Borrelia burgdorferi and different types of morphea.

Dermatologica Pub Date : 1991-01-01 DOI:10.1159/000247767
E. Aberer, H. Klade, G. Stanek, W. Gebhart
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引用次数: 65

Abstract

Thirty patients with different clinical manifestations of morphea (circumscribed scleroderma) were investigated for serum antibodies against Borrelia burgdorferi determined by ELISA and Western blot analysis. Forty-six percent of the patients were seropositive. Western blots confirmed the ELISA results in 10 of 25 patients (40%), showing a reactivity pattern which can be seen in the course of Lyme borreliosis. In some cases the outcome after antibiotic treatment suggests a direct correlation between the further development of skin lesions and Borrelia infection. Because of these findings we suggest some morphea types to be possibly due to a B. burgdorferi infection.
伯氏疏螺旋体和不同类型的吗啡。
对30例不同临床表现的局限性硬皮病(morphea,简称morphea)患者采用ELISA和Western blot检测伯氏疏螺旋体抗体。46%的患者血清呈阳性。免疫印迹证实了25例患者中10例(40%)的ELISA结果,显示在莱姆病病程中可见的反应性模式。在某些情况下,抗生素治疗后的结果表明皮肤病变的进一步发展与伯氏疏螺旋体感染之间存在直接关联。由于这些发现,我们认为一些morphea类型可能是由于伯氏疏螺旋体感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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