Current Nutrition & Food Science最新文献

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A Comprehensive Review on Therapeutic Potentials of Natural Cyclic Peptides 天然环肽的治疗潜力综述
IF 0.9
Current Nutrition & Food Science Pub Date : 2022-01-14 DOI: 10.2174/1573401318666220114153509
Renu Saharan, Suresh Kumar, S. Khokra, Sunil Singh, A. Tiwari, V. Tiwari, B. Sahoo, Manish Kumar
{"title":"A Comprehensive Review on Therapeutic Potentials of Natural Cyclic Peptides","authors":"Renu Saharan, Suresh Kumar, S. Khokra, Sunil Singh, A. Tiwari, V. Tiwari, B. Sahoo, Manish Kumar","doi":"10.2174/1573401318666220114153509","DOIUrl":"https://doi.org/10.2174/1573401318666220114153509","url":null,"abstract":"\u0000\u0000Cyclic peptides have emerged as a promising class of organic compounds that possess polypeptide chains with a cyclic ring structure. There is a circular sequence of bonds in which the ring structure is formed via linkage between one end of the peptide bond and the other end with an amide bond or any other chemically stable bonds like ether, thioether, lactone, and disulfide. Generally, the cyclic peptides are isolated from natural resources like invertebrate animals, micro-organisms of marine habitats, and higher plants. These cyclic peptides possess unique structures with diverse pharmacological activities. Now a day, cyclic peptides possess superior therapeutic value due to several reasons such as greater resistance to enzymatic degradation (in vivo) and higher bio-availability. Some of these cyclic peptides are rich in leucine, proline while some have other amino acids as their major constituents. Numerous novel cyclic peptides isolated from natural sources are successfully developed as bioactive products. Recently, cyclic peptides derived from natural resources have attracted attention for exploring their numerous beneficial effects. Moreover, it is reported that natural cyclic peptides exhibit various therapeutic activities like an anthelmintic, ACE inhibitor, anti-tumor, microtubule inhibitor, anti-fungal, anti-malarial, and platelet aggregation inhibiting activity. In this review, various cyclic peptides are reported with structures and biological activities that are isolated from various natural sources. The natural cyclic peptides possess a wide spectrum of biological activities and can become a drug of the future for replacing the existing drugs which develop resistance\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47025909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Review on Acrylamide: A Hidden Hazard in Fried Carbohydrate-Rich Food 丙烯酰胺:油炸富含碳水化合物食品中的隐患
IF 0.9
Current Nutrition & Food Science Pub Date : 2022-01-04 DOI: 10.2174/1573401318666220104124753
Aditya Manivannan Iyer, Vedika Dadlani, H. Pawar
{"title":"Review on Acrylamide: A Hidden Hazard in \u0000Fried Carbohydrate-Rich Food","authors":"Aditya Manivannan Iyer, Vedika Dadlani, H. Pawar","doi":"10.2174/1573401318666220104124753","DOIUrl":"https://doi.org/10.2174/1573401318666220104124753","url":null,"abstract":"\u0000\u0000Acrylamide is classified as a hazard whose formation in carbohydrate-rich food cooked at a high temperature has created much interest in the scientific community. The review attempts to comprehend the chemistry and mechanisms of formation of acrylamide and its levels in popular foods. A detailed study of the toxicokinetic and biochemistry, carcinogenicity, neurotoxicity, genotoxicity, interaction with biomolecules, and its effects on reproductive health has been presented. The review outlines the various novel and low-cost conventional as well as newer analytical techniques for the detection of acrylamide in foods with the maximum permissible limits. Various effective approaches that can be undertaken in industries and households for the mitigation of levels of acrylamide in foods have also been discussed. This review will assist to provide in depth understanding about acrylamide that will make it simpler to assess the risk to human health from the consumption of foods containing low amounts of acrylamide.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45904549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protecting Superfood Olive Crop from Pests and Pathogen Using Image Processing Techniques: A Review 利用图像处理技术保护超级食品橄榄作物免受害虫和病原体的侵害
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-12-27 DOI: 10.2174/1573401318666211227103001
S. Sisodiya, A. Sinha, M. Debnath, R. Shekhawat, Surinder Singh Skehkawat
{"title":"Protecting Superfood Olive Crop from Pests and Pathogen Using Image Processing Techniques: A Review","authors":"S. Sisodiya, A. Sinha, M. Debnath, R. Shekhawat, Surinder Singh Skehkawat","doi":"10.2174/1573401318666211227103001","DOIUrl":"https://doi.org/10.2174/1573401318666211227103001","url":null,"abstract":"\u0000\u0000Olive (Oleo europaea L.) cultivars are widely cultivated all over the world. But it is often attacked by pests and pathogens. This deteriorates the quality of the crop leading to less yield of olive oil. Image processing techniques can be used to classify the different pathogens causing similar disease symptoms on olive leaves\u0000\u0000\u0000\u0000With the rapid increase in the availability of data in the field of nutrigenomics, the olive has established itself as a superfood and a potential source of therapeutics. The objective of this review is to emphasize the early detection and classification of the disease using image processing techniques\u0000\u0000\u0000\u0000A systematic literature search using keywords, Olive oil, pest and pathogen of olives, metabolic profiling were done on PubMed, ScienceDirect and Google Scholar.\u0000\u0000\u0000\u0000Disease infection often led to huge losses and poor quality of olive oil yield. Early understanding of disease infestations can safeguard the olive plant and the olive oil yield\u0000\u0000\u0000\u0000Disease infection often led to huge losses and poor quality of olive oil yield. Early understanding of disease infestations can safeguard the olive plant and the olive oil yield\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42585783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Evaluation of Nutritional Value, Antioxidant Activity and Phenolic Content of Protium serratum Engl and Artocarpus chama Buch.-Ham, Wild Edible Fruits Available in Tripura, a North- Eastern State of India 锯齿木和石竹的营养价值、抗氧化活性和酚类含量评价。火腿,可食用的野生水果,产于印度东北部的特里普拉邦
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-12-21 DOI: 10.2174/1573401318666211221155620
S. Biswas, A. Bora, P. Mudoi, T. K. Misra, Subrata Das
{"title":"Evaluation of Nutritional Value, Antioxidant Activity and Phenolic Content of Protium serratum Engl and Artocarpus chama Buch.-Ham, Wild Edible Fruits Available in Tripura, a North- Eastern State of India","authors":"S. Biswas, A. Bora, P. Mudoi, T. K. Misra, Subrata Das","doi":"10.2174/1573401318666211221155620","DOIUrl":"https://doi.org/10.2174/1573401318666211221155620","url":null,"abstract":"\u0000\u0000Protium serratum Engl (Indian red peer) and Artocarpus chama Buch.-Ham (wild jackfruit) are typical wild edible fruits, which have a wide range of folk medicinal properties. \u0000\u0000\u0000\u0000\u0000Our present study deals with the exploration of nutritional value, antioxidant activity and total phenolic content present in Protium serratum Engl and Artocarpus chama Buch.-Ham fruits. \u0000\u0000\u0000\u0000\u0000 Soxhlet apparatus was used to extract crude samples. The quantitative analysis of the wild edible fruits was broadly done by proximate and ultimate analysis techniques. \u0000\u0000\u0000\u0000\u0000The results showed that the moisture contents in P. serratum and A. chama Buch. are 78.53% and 74.23%, respectively. The obtained ash (8.59%), fiber (3.17%), total sugar (5.495 mg/100g), and fat (0.66%) contents are high in P. serratum. Whereas, A. chama Buch. has high content of protein (0.52%). Vitamin C content has higher in P. serratum (550 mg/100g) than that of A. chama Buch. (350 mg/100g). The result shows that the Ca and Mg contents have higher in P. serratum compared to A. chama Buch. Indian red peer shows good antioxidant property and has high total phenolic content as compared to wild jackfruit and some commercial fruits. \u0000\u0000\u0000\u0000\u0000The study establishes that further investigation must be done to find out new products development, processing and preservation techniques so that two underutilized fruits can get into our regular dietary habits. By doing so, we can enrich the fruit basket of the country.\u0000\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44894864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Phycocyanin: A Natural Antioxidant to Combat Free Radicals 藻蓝蛋白:一种对抗自由基的天然抗氧化剂
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-12-21 DOI: 10.2174/1573401318666211221160338
D. Zhuang, D. Tang, K. Chew, T. Ling
{"title":"Phycocyanin: A Natural Antioxidant to Combat Free Radicals","authors":"D. Zhuang, D. Tang, K. Chew, T. Ling","doi":"10.2174/1573401318666211221160338","DOIUrl":"https://doi.org/10.2174/1573401318666211221160338","url":null,"abstract":"\u0000\u0000Various research showed that antioxidants can effectively overcome the damage caused by free radicals to the human health. Therefore, antioxidants are identified as one of the main directions in the development of health care and cosmetics products due to high demand in the market. This review mainly focuses on the phycocyanin, a type of natural antioxidant mainly found in cyanobacteria. This mini review summarizes the phycocyanin sources and numerous extraction methods of phycocyanin along with the analytical methods in determining its ability to suppress free radicals. Phycocyanin has been proven to play an important role in scavenging free radicals and enhancing the body’s antioxidant capacity. However, there are lack of long-term randomized clinical trial results that can be used as evidence in showing the benefits of phycocyanin. The existing phycocyanin extraction methods using solvents, ultrasonic-assisted, freeze-thaw and etc. can extract high-quality phycocyanin efficiently and quickly. Scientists are also trying to incorporate advanced technologies such as \"Industry 4.0\" to optimize and enhance the industrial production of phycocyanin. Lastly, this review also describes the difficulties faced during the phycocyanin production or extraction process and financial obstacles in order to achieve the popularization of phycocyanin.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49474059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Oilseed Cakes in the Food Industry: A Review on Applications, Challenges, and Future Perspectives 油籽饼在食品工业中的应用、挑战与展望
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-12-09 DOI: 10.2174/1573401317666211209150147
A. Abedini, A. Alizadeh, Aida Mahdavi, S. A. Golzan, Mahla Salimi, Behrouz Tajdar-oranj, H. Hosseini
{"title":"Oilseed Cakes in the Food Industry: A Review on Applications, Challenges, and Future Perspectives","authors":"A. Abedini, A. Alizadeh, Aida Mahdavi, S. A. Golzan, Mahla Salimi, Behrouz Tajdar-oranj, H. Hosseini","doi":"10.2174/1573401317666211209150147","DOIUrl":"https://doi.org/10.2174/1573401317666211209150147","url":null,"abstract":"\u0000\u0000By-products from the food sector now have a wide range of applications. Low-cost raw\u0000materials, followed by low-cost goods, are regarded as one of the sectors’ top goals. Because of its\u0000economic relevance, reduced price, and nutrients such as protein, fiber, carbs, and antioxidants,\u0000oilseed cakes (OCs) have found a desirable place in livestock and poultry feed. Furthermore, because the cake has the same desirable nutrients, its usage in the food business is unavoidable.\u0000However, its use in this sector is not simply for nutritious purposes and has it has different impacts\u0000on flavor, texture, color, and antioxidant qualities. Therefore, as a result of its desirable qualities,\u0000the cake can be more useful in extensive applications in the food business, as well as in the manufacture of supplements and novel foods. The current review looks at the reapplications of byproducts obtained from oilseeds (soybean, sunflower, sesame, canola, palm kernel, peanut, mustard, and almond) in the food sector in the future. Furthermore, allergenicity, toxicity, antinutritional compounds, and techniques of extracting cakes from oilseeds have been discussed.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":"1 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68170738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Is Sunflower Cooking Oil Desirable for Colorectal Cancer? In Vivo Studies on Azoxymethane-Induced Colon Cancer in Rats 向日葵食用油对大肠癌癌症好吗?甲氧基甲烷诱导大鼠癌症的体内研究
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-12-08 DOI: 10.2174/1573401317666211208144625
Sheba R. Nakka David, Miza Syazwina Mohammad, L. Y. Chee, Rajan Rajabalaya
{"title":"Is Sunflower Cooking Oil Desirable for Colorectal Cancer? In Vivo Studies on Azoxymethane-Induced Colon Cancer in Rats","authors":"Sheba R. Nakka David, Miza Syazwina Mohammad, L. Y. Chee, Rajan Rajabalaya","doi":"10.2174/1573401317666211208144625","DOIUrl":"https://doi.org/10.2174/1573401317666211208144625","url":null,"abstract":"\u0000\u0000The incorporation of oils in the diet may have promoting or inhibitory effects on Colorectal Cancer (CRC). In this study, azoxymethane (AOM) was used to mimic CRC in rats and the effect of sunflower oil on cancer progression in the colon of the rats was tested. \u0000\u0000\u0000\u0000\u0000This study was conducted to investigate the effect of sunflower oil on preneoplastic cancer properties on the colonic mucosal surface for tumors and the aberrant crypt foci (ACF). \u0000\u0000\u0000\u0000\u0000Six weeks old Sprague-Dawley male rats were randomized into 4 groups of 6 rats each, namely naïve, positive control, negative control and sunflower oil-fed. CRC was induced by AOM by subcutaneous injection of 20 mg/kg. After CRC induction, the rats were given respective treatment of either basal diet (naïve group), 10 mg/kg indomethacin (positive control), 0.9% saline (negative control), and 7% sunflower oil (experimental group) daily by oral gavage for 42 days. Rats were sacrificed by cervical dislocation; colon samples were visually observed for any tumors on the colonic mucosal surface and evaluated for ACF; histopathological examinations were also performed.\u0000\u0000\u0000\u0000\u0000 The mean body weights of the rats were similar in all groups as per one-way ANOVA. A total of 3 ACF were found in the negative group while none were observed in others. The crypts appeared regular with circular luminal openings and were arranged closely packed together in the naïve group. Crypts in the positive and treated group had a similar appearance like naïve group. \u0000\u0000\u0000\u0000\u0000 Sunflower oil inhibition of the preneoplastic cancer ACF properties were tested but were found to be insignificant when administered during CRC treatment or management. However long-term experiment with a greater number of days will yield better development of tumor and ACF development and will be useful identifying the molecular mechanism. \u0000\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41877376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Spices and Hypertension: An Insight for Researchers 香料与高血压:研究人员的见解
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-11-22 DOI: 10.2174/1573401317666211122144827
K. R. Nair, Arya V.S, Kanthlal S.K., U. P
{"title":"Spices and Hypertension: An Insight for Researchers","authors":"K. R. Nair, Arya V.S, Kanthlal S.K., U. P","doi":"10.2174/1573401317666211122144827","DOIUrl":"https://doi.org/10.2174/1573401317666211122144827","url":null,"abstract":"\u0000\u0000Hypertension is a global public health concern since it can lead to complications like stroke, heart disease and kidney failure. These complications can add to disability, increase healthcare costs and can even result in mortality. In spite of the availability of a large number of antihypertensive drugs, the control of blood pressure is suboptimal in many patients. Spices have been used as flavouring agent and to treat diseases in folk medicine since they are considered to be rich sources of phytochemicals especially polyphenols. Hence, during recent years there is renewed interest among researchers to explore natural sources, especially spices in an attempt to find cheaper alternatives with fewer side effects. Our aim is to review the relevant preclinical and clinical studies focused towards the potential use of spices in the management of hypertension. Studies conducted on the most common spices such as celery, cinnamon, cardamom, garlic, ginger, saffron, and turmeric, have been elaborated in this review. These spices may be lowering blood pressure via several possible mechanisms including antioxidant effect, increase in nitric oxide production, reduction in calcium ion concentration, modulation of renin angiotensin pathway etc.\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47586208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review on Methods Used to Determine Antioxidant Activity of Origanum majorana 牛头草抗氧化活性测定方法综述
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-11-10 DOI: 10.2174/1573401317666211110104812
G. Mohapatra, Bimala Tripathy, B. Kumar, B. Chowdhury, Rajaram Das
{"title":"Review on Methods Used to Determine Antioxidant Activity of Origanum majorana","authors":"G. Mohapatra, Bimala Tripathy, B. Kumar, B. Chowdhury, Rajaram Das","doi":"10.2174/1573401317666211110104812","DOIUrl":"https://doi.org/10.2174/1573401317666211110104812","url":null,"abstract":"\u0000\u0000Presence of free radicals in human body are harmful and cell systems are induce many diseases like cardiovascular, diabetes, cancer, inflammation, neuro-degenerative disorder, atherosclerosis, cataract, etc. Antioxidants can balance the effect of free radicals. Antioxidant-rich herbs are identified for preparation of drugs that can be administered to neutralize the free radicals. In the present context the selected medicinal plant is “Origanum majorana” (Family- Lamiaceae) widely known as Marwa in India sub-continent. As the medical professionals show their desires towards composite or lateral treatment, application of drugs with herbal origin gained its importance. \u0000\u0000\u0000\u0000\u0000This review presented various in vitro and in vivo methods used in the antioxidant activity study of O.majorana and observed its efficacy to reduce oxidative stress. \u0000\u0000\u0000\u0000\u0000Referred many reliable sources like Research gate, PubMed, Science Direct, Google scholar, Wiley online library, books to collect all information about the antioxidant activity of the selected plant.\u0000\u0000\u0000\u0000\u0000Used several methods to determine the antioxidants activity of O.majorana, such as superoxide radical scavenging, ferric ion reducing antioxidant potency, thiobarbituric acid reactive substances, hydrogen peroxide scavenging, hydroxyl radical scavenging, lipid peroxidation inhibition, etc. The selected plant contains many phytoconstituents such as gallic acid, ferulic acid, apigenin, catechin, rutin, quercetin, luteolin, linolenic acid, β-sitosterol, and essential oils, which may be responsible for antioxidant activity.\u0000\u0000\u0000\u0000\u0000The review article provides information for investigating and developing new antioxidant methods and major phytoconstituents from O.majorana for better therapy of oxidative stress-mediated complications. \u0000\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46217105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Omega 3 Supplementation Improves Inflammation and Antioxidant Defense in Women with Polycystic Ovary Syndrome 补充欧米茄3改善多囊卵巢综合征妇女的炎症和抗氧化防御
IF 0.9
Current Nutrition & Food Science Pub Date : 2021-11-04 DOI: 10.2174/1573401317666211104121725
Latifa Imen Benharrat, Azzeddine Senouci, Wassila Benhabib, K. Mekki
{"title":"Omega 3 Supplementation Improves Inflammation and Antioxidant Defense in Women with Polycystic Ovary Syndrome","authors":"Latifa Imen Benharrat, Azzeddine Senouci, Wassila Benhabib, K. Mekki","doi":"10.2174/1573401317666211104121725","DOIUrl":"https://doi.org/10.2174/1573401317666211104121725","url":null,"abstract":"\u0000\u0000 Polycystic ovary syndrome (PCOS) is the most common female\u0000endocrine disorder and is accompanied by metabolic syndrome (MS), a risk factor for cardiovascular disorders.\u0000\u0000\u0000\u0000 To evaluate the effect of Omega 3 on the improvement of some metabolic parameters.\u0000\u0000\u0000\u0000\u0000 Sixty women (29±6 years) with PCOS and MS were randomized into two\u0000groups: 30 received supplementation with omega-3 (Doppelherz, Activ, Germany), 3g/day (1g\u0000per capsule and 3 capsules/day), (180mg Eicosapentaenoic Acid (EPA)/ 120mg Docosahexaenoic Acid DHA per day), and 30 were used as controls. Blood samples were drawn at baseline (T0), 3 weeks (T1) and 6 weeks (T2) after start of treatment. We analysed glycemia, lipid\u0000profile, markers of inflammation and oxidative stress.\u0000\u0000\u0000\u0000\u0000In omega-3 group compared to control, a reduction (p<0.05) in glucose levels was\u0000noted at T1 and T2. C-reactive protein (CRP) concentrations were decreased (-25%) at T2. Oxidative stress remain unchanged, but the activity of superoxide dismutase increased as well as\u0000the concentrations of Catalase and thiols at T1 and T2 (p<0.001).\u0000\u0000\u0000\u0000 Omega 3 supplementation improves hyperglycemia, inflammation, and antioxidant defense in PCOS women with MS, and may lead to decreased cardiovascular complications\u0000","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45647792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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