Clinical Microbiology and Infection最新文献

{"title":"Anthropology of infectious disease emergence and epidemic control: a review.","authors":"Tamara Giles-Vernick, Jules Villa","doi":"10.1016/j.cmi.2025.04.019","DOIUrl":"https://doi.org/10.1016/j.cmi.2025.04.019","url":null,"abstract":"<p><strong>Background: </strong>Traditional biomedical and epidemiological approaches have been crucial in preparing for and responding to infectious disease epidemics. But biologists, public health researchers and actors, and global health institutions have increasingly recognized that medical anthropology can contribute to epidemic response. Although medical anthropologists have welcomed their integration into epidemic response, they have simultaneously insisted that an anthropology of epidemics should not be siloed, that is, channelled exclusively into ensuring public acceptance and uptake of epidemic control measures.</p><p><strong>Objectives: </strong>The aim of this narrative review was to present a selection of the medical anthropological contributions to different stages of infectious disease epidemic processes, from zoonotic spillovers to epidemic response and preparedness for future epidemics.</p><p><strong>Sources: </strong>We conducted searches in PubMed and Web of Science on multiple topics through 20 December 2024, including medical anthropological contributions to understanding zoonotic spillovers and epidemic emergences, epidemic response, and epidemic preparedness. We also manually added important publications (monographs and articles not listed in these searches).</p><p><strong>Content: </strong>The review provided concrete evidence of important medical anthropological contributions to literatures on zoonotic spillovers leading to epidemic emergence, epidemic response, and preparedness for future epidemics. We show that medical anthropology can produce substantial insight and propose pragmatic measures to full range of epidemic infectious disease processes.</p><p><strong>Implications: </strong>More than an approach to strengthen public uptake of epidemic control measures, medical anthropology can productively contribute to insight into the full range of epidemic processes. To produce new multidisciplinary insights into epidemic processes, from epidemic emergence to response to preparing for future epidemics, we encourage new collaborations between medical anthropologists and clinical microbiologists.</p>","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusually sore head: Melioidosis case report.","authors":"Adam Hinchcliffe, Chloe Hylton, Kerryanne Brown, Kalani Mortimer, Dilnath Gurusinghe","doi":"10.1016/j.cmi.2025.04.017","DOIUrl":"10.1016/j.cmi.2025.04.017","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pertussis epidemic in Slovenia in 2024-no pertactin-deficient or macrolide-resistant Bordetella pertussis isolates identified.","authors":"Tamara Kastrin, Alex-Mikael Barkoff, Katja Seme, Luka Kosec, Tina Triglav, Nadja Šinkovec Zorko, Mojca Rožič, Jussi Mertsola, Qiushui He","doi":"10.1016/j.cmi.2025.04.016","DOIUrl":"https://doi.org/10.1016/j.cmi.2025.04.016","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: 'Oral switch versus continued intravenous antibiotic therapy in patients with bacteraemia and sepsis' by Li et al.","authors":"Jacob Bodilsen","doi":"10.1016/j.cmi.2025.04.018","DOIUrl":"https://doi.org/10.1016/j.cmi.2025.04.018","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between plasma interferon-γ levels and preeclampsia in pregnant women screened for tuberculosis infection.","authors":"John Walles, Niclas Winqvist, Stefan R Hansson, Erik Sturegård, Haitham Baqir, Torbjörn Kjerstadius, Thomas Schön, Per Björkman","doi":"10.1016/j.cmi.2025.04.015","DOIUrl":"10.1016/j.cmi.2025.04.015","url":null,"abstract":"<p><strong>Objectives: </strong>Pregnancy can influence immune control of Mycobacterium tuberculosis infection (MtbI). We recently reported an association between MtbI and pregnancy complications, particularly severe preeclampsia, in a registry-based cohort of women originating in tuberculosis-endemic countries screened for MtbI in Swedish antenatal care, implying a potential role of MtbI for the development of preeclampsia. Here, we aimed to investigate the role of plasma interferon-γ secretion as a potential mediator of this interaction.</p><p><strong>Methods: </strong>Plasma interferon-γ levels were compared with women with MtbI (defined as positive QuantiFERON results in the absence of tuberculosis) and MtbI-negative women regarding any diagnosis of preeclampsia and severe preeclampsia. Odds of preeclampsia and severe preeclampsia were compared with respect to MtbI status and interferon-γ levels >90th percentile in the study population (0.28 IU/mL).</p><p><strong>Results: </strong>MtbI was detected in 700 of 3605 women (19.4%) and preeclampsia was diagnosed in 110 (3.1%), among whom 50 (1.4%) had severe preeclampsia. Women with MtbI had higher interferon-γ levels than MtbI-negative women (median 0.12 IU/mL, interquartile range [IQR], 0.06-0.26 IU/mL; vs. 0.07 IU/mL, IQR 0.04-0.12 IU/mL; p < 0.001). The prevalence of preeclampsia of any grade (13/159, 8.2%, odds ratio [OR], 2.79; 95% CI, 1.52-5.12; p < 0.001) and severe preeclampsia (10/159, 6.3%, OR, 5.46; 95% CI, 2.64-11.3; p < 0.0001) was higher in women with MtbI and interferon-γ levels >0.28 IU/mL, than in MtbI-negative women with interferon-γ levels <0.28 IU/mL. Neither women with MtbI with interferon-γ levels <0.28 IU/mL, nor MtbI-negative women with interferon-γ levels >0.28 IU/mL, had increased odds of preeclampsia or severe preeclampsia compared to MtbI-negative women with interferon-γ levels <0.28 IU/mL.</p><p><strong>Discussion: </strong>These findings suggest that interferon-γ secretion could be involved as a mediator in the association between MtbI and development of preeclampsia.</p>","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful treatment and secondary prophylaxis with pritelivir for a recurrent multidrug-resistant herpes simplex virus 1 infection in an allogeneic haematopoietic stem cell transplant recipient","authors":"Linda Bussini ,&nbsp;A.M. Federica Giardina ,&nbsp;Stefania Paolucci ,&nbsp;Daniele Mannina ,&nbsp;Alexander Birkmann ,&nbsp;Michele Bartoletti","doi":"10.1016/j.cmi.2025.04.011","DOIUrl":"10.1016/j.cmi.2025.04.011","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":"31 7","pages":"Pages 1234-1236"},"PeriodicalIF":10.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unexpected case of Trichuriasis in North China","authors":"Lijuan Niu ,&nbsp;Sanping Zhang ,&nbsp;Yongqiang Qin ,&nbsp;Guoqiang Yang ,&nbsp;Hairu Wang ,&nbsp;Peixia Yu","doi":"10.1016/j.cmi.2025.04.010","DOIUrl":"10.1016/j.cmi.2025.04.010","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":"31 7","pages":"Pages 1170-1171"},"PeriodicalIF":10.9,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting bacteriology diagnostics: how to make them globally available and accessible.","authors":"Liselotte Hardy, Jan Jacobs, Cédric Yansouni, Dissou Affolabi","doi":"10.1016/j.cmi.2025.04.012","DOIUrl":"10.1016/j.cmi.2025.04.012","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":" ","pages":""},"PeriodicalIF":10.9,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of Truenat MTB Ultima on sputum for pulmonary tuberculosis diagnosis in an HIV-endemic setting","authors":"Shima M. Abdulgader ,&nbsp;Arthur M. Chiwaya ,&nbsp;Welile V. Nwamba ,&nbsp;Byron W.P. Reeve ,&nbsp;Zaida Palmer ,&nbsp;Hridesh Mishra ,&nbsp;Desiree Mbu ,&nbsp;Nondumiso Lushozi ,&nbsp;Zola Nkwanyana ,&nbsp;Morten Ruhwald ,&nbsp;Adam Penn-Nicholson ,&nbsp;Robin Warren ,&nbsp;Grant Theron","doi":"10.1016/j.cmi.2025.04.013","DOIUrl":"10.1016/j.cmi.2025.04.013","url":null,"abstract":"<div><h3>Objectives</h3><div>Assess Truenat MTB Ultima (Ultima) diagnostic accuracy, alongside standard-of-care Truenat MTB Plus (MTB Plus) and Xpert MTB/RIF Ultra (Ultra) tests, for pulmonary tuberculosis (TB) diagnosis in a high-burden setting. We secondarily evaluated Truenat MTB-RIF Dx (MTB-RIF Dx) on Ultima- or MTB Plus-positive samples for rifampicin susceptibility diagnosis.</div></div><div><h3>Methods</h3><div>Adults (≥18 years; <em>n</em> = 498) with presumptive TB self-presenting to primary care clinics in Cape Town, South Africa (19/02/2016-22/02/2023) provided sputa. The microbiological reference standard was a single culture for TB and MTBDR<em>plus</em> on an isolate for rifampicin susceptibility.</div></div><div><h3>Results</h3><div>In total, 54% (<em>n</em> = 269) of the participants had HIV, and 42% (<em>n</em> = 210) had previous TB. The proportion of Ultima and MTB Plus unsuccessful results was 14% (95% CI 11, 16) and 20% (17, 23), respectively, with at least half resolving upon retesting the same eluate. In a three-way analysis, Ultima, MTB Plus, and Ultra had TB sensitivities of 90% (85, 93), 84% (78, 88), and 92% (87, 95) and specificities of 85% (80, 88), 95% (92, 97), and 95% (92, 97). Ultima specificity did not improve with Ultra in the reference standard. MTB-RIF Dx had high unsuccessful result rates that varied if done on the day of DNA extraction or on Ultima- [18% (10, 26) vs. 44% (35, 51) if after day of extraction] or MTB Plus-positive eluates [9% (3, 16) vs. 27% (18, 35)]. Same day rifampicin susceptibility testing was often unsuccessful in samples with the “very low” semiquantitation category reported by Ultima [75% (65, 86)] or MTB Plus [73% (58, 89)] but had 100% (40, 100) sensitivity and 99% (96, 100) specificity (on both MTB Plus- or Ultima-positive DNA). Reagent lot variation in unsuccessful and false positive results was observed.</div></div><div><h3>Discussion</h3><div>Ultima met the minimum sensitivity recommended by the WHO for TB detection, but specificity, reagent lot variation, and unsuccessful results were suboptimal.</div></div>","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":"31 7","pages":"Pages 1203-1209"},"PeriodicalIF":10.9,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of disk diffusion, MIC test strip and broth microdilution methods for eravacycline susceptibility testing","authors":"Yang Yang ,&nbsp;Dandan Yin ,&nbsp;Jie Lin ,&nbsp;Yunfan Zhu ,&nbsp;Yunsong Yu ,&nbsp;Fupin Hu","doi":"10.1016/j.cmi.2025.04.014","DOIUrl":"10.1016/j.cmi.2025.04.014","url":null,"abstract":"","PeriodicalId":10444,"journal":{"name":"Clinical Microbiology and Infection","volume":"31 7","pages":"Pages 1231-1233"},"PeriodicalIF":10.9,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}