Current Fungal Infection Reports最新文献_第9页

Candida Onychomycosis: an Old Problem in Modern Times 念珠菌性甲真菌病：一个现代的老问题

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-11 DOI: 10.1007/s12281-020-00394-3

Tirado-Sánchez Andrés, Bonifaz Alexandro

引用次数: 6

Emerging Fungal Cutaneous Infections in Immunocompromised Patients 免疫功能低下患者出现的真菌皮肤感染

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-09 DOI: 10.1007/s12281-020-00395-2

Aditya Chandorkar, J. Simkins

引用次数: 1

Candida Infections in Immunocompetent Hosts: Pathogenesis and Diagnosis 免疫正常宿主的念珠菌感染:发病机制和诊断

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-09 DOI: 10.1007/s12281-020-00392-5

S. Rudramurthy, Shreya Singh

引用次数: 4

Cutaneous Fungal Infections in Left Ventricular Assist Device Recipients 左心室辅助装置接受者的皮肤真菌感染

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-06 DOI: 10.1007/s12281-020-00396-1

J. Peraza, Y. Puius

引用次数: 0

Innovative Approaches for Histoplasma Detection 组织浆检测的创新方法

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-06 DOI: 10.1007/s12281-020-00393-4

D. Cáceres, Norma B Fernández, S. Lockhart

引用次数: 2

Combat trauma-related invasive fungal wound infections. 对抗创伤相关的侵袭性真菌伤口感染。

IF 2.3

Current Fungal Infection Reports Pub Date : 2020-06-01 Epub Date: 2020-04-16 DOI: 10.1007/s12281-020-00385-4

David R Tribble, Anuradha Ganesan, Carlos J Rodriguez

{"title":"Combat trauma-related invasive fungal wound infections.","authors":"David R Tribble, Anuradha Ganesan, Carlos J Rodriguez","doi":"10.1007/s12281-020-00385-4","DOIUrl":"10.1007/s12281-020-00385-4","url":null,"abstract":"Purpose of review: This review highlights research from the past five years on combat trauma-related invasive fungal wound infections (IFIs) with a focus on risk stratification to aid patient management, microbiology, and diagnostics.Recent findings: A revised classification scheme stratifies wounds into three risk groups: IFI, High Suspicion of IFI, and Low Suspicion of IFI. This stratification is based on persistence of wound necrosis and laboratory fungal evidence, presence of signs/symptoms of deep soft-tissue infections, and the need for antifungals. Use of this classification could allow for prioritization of antifungal therapy. Further, IFIs delay wound healing, particularly when caused by fungi of the order Mucorales. Lastly, molecular sequencing offers promising and complimentary results to the gold standard histopathology.Summary: Optimal management of combat-related IFIs depends on early tissue-based diagnosis with aggressive surgical debridement and concomitant dual antifungal therapy. Further research on clinical decision support tools and rapid diagnostics are needed.","PeriodicalId":10813,"journal":{"name":"Current Fungal Infection Reports","volume":"14 2","pages":"186-196"},"PeriodicalIF":2.3,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360332/pdf/nihms-1585309.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38160167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mycetomas in the Endemic Area of Argentina 阿根廷特有地区的Mycetomas

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-01 DOI: 10.1007/s12281-020-00382-7

J. Serrano, A. Dorado, Y. Chacón, N. Fortuny, R. Valdez

引用次数: 1

Azole-resistant Aspergillus and Echinocandin-resistant Candida - What are the treatment options? 抗唑曲霉和抗棘白菌假丝酵母-有什么治疗选择?

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-06-01 Epub Date: 2020-03-26 DOI: 10.1007/s12281-020-00379-2

Alison R Novak, Mary E Bradley, Tyree H Kiser, Scott W Mueller

{"title":"Azole-resistant Aspergillus and Echinocandin-resistant Candida - What are the treatment options?","authors":"Alison R Novak, Mary E Bradley, Tyree H Kiser, Scott W Mueller","doi":"10.1007/s12281-020-00379-2","DOIUrl":"https://doi.org/10.1007/s12281-020-00379-2","url":null,"abstract":"Purpose of review: This review summarizes current treatment options for echinocandin-resistant Candida spp. (ERC) and azole-resistant Aspergillus fumigatus (ARAF), emphasizing recent in vitro/in vivo data, clinical reports, and consensus statements.Recent findings: Advances in ERC and ARAF treatment are limited to specific antifungal combinations and dose optimization but remain reliant on amphotericin products. Although novel antifungals may provide breakthroughs in the treatment of resistant fungi, these agents are not yet available. Early identification and appropriate treatment remain a paramount, albeit elusive, task.Summary: When either ERC or ARAF are suspected or proven, amphotericin products remain the cornerstone of initial therapy. For ERC, azoles are de-escalation options for susceptible isolates in stable patients to avoid amphotericin toxicities. Although combination echinocandin with high-dose salvage posaconazole or isavuconazole may be attempted in ARAF, it requires careful consideration following patient stabilization. Future research defining optimal therapies and early identification of ERC and ARAF is of extreme importance.","PeriodicalId":10813,"journal":{"name":"Current Fungal Infection Reports","volume":"14 2","pages":"141-152"},"PeriodicalIF":1.4,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12281-020-00379-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38189731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Antifungal Penetration and Distribution into Organs and Tissue 抗真菌药物在器官和组织中的渗透和分布

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-05-21 DOI: 10.1007/s12281-020-00390-7

Kayla R. Stover, J. Cleary

引用次数: 4

Implications of Evolving and Emerging Pharmacokinetic-Pharmacodynamic Research for Triazoles and Echinocandins 三唑类和棘球蚴类药物动力学研究进展和新出现的意义

IF 1.4

Current Fungal Infection Reports Pub Date : 2020-05-19 DOI: 10.1007/s12281-020-00391-6

J. Cota, S. Giancola, Taylor M. Benavides, N. Wiederhold

引用次数: 0