A. Polyakov, Dmitry V. Davydov, I. Novikova, A. L. Sugaipov, O. Kuznetsova, Elena A. Naumova
{"title":"Modern strategy and standards of treatment of lower eyelid skin malignant neoplasms","authors":"A. Polyakov, Dmitry V. Davydov, I. Novikova, A. L. Sugaipov, O. Kuznetsova, Elena A. Naumova","doi":"10.17816/ov114946","DOIUrl":"https://doi.org/10.17816/ov114946","url":null,"abstract":"Cases of surgical treatment of basal cell skin carcinoma of the lower eyelid are rarely described in the world literature. Perhaps this is due to the search for new non-surgical treatment methods or to the fact that this localization is poorly represented in the total incidence of basal cell skin cancer. However, the operative method, recommended as the main line of treatment by both domestic and foreign clinical recommendations, is still recognized as the most radical and aesthetically acceptable method of treatment. Non-radical treatment of the tumor leads, in turn, to relapses of the disease, to the emergence of systemic metastatic foci due to the lymphogenic and hematogenic spread of tumor cells. In the article we describe the experience of surgical treatment of patients suffering from basal cell skin carcinoma of the lower eyelid of varying degrees of extension.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"26 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82522324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of Pharmacological Treatments for Presbyopia","authors":"F. Vejarano, Jorge Alió, R. Iribarren","doi":"10.1007/s40135-023-00307-w","DOIUrl":"https://doi.org/10.1007/s40135-023-00307-w","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"11 1","pages":"13-19"},"PeriodicalIF":0.9,"publicationDate":"2023-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43983386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surfing the COVID-19 Tsunami with Teleophthalmology: the Advent of New Models of Eye Care.","authors":"Giselle Ricur, Joshua Reyes, Eduardo Alfonso, Raul Guillermo Marino","doi":"10.1007/s40135-023-00308-9","DOIUrl":"https://doi.org/10.1007/s40135-023-00308-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this article, we reviewed the impact resulting from the COVID-19 pandemic on the traditional model of care in ophthalmology.</p><p><strong>Recent findings: </strong>Though virtual eye care has been present for more than 20 years, the COVID-19 pandemic has established a precedent to seriously consider its role in the evolving paradigm of vision and eye care. New hybrid models of care have enhanced or replaced traditional synchronous and asynchronous visits. The increased use of smart phoneography and mobile applications enhanced the remote examination of patients. Use of e-learning became a mainstream tool to continue accessing education and training.</p><p><strong>Summary: </strong>Teleophthalmology has demonstrated its value for screening, examining, diagnosing, monitoring treatment, and increasing access to education. However, much of the progress made following the COVID-19 pandemic is at risk of being lost as society pushes to reestablish normalcy. Further studies during the new norm are required to prove a more permanent role for virtual eye care.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"11 1","pages":"1-12"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10717730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamin R Lin, Jonathan F Russell, Hasenin Al-Khersan, Raquel Goldhardt
{"title":"A systematic review of acute zonal occult outer retinopathy with a focus on attempted treatment modalities.","authors":"Benjamin R Lin, Jonathan F Russell, Hasenin Al-Khersan, Raquel Goldhardt","doi":"10.1007/s40135-022-00305-4","DOIUrl":"10.1007/s40135-022-00305-4","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 4","pages":"168-178"},"PeriodicalIF":0.9,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9236774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Binh Cao, Vishnu Teja Gonugunta, Naveen Radhakrishnan, Prajna Lalitha, Bharat Gurnani, Kirandeep Kaur, Geetha Iyer, Shweta Agarwal, Bhaskar Srinivasan, Jeremy D Keenan, N Venkatesh Prajna
{"title":"Outcomes of Pythium keratitis: a meta-analysis of individual patient data.","authors":"Binh Cao, Vishnu Teja Gonugunta, Naveen Radhakrishnan, Prajna Lalitha, Bharat Gurnani, Kirandeep Kaur, Geetha Iyer, Shweta Agarwal, Bhaskar Srinivasan, Jeremy D Keenan, N Venkatesh Prajna","doi":"10.1007/s40135-022-00302-7","DOIUrl":"10.1007/s40135-022-00302-7","url":null,"abstract":"<p><strong>Background: </strong>Pythium keratitis is a difficult-to-treat corneal infection.</p><p><strong>Methods: </strong>A meta-analysis of individual patient data from observational studies of Pythium keratitis was performed. The outcomes of interest were therapeutic penetrating keratoplasty (TPK) and globe removal (evisceration, enucleation, or exenteration); the main exposures were linezolid and azithromycin use.</p><p><strong>Findings: </strong>Of 46 eligible articles, individual patient data were available for 306 eyes (34 studies). Pythium keratitis was associated with high rates of TPK (80%, 95%CI 70-87%) and globe removal (25%, 95%CI 13-43). In multivariable models adjusting for age and country, fewer TPKs were performed in patients treated with azithromycin (RR=0.80, 95%CI 0.67-0.96; <i>P</i>=0.04) and linezolid (RR=0.82, 95%CI 0.67-0.99; <i>P</i>=0.02).</p><p><strong>Conclusions: </strong>Studies of Pythium keratitis reported high rates of TPK and globe removal. Use of azithromycin and linezolid was associated with a lower rate of TPK. While promising, these results should be interpreted with caution given the biases inherent to observational studies.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 4","pages":"198-208"},"PeriodicalIF":0.9,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10211475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9553049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ethan S Lindgren, Onur Cil, Alan S Verkman, Neel D Pasricha
{"title":"Ocular Surface Ion Transport and Dry Eye Disease.","authors":"Ethan S Lindgren, Onur Cil, Alan S Verkman, Neel D Pasricha","doi":"10.1007/s40135-022-00295-3","DOIUrl":"10.1007/s40135-022-00295-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review the role of ocular surface epithelial (corneal and conjunctival) ion transporters in the pathogenesis and treatment of dry eye disease (DED).</p><p><strong>Recent findings: </strong>Currently, anti-inflammatory agents are the mainstay of DED treatment, though there are several agents in development that target ion transport proteins on the ocular surface, acting by pro-secretory or anti-absorptive mechanisms to increase the tear fluid Film volume. Activation or inhibition of selected ion transporters can alter tear fluid osmolality, driving water transport onto the ocular surface via osmosis. Several ion transporters have been proposed as potential therapeutic targets for DED, including the cystic fibrosis transmembrane conductance regulator (CFTR), calcium-activated chloride channels (CaCCs), and the epithelial sodium channel (ENaC).</p><p><strong>Summary: </strong>Ocular surface epithelial cell ion transporters are promising targets for pro-secretory and anti-absorptive therapies of DED.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 1","pages":"188-197"},"PeriodicalIF":0.9,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10783585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49646151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel A Quesada, K. Waltz, Rodrigo A Quesada, León Colindres, Eduardo Alas, Amarilis Portillo, Rafael Perez-Varela, Pablo Ortiz
{"title":"Update on the Light-Adjustable Lens (LAL)","authors":"Gabriel A Quesada, K. Waltz, Rodrigo A Quesada, León Colindres, Eduardo Alas, Amarilis Portillo, Rafael Perez-Varela, Pablo Ortiz","doi":"10.1007/s40135-022-00306-3","DOIUrl":"https://doi.org/10.1007/s40135-022-00306-3","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 1","pages":"228 - 232"},"PeriodicalIF":0.9,"publicationDate":"2022-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47476708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paula A. Sepulveda-Beltran, H. Levine, A. Gibbons, A. Maharaj, Daniel S Choi, Jaime D. Martinez, Z. Corrêa, G. Amescua, J. Harbour
{"title":"Post-Radiation Cataract Management: Outcomes in Individuals with Uveal Melanoma","authors":"Paula A. Sepulveda-Beltran, H. Levine, A. Gibbons, A. Maharaj, Daniel S Choi, Jaime D. Martinez, Z. Corrêa, G. Amescua, J. Harbour","doi":"10.1007/s40135-022-00304-5","DOIUrl":"https://doi.org/10.1007/s40135-022-00304-5","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 1","pages":"218 - 227"},"PeriodicalIF":0.9,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43031406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicole Duncan, Priyanka Sood, Sumitra S. Khandelwal
{"title":"Demodex Blepharitis: Its Role and Treatment in Ocular Surface Disease","authors":"Nicole Duncan, Priyanka Sood, Sumitra S. Khandelwal","doi":"10.1007/s40135-022-00300-9","DOIUrl":"https://doi.org/10.1007/s40135-022-00300-9","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 1","pages":"107 - 113"},"PeriodicalIF":0.9,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47177528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Serrano, K. Osei, Marcela Huertas-Bello, Alfonso L. Sabater
{"title":"The Potential of Stem Cells as Treatment for Ocular Surface Diseases","authors":"A. Serrano, K. Osei, Marcela Huertas-Bello, Alfonso L. Sabater","doi":"10.1007/s40135-022-00303-6","DOIUrl":"https://doi.org/10.1007/s40135-022-00303-6","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"10 1","pages":"209 - 217"},"PeriodicalIF":0.9,"publicationDate":"2022-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52779269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}