{"title":"[Regulation of peptide hydrolase activity in psoriasis].","authors":"A P Suworow","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Clinico-biological examination of 154 patients with psoriasis resulted in data showing high activity of endo- and exopeptidases in efflorescences of that dermatosis. This was accompanied by depressed activity of trypsin inhibitor. At the same time magnesium deficiency, polysaccharide decrease and leucocyte increase were stated to be in the focus of skin damage. That character of interrelation, which play an important role in the pathogenesis of this widespread skin disease, is demonstrated.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 7","pages":"393-7"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13408688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I Popov, G M Müller, M Miehe, G Lewin, R von Baehr
{"title":"[Relation between the anti-oxidative potential of psoriasis blood plasma in reactivity of granulocytes].","authors":"I Popov, G M Müller, M Miehe, G Lewin, R von Baehr","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was revealed a positive correlation between an antioxidative potential (AP) of blood plasma from psoriasis patients and generation of O2- by normal granulocytes, stimulated by zymosan or aggregated human gamma-globulin, in the presence of the same plasma samples. The AP of plasma was measured by means of inhibition of the chemiluminescence arising during photoautoxidation of luminol. The production of O2- after cell stimulation was estimated by means of the reduction of tetrazolium salt. The result is discussed from the viewpoint of informative-regulatory role of the plasma AP for the white blood cells as a part of the whole organism, participating in its common defence reactions.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 1","pages":"43-8"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13461617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of structure of hapten carrying model substances on contact reaction: DNP conjugates of stereoisomers of alpha-alanine following DNCB sensitization].","authors":"G Schwartze, D Lübbe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By means of epicutaneous tests under standard conditions we studied the cell-mediated contact sensitivity to dinitrophenyl (DNP) conjugates of the stereoisomeric amino acids L-alpha-alanine and D-alpha-alanine, respectively, in patients sensitized with dinitrochlorobenzene (DNCB). There was no difference in the number of positive skin responses with the two enantiomeric compounds DNP-L-alpha-alanine (16/26) and DNP-D-alpha-alanine (17/26). However, as in earlier studies, no patient has shown a positive reaction to the position-isomeric DNP-beta-alanine.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 10","pages":"609-13"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13234439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Cytotoxic effect on human keratinocytes caused by anti-Ro-(SS-A) antibodies and UVA in vitro].","authors":"I Brink, F Böhm, H Meffert, N Sönnichsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is supposed that anti-Ro(SS-A) antibodies play an important role in the development of photosensitive skin disease in subacute cutaneous lupus erythematosus and neonatal lupus erythematosus. The aim of the experiments was to demonstrate that anti-Ro(SS-A) antibodies and UVA-light cause a cytotoxic effect on human keratinocytes in vitro. Keratinocytes are irradiated with UVA-light in presence of serum containing anti-Ro(SS-A) antibodies (62 E, ELISA). After application of 20 J/cm2 UVA-light only 48.5% of the irradiated cells are still vital (standard trypan blue exclusions test). Examination by scanning electron microscopy shows plain depressions on the surface of the keratinocytes, which were irradiated in presence of anti-Ro(SS-A) antibodies.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 11","pages":"701-6"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13239150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[History of leprosy in Erfurt].","authors":"H R Abe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Erfurt, one of the greatest towns of Germany in the middle ages, the leprosy rules from the beginning of the 13th to the beginning of the 17th century: a appearance, which was then typical for the development of this malady in Germany. The leprosy-patients was isolated in special hospitals. Her number vacillated between four and two.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 12","pages":"765-70"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13249485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Photoallergic contact eczema caused by 4-isopropyldibenzoylmethane].","authors":"H Jacobi, B Pinzer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dibenzoylmethanes are widely used in UVA absorbing sunscreens but also in cosmetics protecting against skin aging. We report on a 25 years old female with photoallergic contact dermatitis caused by 4-Isopropyl-dibenzoylmethane (Eusolex 8020, Merck), who had taken Contralum Ultra Creme because of a polymorphic light eruption.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 11","pages":"669-72"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13304246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Bandage as a drug carrier--successful treatment of superficial thrombophlebitis with pentosan polysulfate].","authors":"J Hadlich, H P Klöcking, R Linse, W Schunk","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 4","pages":"233-4"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12861315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[10th congress of the Society for Dermatology of GDR with international participation. Dresden, October 31-November 2, 1990. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 9","pages":"525-84"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13136374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Dermatophyte infections caused by Microsporum canis and Microsporum audouinii in the Greifswald area].","authors":"G Schröder, K Hein, A Herrmann, M Pambor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Report of serial diseases of dermatophytoses caused by M. canis (5 patients) and M. audouinii (9 patients). Two cats and a dog were the infective source of M. canis-infection. M. audouinii-infection was stated in a children ward; here the infective source had not been detected. Remarkable are the identical morphological lesions of tinea capitis resp. corporis and the affections of adults in the two groups of patients. Griseofulvin therapy and additional veterinary hygienical treatment in case of M. canis-infection the two endemis were dissipated in few weeks.</p>","PeriodicalId":11046,"journal":{"name":"Dermatologische Monatschrift","volume":"176 2-3","pages":"115-21"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13512965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}