Current Diabetes Reports最新文献

Neonatal and Syndromic Forms of Diabetes.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-03-25 DOI: 10.1007/s11892-024-01567-x

McKinlee R S Gobble, Stephen I Stone

引用次数: 0

The Unique Ethnicity-Specific Aspects of Burden, Pathogenesis and Management of Prediabetes: Insights from Africa.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-03-24 DOI: 10.1007/s11892-025-01581-7

Nancy Kunyiha, Rilwan Adan, Rosslyn Ngugi, Jacqueline Odhiambo, Sairabanu Mohamedrashid Sokwalla

{"title":"The Unique Ethnicity-Specific Aspects of Burden, Pathogenesis and Management of Prediabetes: Insights from Africa.","authors":"Nancy Kunyiha, Rilwan Adan, Rosslyn Ngugi, Jacqueline Odhiambo, Sairabanu Mohamedrashid Sokwalla","doi":"10.1007/s11892-025-01581-7","DOIUrl":"https://doi.org/10.1007/s11892-025-01581-7","url":null,"abstract":"Purposeof review: Prediabetes poses a significant risk of developing diabetes and it's complications. Africa faces specific challenges, hindering early recognition and management of prediabetes. We aimed to understand unique, ethnicity specific aspects of the burden, pathogenesis and management of prediabetes in Africa.Recent findings: The rate of progression from prediabetes to diabetes is higher in African, compared to European populations. Prediabetes in Africans is driven mainly by hyperinsulinemia and reduced hepatic clearance causing obesity and insulin resistance, rather than impaired insulin sensitivity. High risk, difficult to reach individuals in lower socioeconomic strata, benefited from community versus facility-based screening. Intensive lifestyle changes with low calorie or low fat-high fiber diet provide longer lasting effect versus drug monotherapy. Using structured community-based screening, early detection of prediabetes is achievable, requiring dedicated stakeholder engagement. Further research into the etiology and sequencing of pathogenetic anomalies and preventive strategies in African populations is needed.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"25"},"PeriodicalIF":5.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adapting the NIMHD Research Framework for Type 2 Diabetes-Related Disparities.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-03-06 DOI: 10.1007/s11892-025-01580-8

Monica Diaz, Morgan E Braxton, Eyitayo O Owolabi, Timian M Godfrey, Mantej Singh, Aliria M Rascón, Gabriel Q Shaibi

{"title":"Adapting the NIMHD Research Framework for Type 2 Diabetes-Related Disparities.","authors":"Monica Diaz, Morgan E Braxton, Eyitayo O Owolabi, Timian M Godfrey, Mantej Singh, Aliria M Rascón, Gabriel Q Shaibi","doi":"10.1007/s11892-025-01580-8","DOIUrl":"https://doi.org/10.1007/s11892-025-01580-8","url":null,"abstract":"Purpose of review: Type 2 diabetes (T2D) disproportionately impacts minority populations. The National Institute on Minority Health and Health Disparities (NIMHD) developed a research framework to encourage health disparities research that considers a multi-level, multi-domain perspective. The purpose of this review was to describe evidence on the levels and domains that influence T2D disparities among minority populations and use this information to adapt the NIMHD Research Framework for T2D.Recent findings: Screening identified 108 articles published between 2017 and 2023 covering 74,354,597 participants. Articles were classified under the following domains, Biological (18), Behavioral (22), Physical/Built Environment (19), Sociocultural Environment (42), and Health Care System (31). Article levels of influence included Individual (73), Interpersonal (18), Community (36), and Societal (10). Findings were used to adapt the NIMHD Research Framework with an eye towards advancing T2D-related health equity. The results of this review confirm the complex nature of T2D-related disparities and support the notion that drivers operate within and between multiple levels and multiple domains to influence T2D-related outcomes across the lifespan.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"24"},"PeriodicalIF":5.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143565836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Weight Loss on Metabolic Dysfunction Associated Steatohepatitis and Hepatic Fibrosis.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-02-18 DOI: 10.1007/s11892-025-01579-1

Marina W Takawy, Manal F Abdelmalek

{"title":"Impact of Weight Loss on Metabolic Dysfunction Associated Steatohepatitis and Hepatic Fibrosis.","authors":"Marina W Takawy, Manal F Abdelmalek","doi":"10.1007/s11892-025-01579-1","DOIUrl":"https://doi.org/10.1007/s11892-025-01579-1","url":null,"abstract":"Purpose of review: This review highlights the impact of weight loss on metabolic dysfunction associated steatotic liver disease (MASLD), formally known as nonalcoholic fatty liver disease (NAFLD), and its progressive form of metabolic dysfunction associated steatohepatitis (MASH), formally known as nonalcoholic steatohepatitis (NASH). The effects of weight loss, as achieved through lifestyle modification, pharmacotherapy, bariatric surgery or endobariatric procedures on MASLD/MASH and hepatic fibrosis are discussed.Recent findings: Although foundational in the treatment of MASLD/MASH, weight loss through life-style modification is challenging for most patients to achieve and sustain long-term. In patients with MASLD/MASH, a multidisciplinary approach may facilitate success with lifestyle modification, individualized consideration of pharmacotherapies and/or surgical approaches that have potential to lend an improvement in MASLD/MASH. Effective and sustained weight loss improves hepatic steatosis, steatohepatitis and potentially hepatic fibrosis. Improvement in hepatic fibrosis can improve patient-related outcomes associated with complications of advanced hepatic fibrosis or cirrhosis in patients with MASLD/MASH. Identifying risk factors that influence MASLD/MASH and early implementation of therapeutic weight loss strategies may improve chronic liver injury and decrease risk for adverse clinical outcomes related to progressive hepatic fibrosis attributable to MASLD/MASH.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"23"},"PeriodicalIF":5.2,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Type 1 Diabetes Genetic Risk Scores: History, Application and Future Directions.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-02-08 DOI: 10.1007/s11892-025-01575-5

Mustafa Tosur, Suna Onengut-Gumuscu, Maria J Redondo

{"title":"Type 1 Diabetes Genetic Risk Scores: History, Application and Future Directions.","authors":"Mustafa Tosur, Suna Onengut-Gumuscu, Maria J Redondo","doi":"10.1007/s11892-025-01575-5","DOIUrl":"10.1007/s11892-025-01575-5","url":null,"abstract":"Purpose of review: To review the genetics of type 1 diabetes (T1D) and T1D genetic risk scores, focusing on their development, research and clinical applications, and future directions.Recent findings: More than 90 genetic loci have been linked to T1D risk, with approximately half of the genetic risk attributable to the human leukocyte antigen (HLA) locus, along with non-HLA loci that have smaller effects to disease risk. The practical use of T1D genetic risk scores simplifies the complex genetic information, within the HLA and non-HLA regions, by combining the additive effect and interactions of single nucleotide polymorphisms (SNPs) associated with risk. Genetic risk scores have proven to be useful in various aspects, including classifying diabetes (e.g., distinguishing between T1D vs. neonatal, type 2 or other diabetes types), predicting the risk of developing T1D, assessing the prognosis of the clinical course (e.g., determining the risk of developing insulin dependence and glycemic control), and research into the heterogeneity of diabetes (e.g., atypical diabetes). However, there are gaps in our current knowledge including the specific sets of genes that regulate transition between preclinical stages of T1D, response to disease modifying therapies, and other outcomes of interest such as persistence of beta cell function. Several T1D genetic risk scores have been developed and shown to be valuable in various contexts, from classification of diabetes to providing insights into its etiology and predicting T1D risk across different stages of T1D. Further research is needed to develop and validate T1D genetic risk scores that are effective across all populations and ancestries. Finally, barriers such as cost, and training of medical professionals have to be addressed before the use of genetic risk scores can be incorporated into routine clinical practice.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"22"},"PeriodicalIF":5.2,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Systematic Review of Interventions for the Transition to Adult Healthcare for Young People with Diabetes.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-02-01 DOI: 10.1007/s11892-025-01578-2

Sean DeLacey, Jaclyn Papadakis, Steven James, Laura Cudizio, Sze May Ng, Sarah K Lyons, Nisa M Maruthur, Aleksandra Araszkiewicz, Apoorva Gomber, Frank J Snoek, Eva Toft, Carine de Beaufort, Jill Weissberg-Benchell

{"title":"A Systematic Review of Interventions for the Transition to Adult Healthcare for Young People with Diabetes.","authors":"Sean DeLacey, Jaclyn Papadakis, Steven James, Laura Cudizio, Sze May Ng, Sarah K Lyons, Nisa M Maruthur, Aleksandra Araszkiewicz, Apoorva Gomber, Frank J Snoek, Eva Toft, Carine de Beaufort, Jill Weissberg-Benchell","doi":"10.1007/s11892-025-01578-2","DOIUrl":"https://doi.org/10.1007/s11892-025-01578-2","url":null,"abstract":"Purpose of review: The transition to adult healthcare is difficult for young adults with diabetes, with declining glycemic control and reduced healthcare utilization. Efforts are needed to facilitate an effective transfer of care. Our study aimed to systematically review the literature and identify studies evaluating the effectiveness of interventions designed to improve transition readiness and/or the transfer to adult care, describe their characteristics and outcomes, and identify areas for future research.Recent findings: Twenty-six studies were included with one randomized control trial and many pre-post studies observing the impact of transition programs. Generally, interventions had no clear benefit on metabolic outcomes, with variable improvement in care satisfaction and transition readiness. Studies often did not satisfy quality metrics, report important contextual factors (e.g. race, ethnicity) or involve family members. The current literature on interventions to improve transition readiness and transfer of care outcomes in young adults with diabetes is relatively limited with few studies applying rigorous methods. Future studies should apply formal methodology, include both medical and psychosocial outcomes and account for patient and health system context.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"21"},"PeriodicalIF":5.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subtypes of Insulin Restriction in Diabetes Management: A Systematic Review.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-01-27 DOI: 10.1007/s11892-025-01577-3

Aislinn B Beam, Deborah J Wiebe

引用次数: 0

Contextualization of Diabetes: A Review of Reviews from Organisation for Economic Co-operation and Development (OECD) Countries.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-01-24 DOI: 10.1007/s11892-024-01574-y

Sieara Plebon-Huff, Hubi Haji-Mohamed, Helene Gardiner, Samantha Ghanem, Jessica Koh, Allana G LeBlanc

{"title":"Contextualization of Diabetes: A Review of Reviews from Organisation for Economic Co-operation and Development (OECD) Countries.","authors":"Sieara Plebon-Huff, Hubi Haji-Mohamed, Helene Gardiner, Samantha Ghanem, Jessica Koh, Allana G LeBlanc","doi":"10.1007/s11892-024-01574-y","DOIUrl":"10.1007/s11892-024-01574-y","url":null,"abstract":"Purpose of review: The prevalence of diabetes is rising around the world and represents an important public health concern. Unlike individual-level risk and protective factors related to the etiology of diabetes, contextual risk factors have been much less studied. Identification of contextual factors related to the risk of type 1 and type 2 diabetes in Organisation for Economic Co-operation and Development (OECD) countries may help health professionals, researchers, and policymakers to improve surveillance, develop policies and programs, and allocate funding.Recent findings: Among 4,470 potential articles, 48 were included in this review. All reviews were published in English between 2005 and 2023 and were conducted in over 20 different countries. This review identified ten upstream contextual risk factors related to type 1 and type 2 diabetes risk, including income, employment, education, immigration, race/ethnicity, geography, rural/urban status, built environment, environmental pollution, and food security/environment. The ten upstream contextual risk factors identified this review may be integrated into diabetes research, surveillance and prevention activities to help promote better outcomes for people at risk or living with diabetes in OECD countries. Additional research is needed to better quantify the measures of associations between emerging key contextual factors and diabetes outcomes.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"19"},"PeriodicalIF":5.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143028153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Value of Medical Nutrition Therapy and Diabetes Self-Management Education and Support in Diabetes Care and Education: A Call to Action to Increase Referrals and Recognize Insurance Coverage Variation.

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-01-23 DOI: 10.1007/s11892-024-01573-z

Amy Hess-Fischl

{"title":"The Value of Medical Nutrition Therapy and Diabetes Self-Management Education and Support in Diabetes Care and Education: A Call to Action to Increase Referrals and Recognize Insurance Coverage Variation.","authors":"Amy Hess-Fischl","doi":"10.1007/s11892-024-01573-z","DOIUrl":"https://doi.org/10.1007/s11892-024-01573-z","url":null,"abstract":"Purpose of review: Evidence over the past few decades have proven the benefits and cost savings of diabetes self-management education and support (DSMES) and medical nutrition therapy (MNT). Yet, the benefits continue to be underutilized. Little evidence is available to definitively assess insurance coverage for both services. Strategies are presented to more efficiently assess coverage as well as Identify methods to increase referrals and more effectively bill for both services.Recent findings: Estimated statistics for both type 1 and type 2 diabetes reveal increases globally, especially in those under 20 and over 65. Individuals meeting the current A1C guidelines are still well below current recommendations. The economic costs of diabetes continue to rise. Both DSMES and MNT are effective, cost-saving methods that are critical components to the ongoing care of people with diabetes. While insurance coverage does vary based on each specific type, billing correctly and following the requirements for NSDSMES are essential to receive appropriate reimbursement for services.","PeriodicalId":10898,"journal":{"name":"Current Diabetes Reports","volume":"25 1","pages":"18"},"PeriodicalIF":5.2,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Addressing Diabetes Distress in Primary Care: Where Are We Now, and Where Do We Need to Go? 解决初级保健中的糖尿病困扰：我们现在在哪里，我们需要去哪里？

IF 5.2 2区医学

Current Diabetes Reports Pub Date : 2025-01-18 DOI: 10.1007/s11892-025-01576-4

Marisa Kostiuk, E Seth Kramer, Andrea Nederveld, Danielle M Hessler, Lawrence Fisher, Jessica A Parascando, Tamara K Oser

引用次数: 0