Current Ophthalmology Reports最新文献

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A systematic review of acute zonal occult outer retinopathy with a focus on attempted treatment modalities. 对急性区域性隐匿性外视网膜病变的系统回顾,重点是尝试治疗方式。
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-12-01 DOI: 10.1007/s40135-022-00305-4
Benjamin R Lin, Jonathan F Russell, Hasenin Al-Khersan, Raquel Goldhardt
{"title":"A systematic review of acute zonal occult outer retinopathy with a focus on attempted treatment modalities.","authors":"Benjamin R Lin, Jonathan F Russell, Hasenin Al-Khersan, Raquel Goldhardt","doi":"10.1007/s40135-022-00305-4","DOIUrl":"10.1007/s40135-022-00305-4","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9236774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Outcomes of Pythium keratitis: a meta-analysis of individual patient data. 角膜炎的预后:个体患者数据的荟萃分析。
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-12-01 Epub Date: 2022-11-10 DOI: 10.1007/s40135-022-00302-7
Binh Cao, Vishnu Teja Gonugunta, Naveen Radhakrishnan, Prajna Lalitha, Bharat Gurnani, Kirandeep Kaur, Geetha Iyer, Shweta Agarwal, Bhaskar Srinivasan, Jeremy D Keenan, N Venkatesh Prajna
{"title":"Outcomes of Pythium keratitis: a meta-analysis of individual patient data.","authors":"Binh Cao, Vishnu Teja Gonugunta, Naveen Radhakrishnan, Prajna Lalitha, Bharat Gurnani, Kirandeep Kaur, Geetha Iyer, Shweta Agarwal, Bhaskar Srinivasan, Jeremy D Keenan, N Venkatesh Prajna","doi":"10.1007/s40135-022-00302-7","DOIUrl":"10.1007/s40135-022-00302-7","url":null,"abstract":"<p><strong>Background: </strong>Pythium keratitis is a difficult-to-treat corneal infection.</p><p><strong>Methods: </strong>A meta-analysis of individual patient data from observational studies of Pythium keratitis was performed. The outcomes of interest were therapeutic penetrating keratoplasty (TPK) and globe removal (evisceration, enucleation, or exenteration); the main exposures were linezolid and azithromycin use.</p><p><strong>Findings: </strong>Of 46 eligible articles, individual patient data were available for 306 eyes (34 studies). Pythium keratitis was associated with high rates of TPK (80%, 95%CI 70-87%) and globe removal (25%, 95%CI 13-43). In multivariable models adjusting for age and country, fewer TPKs were performed in patients treated with azithromycin (RR=0.80, 95%CI 0.67-0.96; <i>P</i>=0.04) and linezolid (RR=0.82, 95%CI 0.67-0.99; <i>P</i>=0.02).</p><p><strong>Conclusions: </strong>Studies of Pythium keratitis reported high rates of TPK and globe removal. Use of azithromycin and linezolid was associated with a lower rate of TPK. While promising, these results should be interpreted with caution given the biases inherent to observational studies.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ocular Surface Ion Transport and Dry Eye Disease. 眼表面离子迁移与干眼症
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-12-01 Epub Date: 2022-10-20 DOI: 10.1007/s40135-022-00295-3
Ethan S Lindgren, Onur Cil, Alan S Verkman, Neel D Pasricha
{"title":"Ocular Surface Ion Transport and Dry Eye Disease.","authors":"Ethan S Lindgren, Onur Cil, Alan S Verkman, Neel D Pasricha","doi":"10.1007/s40135-022-00295-3","DOIUrl":"10.1007/s40135-022-00295-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review the role of ocular surface epithelial (corneal and conjunctival) ion transporters in the pathogenesis and treatment of dry eye disease (DED).</p><p><strong>Recent findings: </strong>Currently, anti-inflammatory agents are the mainstay of DED treatment, though there are several agents in development that target ion transport proteins on the ocular surface, acting by pro-secretory or anti-absorptive mechanisms to increase the tear fluid Film volume. Activation or inhibition of selected ion transporters can alter tear fluid osmolality, driving water transport onto the ocular surface via osmosis. Several ion transporters have been proposed as potential therapeutic targets for DED, including the cystic fibrosis transmembrane conductance regulator (CFTR), calcium-activated chloride channels (CaCCs), and the epithelial sodium channel (ENaC).</p><p><strong>Summary: </strong>Ocular surface epithelial cell ion transporters are promising targets for pro-secretory and anti-absorptive therapies of DED.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49646151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on the Light-Adjustable Lens (LAL) 可调光镜头(LAL)的最新进展
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-28 DOI: 10.1007/s40135-022-00306-3
Gabriel A Quesada, K. Waltz, Rodrigo A Quesada, León Colindres, Eduardo Alas, Amarilis Portillo, Rafael Perez-Varela, Pablo Ortiz
{"title":"Update on the Light-Adjustable Lens (LAL)","authors":"Gabriel A Quesada, K. Waltz, Rodrigo A Quesada, León Colindres, Eduardo Alas, Amarilis Portillo, Rafael Perez-Varela, Pablo Ortiz","doi":"10.1007/s40135-022-00306-3","DOIUrl":"https://doi.org/10.1007/s40135-022-00306-3","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47476708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Radiation Cataract Management: Outcomes in Individuals with Uveal Melanoma 放射后白内障治疗:葡萄膜黑色素瘤患者的疗效
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-25 DOI: 10.1007/s40135-022-00304-5
Paula A. Sepulveda-Beltran, H. Levine, A. Gibbons, A. Maharaj, Daniel S Choi, Jaime D. Martinez, Z. Corrêa, G. Amescua, J. Harbour
{"title":"Post-Radiation Cataract Management: Outcomes in Individuals with Uveal Melanoma","authors":"Paula A. Sepulveda-Beltran, H. Levine, A. Gibbons, A. Maharaj, Daniel S Choi, Jaime D. Martinez, Z. Corrêa, G. Amescua, J. Harbour","doi":"10.1007/s40135-022-00304-5","DOIUrl":"https://doi.org/10.1007/s40135-022-00304-5","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43031406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demodex Blepharitis: Its Role and Treatment in Ocular Surface Disease 蠕形螨性睑炎:在眼表疾病中的作用及治疗
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-11 DOI: 10.1007/s40135-022-00300-9
Nicole Duncan, Priyanka Sood, Sumitra S. Khandelwal
{"title":"Demodex Blepharitis: Its Role and Treatment in Ocular Surface Disease","authors":"Nicole Duncan, Priyanka Sood, Sumitra S. Khandelwal","doi":"10.1007/s40135-022-00300-9","DOIUrl":"https://doi.org/10.1007/s40135-022-00300-9","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47177528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Potential of Stem Cells as Treatment for Ocular Surface Diseases 干细胞治疗眼表疾病的潜力
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-11 DOI: 10.1007/s40135-022-00303-6
A. Serrano, K. Osei, Marcela Huertas-Bello, Alfonso L. Sabater
{"title":"The Potential of Stem Cells as Treatment for Ocular Surface Diseases","authors":"A. Serrano, K. Osei, Marcela Huertas-Bello, Alfonso L. Sabater","doi":"10.1007/s40135-022-00303-6","DOIUrl":"https://doi.org/10.1007/s40135-022-00303-6","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52779269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral Ulcerative Keratitis: Management 外周溃疡性角膜炎的治疗
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-09 DOI: 10.1007/s40135-022-00301-8
Amol A. Sura
{"title":"Peripheral Ulcerative Keratitis: Management","authors":"Amol A. Sura","doi":"10.1007/s40135-022-00301-8","DOIUrl":"https://doi.org/10.1007/s40135-022-00301-8","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44276201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intense Pulse Light Therapy for Meibomian Gland Dysfunction 强脉冲光治疗睑板腺功能障碍
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-07 DOI: 10.1007/s40135-022-00297-1
Jeremy J. Kudrna, Clever Nguyen, Gargi K. Vora
{"title":"Intense Pulse Light Therapy for Meibomian Gland Dysfunction","authors":"Jeremy J. Kudrna, Clever Nguyen, Gargi K. Vora","doi":"10.1007/s40135-022-00297-1","DOIUrl":"https://doi.org/10.1007/s40135-022-00297-1","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44463435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on the Management of Acanthamoeba Keratitis 棘阿米巴角膜炎管理的最新进展
IF 0.9
Current Ophthalmology Reports Pub Date : 2022-11-05 DOI: 10.1007/s40135-022-00296-2
Colton McCoy, Shaivi Patel, P. Thulasi
{"title":"Update on the Management of Acanthamoeba Keratitis","authors":"Colton McCoy, Shaivi Patel, P. Thulasi","doi":"10.1007/s40135-022-00296-2","DOIUrl":"https://doi.org/10.1007/s40135-022-00296-2","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42541686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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