发布求助
文献互助 智能选刊 最新文献

Current Opinion in Neurobiology最新文献

筛选
英文 中文
Interoception 2025 Interoception 2025。
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-09-30 DOI: 10.1016/j.conb.2025.103122
Zachary A. Knight, Stephen D. Liberles
{"title":"Interoception 2025","authors":"Zachary A. Knight, Stephen D. Liberles","doi":"10.1016/j.conb.2025.103122","DOIUrl":"10.1016/j.conb.2025.103122","url":null,"abstract":"","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"95 ","pages":"Article 103122"},"PeriodicalIF":5.2,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural basis for parental behavioral transitions in mice 小鼠亲代行为转变的神经基础。
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-09-18 DOI: 10.1016/j.conb.2025.103113
Kazunari Miyamichi
{"title":"Neural basis for parental behavioral transitions in mice","authors":"Kazunari Miyamichi","doi":"10.1016/j.conb.2025.103113","DOIUrl":"10.1016/j.conb.2025.103113","url":null,"abstract":"<div><div>Parental care is fundamental to the physical and mental well-being of mammalian offspring. Females undergo pregnancy, parturition, and lactation, with hormones pivotal to these processes—such as estrogen, prolactin, and oxytocin—also playing essential roles in mediating infant-directed caregiving behaviors. Although the extent of paternal involvement varies widely across species, the same hormones that regulate maternal transitions may be utilized to facilitate paternal behavioral adaptations. Recent advances in single-cell transcriptomics and cell-type-specific genetic manipulations have elucidated the mechanisms through which hormones interact with discrete cell types to drive structural and physiological plasticity within key regions of the brain governing parental behaviors. Furthermore, parental care serves as a valuable model for studying naturally occurring motivated behavioral learning, wherein higher-order cognitive regions and monoaminergic systems play an integrative role. This review highlights recent progress in this field, with a brief discussion on the potential sexually dimorphic engagement of specific hormonal systems.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"95 ","pages":"Article 103113"},"PeriodicalIF":5.2,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formation of sensory maps: New tools reveal novel insights into neural development 感官地图的形成：新工具揭示了神经发育的新见解
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-09-15 DOI: 10.1016/j.conb.2025.103112
Nova Qi , Abby Wood , Wesley B. Grueber
{"title":"Formation of sensory maps: New tools reveal novel insights into neural development","authors":"Nova Qi ,&nbsp;Abby Wood ,&nbsp;Wesley B. Grueber","doi":"10.1016/j.conb.2025.103112","DOIUrl":"10.1016/j.conb.2025.103112","url":null,"abstract":"<div><div>The development of functional neural circuits depends on the navigation of neurites (axons and dendrites) through spatially complex and molecularly diverse environments to their appropriate targets. How these processes maneuver through dense surroundings to reach their targets is a long-standing question in neuroscience. Studies of sensory systems have been especially enlightening for identifying cues that underlie connectivity due to their organization as stereotyped neural maps. Recent advances in imaging, connectomics, and genomics have profoundly deepened our understanding of these processes and uncovered new mechanisms regulating circuit development. In this review, we discuss studies of <em>Drosophila</em> sensory systems that provide new insights into axon and dendritic targeting, partner identification and selection, and subcellular refinement. We highlight related or divergent findings in other systems and provide an outlook for future studies.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"95 ","pages":"Article 103112"},"PeriodicalIF":5.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145061348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural plasticity supporting parental behaviors 支持父母行为的神经可塑性
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-09-13 DOI: 10.1016/j.conb.2025.103111
Patrick T. O'Neill , Dayu Lin
{"title":"Neural plasticity supporting parental behaviors","authors":"Patrick T. O'Neill ,&nbsp;Dayu Lin","doi":"10.1016/j.conb.2025.103111","DOIUrl":"10.1016/j.conb.2025.103111","url":null,"abstract":"<div><div>Becoming a parent involves extraordinary changes that allow caregivers to attend to and nurture infants. Neural circuits must adapt to the demands of caregiving to orchestrate various complex nurturing behaviors. These changes occur between two opposing circuits: a circuit primed for the expression of parenting to execute caregiving, and a circuit that suppresses this behavioral expression when the timing is not appropriate. In this review, we provide an overview of the neural circuits supporting the positive and negative control of parental behaviors and discuss mechanisms by which these opposing circuits are altered to facilitate the onset of parental care.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"95 ","pages":"Article 103111"},"PeriodicalIF":5.2,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Activity-dependent splicing: A game changer for proteome remodeling in the brain 活动依赖剪接：大脑中蛋白质组重塑的游戏规则改变者
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-09-10 DOI: 10.1016/j.conb.2025.103110
Oriane Mauger
{"title":"Activity-dependent splicing: A game changer for proteome remodeling in the brain","authors":"Oriane Mauger","doi":"10.1016/j.conb.2025.103110","DOIUrl":"10.1016/j.conb.2025.103110","url":null,"abstract":"<div><div>The brain’s intricate neuronal circuits are continuously refined by external and internal stimuli throughout life. These plasticity events rely on a major proteome remodeling. Activity-dependent splicing has an unparalleled potential to instruct this proteome remodeling, enabling precise spatial and temporal control. This review examines recent progress in understanding activity-dependent splicing and highlights promising areas for future research into its role in brain plasticity.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"95 ","pages":"Article 103110"},"PeriodicalIF":5.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145027587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Statistical learning and representational drift: A dynamic substrate for memories 统计学习和表征漂移：记忆的动态基础
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-09-02 DOI: 10.1016/j.conb.2025.103107
Jens-Bastian Eppler , Matthias Kaschube , Simon Rumpel
{"title":"Statistical learning and representational drift: A dynamic substrate for memories","authors":"Jens-Bastian Eppler ,&nbsp;Matthias Kaschube ,&nbsp;Simon Rumpel","doi":"10.1016/j.conb.2025.103107","DOIUrl":"10.1016/j.conb.2025.103107","url":null,"abstract":"<div><div>In many brain areas, neurons exhibit continuous changes in their tuning properties over days, even when supporting stable percepts and behaviors–a phenomenon termed representational drift. How do neuronal circuits maintain stable function when their constituent elements are in constant flux? Here, we review recent theoretical and experimental work on interconnected levels, ranging from perpetual changes in synapses driving drifts in tuning of individual neurons to emergent stability at the population level, preserving similarities of activity patterns associated to specific percepts or behaviors. We propose that statistical learning, beyond its well-established roles during development and adaptation to new contexts, is also essential under steady behavioral and environmental conditions to safeguard the stability of representational similarities. We discuss implications for learning, memory, and forgetting. This framework reconciles the apparent paradox between unstable neural activity and stable perception, suggesting that representations are maintained through dynamic processes rather than static neural codes.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"94 ","pages":"Article 103107"},"PeriodicalIF":5.2,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central regulation of cardio-behavioral responses: Circuit engagement during aversive emotional states 心脏行为反应的中枢调节：厌恶情绪状态下的回路参与
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-08-28 DOI: 10.1016/j.conb.2025.103105
Silvia Rodriguez-Rozada , Philip Tovote
{"title":"Central regulation of cardio-behavioral responses: Circuit engagement during aversive emotional states","authors":"Silvia Rodriguez-Rozada ,&nbsp;Philip Tovote","doi":"10.1016/j.conb.2025.103105","DOIUrl":"10.1016/j.conb.2025.103105","url":null,"abstract":"<div><div>Dynamic cardiovascular control supports adaptive behavior under external and internal influences. Higher-order brain regions regulate stress-related cardiovascular changes via their influence on medullary nuclei, which control autonomic reflexes. Despite extensive research, the precise neural circuits linking cardiac function and behavior under emotional stress remain unclear. This review highlights recent studies identifying specific cell types and pathways involved in cardiovascular regulation, emphasizing their dynamical role under baseline and threat conditions. Cardiovascular responses are closely tied to behavior through descending brain-to-heart command pathways and ascending interoceptive feedback. Our framework for characterizing cardio-behavioral states under threat identifies rapid-acting “microstates” and slow-changing “macrostates” reflecting context- and time-dependent threat levels. Multidimensional measurements and integrated analytical approaches are required to study neural circuits controlling cardio-behavioral states. Understanding the homeodynamic regulation of cardiac function and its behavioral links is essential for unraveling brain-heart interactions.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"94 ","pages":"Article 103105"},"PeriodicalIF":5.2,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial overview: Introduction to neurobiology of learning and plasticity 编辑概述：学习和可塑性神经生物学导论
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-08-27 DOI: 10.1016/j.conb.2025.103098
Jason Shepherd, Hey-Kyoung Lee
{"title":"Editorial overview: Introduction to neurobiology of learning and plasticity","authors":"Jason Shepherd,&nbsp;Hey-Kyoung Lee","doi":"10.1016/j.conb.2025.103098","DOIUrl":"10.1016/j.conb.2025.103098","url":null,"abstract":"","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"94 ","pages":"Article 103098"},"PeriodicalIF":5.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144908292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging theory and experiment in (statistical) learning （统计）学习理论与实验的桥梁
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-08-27 DOI: 10.1016/j.conb.2025.103106
Tara Keck
{"title":"Bridging theory and experiment in (statistical) learning","authors":"Tara Keck","doi":"10.1016/j.conb.2025.103106","DOIUrl":"10.1016/j.conb.2025.103106","url":null,"abstract":"<div><div>Statistical learning and neuroplasticity have been studied extensively over the past decades by theorists and experimentalists working in animal and human experimental models, with neurobiologists, cognitive neuroscientists, and theorists each offering complementary inputs to the field. While there are collaborations between theorists and each of experimentalists working in animal and human models, there are more limited interactions across the experimental groups, with these fields remaining largely siloed. Here, we discuss the challenges for cross-disciplinary collaboration, as well as offer suggestions for ways to facilitate it in the future. We propose that theorists are in a key position to facilitate interactions between experimentalists working in animal and human models by developing theories or working models that span these two fields to enable cross-disciplinary collaboration. Increasing training for early career researchers to become skilled cross-disciplinary collaborators may also help facilitate future interactions in these fields.</div></div>","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"94 ","pages":"Article 103106"},"PeriodicalIF":5.2,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144903004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developmental Neuroscience in the 21st Century 21世纪的发育神经科学
IF 5.2 2区 医学
Current Opinion in Neurobiology Pub Date : 2025-08-25 DOI: 10.1016/j.conb.2025.103091
Lisa Goodrich, Song-Hai Shi
{"title":"Developmental Neuroscience in the 21st Century","authors":"Lisa Goodrich,&nbsp;Song-Hai Shi","doi":"10.1016/j.conb.2025.103091","DOIUrl":"10.1016/j.conb.2025.103091","url":null,"abstract":"","PeriodicalId":10999,"journal":{"name":"Current Opinion in Neurobiology","volume":"94 ","pages":"Article 103091"},"PeriodicalIF":5.2,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144893703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信