Current Treatment Options in Rheumatology最新文献

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Janus Kinase Inhibition and SLE: Is this a Plausible Treatment Option for SLE? Janus激酶抑制与SLE:这是一个合理的SLE治疗选择吗?
Current Treatment Options in Rheumatology Pub Date : 2020-10-24 DOI: 10.1007/s40674-020-00155-w
Ayida Al Khalili, J. Dutz
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引用次数: 3
Whiplash Injuries 脑震荡
Current Treatment Options in Rheumatology Pub Date : 2020-10-22 DOI: 10.1007/s40674-020-00162-x
R. Teasell, S. Mehta, Eldon Y. Loh
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引用次数: 1
Treatment Guidelines in Rheumatoid Arthritis—Optimizing the Best of Both Worlds 类风湿关节炎的治疗指南——两全其美
Current Treatment Options in Rheumatology Pub Date : 2020-10-13 DOI: 10.1007/s40674-020-00163-w
Aprajita Jagpal, J. Singh
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引用次数: 1
Is There a Role for Plasma Exchange in ANCA-Associated Vasculitis? 血浆置换在anca相关性血管炎中有作用吗?
Current Treatment Options in Rheumatology Pub Date : 2020-09-12 DOI: 10.1007/s40674-020-00161-y
M. Prendecki, S. McAdoo, C. Pusey
{"title":"Is There a Role for Plasma Exchange in ANCA-Associated Vasculitis?","authors":"M. Prendecki, S. McAdoo, C. Pusey","doi":"10.1007/s40674-020-00161-y","DOIUrl":"https://doi.org/10.1007/s40674-020-00161-y","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"1 1","pages":"313 - 324"},"PeriodicalIF":0.0,"publicationDate":"2020-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91182925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
An update on targets for treating osteoarthritis pain: NGF and TRPV1. 治疗骨关节炎疼痛靶点的最新进展:NGF和TRPV1。
Current Treatment Options in Rheumatology Pub Date : 2020-09-01 Epub Date: 2020-05-06 DOI: 10.1007/s40674-020-00146-x
Alia M Obeidat, Anita Donner, Rachel E Miller
{"title":"An update on targets for treating osteoarthritis pain: NGF and TRPV1.","authors":"Alia M Obeidat,&nbsp;Anita Donner,&nbsp;Rachel E Miller","doi":"10.1007/s40674-020-00146-x","DOIUrl":"https://doi.org/10.1007/s40674-020-00146-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>a)Osteoarthritis (OA) is the most common form of arthritis, and pain is the primary symptom of the disease, yet analgesic options for treating OA pain remain limited. In this review, we aimed to give an update on the current clinical and preclinical studies targeting two pathways that are being investigated for treating OA pain: the nerve growth factor (NGF) pathway and the transient receptor potential vanilloid-1 (TRPV1) pathway.</p><p><strong>Recent findings: </strong>b)Antibodies against NGF, small molecule inhibitors of TrkA, TRPV1 agonists, and TRPV1 antagonists are all in different stages of clinical and pre-clinical testing for the treatment of OA pain. NGF antibodies have shown efficacy in the primary endpoints tested compared to placebo, however, rapidly progressive OA has been consistently observed in a subset of patients and the cause remains unclear. TRPV1 agonists have also demonstrated reduced pain with no serious adverse events - the most common adverse events include a burning or warming sensation upon administration.</p><p><strong>Summary: </strong>c)Targeting the NGF and TRPV1 pathways appear effective for reducing OA pain, but further work is needed to better understand which patients may benefit most from these treatments. The anti-NGF antibody tanezumab and the TRPV1 agonist CNTX-4975 have both received fast-track designation from the FDA for the treatment of OA pain.</p>","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"6 3","pages":"129-145"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40674-020-00146-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39112963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
New Treatments in Rheumatology: Biosimilars 风湿病的新疗法:生物类似药
Current Treatment Options in Rheumatology Pub Date : 2020-08-17 DOI: 10.1007/s40674-020-00159-6
R. Brasington, V. Strand
{"title":"New Treatments in Rheumatology: Biosimilars","authors":"R. Brasington, V. Strand","doi":"10.1007/s40674-020-00159-6","DOIUrl":"https://doi.org/10.1007/s40674-020-00159-6","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"66 1","pages":"325 - 336"},"PeriodicalIF":0.0,"publicationDate":"2020-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82231261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Macrophage Activation Syndrome in Childhood Inflammatory Disorders: Diagnosis, Genetics, Pathophysiology, and Treatment 儿童炎性疾病中的巨噬细胞激活综合征:诊断、遗传学、病理生理学和治疗
Current Treatment Options in Rheumatology Pub Date : 2020-08-07 DOI: 10.1007/s40674-020-00153-y
F. Baldo, G. Beretta, J. Tibaldi, R. Caorsi, F. Minoia
{"title":"Macrophage Activation Syndrome in Childhood Inflammatory Disorders: Diagnosis, Genetics, Pathophysiology, and Treatment","authors":"F. Baldo, G. Beretta, J. Tibaldi, R. Caorsi, F. Minoia","doi":"10.1007/s40674-020-00153-y","DOIUrl":"https://doi.org/10.1007/s40674-020-00153-y","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"93 1","pages":"245 - 259"},"PeriodicalIF":0.0,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76506963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publisher Correction: Characteristics, Treatment Options, and Outcomes of Chronic Non-Bacterial Osteomyelitis in Children 儿童慢性非细菌性骨髓炎的特点、治疗方案和结局
Current Treatment Options in Rheumatology Pub Date : 2020-08-05 DOI: 10.1007/s40674-020-00158-7
R. Kraus, R. Laxer
{"title":"Publisher Correction: Characteristics, Treatment Options, and Outcomes of Chronic Non-Bacterial Osteomyelitis in Children","authors":"R. Kraus, R. Laxer","doi":"10.1007/s40674-020-00158-7","DOIUrl":"https://doi.org/10.1007/s40674-020-00158-7","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"46 1","pages":"223 - 227"},"PeriodicalIF":0.0,"publicationDate":"2020-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83942242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Nonmedical Therapeutic Approaches in the Rehabilitation of Complex Regional Pain Syndrome 非药物治疗方法在复杂局部疼痛综合征康复中的作用
Current Treatment Options in Rheumatology Pub Date : 2020-07-29 DOI: 10.1007/s40674-020-00156-9
C. Boichat, A. Llewellyn, S. Grieve, C. McCabe
{"title":"The Role of Nonmedical Therapeutic Approaches in the Rehabilitation of Complex Regional Pain Syndrome","authors":"C. Boichat, A. Llewellyn, S. Grieve, C. McCabe","doi":"10.1007/s40674-020-00156-9","DOIUrl":"https://doi.org/10.1007/s40674-020-00156-9","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"16 1","pages":"299-311"},"PeriodicalIF":0.0,"publicationDate":"2020-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83328059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cost-Effectiveness of Arthroplasty Management in Hip and Knee Osteoarthritis: a Quality Review of the Literature 髋关节和膝关节骨性关节炎关节置换术治疗的成本-效果:文献质量综述
Current Treatment Options in Rheumatology Pub Date : 2020-07-23 DOI: 10.1007/s40674-020-00157-8
C. Primeau, Ishita Joshi, B. Zomar, L. Somerville, H. Philpott, David D. McHugh, B. Lanting, E. Vasarhelyi, Jacquelyn D. Marsh
{"title":"Cost-Effectiveness of Arthroplasty Management in Hip and Knee Osteoarthritis: a Quality Review of the Literature","authors":"C. Primeau, Ishita Joshi, B. Zomar, L. Somerville, H. Philpott, David D. McHugh, B. Lanting, E. Vasarhelyi, Jacquelyn D. Marsh","doi":"10.1007/s40674-020-00157-8","DOIUrl":"https://doi.org/10.1007/s40674-020-00157-8","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"33 1","pages":"160 - 190"},"PeriodicalIF":0.0,"publicationDate":"2020-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90269697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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