Complex Metals最新文献_第2页

Synthesis and crystal structure of N-6-[(4-pyridylamino)carbonyl]-pyridine-2-carboxylic acid methyl ester zinc complex N-6-[(4-吡啶氨基)羰基]-吡啶-2-羧酸甲酯锌配合物的合成及晶体结构

Complex Metals Pub Date : 2014-03-17 DOI: 10.1080/2164232X.2014.883289

M. Kadir, N. Mansor, M. Yusof, C. Sumby

引用次数: 9

Preparation and structure of 1RS,4SR,7SR,10RS- (1,4,7,10-tetraazacyclopentadecane)copper(II) tetrachlorozincate 1RS,4SR,7SR,10RS-(1,4,7,10-四氮杂环十五烷)铜(II)四氯辛酸盐的制备与结构

Complex Metals Pub Date : 2014-03-17 DOI: 10.1080/2164232X.2013.868325

N. F. Curtis, J. Wikaira

引用次数: 1

The first 3-fold interpenetrating framework containing both azobenzene-3,3′-dicarboxylicate and 1,2-bis(4-pyridyl)ethylene 第一个含有偶氮苯-3,3 ' -二羧酸和1,2-双(4-吡啶基)乙烯的3倍互穿骨架

Complex Metals Pub Date : 2014-03-17 DOI: 10.1080/2164232X.2013.871620

Ya-Ping Duan, W. Xia, P. Tang, Dong‐sheng Li, W. Dong, Jack Y. Lu

引用次数: 0

The specification of the production of three different complexes via thermodynamic investigations between vanadyl (IV) bis(acetylacetonate) and D-penicillamine at three various pHs 通过热力学研究钒(IV)二乙酰丙酮酸和d -青霉胺在三种不同ph值下的三种不同配合物的生产规范

Complex Metals Pub Date : 2014-03-17 DOI: 10.1080/2164232X.2014.883489

R. Hakimelahi, M. Mousazadeh

{"title":"The specification of the production of three different complexes via thermodynamic investigations between vanadyl (IV) bis(acetylacetonate) and D-penicillamine at three various pHs","authors":"R. Hakimelahi, M. Mousazadeh","doi":"10.1080/2164232X.2014.883489","DOIUrl":"https://doi.org/10.1080/2164232X.2014.883489","url":null,"abstract":"d-H2Pen-binding behavior to [VO(acac)2] at pH=7.00, 7.50 and 10.0 has been studied in thermodynamic viewpoint using UV/VIS spectroscopy. The optical absorption spectra of [VO(acac)2] were analyzed in order to obtain binding constants and stoichiometries using SQUAD software. The estimation of binding constant at various temperatures enabled us to calculate all of the thermodynamic parameters of binding using the van't Hoff equation. Studies of described reactions at pH=7.00, 7.50 and 10.0 show exothermic, endothermic and exothermic modality, respectively. d-penicillamine is a potentially tridentate ligand, but the pKa for the ‒ COOH, NH3 and S‒ H groups are 1.99–2.00, 8.0 and 10.6, respectively, as a result S‒H can not release proton at pH=7.00 and pH=7.50, so the coordination of S is not possible except at strong alkali mediums. At pH=7.00, d-H2Pen converts [VO(acac)2] to a vanadyl Schiff base complex (coordination mode is N2O2). At pH=7.50, d-H2Pen is converted to HPen− and the exchange of acac− with HPen− produces VO(HPen)2. It is clear that the coordination is formed via amine nitrogen and carboxylate oxygen. At pH=10.0, the main product is a vanadyl complex with the (S2O2) coordination mode. Studies in different ionic strengths of KCl confirm these products according to the number of ions in each medium. The formation constants of the products of VO(acac)2 with d-penicillamine at pH=7.00 and 7.50 are independent of ionic strength, but a Debye–Huckel-type equation was established for the dependence of the formation constant on ionic strength at pH=10.0.","PeriodicalId":10590,"journal":{"name":"Complex Metals","volume":"17 1","pages":"52 - 56"},"PeriodicalIF":0.0,"publicationDate":"2014-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88626850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Reactions of Cr3+ with aspartic acid within a wide pH range Cr3+与天冬氨酸在很宽的pH范围内的反应

Complex Metals Pub Date : 2014-03-17 DOI: 10.1080/2164232X.2014.883291

Yahia Z. Hamada, Nabil Bayakly, M. Shafi, S. Painter, Vanessa Taylor, J. Greene, Khalid Rosli

引用次数: 4

Formation of polymeric assemblies of six-coordinate metal complexes with mixed bridges of dicarboxylato-azido moieties 具有二羧基叠氮基团混合桥的六配位金属配合物聚合组合的形成

Complex Metals Pub Date : 2014-03-17 DOI: 10.1080/2164232X.2014.883290

R. Ahmed, T. A. Hamdan, A. Numan, M. J. Al-Jeboori, H. Potgieter

引用次数: 3

Synthesis and characterization of 5-amino-2-((3-hydroxy-4-((3-hydroxyphenyl) phenyl) diazenyl) phenol and its Cu(II) complex – a strategy toward developing azo complexes for reduction of cytotoxicity 5-氨基-2-((3-羟基-4-(3-羟基苯基)苯基)二氮基)苯酚及其Cu(II)配合物的合成与表征——开发偶氮配合物降低细胞毒性的策略

Complex Metals Pub Date : 2014-03-14 DOI: 10.1080/2164232X.2014.883287

Durba Ganguly, Ratul Sarkar, R. Santra, Tathagata Deb, T. Sen, Saurabh Das

{"title":"Synthesis and characterization of 5-amino-2-((3-hydroxy-4-((3-hydroxyphenyl) phenyl) diazenyl) phenol and its Cu(II) complex – a strategy toward developing azo complexes for reduction of cytotoxicity","authors":"Durba Ganguly, Ratul Sarkar, R. Santra, Tathagata Deb, T. Sen, Saurabh Das","doi":"10.1080/2164232X.2014.883287","DOIUrl":"https://doi.org/10.1080/2164232X.2014.883287","url":null,"abstract":"A major drawback of azo compounds is their associated toxicity, often carcinogenic, which is related to the reduction of the azo bond. This study intends to re-investigate this behavior by studying 5-amino-2-((3-hydroxy-4-((3-hydroxyphenyl) phenyl) diazenyl) phenol (AHPD), a compound containing two azo bonds. Interaction of AHPD and its dimeric Cu(II) complex with bacterial strains Escherichia coli and Staphylococcus aureus revealed the complex was less toxic. Reductive cleavage of the azo bond in AHPD and the complex followed using cytochrome c reductase (a model azo-reductase) as well as azo-reductase enzymes obtained from bacterial cell extracts. Degradation of the azo bond was less in the complex allowing us to correlate the observed cytotoxicity. Cyclic voltammetry on AHPD and the complex support observations of enzyme assay experiments. These were particularly useful in realizing the formation of amines as an outcome of the reductive cleavage of azo bonds in AHPD that could not be identified through an enzyme assay. Results suggest that complex formation of azo compounds could be a means to control the formation of amines responsible for cytotoxicity. Studies carried out on bacterial cells for mere simplicity bear significance for multicellular organisms and could be important for human beings involved with the preparation and utilization of azo dyes.","PeriodicalId":10590,"journal":{"name":"Complex Metals","volume":"1 1","pages":"13 - 22"},"PeriodicalIF":0.0,"publicationDate":"2014-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76732997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Ru(II) trithiacyclononane 5-(2-hydroxyphenyl)-3-[(4-methoxystyryl)pyrazole], a complex with facile synthesis and high cytotoxicity against PC-3 and MDA-MB-231 cells 钌(II)三噻吩环壬烷5-(2-羟基苯基)-3-[(4-甲氧基苯基)吡唑]，一种易于合成且对PC-3和MDA-MB-231细胞具有高细胞毒性的配合物

Complex Metals Pub Date : 2014-03-14 DOI: 10.1080/2164232X.2013.873992

J. Marques, Vera L. M. Silva, Artur M. S. Silva, Mario Monteiro Marques, S. Braga

引用次数: 8

Platinum(II)/palladium(II) complexes with n-propyldithiocarbamate and 2,2′-bipyridine: synthesis, characterization, biological activity and interaction with calf thymus DNA 铂(II)/钯(II)配合物与n-丙基二硫氨基甲酸酯和2,2 ' -联吡啶:合成、表征、生物活性及其与小牛胸腺DNA的相互作用

Complex Metals Pub Date : 2014-03-14 DOI: 10.1080/2164232X.2014.883288

H. Mansouri‐Torshizi, S. Shahraki, Z. Nezami, A. Ghahghaei, Sahebeh Najmedini, A. Divsalar, Hamed Ghaemi, A. Saboury

{"title":"Platinum(II)/palladium(II) complexes with n-propyldithiocarbamate and 2,2′-bipyridine: synthesis, characterization, biological activity and interaction with calf thymus DNA","authors":"H. Mansouri‐Torshizi, S. Shahraki, Z. Nezami, A. Ghahghaei, Sahebeh Najmedini, A. Divsalar, Hamed Ghaemi, A. Saboury","doi":"10.1080/2164232X.2014.883288","DOIUrl":"https://doi.org/10.1080/2164232X.2014.883288","url":null,"abstract":"Two Pd(II) and Pt(II) complexes ([Pt(bpy)(pr-dtc)]Br and [Pd(bpy)(pr-dtc)]Br, where bpy=2, 2′-bipyridine and pr-dtc = n-propyldithiocarbamate) were synthesized and characterized by elemental analysis (CHN), molar conductivity measurements, Fourier transform infrared, 1H nuclear magnetic resonance and UV–visible techniques. In these complexes, the dithiocarbamato ligand coordinates to Pt(II) or Pd(II) center as bidentate with two sulfur atoms. The binding of these complexes to calf thymus DNA (CT-DNA) was investigated using various physicochemical methods such as spectrophotometric, spectrofluorometric and gel filtration technique. The experimental results indicate that Pt(II) and Pd(II) complexes interact with CT-DNA in the intercalative mode. Both complexes unexpectedly denatured DNA at low concentration. Gel filtration studies indicated that the binding of complexes with DNA is strong enough and does not break readily. The cytotoxic activity of these metal complexes has been tested against human cell tumor lines (K562) and revealed much lower 50% cytotoxic concentration (Cc50) less than that of cisplatin. Several binding and thermodynamic parameters are also described.","PeriodicalId":10590,"journal":{"name":"Complex Metals","volume":"12 1","pages":"23 - 31"},"PeriodicalIF":0.0,"publicationDate":"2014-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84094594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26