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Current Treatment Options in Rheumatology最新文献

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Vascular Interventions in Takayasu Arteritis 高安动脉炎的血管介入治疗
Current Treatment Options in Rheumatology Pub Date : 2024-07-23 DOI: 10.1007/s40674-024-00216-4
M. D. de Aguiar, Andressa Miozzo Soares, Alexandre Wagner Silva de Souza
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引用次数: 0
(Levamisole Adulterated) Cocaine-Induced Vasculitis: What Is Known/Current Evidence (左旋咪唑掺假）可卡因诱发的血管炎：已知信息/现有证据
Current Treatment Options in Rheumatology Pub Date : 2024-07-23 DOI: 10.1007/s40674-024-00215-5
Johan W. J. Donkers, Robert A. Feijen, Abraham Rutgers
{"title":"(Levamisole Adulterated) Cocaine-Induced Vasculitis: What Is Known/Current Evidence","authors":"Johan W. J. Donkers, Robert A. Feijen, Abraham Rutgers","doi":"10.1007/s40674-024-00215-5","DOIUrl":"https://doi.org/10.1007/s40674-024-00215-5","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"122 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141812033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous Immunoglobulins in Idiopathic Inflammatory Myopathies: Where Are We? 特发性炎症性肌病中的静脉注射免疫球蛋白：我们在哪里？
Current Treatment Options in Rheumatology Pub Date : 2024-01-10 DOI: 10.1007/s40674-023-00214-y
Kevin Gourbeyre-Masson, O. Landon-Cardinal, Olivier Benveniste, Yves Allenbach
{"title":"Intravenous Immunoglobulins in Idiopathic Inflammatory Myopathies: Where Are We?","authors":"Kevin Gourbeyre-Masson, O. Landon-Cardinal, Olivier Benveniste, Yves Allenbach","doi":"10.1007/s40674-023-00214-y","DOIUrl":"https://doi.org/10.1007/s40674-023-00214-y","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"6 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139440194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Immune-Mediated Necrotizing Myopathy. 免疫介导的坏死性肌病的治疗。
Current Treatment Options in Rheumatology Pub Date : 2023-12-01 Epub Date: 2023-07-13 DOI: 10.1007/s40674-023-00210-2
Sandra Amara Ogbonnaya-Whittlesey, Dale Kobrin, Maria Casal-Dominguez, Andrew L Mammen, Iago Pinal-Fernandez
{"title":"Treatment of Immune-Mediated Necrotizing Myopathy.","authors":"Sandra Amara Ogbonnaya-Whittlesey, Dale Kobrin, Maria Casal-Dominguez, Andrew L Mammen, Iago Pinal-Fernandez","doi":"10.1007/s40674-023-00210-2","DOIUrl":"10.1007/s40674-023-00210-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>Immune-mediated necrotizing myositis (IMNM) is a rare autoimmune disorder characterized by proximal muscle weakness, elevated creatine kinase levels, and necrosis of muscle fibers. While the exact pathogenesis of IMNM remains unknown, anti-HMGCR and anti-SRP autoantibodies are associated with different predisposing factors, clinical manifestations, and severity of the disease and are believed to correspond to two pathogenically distinct entities. The cornerstone treatment for IMNM is a combination of glucocorticoids and steroid-sparing agents. Therapeutic strategies aimed at decreasing the half-life of endogenous autoantibodies, such as intravenous immunoglobulin (IVIG), or reducing their production, such as rituximab, have shown promise as powerful treatments. In severe cases, combining IVIG and rituximab can have synergistic effects.</p><p><strong>Recent findings: </strong>Previous studies suggested that complement dysregulation may be involved in the pathogenesis of IMNM. However, a recent phase 2 clinical trial evaluating the effectiveness of zilucoplan, a C5 inhibitor, failed to show efficacy in IMNM.</p><p><strong>Summary: </strong>In this review, we aim to provide a comprehensive review of IMNM focusing on the current evidence regarding treatment options for this condition. Our goal is to present an up-to-date overview of the current state of therapeutics on IMNM and highlight potential areas for future investigation.</p>","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"4 1","pages":"168-178"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12346690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74634949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Myositis Associated With Immune Checkpoint Inhibitors 免疫检查点抑制剂治疗肌炎
Current Treatment Options in Rheumatology Pub Date : 2023-11-02 DOI: 10.1007/s40674-023-00212-0
Ana Matas-García, Eugenia Martinez-Hernandez, José César Milisenda
{"title":"Treatment of Myositis Associated With Immune Checkpoint Inhibitors","authors":"Ana Matas-García, Eugenia Martinez-Hernandez, José César Milisenda","doi":"10.1007/s40674-023-00212-0","DOIUrl":"https://doi.org/10.1007/s40674-023-00212-0","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"16 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135935131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Mechanisms Underlying Systemic Sclerosis–Associated Interstitial Lung Disease and Idiopathic Pulmonary Fibrosis: an Update 系统性硬化症相关间质性肺疾病和特发性肺纤维化的分子机制研究进展
Current Treatment Options in Rheumatology Pub Date : 2023-10-18 DOI: 10.1007/s40674-023-00213-z
Priyanka Verma, Swarna Bale, John Varga, Swati Bhattacharyya
{"title":"Molecular Mechanisms Underlying Systemic Sclerosis–Associated Interstitial Lung Disease and Idiopathic Pulmonary Fibrosis: an Update","authors":"Priyanka Verma, Swarna Bale, John Varga, Swati Bhattacharyya","doi":"10.1007/s40674-023-00213-z","DOIUrl":"https://doi.org/10.1007/s40674-023-00213-z","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135885056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Greater Trochanteric Pain Syndrome: Clinical Presentation, Diagnosis, and Management 大转子疼痛综合征:临床表现、诊断和治疗
Current Treatment Options in Rheumatology Pub Date : 2023-08-08 DOI: 10.1007/s40674-023-00209-9
Romain Guemara, M. Nissen
{"title":"The Greater Trochanteric Pain Syndrome: Clinical Presentation, Diagnosis, and Management","authors":"Romain Guemara, M. Nissen","doi":"10.1007/s40674-023-00209-9","DOIUrl":"https://doi.org/10.1007/s40674-023-00209-9","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85824182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-articular Therapies for Knee Osteoarthritis: Current Update 膝关节骨关节炎的关节内治疗:最新进展
Current Treatment Options in Rheumatology Pub Date : 2023-07-01 DOI: 10.1007/s40674-023-00207-x
Win Min Oo, J. Hunter
{"title":"Intra-articular Therapies for Knee Osteoarthritis: Current Update","authors":"Win Min Oo, J. Hunter","doi":"10.1007/s40674-023-00207-x","DOIUrl":"https://doi.org/10.1007/s40674-023-00207-x","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"1 1","pages":"99 - 119"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73248154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment? 患者偏好和骨关节炎护理:我们知道患者想从骨关节炎治疗中得到什么?
Current Treatment Options in Rheumatology Pub Date : 2023-06-19 DOI: 10.1007/s40674-023-00208-w
P. Nicolson, M. Holden
{"title":"Patient Preferences and Osteoarthritis Care: What Do We Know About What Patients Want from Osteoarthritis Treatment?","authors":"P. Nicolson, M. Holden","doi":"10.1007/s40674-023-00208-w","DOIUrl":"https://doi.org/10.1007/s40674-023-00208-w","url":null,"abstract":"","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":"171 1","pages":"120 - 131"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89318622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Exercise Therapy for Knee and Hip Osteoarthritis: Is There An Ideal Prescription? 膝关节和髋关节骨性关节炎的运动疗法：有理想的处方吗？
Current Treatment Options in Rheumatology Pub Date : 2023-05-20 DOI: 10.1007/s40674-023-00205-z
James J Young, Julie Rønne Pedersen, Alessio Bricca
{"title":"Exercise Therapy for Knee and Hip Osteoarthritis: Is There An Ideal Prescription?","authors":"James J Young,&nbsp;Julie Rønne Pedersen,&nbsp;Alessio Bricca","doi":"10.1007/s40674-023-00205-z","DOIUrl":"10.1007/s40674-023-00205-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>Exercise therapy is the first line treatment for patients with knee and hip osteoarthritis (OA) but is consistently underutilized. In this review, we aim to provide health care professionals with an overview of the latest evidence in the areas of exercise therapy for OA, which can serve as a guide for incorporating the ideal exercise therapy prescription in the overall management plan for their patients with OA.</p><p><strong>Recent findings: </strong>Evidence continues to be produced supporting the use of exercise therapy for all patients with knee or hip OA. Ample evidence exists suggesting exercise therapy is a safe form of treatment, for both joint structures and the patient overall. Several systematic reviews show that exercise therapy is likely to improve patient outcomes, regardless of disease severity or comorbidities. However, no single type of exercise therapy is superior to others.</p><p><strong>Summary: </strong>Health care practitioners and patients should be encouraged to incorporate exercise therapy into treatment plans and can be assured of the safety profile and likelihood of improvement in important patient outcomes. Since no single exercise therapy program shows vastly superior benefit, patient preference and contextual factors should be central to the shared decision-making process when selecting and individualising appropriate exercise therapy prescriptions.</p>","PeriodicalId":11096,"journal":{"name":"Current Treatment Options in Rheumatology","volume":" ","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2023-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10199279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9719861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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