Contemporary topics in immunobiology最新文献

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Idiotypes, T-cell receptors, and T-B cooperation. 独特型,t细胞受体和T-B合作。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_7
C A Janeway
{"title":"Idiotypes, T-cell receptors, and T-B cooperation.","authors":"C A Janeway","doi":"10.1007/978-1-4615-9131-3_7","DOIUrl":"https://doi.org/10.1007/978-1-4615-9131-3_7","url":null,"abstract":"<p><p>T cells are responsible for virtually all the characteristics of the mammalian immune system except the production of serum antibody, in which they play a vital regulatory role. As such, they are central to our understanding of the immune system. T cells recognize cell-bound antigens with great precision, in association with self MHC antigens. They do this by means of antigen-specific receptors, whose antigen-combining sites are encoded in conventional VH genes. There is evidence that T cells carry at least two kinds of specific receptors, one for MHC antigens and one for non-MHC antigens. Both of these would bear VH-encoded and distinct idiotypic determinants. The process by which antigens associate with MHC-gene products on cell surfaces is poorly understood at present, and so is the process by which the two types of receptors communicate with each other. T cells are divisible into a number of subpopulations playing unique functional roles in the regulation of antibody responses. If one examines them further for other functions, even greater complexity emerges. Thus, all T cells may not have the same kind of receptor, which would not be surprising given the wide variety of functions they perform. Future work will undoubtedly focus on these important questions.</p>","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"9 ","pages":"171-203"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17219215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
An immunologic network. 免疫网络。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_8
D A Rowley, H Köhler, J D Cowan
{"title":"An immunologic network.","authors":"D A Rowley,&nbsp;H Köhler,&nbsp;J D Cowan","doi":"10.1007/978-1-4615-9131-3_8","DOIUrl":"https://doi.org/10.1007/978-1-4615-9131-3_8","url":null,"abstract":"<p><p>The immune system is a complex network of molecules and cells specifically connected by the complementarity of receptors for antigen and receptors for receptors. The network includes multiple positive- and negative-feedback loops, which modulate the type, magnitude, and duration of responses. The great challenge is to devise ways to manipulate the system specifically to induce effective autoimmunity to cancer, to prevent allograft rejection, and to turn off undesirable responses in allergies and autoimmune diseases. Recognition of the immune system as a network helps to explain why these objectives are so difficult and why manipulation of multiple components to achieve desired regulation may be required. But presumably manipulation must be focused on connectivity between receptor for epitope and receptor for receptor to achieve a high degree of specific regulation.</p>","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"9 ","pages":"205-30"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17503338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Evidence for membrane-bound antibodies directed against antigens expressed on tumors. 针对肿瘤抗原表达的膜结合抗体的证据。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_8
S von Kleist, M King, C Huet
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引用次数: 6
A review of data, problems, and open questions pertaining to in situ tumor immunity. 回顾有关原位肿瘤免疫的数据、问题和开放性问题。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_1
S W Russell, I P Witz, R B Herberman
{"title":"A review of data, problems, and open questions pertaining to in situ tumor immunity.","authors":"S W Russell,&nbsp;I P Witz,&nbsp;R B Herberman","doi":"10.1007/978-1-4684-3677-8_1","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_1","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"1-20"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18045833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Cancer: a problem in somatic cell evolution. 癌症:体细胞进化中的一个问题。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3701-0_1
J L Collins, P Q Patek, M Cohn
{"title":"Cancer: a problem in somatic cell evolution.","authors":"J L Collins,&nbsp;P Q Patek,&nbsp;M Cohn","doi":"10.1007/978-1-4684-3701-0_1","DOIUrl":"https://doi.org/10.1007/978-1-4684-3701-0_1","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"11 ","pages":"1-79"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17227060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Mononuclear cells and IgG associated with human malignant tissue. 与人类恶性组织相关的单核细胞和IgG。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_7
O Tønder, R Matre, F Wesenberg
{"title":"Mononuclear cells and IgG associated with human malignant tissue.","authors":"O Tønder,&nbsp;R Matre,&nbsp;F Wesenberg","doi":"10.1007/978-1-4684-3677-8_7","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_7","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"167-76"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4684-3677-8_7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18419334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Discrimination of self and non-self in plants. 植物对自我和非自我的辨别
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_1
R B Knox, A E Clarke
{"title":"Discrimination of self and non-self in plants.","authors":"R B Knox, A E Clarke","doi":"10.1007/978-1-4615-9131-3_1","DOIUrl":"10.1007/978-1-4615-9131-3_1","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"9 ","pages":"1-36"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17219214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Tumor immunity in the peritoneal cavity. 腹膜腔肿瘤免疫。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_14
G Berke, B Schick
{"title":"Tumor immunity in the peritoneal cavity.","authors":"G Berke,&nbsp;B Schick","doi":"10.1007/978-1-4684-3677-8_14","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_14","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"297-315"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18016981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Cellular basis for regulation of tumor growth. 肿瘤生长调控的细胞基础。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_12
R Evans
{"title":"Cellular basis for regulation of tumor growth.","authors":"R Evans","doi":"10.1007/978-1-4684-3677-8_12","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_12","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"255-66"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18419336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Evidence for mononuclear phagocytes in solid neoplasms and appraisal of their nonspecific cytotoxic capabilities. 实体肿瘤中单核吞噬细胞存在的证据及其非特异性细胞毒能力的评价。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_6
S W Russell, G Y Gillespie, J L Pace
{"title":"Evidence for mononuclear phagocytes in solid neoplasms and appraisal of their nonspecific cytotoxic capabilities.","authors":"S W Russell,&nbsp;G Y Gillespie,&nbsp;J L Pace","doi":"10.1007/978-1-4684-3677-8_6","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_6","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"143-66"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18419333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 39
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