The Internet Journal of Alternative Medicine最新文献

{"title":"Anti-Ulcer Effect Of Aspilia Africana (Asteraceae) Leaf Extract On Induced Duodenal Ulcer Of Adult Wistar Rats (Rattus Norvegicus) – A Histological Study","authors":"A. Eweka, A. Eweka","doi":"10.5580/dc1","DOIUrl":"https://doi.org/10.5580/dc1","url":null,"abstract":"Histological studies of the effects of oral administration of extract of Aspilia africana, used in ethno medical practice in Africa for the management of various ailments, on the duodenum of adult Wistar rats previously exposed to varied concentration of hydrochloric acid were carefully studied. The rats (n=30), average weight of 189g were randomly assigned into three treatments (n=24), ‘A’, ‘B’, ‘C’, each (n=8) and control (n=6), D groups. The experimental rats each received 0.5mls of 50% dilute Hydrochloric acid 48hrs prior to administration of the extract. The rats in the treatment groups ‘A’ and ‘B’ received 0.5g/kg and 1g/kg respectively of aqueous extract of Aspilia africana orally through orogastric tube for fourteen days, while the control rats (group D) received equal volume of distilled water without the extract of Aspilia added. The rats in group ‘C’ received only the hydrochloric acid and were sacrificed 72hrs after administration. The rats were fed with growers’ mash purchased from Edo feeds and Flour Mill Ltd, Ewu, Edo state and were given water liberally. The rats were sacrificed on day fifteen of the experiment. The small intestine was carefully dissected out and quickly fixed in 10% formal saline for routine histological study after H&E method. The histological findings indicated that the treated sections of the small intestine showed varying degrees of cellular proliferation and epithelia regeneration. These findings indicate that Aspilia africana consumption may probably have anti-ulcer effects on the duodenal ulcer by its healing effects on the Brunnals gland and epithelia cells of the small intestine of adult Wistar rats. It is recommended that further studies aimed at corroborating these observations be carried out.","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133678849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shavasana Autopsychorelaxation : A self-report measure of cost-effective integrative medicine","authors":"Satendra Singh, Savita Singh, S. Gautam","doi":"10.5580/1149","DOIUrl":"https://doi.org/10.5580/1149","url":null,"abstract":"Yoga produces many beneficial emotional, psychological, behavioral and biological effects. The psychophysiological responses to yoga are opposite to the stress response. Shavasan, yoganidra, meditation and slow, rhythmic pranayam breathing are very effective in calming the mind and promoting psychosomatic health. The physiological benefits which follow shavasana helped cardiac patients with ventricular ectopics 2 become more resilient to stressful conditions and rehabilitation following myocardial infarction. 3","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123806078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Laetrile Work? Another Look at the Mayo Clinic Study (Moertel et al., 1982).","authors":"S. Krashen","doi":"10.5580/7b4","DOIUrl":"https://doi.org/10.5580/7b4","url":null,"abstract":"Moertel et. al. (1992) studied the impact of laetrile on 172 cancer patients and concluded that it had no effect. The study used a mixture of natural and synthetic laetrile that laetrile experts consider to be minimally or not effective, followed an inflexible schedule of administration of laetrile injections, and involved patients \"for which no standard treatment was known to be curative or to extend life expectancy.\" The study is informative, but the results do not support Moertel et. al.'s conclusion that further investigation or use of laetrile is not justified. Despite the widespread belief that Laetrile is ineffective against cancer, there have been only two large-scale clinical studies. I commented on the first study, 1,2 arguing that descriptions of this study in the professional literature give an overly pessimistic view of the efficacy of Laetrile. In the second clinical study, done at the Mayo clinic, Moertel et. al. studied 172 cancer patients “in good general condition” treated with Laetrile and an accompanying diet, and concluded that Laetrile had no effect. They concluded with the recommendation that “further investigation or clinical use of such therapy is not justified (p. 205). 3 The Mayo study has been widely cited and is considered by many to be definitive. When it appeared, Time Magazine ran an article with the title “Laetrlle flunks” with the subtitle “Test shows cancer quackery.” 4 The typical response of the profession is an article in the CA-A Cancer Journal for Physicians, “Unproven methods of cancer management,” which proclaimed that the Mayo study “showed unequivocally that Laetrile is ineffective for cancer therapy” (p. 190). 5 Laetrile supporters, however, have been vocal critics of the Mayo study. Soon after the study appeared, several letters to the editor commenting on Moertel et. al. appeared in the New England Journal of Medicine, and Charles Moertel, the first author of the Mayo study, responded, dealing with some of the criticisms but ignoring others, as we will see below. My commentary will deal with the following points, expanding on remarks made by critics of the Mayo study. The kind of Laetrile used. 1. The way the Laetrile was administered. 2. The use of terminal patients. 3. The interpretation of the results. 4. WHAT KIND OF LAETRILE? In his letter to the editor of the New England Journal of Medicine, Culbert notes that the Mayo study did not use pure amygdalin but a “degraded or decomposed form of it (the putative 'RS-epimer racemic mixture').” 6 The RS epimer racemic mixture is a mixture of natural amygdalin (R-amygdalin) and an isomer, an artificial form (referred to as the S-isomer, or isoamygdalin). Krebs strongly argues against the use of this kind of amygdalin, and maintains that this mixture is less than half as effective as the pure form (see the Appendix below for suggestive evidence that the Mayo mixture might have been even weaker). Krebs, in fact, points out that the mixture “caused unpredic","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115208588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti inflammatory effect of methanolic extract of Hedyotis Umbellata Linn","authors":"S. Mahibalan, S. Jasemine, M. Jesupillai","doi":"10.5580/d52","DOIUrl":"https://doi.org/10.5580/d52","url":null,"abstract":"Objective: To explore anti-inflammatory activity of Hedyotis umbellata Linn.Method : Anti inflammatory activity of methanol extract of aerial parts of Hedyotis Umbellata (MEHU) Linn was studied using Carrageenan induced paw edema model. MEHU reduced paw edema significantly (P<0.05) at 250 mg/kg and 500 mg/kg. Diclofenac sodium was included as standard. Report: MEHU at 250 mg/kg and 500 mg/kg produced significant (P<0.05) reduction on paw edema induced by carrageenan. The activity also comparable to the standard anti-inflammatory agent Diclofenac sodium.Conclusion: From the findings we conclude that Hedyotis umbellata possess antiinflammatory activity.","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115702372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Phenolic acids in some samples of Indian and Nepal Tea by High Performance Liquid Chromatography","authors":"R. Srivastava, Amitabh Singh, S. Misra, U. P. Singh, A. Tiwari","doi":"10.5580/1e54","DOIUrl":"https://doi.org/10.5580/1e54","url":null,"abstract":"The beneficial effects of tea (Camellia sinensis) leaves have already been studied in detail. However, the scientists are keen to explore the exact scientific reasons for such effects. The biochemical analysis of tea samples has indicated that they contain mostly polyphenols, mainly catechins. Catechins are present in food and beverages of plant origin. Keeping this in view, High Performance Liquid Chromatographic analysis was performed to estimate phenolic acids in 26 samples of tea (samples of Indian market brand, Indian tea garden and Nepal tea garden such as Janhit green teaTM (JGT), Tata tea premiumTM (TT ), Brooke bond TaazaTM (BBTZ), Lipton Darjeeling TeaTM (LDT), Tea cityTM (TCT), Taj Mahal TeaTM (TAJM), Tetley TeaTM (TET), Assam dana (DASM), Assam dana 1 (ASMD-1), Assam dana 2 (ASMD-2), Assam Tea (ASM), North Bengal tea (NB), North Bengal dana-1 (DNB-1), North Bengal-2 (DNB-2), North Bengal Upper (NBUP), Darjeeling tea-FOP (DARJ-FOP), Darjeeling tea-FOP1 (DARJ-FOP1), Darjeeling teabrake (DARJ-br), Indian tea garden (Darjeeling-ITGA (DARJ-ITGA), DarjeelingITGB (DARJ-ITGB), Darjeeling-ITGC (DARJ-ITGC) and Nepal tea garden (KP-33A, KP-16A, KP-9A, KPC6 and KP-C2).","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122760315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Beneficial Dietary Hypotensive and Hypolipidaemic Effects of Hyphaene Thebaica ( Doum )","authors":"A. El-Gendy, Asaad El-Mileegy, Essam Desoky Ghyaty, H. A. Malek, Amany A. Mousa","doi":"10.5580/a06","DOIUrl":"https://doi.org/10.5580/a06","url":null,"abstract":"Background: The use of Doum palm fruit which is rich in flavonoids (polyphenols) , saponins and tannins in folk medicine is not surprising. Objectives: This study was done to clarify the role of Doum (Hyphaene thebaica), as a medicinal plant containing flavonoids, saponins and tannins, on blood pressure, blood lipids and lipoproteins in hypertensive patients. Methods: Thirty female patients who were hypertensive, obese and hyperlipidemic were used in the study that extends to 3 months. They were divided into 2 groups each group consisted of 15 patients (control group received antihypertensive drug with similar dose, and Doum group received the same antihypertensive drug with the same dose. and agreed to consume an oral supplement of Doum in a daily dose of 25 mg/kg body weight). Blood pressure, plasma lipids and lipoproteins were followed up in all patients for 3 months. Blood samples were obtained after a 12 to 14 h fast. Concentrations of total cholesterol, triglycerides, HDL, apoA-I and apoB were measured. LDL was calculated according to the Friedewald equation.The recorded values were expressed as means and standard deviations (Mean ±SD). The statistical analyses were performed using the SPSS statistical Package version 12. Results: Compared with the control patients, supplementation with Doum caused a significant decrease in systolic blood pressure, diastolic B.P., total cholesterol, triglycerides, LDL, apoB-concentrations and LDL/HDL ratio, while significantly increasing the concentrations of HDL and apoA-I. Conclusion:These results confirm the benefits of Doum including lowering blood pressure in hypertensive patients and changing blood lipids and lipoproteins in a manner that decreases the risk on the cardiovascular system. More studies are needed support these benefits of Doum.","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129702345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect Of Aqueous Extracts Of Leaves Of Globimetula Cupulata (Dc) Van Tieghem In Normoglycemic Rats","authors":"D. Edem","doi":"10.5580/be4","DOIUrl":"https://doi.org/10.5580/be4","url":null,"abstract":"Globimetula cupulata leaves were evaluated for their hypoglycemic activity in rats. The animals were divided into 4 groups (n=6). Water extract of G. cupulata leaves was administered in graded doses of 0, 300, 600 and 900 mg kg body weight (wt) of experimental animals for 14days. Blood samples were collected by cardiac puncture. The levels of blood glucose were significantly reduced (p < 0.05) by 35.79 – 43.48% on consumption of the extracts, with greater effect exhibited by the 900mg/kg body wt extract. Histological studies showed increases in the number and density of the pancreatic islet cells. The result suggested restorative (protective) effect of the extract on pancreatic islet cells. Administration of aqueous extract of Globimetula cupulata leaves may contribute significantly to the reduction of blood glucose levels by a pancreatotrophic action and possible potentiation of insulin secretion, which may be useful in the treatment of diabetes.","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128733707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring the Oxygenation of Blood During Exercise After Ingesting Wheatgrass Juice","authors":"Michele Handzel, J. Sibert, T. Harvey, H. Deshmukh, C. C. Chambers","doi":"10.5580/257b","DOIUrl":"https://doi.org/10.5580/257b","url":null,"abstract":"Although wheatgrass juice is believed to act as an ergogenic aid, little research has been done to prove its credibility. The purpose of this study was to explore one possible mechanism by which wheatgrass juice improves the human body—blood oxygenation. The ability of wheatgrass juice to increase blood oxygen saturation in the human body during exercise was observed via pulse oximetry. Participants ran on a treadmill for 20 minutes at 75-85% intensity, calculated by each participant's heart rate reserve, on two separate occasions. One session acted as a control and the other involved the ingestion of 2 ounces of wheatgrass juice 20 minutes prior to exercise. As a result of wheatgrass juice ingestion prior to exercise, participants’ blood oxygen saturation was an average of 0.31% higher during exercise than if no wheatgrass juice had been ingested. During an 8 min post-exercise recovery, participants’ blood oxygen saturation was an average of 0.23% higher after wheatgrass juice ingestion than that of a non-wheatgrass recovery. It can be concluded that a mechanism exists in the body that increases blood oxygenation level (SpO2) due to wheatgrass juice consumption.","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116811447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Approach Of Applied Physiology & Yoga To Combat Lifestyle Diseases","authors":"G. Sharma, Luv Sharma, S. Sood","doi":"10.5580/1990","DOIUrl":"https://doi.org/10.5580/1990","url":null,"abstract":"The modern age is ‘the age of stress’ and stress related diseases, which pose a serious challenge to not only medical professionals but to the whole concerned diasporas. In spite of the leaps and bounds in medical sciences, we are surrounded by a very silent but dangerous foe, lifestyle diseases. In our own nation, the sad truth is now out India is headed to become the Diabetic capital of the world. The younger generation i.e. the under 40 age group are up to 10 times more prone to cardiovascular diseases as compared to the corresponding age group in the west. According to an alarming estimate, around the year 2025 A.D., about 91 young people would die per hour from heart related diseases! Diseases directly linked to modern lifestyle like Diabetes, coronary artery diseases, hypertension, obesity, eating disorders, mood disorders, mental illness, psychosomatic disorders, etc are a great threat to human life and constitute the major bulk of morbidity and mortality of the 21st century. Our diet has changed from high fiber, low fat to high fat, low fiber type processed food. Other potent negative factors are decreased physical activity, addiction to smoking, alcohol, drugs, etc. which further lead to obesity, insulin resistance and atherogenic dyslipidemia. This vicious cycle is further compounded by stress and consequent stress related diseases. Stress affects the body through Psycho-neuro-endo-immuno-cyto-axis. Initially during stress, the sympathetic nervous system is activated and via nervous and hormonal responses, the same copes with emergency. However, chronic stress has a very deleterious effect on the body and may enhance development of the lifestyle related diseases named above. Stress and its devastating sequel can be dealt with by reducing and later curing the lifestyle disorders by drastic dietary changes, mind-body therapies including meditation, stress relaxation techniques and yoga. The need of the moment is that Physiologists take a step forward and apply their knowledge of physiology of stress to show stressed masses the path to mental and physical salvation. Applied Physiology has already blended the ancient traditional Indian medicine modalities with modern medical science integrating Body, Breath and Mind well with natural herbs and the science of Ayurveda. The present study was conducted on 60 young and asymptomatic M.B.B.S. students to assess the effect of Shavasana on the recovery process from Cold Pressor Test (CPT) induced stress by recording blood pressure, pulse rate, respiratory rate and rate pressure product i.e. all important cardiorespiratory parameters. All these parameters were recorded in three settings both before and after CPT. Ten minutes of Shavasana showed lowering of all basal parameters in comparison to supine posture which further lowered (p<.05) after long term (4 weeks) Shavasana training. Stress induced by CPT caused rise in all parameters in all three settings; this rise, however, was blunted after 10 mi","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131740872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum lipid profile abnormality in predicting the risk of myocardial infarction in elderly normolipidaemic patients in South Asia: A case-controlled study","authors":"Arun Kumar, R. Sivakanesan","doi":"10.5580/17a0","DOIUrl":"https://doi.org/10.5580/17a0","url":null,"abstract":"BACKGROUND: The major cause of atherosclerosis, dyslipidaemic, acts synergistically with non-lipid risk factors resulting increase in atherogenesis. Increased (TG) and decreased high-density lipoprotein (HDL-C) and the increased TG/HDL-C ratio are considered as major risk factors in the development of Insulin resistance and metabolic syndrome. The accuracy of TG/HDL-C ratio in predicting coronary heart disease (CHD) risk is not properly established by recent research. AIM: The study was undertaken to evaluate the usefulness of lipid ratios TC/HDL-C, TG/HDL-C and LDL/HDL-C in predicting CHD risk in normolipidaemic patients with myocardial infarction and to compare the results with healthy subjects. SETTING & DESIGN: Lipid Profile was determined in 165 normolipidaemic Acute Myocardial Infarction patients and compared them with 165 age/sex-matched controls. MATERIAL & METHODS: Total Cholesterol, Triglycerides, and HDL-cholesterol were analyzed enzymatically using kits obtained from Randox Laboratories Limited, Crumlin, UK. Plasma LDL-cholesterol was determined from the values of total cholesterol and HDLcholesterol using the friedwald's formula. STATISTICS: The values were expressed as means ± standard deviation (SD) and data from patients and controls was compared using students 't'-test. RESULTS AND CONCLUSION: Total cholesterol, TC/HDL-C ratio, Triglycerides, LDL-cholesterol, LDL-C/HDL-C ratio were higher in MI patients (p<0.001). HDL-C concentration was significantly lower in MI patients than controls (p<0.001). Higher ratio of TC/HDL-C, TG/HDL-C and LDL-C/HDL-C was observed in AMI patients compared to controls.","PeriodicalId":107168,"journal":{"name":"The Internet Journal of Alternative Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131168763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}