi":"10.35841/0971-9032.24.6.225-229","DOIUrl":"https://doi.org/10.35841/0971-9032.24.6.225-229","url":null,"abstract":"Neurodegenerative diseases, including Alzheimer’s disease (AD), constitute a problem of great significance in aging societies. The origin and underlying causes have not been established yet. The lately discovered phenomenon of foetal programming explains the connection between perinatal episodes and the development of chronic diseases in the later stages of life. The aim of this review is to show that altered foetal programming may connect perinatal asphyxia and the development of AD later in life. It is believed that most cases of AD arise through interactions between genetic and environmental factors. Among all the exposures, transient brain hypoxia has been extensively studied recently. The role of hypoxia in the early developmental period as a trigger for developing AD in adults through altered programming of genes expression cannot be excluded. It is possible that severe hypoxia in early life can cause biochemical changes, including long-lasting alterations in gene expression, leading to neurodegenerative disorders in adults. The prevention of neurodegenerative diseases should focus on events from the earliest periods of life. Better recognition of underlying mechanisms is necessary for further investigations and the development of novel therapeutic methods.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"64 1","pages":"225-229"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kasabach-Merrit syndrome with congenital hemangioma.","authors":"Archana., M. ShafathAhmed, S. Sundari","doi":"10.35841/0971-9032.24.1.161-162","DOIUrl":"https://doi.org/10.35841/0971-9032.24.1.161-162","url":null,"abstract":"Haemangioma are vascular lesions resulting from abnormal proliferation of blood vessels they are the most common paediatric neoplasm. Haemangioma are congenital lesions that are common in new-borns infants and children. They are generally benign and often resolve spontaneously. However, in 3 to 5% of cases, they can cause complications inherent to their size, to involvement of vital organs and to the concomitant coagulopathy like KasabachMerritt syndrome. Kasabach Meritt Syndrome (KMS) is a potentially life threatening coagulopathy characterized by enlarging haemangioma with severe thrombocytopenia and consumption coagulopathy. KMS is associated with kaposiform hemangioendothelioma (KHE), tufted angiomas and rarely with congenital haemangiomas (CHs). Almost 200 cases have been reported in the literature since Kasabach and Merritt described the first case in 1940. More than 80% of cases occur within the first year of life.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"24 1","pages":"161-162"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexistence of vitiligo and psoriasis in a child with progressive familial intrahepatic cholestasis type 2.","authors":"Abdurrahman Ibrahim Almurayshid","doi":"10.35841/0971-9032.24.1.153-155","DOIUrl":"https://doi.org/10.35841/0971-9032.24.1.153-155","url":null,"abstract":"Progressive familial intrahepatic cholestasis type 2 (PIFC2) is a rare autosomal recessive liver disease. This article presents a 5-year-old girl with PIFIC2 who developed both vitiligo and psoriasis as co-localization. This coexistence of skin disorders may represent a new association with the genetic disease. No reports of this possible association have been previously published. The article overview relationships among Vitiligo, Psoriasis and Liver cholestasis.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"28 1","pages":"153-155"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70027142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Place of Birth on Knowledge of Neonatal Danger Signs and Associated Factors among Mother's in Meicha District, Northwest Ethiopia: A Community-based Comparative Cross-Sectional Study","authors":"T. G. Gebremeskel, A. Tsegaye, A. Geremew, Teklit Grum","doi":"10.21203/rs.2.19041/v1","DOIUrl":"https://doi.org/10.21203/rs.2.19041/v1","url":null,"abstract":"\u0000 Background: Danger signs in the neonatal period are non-specific and could be a manifestation of almost any newborn disease. Early recognition of these signs by mothers is a pre-request for increasing neonatal care-seeking behavior. There four this study aimed to assess knowledge of neonatal danger signs and associated factors among mothers who gave birth at home and health institutions in Meicha District, Northwest Ethiopia. Methods: A community based comparative cross-sectional study was conducted among Home and Health institutions delivered mothers two months before the survey. A simple random sampling method was used to select the participants. Data was collected by face to face interviews of mothers. Binary logistic regression analysis was used to identify associated factors. The odds ratio with 95% CI was computed to assess the strength of the associations. Result: A total of 650 (325 health institution delivered and 325 home delivered) mothers were interviewed. Among this, 50.7% (AOR=2.19, 95%, CI (1.594-3.003)) of the mother were knowledge of neonatal danger sign in the district. Mother knowledge of neonatal danger sign was higher among mothers who give birth health institution (60.1%) than home (41.1%). Age of the mother (AOR:3.99, 95% CI:(1.45-11.03)), age of new born (AOR:0.53, 95% CI:(0.36-0.78)), parity (AOR:1.27, 95% CI:(1.37-5.31)), postnatal care attendance (AOR=2.42,95% CI: (1.47, 3.96)), distance of health center (AOR:0.46,95% CI:(0.27,0.78)) were significantly associated with overall mother’s knowledge of neonatal danger sign. Whereas, residence (AOR: 3.09, 95% CI:(1.44, 6.64)) and occupational status of husband (AOR:0.23, 95% CI:(0.201,0.67)) were significantly associated with health institution delivered mother. Age of new born (AOR: 0.50, 95% CI:(0.28,0.896)), parity(AOR: 0.29, 95% CI:(0.113,0.74)), antenatal care (AOR: 12.04, 95% CI: (5.9,24.65)) and postnatal care attendance (AOR:0.27,95% CI:(0.138,0.51)) was significantly associated with home delivered mother. Conclusion: The overall mother’s knowledge of neonatal danger signs was low. However, health institutions delivered mother more knowledge about danger signs than home-delivered mothers. Therefore, it is better if the district Health Office should investigate the implementation of educational programs in the community and strengthen the health extension program.","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"25 1","pages":"642-651"},"PeriodicalIF":0.0,"publicationDate":"2019-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67947727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alpha-2-agonists for sedation in children","authors":"N. Almenrader","doi":"10.4066/0971-9032-C1-012","DOIUrl":"https://doi.org/10.4066/0971-9032-C1-012","url":null,"abstract":"","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70681337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal exposure to air pollution and childhood allergy","authors":"Qihong Deng","doi":"10.4066/0971-9032-C1-010","DOIUrl":"https://doi.org/10.4066/0971-9032-C1-010","url":null,"abstract":"","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70680443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the NICU-borders","authors":"Van Hoestenberghe Mr","doi":"10.4066/0971-9032-C1-011","DOIUrl":"https://doi.org/10.4066/0971-9032-C1-011","url":null,"abstract":"","PeriodicalId":11183,"journal":{"name":"Current Pediatric Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70680515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}