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Current Pharmacogenomics and Personalized Medicine最新文献

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A Prospective Observational Pilot Study of Adverse Drug Reactions in Patients Admitted in the Geriatric Ward of a Tertiary Hospital in North India 印度北部一家三级医院老年病房住院患者药物不良反应的前瞻性观察试验研究
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-05-31 DOI: 10.2174/1875692116666180830124924
Upinder Kaur, S. Chakrabarti, Bhanupriya Singh, I. Gambhir
{"title":"A Prospective Observational Pilot Study of Adverse Drug Reactions in Patients Admitted in the Geriatric Ward of a Tertiary Hospital in North India","authors":"Upinder Kaur, S. Chakrabarti, Bhanupriya Singh, I. Gambhir","doi":"10.2174/1875692116666180830124924","DOIUrl":"https://doi.org/10.2174/1875692116666180830124924","url":null,"abstract":"","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87955543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Herbal Drug Discovery: Challenges and Perspectives 草药药物发现:挑战与展望
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-03-31 DOI: 10.2174/1875692116666180419153313
S. Parasuraman
{"title":"Herbal Drug Discovery: Challenges and Perspectives","authors":"S. Parasuraman","doi":"10.2174/1875692116666180419153313","DOIUrl":"https://doi.org/10.2174/1875692116666180419153313","url":null,"abstract":"DOI: 10.2174/1875692116666180419153313 Abstract: Plants are very useful to mankind, and many plants are exclusively used by humans for medical purposes to prevent or treat diseases. In recent decades, natural products including medicinal plants have gained major attention in the pharmaceutical research field. Medicinal plants are the richest and commonly available sources for drug discovery. Many pharmaceutical lead molecules are derived from plants. The cost of the treatment, duration of illness and adverse effect/ toxicity of allopathic drugs cause an increase in the use of alternative systems of medicines, which lead to the drastic development of herbal drugs industry. The estimated market for pharma and pharma products in 2022 is $1.12 trillion and this indicates the global pharma needs. This may be due to changes in lifestyle and increased risk of infection globally. The World Health Organization recommends the practice of the traditional system of medicine as it is affordable, safe and culturally acceptable. The objective of this review article is to summarize the importance of plants in drug discovery, current perspectives and challenges.","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75550084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Validation of Traditional Medicinal Practices through Modern Scientific Tools and Techniques 通过现代科学工具和技术验证传统医学实践
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-03-31 DOI: 10.2174/187569211601180716105632
V. Kothari
{"title":"Validation of Traditional Medicinal Practices through Modern Scientific Tools and Techniques","authors":"V. Kothari","doi":"10.2174/187569211601180716105632","DOIUrl":"https://doi.org/10.2174/187569211601180716105632","url":null,"abstract":"","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79782673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Revisiting the in-vitro Assays for Antifungal Evaluation of Natural Products 天然产物体外抗真菌评价试验的再探讨
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-03-31 DOI: 10.2174/1875692116666180405144630
V. Saibabu, Z. Fatima, S. Hameed
{"title":"Revisiting the in-vitro Assays for Antifungal Evaluation of Natural Products","authors":"V. Saibabu, Z. Fatima, S. Hameed","doi":"10.2174/1875692116666180405144630","DOIUrl":"https://doi.org/10.2174/1875692116666180405144630","url":null,"abstract":"","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"2016 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73831256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pharmacovigilance in Ayurveda – Concept and Regulations 阿育吠陀的药物警戒-概念和法规
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-03-31 DOI: 10.2174/1875692116666180419153658
Janmejaya Samal
{"title":"Pharmacovigilance in Ayurveda – Concept and Regulations","authors":"Janmejaya Samal","doi":"10.2174/1875692116666180419153658","DOIUrl":"https://doi.org/10.2174/1875692116666180419153658","url":null,"abstract":"DOI: 10.2174/1875692116666180419153658 Abstract: Background: The Indian system of medicine has its origin in India and has been practiced since centuries in India and its neighbouring South East Asian countries. Mostly the practice of this system of medicine is believed to be the safest form of therapy, however, incidences of adverse drug reactions owing to the consumption of traditional drugs led to the origin of pharmacovigilance of Ayurvedic drugs.","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73133811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Alternative to Antibiotics from Herbal Origin - Outline of a Comprehensive Research Project 从草药来源替代抗生素-一个综合研究项目大纲
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-03-31 DOI: 10.2174/1875692116666180419154033
S. Pattanayak
{"title":"Alternative to Antibiotics from Herbal Origin - Outline of a Comprehensive Research Project","authors":"S. Pattanayak","doi":"10.2174/1875692116666180419154033","DOIUrl":"https://doi.org/10.2174/1875692116666180419154033","url":null,"abstract":"","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87609117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
The Gut Microbiota in Cardiovascular Diseases: From Biomarkers and Potential Targets to Personalized Interventions 心血管疾病中的肠道微生物群:从生物标志物和潜在目标到个性化干预
Current Pharmacogenomics and Personalized Medicine Pub Date : 2018-03-31 DOI: 10.2174/1875692116666180511170329
Yaroslav I. Ashikhmin, A. Syrkin, A. Zamyatnin, Yong Zhang, P. Kopylov
{"title":"The Gut Microbiota in Cardiovascular Diseases: From Biomarkers and Potential Targets to Personalized Interventions","authors":"Yaroslav I. Ashikhmin, A. Syrkin, A. Zamyatnin, Yong Zhang, P. Kopylov","doi":"10.2174/1875692116666180511170329","DOIUrl":"https://doi.org/10.2174/1875692116666180511170329","url":null,"abstract":"Ilyinsky Hospital, 143421, Moscow Region, Russia; Preventive and Urgent Cardiology Department, Sechenov First Moscow State Medical University, 119991, Moscow, Russia; Institute of Molecular Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia; Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology, Moscow, 119992, Russia; Institute of Personalized Medicine, Sechenov First Moscow State Medical University, 119991, Moscow, Russia; Department of Pharmacology, Harbin Medical University, Harbin, China","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82066600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Dynamic Biomarkers of Response to Antiangiogenic Therapies in Colorectal Cancer: A Review. 结直肠癌抗血管生成疗法反应的动态生物标志物：综述。
Current Pharmacogenomics and Personalized Medicine Pub Date : 2017-12-01 DOI: 10.2174/1875692115666170815161754
Jesus Rodriguez-Pascual, Antonio Cubillo
{"title":"Dynamic Biomarkers of Response to Antiangiogenic Therapies in Colorectal Cancer: A Review.","authors":"Jesus Rodriguez-Pascual, Antonio Cubillo","doi":"10.2174/1875692115666170815161754","DOIUrl":"10.2174/1875692115666170815161754","url":null,"abstract":"<p><strong>Background: </strong>Identification of clinical and molecular biomarkers to predict dynamic response or monitor in real-time the efficacy of antiangiogenic therapy represents a major point in the treatment of patients with advanced colorectal cancer. Several stu-dies have been conduced to identify some predictive biomarkers to select patients who will benefit from bevacizumab, the most widely used antiangiogenic monoclonal anti-body.</p><p><strong>Conclusion: </strong>After a decade since the introduction of bevacizumab, no effective predictive biomarkers are available in routine clinical practice. In this review, we summarized the potential candidate dynamic biomarkers that may play a role in this setting.</p>","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"15 2","pages":"81-85"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/c1/CPPM-15-81.PMC5872368.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36012371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: “New Challenges in the Treatment of Cardiovascular Diseases: From Evidence-based Medicine to Personalized Care” 社论:《心血管疾病治疗的新挑战:从循证医学到个性化护理》
Current Pharmacogenomics and Personalized Medicine Pub Date : 2017-06-23 DOI: 10.2174/187569211501170623153022
V. Conti
{"title":"Editorial: “New Challenges in the Treatment of Cardiovascular Diseases: From Evidence-based Medicine to Personalized Care”","authors":"V. Conti","doi":"10.2174/187569211501170623153022","DOIUrl":"https://doi.org/10.2174/187569211501170623153022","url":null,"abstract":"","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"117 1","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2017-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79417861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iodinated Contrast Media in Diagnostic Imaging: Cardiovascular Side Effects 碘造影剂在诊断成像中的作用:心血管副作用
Current Pharmacogenomics and Personalized Medicine Pub Date : 2017-06-23 DOI: 10.2174/1875692115666170503111700
G. Grezia, G. Gatta, T. Iannaccone, R. Grassi
{"title":"Iodinated Contrast Media in Diagnostic Imaging: Cardiovascular Side Effects","authors":"G. Grezia, G. Gatta, T. Iannaccone, R. Grassi","doi":"10.2174/1875692115666170503111700","DOIUrl":"https://doi.org/10.2174/1875692115666170503111700","url":null,"abstract":"","PeriodicalId":11056,"journal":{"name":"Current Pharmacogenomics and Personalized Medicine","volume":"39 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75704723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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