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Prescription trends of antipsychotic medications in dermatology among Medicare patients, 2013-2020. 2013-2020年医疗保险患者皮肤科抗精神病药物处方趋势
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664699
Katie Roster, Katherine M Erickson, Alina Zufall, Frederick A Pereira
{"title":"Prescription trends of antipsychotic medications in dermatology among Medicare patients, 2013-2020.","authors":"Katie Roster, Katherine M Erickson, Alina Zufall, Frederick A Pereira","doi":"10.5070/D330664699","DOIUrl":"https://doi.org/10.5070/D330664699","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acquired reactive perforating collagenosis in skin of color. 有色皮肤获得性反应性穿孔性胶原病。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664686
Spencer P McClure, William Liakos, Edward W Seger, Maryam Abdo, Abigail Murray, Ryan Gillihan
{"title":"Acquired reactive perforating collagenosis in skin of color.","authors":"Spencer P McClure, William Liakos, Edward W Seger, Maryam Abdo, Abigail Murray, Ryan Gillihan","doi":"10.5070/D330664686","DOIUrl":"10.5070/D330664686","url":null,"abstract":"<p><p>Acquired reactive perforating collagenosis is an uncommon disorder that present as keratotic plugs on the skin owing to transepidermal perforation of dermal connective tissue. Etiology is unclear, although the condition has been associated with renal disease, diabetes, and HIV. It can frequently be misdiagnosed and lead to significant impact on quality of life, particularly in patients with skin of color. Herein, we present an skin of color patient with this condition who experienced severe pruritus over years before receiving a definitive diagnosis. Clobetasol improved her condition and quality of life over several months.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liquefactive subcutaneous fat necrosis of the newborn. 新生儿液化性皮下脂肪坏死。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664694
Negar Esfandiari, Hannah J Porter, Keith Morley
{"title":"Liquefactive subcutaneous fat necrosis of the newborn.","authors":"Negar Esfandiari, Hannah J Porter, Keith Morley","doi":"10.5070/D330664694","DOIUrl":"https://doi.org/10.5070/D330664694","url":null,"abstract":"<p><p>Subcutaneous fat necrosis of the newborn is a disease affecting neonates in the first weeks to months of life. It is characterized by dermal edema and underlying fat necrosis, typically presenting with firm, erythematous subcutaneous plaques and nodules, often located on the shoulders, back, buttocks, thighs, and extremities. We report an unusual presentation of liquefactive subcutaneous fat necrosis of the newborn in a two-week old term infant. The neonatal period was complicated by respiratory failure requiring intubation and severe encephalopathy. After completion of therapeutic hypothermia, the patient developed fluctuant and liquefactive nodules on her back. The neonate also had initial hypocalcemia that required treatment and then developed hypercalcemia, that resolved without intervention. The nodules and plaques on her back persisted into the first year of life and then gradually started to improve when she was 13 months old.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deoxycholic acid injections as a nonsurgical treatment for lipomas in adiposis dolorosa (Dercum disease). 去氧胆酸注射作为非手术治疗多脂性脂肪瘤。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664693
Ziv Schwartz, Kayla Brockmeyer, Neda Nikbakht
{"title":"Deoxycholic acid injections as a nonsurgical treatment for lipomas in adiposis dolorosa (Dercum disease).","authors":"Ziv Schwartz, Kayla Brockmeyer, Neda Nikbakht","doi":"10.5070/D330664693","DOIUrl":"https://doi.org/10.5070/D330664693","url":null,"abstract":"<p><p>Adiposis dolorosa (Dercum disease) is a rare condition characterized by diffuse and recurring painful lipomas on the trunk and extremities. Patients are typically middle-aged females with an elevated BMI presenting with chronic pain. Physical examination reveals soft subcutaneous nodules and masses, tender to palpation. The associated pain significantly impacts quality of life and requires therapeutic intervention. The most common treatment option is surgical excision. Alternative options should be considered for patients with numerous lipomas where surgical management is not practical or is not desired. Deoxycholic acid injections are a viable alternative non-surgical technique. We present a case of a 55-year-old woman who presented with a history of Dercum disease and worsening pain associated with multiple lipomas. The patient desired a non-surgical intervention. She was subsequently treated with three rounds of deoxycholic acid injections with reduction in pain and improved mobility. Intralesional deoxycholic acid injections are a safe and effective nonsurgical alternative for patients with multiple lipomas.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Severe disseminated paracoccidioidomycosis. 严重播散性副球孢子菌病。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664692
Ezequias B Martins, Halber Fm Alves, Remberto Mc Vilte, Luciana Pantaleao, Isadora Ocp Da Silva, Natalia Cz Silva, Laura C Ferreira, Karla Rom Ronchini, Thais O Vieira, Maria Vitoria M, Veronica Rb Leite, Patricia Yvonne M
{"title":"Severe disseminated paracoccidioidomycosis.","authors":"Ezequias B Martins, Halber Fm Alves, Remberto Mc Vilte, Luciana Pantaleao, Isadora Ocp Da Silva, Natalia Cz Silva, Laura C Ferreira, Karla Rom Ronchini, Thais O Vieira, Maria Vitoria M, Veronica Rb Leite, Patricia Yvonne M","doi":"10.5070/D330664692","DOIUrl":"https://doi.org/10.5070/D330664692","url":null,"abstract":"<p><p>Paracoccidioidomycosis is a systemic fungal disease with a highly variable distribution, endemic to Central and South America with the highest prevalence in Brazil, Argentina, and Colombia. The chronic presentation of the disease is commonly observed in adult men and they manifest with pulmonary and mucocutaneous lesions. We report a fatal case of disseminated paracoccidioidomycosis in a 68-year-old immunocompetent man, with pulmonary, skin, mucosal, and cerebral involvement. Mucocutaneous lesions were decisive for the etiological diagnosis.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wolf isotopic response: immunotherapy-related lichenoid eruption localizing to prior radiation site. 狼同位素反应：免疫治疗相关的地衣样疹定位于先前的放射部位。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664696
Alexander J Jafari, Drew Kuraitis
{"title":"Wolf isotopic response: immunotherapy-related lichenoid eruption localizing to prior radiation site.","authors":"Alexander J Jafari, Drew Kuraitis","doi":"10.5070/D330664696","DOIUrl":"10.5070/D330664696","url":null,"abstract":"<p><p>Wolf isotopic response refers to a new skin disorder manifesting in the area of a previous skin lesion that has healed. A variety of disease processes and dermatoses have been described that evoke an isotopic response. We report a man with metastatic hepatocellular carcinoma who received palliative radiation and later experienced a pembrolizumab-induced lichenoid dermatitis at the same site of radiation, representing a cutaneous immune-related adverse event displaying an isotopic response.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug-induced subacute cutaneous lupus erythematous from cenobamate: case presentation and review of the literature. 药物致亚急性皮肤红斑狼疮：病例报告及文献复习。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664689
Safiyyah A Bhatti, Daniel Joffe, Timothy Webster, Jason B Lee
{"title":"Drug-induced subacute cutaneous lupus erythematous from cenobamate: case presentation and review of the literature.","authors":"Safiyyah A Bhatti, Daniel Joffe, Timothy Webster, Jason B Lee","doi":"10.5070/D330664689","DOIUrl":"https://doi.org/10.5070/D330664689","url":null,"abstract":"<p><p>A 68-year-old woman with a history of seizures on cenobamate presented with an itchy rash all over her body. The rash started about one month prior to her presentation to the dermatology clinic. The rash was initially treated with topical triamcinolone with improvement at one-month follow-up. However, four months later the rash flared and there was concern that cenobamate was the cause. Biopsy was performed showing vacuolar interface dermatitis with atrophy, suggestive of subacute lupus erythematosus. Blood work revealed positive antinuclear antibody, anti-ribonucleoprotein antibody, Sjogren Anti-SS-A and positive histone antibody. Given the worsening rash, positive labs, and cenobamate as the only changed drug several months before initial onset, she was diagnosed with drug-induced subacute cutaneous lupus erythematous and her cenobamate was discontinued. To the best of your knowledge, this is the first reported case of a medication in the carbamate family leading to drug induced subacute cutaneous lupus erythematosus.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subungual chondroma in a teenager. 青少年的趾骨下软骨瘤。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664698
M Voloshynovych, T Boichuk, O Berezkin, G Girnyk, N Matkovska, I Berezkina
{"title":"Subungual chondroma in a teenager.","authors":"M Voloshynovych, T Boichuk, O Berezkin, G Girnyk, N Matkovska, I Berezkina","doi":"10.5070/D330664698","DOIUrl":"https://doi.org/10.5070/D330664698","url":null,"abstract":"<p><p>Soft tissue chondroma is a rare benign tumor that occurs more often in the distal limbs and is unattached to the underlying bone. An 11-year-old boy, presented with a nodule of the subungual area of the right big toe. Objectively, the nail plate was partially destroyed owing to protrusion. Digital dermoscopy revealed yellow keratinous masses in the subungual area, with fibers adhering to the surface. Post-traumatic hemorrhages were observed in the tumor. Owing to functional discomfort, the patient underwent removal of the mass under local anesthesia. The histological picture is consistent with subungual soft tissue chondroma. Subungual soft tissue chondroma is more common in adults, but can affect people of all ages.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The most powerful topical anti-inflammatory: the cautionary and enlightening story of SKIN-CAP. 最强大的局部消炎：皮肤帽的警示和启发的故事。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664682
Carlton T Faulk, Mark R Pittelkow, Steven R Feldman, David L Swanson
{"title":"The most powerful topical anti-inflammatory: the cautionary and enlightening story of SKIN-CAP.","authors":"Carlton T Faulk, Mark R Pittelkow, Steven R Feldman, David L Swanson","doi":"10.5070/D330664682","DOIUrl":"https://doi.org/10.5070/D330664682","url":null,"abstract":"<p><p>Topical treatment with glucocorticosteroids is a mainstay therapy for many dermatologic conditions. Though efficacious in many, topical therapies often fail to achieve desired positive results in clinical practice. SKIN-CAP spray (Cheminova Laboratories International SA, Madrid, Spain), a product containing activated zinc pyrithione, and subsequently found to have contained clobetasol, provided unprecedented clearing of psoriasis even when ultra-high potency topical glucocorticosteroids had failed. A PubMed for terms related to corticosteroids, topical therapy, patient adherence, and SKIN-CAP spray was performed. Articles from 1997 to 2023 were included in the review of SKIN-CAP spray. In this review, we report the background of SKIN-CAP as well as studies that were performed in an attempt to explain its perceived high efficacy. The remarkable efficacy that occurred with SKIN-CAP over other delivery systems for high potency topical corticosteroids was initially speculated to be a consequence of an interaction between the zinc pyrithione and the clobetasol. However, no synergistic efficacy was identified, and there was no greater drug delivery. Better adherence to the SKIN-CAP product may explain the efficacy. The SKIN-CAP story provides insights into the need for healthy skepticism, the importance of treatment adherence, and ways to encourage better adherence to topical medications.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical cantharidin use in dermatology: an updated review. 局部斑蝥素在皮肤病学中的应用：最新综述。
Dermatology online journal Pub Date : 2024-12-15 DOI: 10.5070/D330664680
Helana Ghali, Logan R Smith, Amanda Krenitsky, Alexia M Joseph, David Aung-Din, Kerry Hennessy, Sarah Moore, James M Grichnik
{"title":"Topical cantharidin use in dermatology: an updated review.","authors":"Helana Ghali, Logan R Smith, Amanda Krenitsky, Alexia M Joseph, David Aung-Din, Kerry Hennessy, Sarah Moore, James M Grichnik","doi":"10.5070/D330664680","DOIUrl":"https://doi.org/10.5070/D330664680","url":null,"abstract":"<p><p>Cantharidin, a natural toxin produced by the blister beetle, is a topical agent that induces acantholysis of the epidermis, breaking down desmosome plaques through the release of serine proteases. Cantharidin is available in three liquid forms: Ycanth (0.7%), Canthacur (0.7%), and Canthacur PS (1% cantharidin, 30% salicylic acid, 2% podophyllotoxin). Ycanth is used to treat molluscum contagiosum (MC). Canthacur is routinely used to treat a variety of dermatologic conditions including MC, plantar warts, and common warts, whereas Canthacur PS is a more potent formulation indicated for treatment of plantar warts only. The objective of this review is to highlight the efficacy, safety, and diverse use of topical cantharidin in the treatment of various skin conditions. Conditions in which treatment with topical cantharidin yielded a good-to-excellent response include MC, plantar warts, and common warts. Topical cantharidin treatment of anogenital warts yielded mixed results. None of the indications reviewed herein yielded a poor response to topical cantharidin. Overall, topical cantharidin resulted in a good-to-excellent clinical response in several conditions with mild and transient adverse events. The results of this review suggest the safe and efficacious use of topical cantharidin in the field of dermatology and highlight the potential for future use.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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