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Topical minoxidil in monilethrix. 局部使用米诺地尔治疗念珠菌。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247808
U Saxena, V Ramesh, R S Misra
{"title":"Topical minoxidil in monilethrix.","authors":"U Saxena, V Ramesh, R S Misra","doi":"10.1159/000247808","DOIUrl":"https://doi.org/10.1159/000247808","url":null,"abstract":"","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 4","pages":"252-3"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247808","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13044283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Drug-induced versus drug-triggered pemphigus. 药物诱导与药物引发的天疱疮。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247795
R Wolf, A Tamir, S Brenner
{"title":"Drug-induced versus drug-triggered pemphigus.","authors":"R Wolf,&nbsp;A Tamir,&nbsp;S Brenner","doi":"10.1159/000247795","DOIUrl":"https://doi.org/10.1159/000247795","url":null,"abstract":"<p><p>112 cases of induced pemphigus were reviewed. The causative drugs were divided into three groups according to their chemical structure, and the clinical, prognostic and laboratory characteristics were analyzed and compared. Our literature screening indicates that the biological progress and clinical course of the disease depend upon the type of the inducing/triggering drug in the majority of patients. Patients with penicillamine-induced pemphigus or with pemphigus induced by SH drugs (drugs containing a sulfhydryl radical) showed spontaneous recovery in 39.4 and 52.6%, respectively, once the drug was discontinued. Patients whose pemphigus was induced by other drugs showed spontaneous recovery in only 15% of the cases. These results indicate that in patients with pemphigus induced by penicillamine (or SH drugs), the drug plays a major role in the pathogenesis of the disease, as compared to patients with pemphigus induced by other drugs. It seems that penicillamine (and SH drugs) actually induces pemphigus in most of the cases, whereas other drugs only trigger the disease in patients with a previous predisposition.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 4","pages":"207-10"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247795","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13046424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 90
Sweat-related dermatoses: old concept and new scenario. 汗液相关皮肤病:旧概念和新情况。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247748
C H Hu
{"title":"Sweat-related dermatoses: old concept and new scenario.","authors":"C H Hu","doi":"10.1159/000247748","DOIUrl":"https://doi.org/10.1159/000247748","url":null,"abstract":"<p><p>This review focuses on dermatoses that are caused by the presence of sweat--a previously underemphasized subject. A working classification based on 'internal sweating' (extravasated sweat in the dermis and epidermis) and 'external sweating' (sweat on skin surface) is proposed. Clinical observations suggest that transient acantholytic dermatosis is the consequence of extravasated sweat; we speculate that it is an example of sweat-related, protease-induced epidermal acantholysis. Neutrophilic eccrine hidradenitis may represent a sweat-related drug reaction. We emphasize the well-recognized phenomenon of 'sweat retention syndrome' in a new scenario: hospitalized febrile patients, increasing use of chemotherapy, new life style. The concept of 'sweat-gland-mediated cutaneous inflammation' is proposed.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"182 2","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247748","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13206484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 32
Plexiform fibrohistiocytic tumor. 丛状纤维组织细胞瘤。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247703
F Giard, R Bonneau, G P Raymond
{"title":"Plexiform fibrohistiocytic tumor.","authors":"F Giard,&nbsp;R Bonneau,&nbsp;G P Raymond","doi":"10.1159/000247703","DOIUrl":"https://doi.org/10.1159/000247703","url":null,"abstract":"<p><p>Two groups of cells, one rounded or oval and the other spindle-shaped, were found in a case of plexiform fibrohistiocytic tumor. Immunohistochemistry was strongly positive for alpha smooth muscle actin in most cells of both types but stronger in the spindle-shaped cells, suggesting a myofibroblastic origin. This was in correlation with electron microscopic findings which revealed fibroblasts, myofibroblasts and some undifferentiated mesenchymal cells. However, factor XIIIa was negative suggesting that this tumor does not originate from dermal dendrocytes.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 4","pages":"290-3"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247703","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12832400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Immunophenotyping of skin cells during healing of suction blister injury. 吸式水疱损伤愈合过程中皮肤细胞的免疫表型分析。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247665
M K Reusch, J N Mansbridge, B J Nickoloff, V B Morhenn
{"title":"Immunophenotyping of skin cells during healing of suction blister injury.","authors":"M K Reusch,&nbsp;J N Mansbridge,&nbsp;B J Nickoloff,&nbsp;V B Morhenn","doi":"10.1159/000247665","DOIUrl":"https://doi.org/10.1159/000247665","url":null,"abstract":"<p><p>The time course of appearance and the dynamic changes of immunocompetent cells were assessed in human skin following sterile suction blister would healing. During epidermal regeneration, a local increase in Langerhans cells (LC) and the appearance of a mononuclear cell infiltrate were observed. Initially, T cells were exclusively of the T helper/inducer subtype, whereas during the later stages of the healing process an increasing number of cytotoxic/suppressor T cells (up to 30%) was observed. Keratinocytes of neither the adjacent nor the newly formed epidermis expressed HLA-DR over the course of the wound-healing process. Our results suggest that immune-competent cells such as T cells and LC may play an important role in the regulation of the wound-healing process.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 3","pages":"179-83"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247665","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12849138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
73rd Annual Meeting of the Swiss Society for Dermatology and Venereology. Abstracts. 第73届瑞士皮肤病和性病学会年会。摘要。
Dermatologica Pub Date : 1991-01-01
{"title":"73rd Annual Meeting of the Swiss Society for Dermatology and Venereology. Abstracts.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 4","pages":"297-307"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12851823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expression of c-myc in cutaneous lymphomas and pseudolymphomas. c-myc在皮肤淋巴瘤和假性淋巴瘤中的表达。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247622
K Peris, L Cerroni, H Kerl, T Radaszkiewicz, S Chimenti, H Höfler
{"title":"Expression of c-myc in cutaneous lymphomas and pseudolymphomas.","authors":"K Peris,&nbsp;L Cerroni,&nbsp;H Kerl,&nbsp;T Radaszkiewicz,&nbsp;S Chimenti,&nbsp;H Höfler","doi":"10.1159/000247622","DOIUrl":"https://doi.org/10.1159/000247622","url":null,"abstract":"<p><p>The expression of the proto-oncogene c-myc was studied in tumorous skin lesions of (cutaneous) lymphoproliferative diseases (3 cases of pseudolymphoma, 8 cases of non-Hodgkin lymphoma and 1 case of lymph node involvement in mycosis fungoides) in a total of 12 patients. c-myc mRNA levels were quantified by Northern blot analysis followed by densitometric evaluation of the specific bands. Higher levels of c-myc mRNA expression were observed in lymphomas as compared with pseudolymphomas (p greater than 0.05). No significant differences in c-myc mRNA values were detected between B and T cell pseudolymphomas. Our results suggest that c-myc mRNA overexpression is associated with malignant lymphomas of the skin. We conclude that the measurement of c-myc mRNA levels may contribute to further characterize cutaneous lymphoproliferative diseases.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247622","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12931518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Anticentromere antibody and Raynaud's phenomenon. 抗着丝点抗体和雷诺现象。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247635
L Czirják, J Schlammadinger, G Szegedi
{"title":"Anticentromere antibody and Raynaud's phenomenon.","authors":"L Czirják,&nbsp;J Schlammadinger,&nbsp;G Szegedi","doi":"10.1159/000247635","DOIUrl":"https://doi.org/10.1159/000247635","url":null,"abstract":"","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 1","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247635","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12932038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells. 角质形成细胞和汗腺细胞亚群细胞核中表皮生长因子受体的免疫组织化学表达。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247623
C Piérard-Franchimont, A Colige, J Arrese Estrada, C M Lapière, G E Piérard
{"title":"Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.","authors":"C Piérard-Franchimont,&nbsp;A Colige,&nbsp;J Arrese Estrada,&nbsp;C M Lapière,&nbsp;G E Piérard","doi":"10.1159/000247623","DOIUrl":"https://doi.org/10.1159/000247623","url":null,"abstract":"<p><p>We have raised a polyclonal antibody to the 170-kD epidermal growth factor receptor. We found an intercellular pattern of immunoreactivity in the epidermis as well as a positivity of the cytoplasm of keratinocytes and eccrine secretory cells. In some samples, a nuclear labelling was evidenced in these type of cells. There is a close resemblance in the topographical distribution of these cells with nuclear labelling and those synthesizing DNA under phytohaemagglutinin stimulation.</p>","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"183 1","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000247623","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12932042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Borrelia burgdorferi and different types of morphea. 伯氏疏螺旋体和不同类型的吗啡。
Dermatologica Pub Date : 1991-01-01 DOI: 10.1159/000247767
E. Aberer, H. Klade, G. Stanek, W. Gebhart
{"title":"Borrelia burgdorferi and different types of morphea.","authors":"E. Aberer, H. Klade, G. Stanek, W. Gebhart","doi":"10.1159/000247767","DOIUrl":"https://doi.org/10.1159/000247767","url":null,"abstract":"Thirty patients with different clinical manifestations of morphea (circumscribed scleroderma) were investigated for serum antibodies against Borrelia burgdorferi determined by ELISA and Western blot analysis. Forty-six percent of the patients were seropositive. Western blots confirmed the ELISA results in 10 of 25 patients (40%), showing a reactivity pattern which can be seen in the course of Lyme borreliosis. In some cases the outcome after antibiotic treatment suggests a direct correlation between the further development of skin lesions and Borrelia infection. Because of these findings we suggest some morphea types to be possibly due to a B. burgdorferi infection.","PeriodicalId":11117,"journal":{"name":"Dermatologica","volume":"33 1","pages":"145-54"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79445861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 65
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