Journal of Diagnosis & Case Reports最新文献

{"title":"The Managerial and Organizational Impact of Therapeutic Adherence in the National Health System: A Regional Social Welfare Comparison in the Perspective of Planning PNRR Funding and Social Welfare Regulation","authors":"M. Agnello","doi":"10.47363/jdcrs/2021(2)122","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)122","url":null,"abstract":"This article analyses therapeutic adherence to the national health system from a multidimensional perspective, through a comparative analysis of regulation and planning at different levels of European, national, regional and corporate governance. This analytical path is oriented to identify the critical issues and possible strategies aimed not only to overcome them, but also to implement the current management through organizational tools and alternative management models. In this evolution, an important role is played by the funding deriving from the PNRR intended to implement both territorial medicine and digital innovation, as main axes of the path to improving therapeutic adhesion. The conclusions concern the application of organizational models ( one health, change management, value based health) able to channel these resources towards this area of therapeutic adherence. In the current phase of planning and financing from PNRR mission 6, italian institutions such as AGENAS and the Ministry of Health have initiated the reform of the D.M. n. 70/2015 through outline the lines of development of social protection to support social assistance adherence therapeutic. This programming path is accompanied by the regulation of local health care characterized by a greater continuity of care between hospital and home and multidisciplinary coordination for a wider take-up.","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130115387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesenteric Cyst in a 5-Year-Old Child with Partial abdominal Obstruction: Case Report from Bahrain","authors":"M. Hammad","doi":"10.47363/jdcrs/2021(2)124","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)124","url":null,"abstract":"Mesenteric cysts are rare, variably-sized intra-abdominal lesions developing during childhood. Their symptoms vary from being asymptomatic and incidentally found to non-specific, presenting as lower abdominal pain, nausea and vomiting, constipation and diarrhea. Clinically, these abdominal masses may be palpable in more than 50% of patients. The diagnosis of these lesions can be made accurately radiologically through abdominal ultrasound and CT. The treatment of choice is complete surgical resection. Hereby we report the clinical course of a 5 year old child with a mesenteric cyst who complained of acute abdominal pain, constipation and vomiting and were surgically treated after being diagnosed with a mesenteric cyst based on radiological examination.","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125512202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical Therapy of Skin Scabs in Psoriasis with Salicylic Acid: Case Report","authors":"Wilfredo Molina Wills, V. Rodriguez","doi":"10.47363/jdcrs/2021(2)123","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)123","url":null,"abstract":"The objective was to evaluate the keratolytic and anti-inflammatory action of salicylic acid in the affected area in the case reported. Methods. Clinical photography a digital camera was used Olympus SP570UZ with master software 2.0. The images obtained both in the initial phase without treatment and at the 72 hours of treatment were transferred and stored on a 4-core Sansung computer. The auto-dial adjustment option was selected. In this way, the camera selects the optimal way to take the photo shot. Analysis of the affected skin with scabs. Image J software was used to measure the area selected for the study in both cases. This measurement was made in pixels for the photographic region under study. Results. The image j software program measures the areas in pixels, to decrease in measurement error there was no calibration. That is, the measurement of the areas in pixels was maintained. The percentage ratios of the affected or non-affected areas for both left and right legs are presented in Tables. It is possible to observe the reduction of the affected area. The doubtful areas represent for the left leg 5.21% and for the right leg 30.08% after treatment. Only a clearly visible area with crusts and scabs of 1.60% was observed after treatment.","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"485 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122178612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Waist-to-Hip Ratio on Health and Fertility in Humans","authors":"PD Gupta, K. Pushkala","doi":"10.47363/jdcrs/2021(2)119","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)119","url":null,"abstract":"Ancel Keys gave the formula devised in the 1840's a new name, Waist to Hip Ratio (WHR) in the early 70’s. Since then it has become an important parameter for measurement of health. The Waist-to-Hip Ratio (WHR) gives more meaningful information rather than Body Mass Index (BMI). Here we have described the applications of WHR in prediction of certain diseases due to change in WHR values. If both males and females do not maintain proper WHR values, they suffer with many health problems.","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124156135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BCRP Expression with Lipofuscin Accumulation in Abnormal Neurons from a Child with Transmantle Cortical Dysplasia (TMCD) and Refractory Epilepsy","authors":"C. L., Lubieniecki F","doi":"10.47363/jdcrs/2021(2)118","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)118","url":null,"abstract":"Cerebral cortical development’s malformations, including the transmantel cortical dysplasia (TMCD), have been associated with refractory epilepsy (RE). Several ABC-transporters as “P-glycoprotein (P-gp), Multidrug resistance proteins (MRP-1) and breast Cancer Resistant Protein (BCRP)” are up-regulated in human epileptogenic brain lesions of RE, however they have not been explored in Transmantle cortical dysplasia (TMCD). We describe a 13 years old boy with Refractory Epilepsy (RE) and abnormal Magneic Resonance Image (MRI) (T1, FLAIR and T2) compatible with TMCD. Clinical follow-up, images and pathologic studies were developed by routinely methods. Epilepsy surgical treatment included total lesion resection with complete seizures remission at date. Deeper brain areas related with images findings, showed features of TMCD with abnormal ballooned neurons with high accumulation of PAS+, sudanophilic and autoflourescent lipopigment (LP). Immunohistochemistry, using primary monoclonal antibodies for P-gp, MVP and BCRP proteins, showed high expression of BCRP in several ballooned-LP+ cells. In contrast, P-gp and MVP were negative and MRP-1 has not been investigated. The links of BCRP with LP and AEDs are not known, however, the expression of BCRP in these LP+ ballooned neurons from the epileptogenic brain area, with P-gp/MVP negative results, suggest that BCRP could be associated to refractory epileptic phenotype.","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130281764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing Your Screen Time","authors":"Gurmeet Singh Sarla","doi":"10.47363/jdcrs/2021(2)121","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)121","url":null,"abstract":"The screen as a computer, mobile phone, tablet or television is a piece of present day life. Expanded screen time is related with heftiness, pernicious impacts on temperament and subjective and socio-enthusiastic advancement, prompting poor instructive execution in kids and thus ought to be diminished to 1-2 hours per day. Drawn out TV seeing brings down psychological capacities, particularly identified with momentary memory, early reading and math aptitudes and language development. Gaming animates outrage, viciousness, weight, epilepsy and social segregation in kids and teenagers. Enjoying over the top on line shopping is a type of web enslavement and has been named as Pathological purchasing and has a hidden patho-physiology of delight chasing or departure of negative feelings and intellectual instruments like impulsivity, disappointment in self-guideline, or basic leadership deficiencies. Extreme utilization of social networking sites like Facebook and texting Apps like WhatsApp has prompted compulsion causing well-being impacts as headache, low backache, obesity, burning eyes, insomnia, exhaustion, lowers self-esteem and causes depression. This review article examined the different well-being impacts of the expanding screen time in the cutting edge time and prescribes screen time to be constrained to 1-2 hours in a day and a break from the 'screen' during weekends and family travels","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123330294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Identification of Dermatophytes from Environmental Specimens Comparing with Species Isolated from Clinical Specimens of Scalp Infection among Sudanese Basic School, Kosti, White Nile State, Sudan -2020","authors":"Yousif Mousa Alobaid Ahmed","doi":"10.47363/jdcrs/2021(2)120","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)120","url":null,"abstract":"Background: Tinea capitis (TC) or scalp ringworm is common in pediatric population with reported rates of infection ranging from 4% to 15 % .T.rubrum is rarely reported in countries with a temperate climate . There is always hair loss with varying degrees of scaling and erythema [1-3]. Objectives: To identify the role of soil, plant & sewage in transmission of ringworm of scalp infection. This study was carried out on Kosti basic school students who suffering from ringworm of scalp (fungal infection) in White Nile state at Sudan in 2020. Methodology, Data Analyses and Results: Due to preservation of this fungal infection among school children in Kosti basic school students, a total of fifty specimens collected from different sources to determine the source of this infection in the area of study, twenty five students who suffering from ring worm of scalp and twenty five from soil, sewage, water and trees in the period between January – December -2020.The samples collected by scraping the scalp by surgical blade and removing the hair with needle and forceps from the peripheral lesion and gathered in filter paper and closed tightly,10% KOH was used to clarify and keratinized tissues. Trees samples were collected by washing the tree’s leaves and with all soil, sewage, water were collected into container. All samples were cultured on sabouroad dextrose agar medium for one week at room temperature. After growth, lactophenol cotton blue staining was used to identify depending on the colonial morphology under microscope and tolook for color, septate, aseptate hyphae, macro, micro conidia and spores. The results showed that there was 68% of isolates from soil, sewage, water and trees were matched to scalp isolates. The soil is significant one of these when Chi-square (X2) was used (P value = 0.027) that means, the source of infection among students may be due to soil transmission. Conclusion and Recommendation: Our results highlight the epidemiology of fungal infection of Kosti basic school students. Further studies are necessary to verify these findings considering the relatively high rate of fungal infection to cover all expected area with similar observation.","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124438610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic Retinopathy","authors":"Eduardo Zans MD","doi":"10.47363/jdcrs/2021(2)116","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)116","url":null,"abstract":"","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122991980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Left Atrium and Atrial Fibrillation in Rheumatic Heart Disease Patient with Normally Functioning Mitral Valve Prosthesis","authors":"R. Walia, U. Chauhan","doi":"10.47363/jdcrs/2021(2)117","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)117","url":null,"abstract":"","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"178 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115180019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic and Risk Stratification Molecular Markers of Prostate Cancer Beyond PSA","authors":"F. Pinto, M. Ragonese","doi":"10.47363/jdcrs/2021(2)115","DOIUrl":"https://doi.org/10.47363/jdcrs/2021(2)115","url":null,"abstract":"Prostate cancer still represents the most common urinary malignancies and the second most common cancer in adult men after skin cancer. Prostate specific antigen (PSA) represents a milestone in the diagnosis and screening of prostate cancer since its introduction even considering its limitations in term of sensitivity and specificity. The widespread use of PSA often led to unnecessary biopsies and to the diagnosis of indolent cancers that do not require treatment, therefore in the era of tailored personalized medicine there is a strong need for new markers that overcome PSA and that can help to identify the patients that have clinically significant disease that must be treated. To date different urinary and serum biomarkers have been proposed in the diagnostic setting with promising results in terms of sensitivity and specificity, however, none of them have been routinely introduced in clinical practice. In this review we reported the latest evidence for prostate cancer diagnosis in terms of urinary and blood biomarkers. Considering all the available markers, it is highly unlikely that one single assay could fit all the requirements and it seems appropriate to use the combination of different urinary and serum markers together with clinical parameters in order to guarantee a good diagnostic performance and to identify only clinically significant disease","PeriodicalId":109633,"journal":{"name":"Journal of Diagnosis & Case Reports","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116542513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}