Current Opinion in Pulmonary Medicine最新文献_第10页

How do we expand the lung donor pool? 如何扩大肺捐献者库？

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-07-01 Epub Date: 2024-03-28 DOI: 10.1097/MCP.0000000000001076

Bronwyn J Levvey, Gregory I Snell

{"title":"How do we expand the lung donor pool?","authors":"Bronwyn J Levvey, Gregory I Snell","doi":"10.1097/MCP.0000000000001076","DOIUrl":"10.1097/MCP.0000000000001076","url":null,"abstract":"Purpose of review: Lung transplantation activity continues to be limited by the availability of timely quality donor lungs. It is apparent though that progress has been made. The steady evolution of clinical practice, combined with painstaking scientific discovery and innovation are described.Recent findings: There have been successful studies reporting innovations in the wider use and broader consideration of donation after circulatory death donor lungs, including an increasing number of transplants from each of the controlled, uncontrolled and medically assisted dying donor descriptive categories. Donors beyond age 70 years are providing better than expected long-term outcomes. Hepatitis C PCR positive donor lungs can be safely used if treated postoperatively with appropriate antivirals. Donor lung perfusion at a constant 10 degrees appears capable of significantly improving donor logistics and ex-vivo lung perfusion offers the potential of an ever-increasing number of novel donor management roles. Bioartificial and xenografts remain distant possibilities only at present.Summary: Donor lungs have proved to be surprisingly robust and combined with clinical, scientific and engineering innovations, the realizable lung donor pool is proving to be larger than previously thought.","PeriodicalId":11090,"journal":{"name":"Current Opinion in Pulmonary Medicine","volume":" ","pages":"398-404"},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An update of palliative care in lung transplantation with a focus on symptoms, quality of life and functional outcomes. 肺移植姑息治疗的最新进展，重点关注症状、生活质量和功能结果。

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-07-01 Epub Date: 2024-03-27 DOI: 10.1097/MCP.0000000000001075

Dmitry Rozenberg, Rogih Riad Andrawes, Kirsten Wentlandt

{"title":"An update of palliative care in lung transplantation with a focus on symptoms, quality of life and functional outcomes.","authors":"Dmitry Rozenberg, Rogih Riad Andrawes, Kirsten Wentlandt","doi":"10.1097/MCP.0000000000001075","DOIUrl":"10.1097/MCP.0000000000001075","url":null,"abstract":"Purpose of review: Palliative care (PC) in lung transplantation is increasingly acknowledged for its important role in addressing symptoms, enhancing functionality, and facilitating advance care planning for patients, families, and caregivers. The present review provides an update in PC management in lung transplantation.Recent findings: Research confirms the effectiveness of PC for patients with advanced lung disease who are undergoing transplantation, showing improvements in symptoms and reduced healthcare utilization. Assessment tools and patient-reported outcome measures for PC are commonly used in lung transplant candidates, revealing discrepancies between symptom severity and objective measures such as exercise capacity. The use of opioids to manage dyspnea and cough in the pretransplant period is deemed safe and does not heighten risks posttransplantation. However, the integration of PC support in managing symptoms and chronic allograft dysfunction in the posttransplant period has not been as well described.Summary: Palliative care support should be provided in the pretransplant and select peri-operative and posttransplant periods to help support patient quality of life, symptoms, communication and daily function.","PeriodicalId":11090,"journal":{"name":"Current Opinion in Pulmonary Medicine","volume":" ","pages":"410-418"},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140293123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lung transplantation: practical and important directions of care. 肺移植：实用而重要的护理方向。

IF 2.8 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-07-01 Epub Date: 2024-05-30 DOI: 10.1097/MCP.0000000000001081

Allan R Glanville, Carli J Lehr

引用次数: 0

Disparities across the continuum of lung cancer care: a review of recent literature. 肺癌治疗过程中的差异：最新文献综述。

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-07-01 Epub Date: 2024-02-23 DOI: 10.1097/MCP.0000000000001064

Lauren Kearney, Tatyana Nguyen, Katrina Steiling

{"title":"Disparities across the continuum of lung cancer care: a review of recent literature.","authors":"Lauren Kearney, Tatyana Nguyen, Katrina Steiling","doi":"10.1097/MCP.0000000000001064","DOIUrl":"10.1097/MCP.0000000000001064","url":null,"abstract":"Purpose of review: Lung cancer remains the leading cause of cancer mortality worldwide. Health disparities have long been noted in lung cancer incidence and survival and persist across the continuum of care. Understanding the gaps in care that arise from disparities in lung cancer risk, screening, treatment, and survivorship are essential to guiding efforts to achieve equitable care.Recent findings: Recent literature continues to show that Black people, women, and people who experience socioeconomic disadvantage or live in rural areas experience disparities throughout the spectrum of lung cancer care. Contributing factors include structural racism, lower education level and health literacy, insurance type, healthcare facility accessibility, inhaled carcinogen exposure, and unmet social needs. Promising strategies to improve lung cancer care equity include policy to reduce exposure to tobacco smoke and harmful pollutants, more inclusive lung cancer screening eligibility criteria, improved access and patient navigation in lung cancer screening, diagnosis and treatment, more deliberate offering of appropriate surgical and medical treatments, and improved availability of survivorship and palliative care.Summary: Given ongoing disparities in lung cancer care, research to determine best practices for narrowing these gaps and to guide policy change are an essential focus of future lung cancer research.","PeriodicalId":11090,"journal":{"name":"Current Opinion in Pulmonary Medicine","volume":" ","pages":"359-367"},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139971342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The changing landscape of infections in the lung transplant recipient. 肺移植受者感染情况的变化。

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-07-01 Epub Date: 2024-02-26 DOI: 10.1097/MCP.0000000000001060

Jessica Lum, Christine Koval

{"title":"The changing landscape of infections in the lung transplant recipient.","authors":"Jessica Lum, Christine Koval","doi":"10.1097/MCP.0000000000001060","DOIUrl":"10.1097/MCP.0000000000001060","url":null,"abstract":"Purpose of review: Infections in lung transplant recipients remain a major challenge and can affect lung allograft function and cause significant morbidity and mortality. New strategies for the prevention and treatment of infection in lung transplantation have emerged and are reviewed.Recent findings: For important vaccine preventable infections (VPIs), guidance has been updated for at risk solid organ transplant (SOT) recipients. However, data on the efficacy of newer vaccines in lung transplant, including the respiratory syncytial virus (RSV) vaccine, are limited. Studies demonstrate improved vaccination rate with Infectious Diseases consultation during pretransplant evaluation. Two new antiviral agents for the treatment and prevention of cytomegalovirus (CMV) in SOT, letermovir and maribavir, are being incorporated into clinical care. CMV-specific cell-mediated immune function assays are more widely available. Antibiotics for the management of multidrug resistant pathogens and Burkholderia cepacia complex have been described in case series and case reports in lung transplant.Summary: Although new vaccines and novel therapies for preventing and treating infections are available, larger studies evaluating efficacy in lung transplant recipients are needed.","PeriodicalId":11090,"journal":{"name":"Current Opinion in Pulmonary Medicine","volume":" ","pages":"382-390"},"PeriodicalIF":3.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139971258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrated management of stage III in nonsmall cell lung cancer: where do perioperative chemotherapy and immunotherapy fit? 非小细胞肺癌 III 期的综合治疗：围手术期化疗和免疫疗法该何去何从？

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-07-01 Epub Date: 2024-05-07 DOI: 10.1097/MCP.0000000000001079

Ana Collazo-Lorduy, Mariola Blanco, Virginia Calvo, Mariano Provencio

引用次数: 0

The role of oscillometry in asthma. 振荡测量法在哮喘中的作用。

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-05-01 Epub Date: 2024-02-15 DOI: 10.1097/MCP.0000000000001057

Patrick A Donohue, David A Kaminsky

{"title":"The role of oscillometry in asthma.","authors":"Patrick A Donohue, David A Kaminsky","doi":"10.1097/MCP.0000000000001057","DOIUrl":"10.1097/MCP.0000000000001057","url":null,"abstract":"Purpose of review: Oscillometry is a noninvasive pulmonary function test that has gained significant interest in the evaluation of lung disease. Currently, oscillometry is primarily a research tool, but there is a growing body of evidence supporting its clinical use. This review describes the recent work evaluating the role of oscillometry in the diagnosis and treatment of asthma.Recent findings: A large body of observational data supports the ability of oscillometry to distinguish healthy individuals from those with respiratory symptoms or lung disease. Oscillometry may not be as useful as an isolated diagnostic test in asthma, but the combination with other pulmonary function tests may improve its diagnostic ability. Oscillometry can detect peripheral airways dysfunction in asthma, which is associated with symptoms and the risk for exacerbations. To help guide future research, minimal clinically important differences for specific oscillometry variables have been developed. Oscillometry may be useful in monitoring the response to biological therapy and has potential for personalizing treatment for individual patients. Oscillometry also has potential in uncovering unique aspects of the pathophysiology of asthma in obesity.Summary: Oscillometry is a promising tool in the diagnosis and management of asthma. More research is needed to support its routine clinical use.","PeriodicalId":11090,"journal":{"name":"Current Opinion in Pulmonary Medicine","volume":" ","pages":"268-275"},"PeriodicalIF":3.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139971259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lung abscess: an update on the current knowledge and call for future investigations. 肺脓肿：现有知识的更新和未来研究的呼吁。

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-05-01 Epub Date: 2024-02-19 DOI: 10.1097/MCP.0000000000001058

Søren Sperling, Victor Naestholt Dahl, Andreas Fløe

引用次数: 0

Remission in asthma. 哮喘缓解

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-05 DOI: 10.1097/MCP.0000000000001068

Marek Lommatzsch

{"title":"Remission in asthma.","authors":"Marek Lommatzsch","doi":"10.1097/MCP.0000000000001068","DOIUrl":"10.1097/MCP.0000000000001068","url":null,"abstract":"Purpose of review: To review the current concepts of remission in asthma.Recent findings: Until 2023, asthma guidelines have been promoting the concept of disease control, recommending the step-wise addition of drugs until the best possible disease control is achieved. With the advent of highly effective, anti-inflammatory disease-modifying antiasthmatic drugs (DMAADs), treatment goals of asthma have changed. Several national guidelines have now announced remission as a general treatment goal in asthma. Currently, all guidelines agree that asthma remission is defined by the presence of at least three characteristics over a period of at least one 1 year: absence of exacerbations, no systemic corticosteroid use for the treatment of asthma and minimal asthma-related symptoms. In the future, a generally accepted, evidence-based and easy-to-use definition of remission will be needed for daily clinical practice. It is clear, however, that precise phenotyping (including measurement of biomarkers) is an essential prerequisite to achieve clinical remission in each individual patient.Summary: Remission has been included as the treatment goal in asthma in several national guidelines, reflecting the paradigm shift in asthma, from short-term symptom control to long-term symptom prevention. An international consensus on the criteria for asthma remission is expected in the near future.","PeriodicalId":11090,"journal":{"name":"Current Opinion in Pulmonary Medicine","volume":" ","pages":"325-329"},"PeriodicalIF":3.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140027623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asthma in pregnancy: a review of recent literature. 妊娠期哮喘：最新文献综述。

IF 3.3 3区医学

Current Opinion in Pulmonary Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-13 DOI: 10.1097/MCP.0000000000001072

Kelly Colas, Jennifer Namazy

引用次数: 0