{"title":"Delayed lymphoscintigraphy for sentinel node mapping following wide local excision in primary melanoma.","authors":"Amitabh Thacoor, Pennylouise Hever, Allan Ponniah","doi":"10.25251/5jazxh53","DOIUrl":"10.25251/5jazxh53","url":null,"abstract":"<p><p>Sentinel lymph node biopsy (SLNB) is used in the staging of melanoma and is generally performed at the time of wide local excision (WLE) of the primary lesion, the location of which guides preoperative and intraoperative lymphatic mapping. However, the role of delayed lymphatic mapping following prior WLE remains unclear. We report the case of a patient who underwent lymphoscintigraphy before and after WLE for melanoma, compare the findings, and review the published literature. A 32-year-old woman was scheduled for WLE and SLNB of a 2.0-mm Breslow thickness melanoma on the upper arm. After her preoperative lymphoscintigram, an unplanned pregnancy was diagnosed, and she elected to proceed with WLE alone. She later requested delayed SLNB and underwent a second lymphoscintigram 2 months later. Comparison of the pre- and post-WLE lymphoscintigrams demonstrated variation in the location and number of sentinel lymph nodes, raising important questions about the accuracy of delayed lymphatic mapping and SLNB in melanoma. This report adds to the understanding of lymphatic channel behavior following WLE and may help inform decision-making for patients and clinicians.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles Hojjat, Isha Jhingan, Francesca L Veon, Jeffrey McBride
{"title":"Epithelioid angiosarcoma of the scalp: An advanced and rare presentation.","authors":"Charles Hojjat, Isha Jhingan, Francesca L Veon, Jeffrey McBride","doi":"10.25251/qxe6h291","DOIUrl":"10.25251/qxe6h291","url":null,"abstract":"<p><p>Epithelioid angiosarcoma (EA) is a rare, aggressive vascular malignancy that often presents with nonspecific cutaneous findings, leading to delayed diagnosis. We report the case of a 73-year-old man with a persistent, painful lesion on the vertex and parietal scalp that failed to respond to multiple courses of antibiotics and topical therapies for presumed infectious and inflammatory dermatoses. Examination revealed crusted erosions and plaques with a nodular component, initially mimicking chronic inflammatory skin disease or a potentially neoplastic entity. Histopathologic evaluation of a punch biopsy demonstrated sheets of atypical epithelioid cells with marked nuclear pleomorphism and frequent mitoses. Immunohistochemical staining confirmed endothelial origin with diffuse positivity for ERG and CD31, while excluding squamous, melanocytic, lymphoid, and epithelial neoplasms. These findings established the diagnosis of EA. The patient was referred for oncology evaluation and initiated on radiation therapy. Cutaneous EA most commonly affects elderly White men and arises on the scalp or face. Prognosis remains poor, with 5-year survival rates below 15% because of high recurrence and early metastatic potential. This case underscores the importance of maintaining a high index of suspicion for EA in nonhealing scalp lesions and highlights the central role of histopathology and immunohistochemistry in establishing the diagnosis.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer M Fernandez, Evelyn F Fagan, Jennifer L Adams, Erin X Wei
{"title":"How we do it: Untangling the web of inpatient biopsy supplies from ambulatory clinics.","authors":"Jennifer M Fernandez, Evelyn F Fagan, Jennifer L Adams, Erin X Wei","doi":"10.25251/x2ahc944","DOIUrl":"https://doi.org/10.25251/x2ahc944","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical site infection with <i>Mycobacterium fortuitum</i> following Mohs micrographic surgery in an immunocompromised patient and review.","authors":"David X Gao, Natalia E Plotnikova","doi":"10.25251/7vwq0s81","DOIUrl":"10.25251/7vwq0s81","url":null,"abstract":"<p><p><i>Mycobacterium fortuitum (M. fortuitum)</i> is a rare infection typically occurring in immunocompromised patients and in healthcare settings, primarily after surgery or exposure to contaminated medical equipment or tap water. A few cases have been reported following cutaneous procedures, including acupuncture, mesotherapy, and tattooing, although no report, to our knowledge, has been described after Mohs micrographic surgery (MMS). Treatment typically requires at least 2 oral antibiotics for several months owing to the persistent nature of the infection. We present a patient who had previously undergone MMS with bilobed flap and developed infection with <i>M. fortuitum</i>, treated with moxifloxacin 400 mg daily and trimethoprim-sulfamethoxazole 400 mg/80 mg daily.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Y Liu, Philip Scumpia, Catherine Ni, Sharona Yashar, Kathy Langevin, Yuna Kang, Amy Vandiver
{"title":"A diagnostically challenging case of pemphigus foliaceus without histologic evidence of acantholysis.","authors":"Jennifer Y Liu, Philip Scumpia, Catherine Ni, Sharona Yashar, Kathy Langevin, Yuna Kang, Amy Vandiver","doi":"10.25251/4gj9fp73","DOIUrl":"10.25251/4gj9fp73","url":null,"abstract":"<p><p>A 77-year-old woman presented with pruritic, scaly, erythematous papules and plaques on the face, which subsequently spread to the trunk. Over nearly 2 years, 5 skin biopsies were performed, consistently suggesting a subacute to chronic eczematous process without acantholysis or intraepidermal bullae. After 2 years of unsuccessful treatment, enzyme-linked immunosorbent assay demonstrated elevated anti desmoglein-1 IgG and normal anti desmoglein-3 IgG. Direct immunofluorescence of a skin biopsy revealed IgG and C3 deposition in the intercellular spaces. A diagnosis of pemphigus foliaceus was established, and the patient was treated with rituximab, resulting in significant clinical improvement. This case illustrates a diagnostically challenging presentation of pemphigus foliaceus in which multiple biopsies failed to demonstrate acantholysis or intraepidermal bullae (classic histologic features) highlighting the importance of immunologic testing in the evaluation of suspected autoimmune blistering disorders.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustainability in dermatology: Practical interventions across the care pathway.","authors":"Sara Lovasz, James Doherty","doi":"10.25251/dr6kaw20","DOIUrl":"https://doi.org/10.25251/dr6kaw20","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Josiah Williams, Veronica Emmerich, Shane Reynal, Courtney Heron, Stephanie Snyder, Matthew Johnson, Rima Ghamrawi, Jessica Savas, Phillip Williford, Steven Feldman
{"title":"Pre-Mohs micrographic surgery anxiety is higher in first-time and facial surgery patients.","authors":"Josiah Williams, Veronica Emmerich, Shane Reynal, Courtney Heron, Stephanie Snyder, Matthew Johnson, Rima Ghamrawi, Jessica Savas, Phillip Williford, Steven Feldman","doi":"10.25251/jcnemh86","DOIUrl":"https://doi.org/10.25251/jcnemh86","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zane Attard, Bettina Booker, David Borg, Daniel Micallef, Lawrence Scerri, Duncan Aquilina
{"title":"The role of surgical skin grafting in pyoderma gangrenosum.","authors":"Zane Attard, Bettina Booker, David Borg, Daniel Micallef, Lawrence Scerri, Duncan Aquilina","doi":"10.25251/eh2cnd59","DOIUrl":"https://doi.org/10.25251/eh2cnd59","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reactive eccrine syringofibroadenoma in an elderly patient.","authors":"Valbona Zeneli, Arben Zeneli, Ermira Vasili, Sabina Dedej","doi":"10.25251/e3se2k28","DOIUrl":"10.25251/e3se2k28","url":null,"abstract":"<p><p>Eccrine syringofibroadenoma (ESFA) is an uncommon benign adnexal tumor with eccrine differentiation, with fewer than 100 cases reported worldwide. Since its initial description, several clinical subtypes have been recognized, including a reactive form associated with chronic inflammatory or neoplastic conditions. We report the case of an 88-year-old man with extensive reactive ESFA developing in the setting of long-standing postthrombotic lymphedema and neglected ulceration. The patient presented with poor general health, bilateral pleural effusions, multiple verrucous nodules, severe stasis ulcers, and secondary polymicrobial and fungal infections. Histopathologic examination of a nodule demonstrated interconnecting cords of cuboidal epithelial cells with ductal structures within a fibrovascular stroma, consistent with eccrine differentiation and diagnostic of ESFA. Management focused on infection control, wound care, and supportive therapy, as surgical excision and amputation were not suitable options. Clinical improvement was achieved; however, ongoing monitoring was advised because of the potential for malignant transformation. This case highlights the role of chronic tissue injury in the pathogenesis of reactive ESFA and underscores the importance of histopathology for diagnosis, multidisciplinary collaboration in management, and individualized treatment planning in elderly patients with advanced comorbidities.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}