Dermatology online journal最新文献

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Nivolumab-induced hidradenitis suppurativa: a case report. 尼沃鲁单抗致化脓性汗腺炎1例。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464106
Olivia Lamberg, Karan Pandher, Natalie H Matthews
{"title":"Nivolumab-induced hidradenitis suppurativa: a case report.","authors":"Olivia Lamberg, Karan Pandher, Natalie H Matthews","doi":"10.5070/D330464106","DOIUrl":"https://doi.org/10.5070/D330464106","url":null,"abstract":"<p><p>We present a 44-year-old man with metastatic clear cell renal cell cancer undergoing treatment with nivolumab immunotherapy. Three months post-initiation, he developed symmetric recurrent nodules and boils in intertriginous areas, diagnosed as stage II hidradenitis suppurativa of the groin and gluteal cleft. The progressive course, lesion symmetry and location, worsening with nivolumab infusions, and biopsy findings supported the diagnosis. Hidradenitis suppurativa pathogenesis involves immune dysregulation marked by elevated IL17 and neutrophil-dominated inflammation [1]. Immune checkpoint inhibitors, including anti-PD1 agents like nivolumab, are linked to immune-related adverse events related to widespread T cell activation, potentially increasing IL17 signaling associated with HS [2,3]. Clinicians should be aware of, and observant for anti-PD1-induced HS, a rare immune-related adverse event, in patients undergoing immune checkpoint inhibitor therapy.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rapidly-growing friable nodule on the cheek. 脸颊上迅速生长的易碎的结节。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464116
Melissa C Leeolou, Peter A Young, Iesha L Ticknor, Jinping Lai, Ricardo T Paniagua, Robert L Burns
{"title":"A rapidly-growing friable nodule on the cheek.","authors":"Melissa C Leeolou, Peter A Young, Iesha L Ticknor, Jinping Lai, Ricardo T Paniagua, Robert L Burns","doi":"10.5070/D330464116","DOIUrl":"https://doi.org/10.5070/D330464116","url":null,"abstract":"<p><p>Atypical fibroxanthoma and pleomorphic dermal sarcoma are on a spectrum of cutaneous tumors that present as ulcerated lesions in older adults. We present an 84-year-old man with pleomorphic dermal sarcoma, initially presenting as a bleeding lesion of the cheek that progressed to an eroded nodule.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Annular secondary syphilis with HIV coinfection that resembles other dermatoses. 环状继发性梅毒与HIV合并感染,类似于其他皮肤病。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464109
Nabila Kirtti Pradipta, Devi Artami Susetiati, Hafidzah Nurmastuti, Retno Danarti, Satiti Retno Pudjiati
{"title":"Annular secondary syphilis with HIV coinfection that resembles other dermatoses.","authors":"Nabila Kirtti Pradipta, Devi Artami Susetiati, Hafidzah Nurmastuti, Retno Danarti, Satiti Retno Pudjiati","doi":"10.5070/D330464109","DOIUrl":"https://doi.org/10.5070/D330464109","url":null,"abstract":"<p><p>Syphilis is a sexually transmitted infection with manifestations that can mimic other diseases, leading to misdiagnosis. Annular syphilis is a rare atypical secondary syphilitic lesion that seldomly involves the face. Human immunodeficiency virus (HIV) coinfection can increasingly lead to atypical manifestations of syphilis and complicate the diagnosis. Herein, we describe a 29-year-old man with a diagnosis of annular secondary syphilis and HIV coinfection. He had clinical manifestations of annular erythematous papules and plaques with white scales at the edges, distributed and scattered on the face, neck, and upper back. The skin lesions went undetected on several visits and were misdiagnosed owing to similarities with other dermatoses. Serological examination showed positive Treponema pallidum particle agglutination assay and venereal disease research laboratory test titer 1/512, confirming syphilis infection. Results from the histopathological examination supported the diagnosis of secondary syphilis. Positive anti-HIV rapid test results indicated concurrent HIV infection. He was treated for syphilis and given antiretroviral therapy, and showed a good response as demonstrated by improvement of the lesions and serological titers. This case highlights the importance of recognizing the possibility of annular secondary syphilis and HIV coinfection which can have atypical manifestations.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Supravenous and perivenous distribution of a benign pigmented purpuric eruption. 良性色素紫癜疹的静脉上及静脉周围分布。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464123
Yoshihiro Matsudate
{"title":"Supravenous and perivenous distribution of a benign pigmented purpuric eruption.","authors":"Yoshihiro Matsudate","doi":"10.5070/D330464123","DOIUrl":"https://doi.org/10.5070/D330464123","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates in the prevention of glucocorticoid-induced adverse effects. 预防糖皮质激素引起的不良反应的最新进展。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464122
Callie Cunningham, Allison Limmer, Dario Kivelevitch
{"title":"Updates in the prevention of glucocorticoid-induced adverse effects.","authors":"Callie Cunningham, Allison Limmer, Dario Kivelevitch","doi":"10.5070/D330464122","DOIUrl":"https://doi.org/10.5070/D330464122","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Folliculotropic and syringotropic mycosis fungoides mimicking basal cell carcinoma. 仿基底细胞癌的嗜滤泡性和嗜筒性真菌病。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464115
Claudia Quarshie, Brittney DeClerck, Jenny C Hu
{"title":"Folliculotropic and syringotropic mycosis fungoides mimicking basal cell carcinoma.","authors":"Claudia Quarshie, Brittney DeClerck, Jenny C Hu","doi":"10.5070/D330464115","DOIUrl":"https://doi.org/10.5070/D330464115","url":null,"abstract":"<p><p>Mycosis fungoides (MF) is characterized by a clonal proliferation of skin-homing mature T cells with special predilection for involving the epidermis. Folliculotropic and syringotropic MF typically present with erythematous papules, patches, and plaques, with punctate accentuation that is folliculocentric in the former. We report a 67-year-old woman, with an extensive history of allergic contact dermatitis, who was referred to the Mohs surgery clinic with a large pink plaque extending from the nasal bridge to the right upper medial cheek concerning for basal cell carcinoma. An outside punch biopsy showed benign basaloid follicular neoplasm. The patient was found to also have indurated erythematous plaques of the bilateral upper arms and erythematous scaly patches of bilateral arms and legs, abdomen, lateral trunk, buttocks, and groin. Owing to concern for possible cutaneous lymphoma, punch biopsies were performed which revealed the diagnosis of folliculotropic and syringotropic MF. Of note, folliculotropic and syringotropic MF are often, but not uniformly, characterized by a more aggressive disease course. This case highlights the importance of a high index of suspicion and awareness of all clinical and histopathologic pitfalls to avoid misdiagnosis of MF.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orange palpebral spots on bilateral upper eyelids. 双侧上眼睑桔黄色斑。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464121
Madison Hackley, Nicholas Brownstone, Christina Sun, Sylvia Hsu
{"title":"Orange palpebral spots on bilateral upper eyelids.","authors":"Madison Hackley, Nicholas Brownstone, Christina Sun, Sylvia Hsu","doi":"10.5070/D330464121","DOIUrl":"https://doi.org/10.5070/D330464121","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the effectiveness of ChatGPT4 in the diagnosis and workup of dermatologic conditions. 评价ChatGPT4在皮肤病诊断和检查中的有效性。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464104
Charlotte Greif, Ndanzia Mpunga, Irene V Koopman, Allison Pye, Chad M Hivnor, Joshua L Owen
{"title":"Evaluating the effectiveness of ChatGPT4 in the diagnosis and workup of dermatologic conditions.","authors":"Charlotte Greif, Ndanzia Mpunga, Irene V Koopman, Allison Pye, Chad M Hivnor, Joshua L Owen","doi":"10.5070/D330464104","DOIUrl":"https://doi.org/10.5070/D330464104","url":null,"abstract":"<p><p>ChatGPT is a publicly available chatbot released by OpenAI. Its usefulness in responding to medical questions has been assessed in several specialties, but there is limited literature in dermatology. This study seeks to understand how well ChatGPT4 can provide accurate diagnoses and appropriate workup suggestions for clinical vignettes describing common dermatologic conditions. Ten vignettes were input into ChatGPT4 representing presentations of common dermatologic conditions, written from the perspective of a physician not board-certified in dermatology. ChatGPT4 was asked to identify the top five most likely diagnoses and its recommended workup for each vignette. Responses were assessed quantitatively by calculating the percentage of correct diagnoses, with accurate diagnoses defined by three board-certified dermatologists, and qualitatively using Likert scales describing the accuracy of diagnoses and appropriateness of workups scored by eleven board-certified dermatologists. Overall, 52% of ChatGPT4's diagnoses were accurate and 62% of its recommended workup suggestions were deemed completely correct by board-certified dermatologists. ChatGPT4 was better at recommending an appropriate workup than identifying accurate diagnoses across vignettes. ChatGPT4 was able to accurately diagnose and workup common dermatologic conditions in slightly more than half of cases. ChatGPT4 was better at determining an appropriate workup than an accurate diagnosis.Keywords: artificial intelligence, ChatGPT, dermatology, diagnosis, OpenAI, workup.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pyoderma gangrenosum after breast reduction surgery. 缩乳手术后坏疽性脓皮病。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464119
Eudora Lee, Subin Lim, Erika Elliott, Gabriela A Cobos
{"title":"Pyoderma gangrenosum after breast reduction surgery.","authors":"Eudora Lee, Subin Lim, Erika Elliott, Gabriela A Cobos","doi":"10.5070/D330464119","DOIUrl":"https://doi.org/10.5070/D330464119","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balancing beneficence and autonomy: The dilemma of unsolicited medical advice in dermatology. 平衡慈善和自主:在皮肤病学主动医疗建议的困境。
Dermatology online journal Pub Date : 2024-08-15 DOI: 10.5070/D330464124
Kritin K Verma, Ryan S Koch, Mojahed Mk Shalabi, Palak K Parekh
{"title":"Balancing beneficence and autonomy: The dilemma of unsolicited medical advice in dermatology.","authors":"Kritin K Verma, Ryan S Koch, Mojahed Mk Shalabi, Palak K Parekh","doi":"10.5070/D330464124","DOIUrl":"https://doi.org/10.5070/D330464124","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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