Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.099
Lucie Petroušová, Jakub Sulženko
{"title":"(Popliteal artery entrapment syndrome)","authors":"Lucie Petroušová, Jakub Sulženko","doi":"10.33678/cor.2022.099","DOIUrl":"https://doi.org/10.33678/cor.2022.099","url":null,"abstract":"","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42535770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.126
G. Fadieienko, O. E. Gridnyev, O. Kurinna, N. Chereliuk
{"title":"Gut microbiota changes in nonalcoholic fatty liver disease and concomitant coronary artery disease","authors":"G. Fadieienko, O. E. Gridnyev, O. Kurinna, N. Chereliuk","doi":"10.33678/cor.2022.126","DOIUrl":"https://doi.org/10.33678/cor.2022.126","url":null,"abstract":"Background and the research aim: Nonalcoholic fatty liver disease (NAFLD) bears serious economic conse-quences for the health care system worldwide and Ukraine, in particular. Cardiovascular diseases (CVD) are the main cause of mortality in NAFLD patients. Changes in the gut microbiota composition can be regarded as a potential mechanism of CVD in NAFLD patients. The research aim was the investigation changes in major gut microbiota phylotypes, Bacteroidetes , Firmicutes , and Actinobacteria with quantifi cation of Firmi- cutes/Bacteroidetes in NAFLD patients with concomitant CVD. Materials and methods: There were 109 NAFLD subjects (25 with concomitant arterial hypertension [AH] and 24 with coronary artery disease [CAD]) enrolled. The gut microbiota composition was assessed by qPCR. Results and conclusions: There was a marked tendency towards an increase in the concentration of Bacteroidetes (by 37.11% and 21.30%, respectively) with a decrease in Firmicutes (by 7.38% and 7.77%, respectively) found in both groups with comorbid CAD and AH with the identifi ed changes not reaching a statistical signifi cance. A statistically signifi cant decrease in the concentration of Actinobacteria was revealed in patients with NAFLD with concomitant CAD at 41.37% ( p <0.05) as compared with those with an isolated NAFLD. In patients with concomitant AH, the content of Actinobacteria dropped by 12.35%, which was statistically insignifi cant. There were changes found in the intestinal microbiota composition, namely decrease in Actinobacteria in patients with CAD, which requires further research.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48524228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.114
Asma Amrani-Midoun, N. Laredj, Taki Djebaili, Abdelkader Djelloul, L. Zouli, H. Aoumeur, F. Boukerche, M. Nachi
{"title":"Gender differences in epidemiology and risk factors of acute coronary syndrome in Algerian patients of the Oran city: descriptive cross-sectional study","authors":"Asma Amrani-Midoun, N. Laredj, Taki Djebaili, Abdelkader Djelloul, L. Zouli, H. Aoumeur, F. Boukerche, M. Nachi","doi":"10.33678/cor.2022.114","DOIUrl":"https://doi.org/10.33678/cor.2022.114","url":null,"abstract":"Background and aims: The aim of this study is to determine the role of clinical, lifestyle, and behavioral characteristics on the severity of the disease according to the gender. Methods: We conducted a cross-sectional descriptive study. Results: An initial sample of 1219 patients was admitted for ACS in the cardiology service of Oran-Univer-sity-Hospital-Center. The electrocardiographic results revealed that 34% of the patients had ST-segment elevation myocardial infarction (STEMI) while 66% had non-ST-segment elevation myocardial infarction (NSTEMI). In STEMI patients, the mean age was 60.87±12.20 years. STEMI patients sample included 413 pa- tients with 324 men with a mean age of 59.92±11.78 years and 89 women with a mean age of 64.36±13.13 years. A male predominance observed with a sex-ratio of 3.6. Among STEMI patients, 34.8% of patients had hypertension where it was signifi cantly higher in women than in men (65.6% vs 26.5% respectively, p < 0.05). Diabetes was observed in 31.7% of the whole sample where it was also more common in women compared to men (50.6% vs 26.5%, respectively, p <0.05). Out of the 413 STEMI patients 63.9% had dyslipidemia which was signifi cantly higher in men compared to women (76.5% vs 13.5% respectively, p <0.05), 64.5% of men were current smokers. Out of the 324 STEMI men patients, 46.5% had three risk factors while in the 89 STEMI women patients, 34.8% had four risk factors. Conclusion: Our results demonstrated a higher prevalence of ACS among the studied sample. STEMI patients presented with several cardiovascular risk factors. Sex differences in the ACS presentation and risk factors was also noticed.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47878978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.129
P. Snopek, J. Hasilla, L. Pátrovič, D. Juskanič, J. Benko, M. Samoš
{"title":"Infective endocarditis complicated by brain embolism: a case report","authors":"P. Snopek, J. Hasilla, L. Pátrovič, D. Juskanič, J. Benko, M. Samoš","doi":"10.33678/cor.2022.129","DOIUrl":"https://doi.org/10.33678/cor.2022.129","url":null,"abstract":"Symptomatic neurological complications occur in 15–30% of patients with infective endocarditis. At the same time, other clinically silent cerebral embolisms occur in 35–60% of patients. Staphylococcus aureus is the pathogen that causes nervous system involvement most frequently. We report a case of a 67-year- -old man with infective endocarditis following a dental procedure that manifested as spondylodiscitis and multiple brain embolization, including a brain abscess that required drainage. After six weeks of treatment with broad-spectrum antibiotics and complex supportive therapy, we discharged the patient in a satisfactory mental and somatic condition. The preparation of the patient for cardiac surgery is ongoing.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48976359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.078
Zuzana Komorová, M. Novák, J. Seménka, V. Feitová, P. Nemec, L. Špinarová
{"title":"(Left-right short circuit in an adult woman between the left coronary artery and the sinus coronarius caused by a giant fistula)","authors":"Zuzana Komorová, M. Novák, J. Seménka, V. Feitová, P. Nemec, L. Špinarová","doi":"10.33678/cor.2022.078","DOIUrl":"https://doi.org/10.33678/cor.2022.078","url":null,"abstract":"","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42108055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.111
Mert Sarilar, V. Oktay, Gursu Demirci, D. Oksen, V. Sansoy
{"title":"Periprocedural myocardial injury after elective percutaneous coronary intervention in stable angina pectoris: a tertiary center experience","authors":"Mert Sarilar, V. Oktay, Gursu Demirci, D. Oksen, V. Sansoy","doi":"10.33678/cor.2022.111","DOIUrl":"https://doi.org/10.33678/cor.2022.111","url":null,"abstract":"Background: Periprocedural myocardial injury and its clinical signifi cance in stable patients are still under discussion. This subject has been assessed in many studies with different defi nitions, thresholds, and biomarkers for years. This study aimed to determine the clinical outcomes of periprocedural myocardial injury based on latest 4th UDMI guideline defi nitions. Methods: 238 patients who underwent elective percutaneous coronary intervention at single center were retrospectively enrolled. Patients who developed periprocedural myocardial injury were compared with patients with normal troponin values after the procedure for clinical outcomes. Primary clinical endpoints were death, MI, stroke, refractory angina, target vessel revascularization and hospitalization due to acute coronary syndrome at one year. Results: Periprocedural myocardial injury was observed in 67.2% (n = 160) of patients. Number of lesions and stents, total stent length, total stent diameter, post-dilatation, overlapping stents, bifurcation stenting and SYNTAX score were signifi cantly higher in myocardial injury group. Clinical outcomes occurred in 16 patients, 11 of 16 had myocardial injury group, 5 of 16 had control group. No mortality was seen during the follow-up. Postprocedural troponin elevation was not associated with clinical outcomes (11 vs. 5, p = 0,56). Kaplan–Meier curve of clinical end points did not show any separation between the curves (Log rank test, 95% CI, p = 0,71). Conclusion: Stent size and length, post-dilatation, overlapping stents and stenting of bifurcation lesions lead to increase in myocardial injury. Periprocedural myocardial injury in stable angina does not predict clinical outcomes at one year.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41851547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.100
Ali Dogan, D. Mansuroğlu, Oğuz Konukoğlu, Emrah Ozdemir, Mert Sarilar, Ayda Guler, N. Kurtoglu
{"title":"Impact of invasively determined cardiac power index on survival in patients with advanced chronic heart failure","authors":"Ali Dogan, D. Mansuroğlu, Oğuz Konukoğlu, Emrah Ozdemir, Mert Sarilar, Ayda Guler, N. Kurtoglu","doi":"10.33678/cor.2022.100","DOIUrl":"https://doi.org/10.33678/cor.2022.100","url":null,"abstract":"Background : Hemodynamic parameters have recently emerged as tools for risk stratifi cation of heart failure patients. Cardiac power output (CPO) is an indicator of cardiac performance. Cardiac power index (CPI) is calculated by indexing CPO to body surface area. The study aimed to demonstrate the prognostic role of resting CPI in advanced chronic heart failure patients. Methods : The study included patients with advanced chronic heart failure, ejection fraction below 30%, and classes III and IV functional capacity who had had right and left heart catheterization. A total of 99 patients were enrolled, with those having left ventricular assist device (LVAD) implantation or heart transplantation (HTx) excluded to determine LVAD- and HTx-free survival. Results : Of the 99 patients, 43 patients underwent LVAD and HTx surgery. Of the remaining 56 patients, 19 died (33.9%) over a period of 16 months (median). The value of CPI was associated with cardiac mortality (0.32 vs 0.42, p = 0.003). The cut-off level of CPI for mortality was 0.41 (89.5% sensitivity and 56.8% specifi city). A diminished CPI (<0.41 W/m 2 ) was also associated with high right atrial pressure ( p = 0.016) and pulmonary vascular resistance ( p = 0.012). A Kaplan–Meier survival analysis indicated that long-term survival was signifi cantly reduced in patients with CPI <0.41. Conclusion : Cardiac power index at rest is associated with cardiac mortality in patients with advanced chronic heart failure.","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45096341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.116
M. Hodboďová, A. Krebsová, P. Peldová, R. Polášek, T. Roubíček
{"title":"(PRKAG2 syndrome as a highly arrhythmogenic eventuality in the differential diagnosis of hypertrophic cardiomyopathy - an example of two families with a confirmed causative DNA variant)","authors":"M. Hodboďová, A. Krebsová, P. Peldová, R. Polášek, T. Roubíček","doi":"10.33678/cor.2022.116","DOIUrl":"https://doi.org/10.33678/cor.2022.116","url":null,"abstract":"Hypertrophic cardiomyopathy (HCM) affects 0.2% of the population and is the most common form of here- ditary heart muscle disease in adults. The most frequent cause of HCM are changes in the genes encoding sarcomere proteins. However, up to 10% of patients are affected by another type of systemic genetic dis- ease that has myocardial hypertrophy as only one of its multi-organ manifestations. Among these diseases is PRKAG2 glycogenosis, a rare metabolic storage disorder caused by an inherited defect in the 2 regula-tory subunit of adenosine monophosphate-activated protein kinase (AMPK). In addition to skeletal muscle myopathy, it causes HCMP with a high risk of malignant ventricular and supraventricular arrhythmias and several conduction disorders. Thanks to close collaboration of several departments, we diagnosed two families with a causative DNA variant in the PRKAG2 gene. On the basis of the presented case studies, we document highly variable manifestations of PRKAG2 syndrome and thus highlight the pitfalls in its clinical diagnosis and therapy","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47203870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.112
Mirela Rajčinova, D. Zemánek, Lukas Matera, V. Fabián
{"title":"(Current methods for measurement of arterial stiffness)","authors":"Mirela Rajčinova, D. Zemánek, Lukas Matera, V. Fabián","doi":"10.33678/cor.2022.112","DOIUrl":"https://doi.org/10.33678/cor.2022.112","url":null,"abstract":"","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42226812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cor et vasaPub Date : 2023-06-20DOI: 10.33678/cor.2022.104
Jan Boček, M. Segeťová, J. Beneš, Hanka Wünschová, K. Sedláček, Věra Lánská, J. Kautzner
{"title":"(Implantation of leadless pacemaker (LP) Micra - single center experience)","authors":"Jan Boček, M. Segeťová, J. Beneš, Hanka Wünschová, K. Sedláček, Věra Lánská, J. Kautzner","doi":"10.33678/cor.2022.104","DOIUrl":"https://doi.org/10.33678/cor.2022.104","url":null,"abstract":"","PeriodicalId":10787,"journal":{"name":"Cor et vasa","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43040920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}