Herbal Drug Discovery: Challenges and Perspectives

Abstract

DOI: 10.2174/1875692116666180419153313 Abstract: Plants are very useful to mankind, and many plants are exclusively used by humans for medical purposes to prevent or treat diseases. In recent decades, natural products including medicinal plants have gained major attention in the pharmaceutical research field. Medicinal plants are the richest and commonly available sources for drug discovery. Many pharmaceutical lead molecules are derived from plants. The cost of the treatment, duration of illness and adverse effect/ toxicity of allopathic drugs cause an increase in the use of alternative systems of medicines, which lead to the drastic development of herbal drugs industry. The estimated market for pharma and pharma products in 2022 is $1.12 trillion and this indicates the global pharma needs. This may be due to changes in lifestyle and increased risk of infection globally. The World Health Organization recommends the practice of the traditional system of medicine as it is affordable, safe and culturally acceptable. The objective of this review article is to summarize the importance of plants in drug discovery, current perspectives and challenges.