Clinical Reviews in Allergy & Immunology最新文献_第10页

Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review. 与静脉注射多克隆免疫球蛋白治疗相关的急性无菌性脑膜炎：系统回顾。

IF 8.4 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-04-01 Epub Date: 2024-05-13 DOI: 10.1007/s12016-024-08989-1

Elisabetta L T De Felice, Gabriel F Toti, Beatrice Gatti, Renato Gualtieri, Pietro Camozzi, Sebastiano A G Lava, Gregorio P Milani, Giorgio Treglia, Federica Vanoni, Mario G Bianchetti, Gianmaria F Bernasconi, Benedetta Terziroli Beretta Piccoli, Camilla Lavagno

{"title":"Acute Aseptic Meningitis Temporally Associated with Intravenous Polyclonal Immunoglobulin Therapy: A Systematic Review.","authors":"Elisabetta L T De Felice, Gabriel F Toti, Beatrice Gatti, Renato Gualtieri, Pietro Camozzi, Sebastiano A G Lava, Gregorio P Milani, Giorgio Treglia, Federica Vanoni, Mario G Bianchetti, Gianmaria F Bernasconi, Benedetta Terziroli Beretta Piccoli, Camilla Lavagno","doi":"10.1007/s12016-024-08989-1","DOIUrl":"10.1007/s12016-024-08989-1","url":null,"abstract":"An acute aseptic meningitis has been occasionally observed on intravenous polyclonal human immunoglobulin therapy. Since case reports cannot be employed to draw inferences about the relationships between immunoglobulin therapy and meningitis, we conducted a systematic review and meta-analysis of the literature. Eligible were cases, case series, and pharmacovigilance studies. We found 71 individually documented cases (36 individuals ≤ 18 years of age) of meningitis. Ninety percent of cases presented ≤ 3 days after initiating immunoglobulin therapy and recovered within ≤ 7 days (with a shorter disease duration in children: ≤ 3 days in 29 (94%) cases). In 22 (31%) instances, the authors noted a link between the onset of meningitis and a rapid intravenous infusion of immunoglobulins. Cerebrospinal fluid analysis revealed a predominantly neutrophilic (N = 46, 66%) pleocytosis. Recurrences after re-exposure were observed in eight (N = 11%) patients. Eight case series addressed the prevalence of meningitis in 4089 patients treated with immunoglobulins. A pooled prevalence of 0.6% was noted. Finally, pharmacovigilance data revealed that meningitis temporally associated with intravenous immunoglobulin therapy occurred with at least five different products. In conclusion, intravenous immunoglobulin may cause an acute aseptic meningitis. The clinical features remit rapidly after discontinuing the medication.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":" ","pages":"241-249"},"PeriodicalIF":8.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11193830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review 儿童嗜酸性粒细胞增多和全身症状药物反应 (DReSS) 的临床表现和诊断：范围界定综述

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-03-11 DOI: 10.1007/s12016-024-08983-7

{"title":"Clinical Presentation and Diagnosis of Drug Reaction with Eosinophilia and Systemic Symptoms (DReSS) in Children: A Scoping Review","authors":"","doi":"10.1007/s12016-024-08983-7","DOIUrl":"https://doi.org/10.1007/s12016-024-08983-7","url":null,"abstract":"<h3>Abstract</h3> Effective treatment of drug reactions with eosinophilia and systemic symptoms (DReSS) requires early diagnosis and close monitoring. Diagnosing DReSS is especially challenging in children due to a low incidence rate, heterogeneous clinical presentation, and a lack of (pediatric) diagnostic criteria and clinical practice guidelines. We performed a scoping review, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, to summarize the clinical presentation and diagnostic process of DReSS in children (aged 0–18 years). Data from 644 individuals showed that DReSS manifests differently in children compared to adults. Children have a higher number of organs involved, including higher rates of cardiac and respiratory involvement compared to adults. Children < 6 years of age appear more prone to develop neurologic symptoms. Conversely, eosinophilia, edema, and kidney involvement are less frequently observed in children. Anti-seizure medications are by far the most common causative drug class, but the range of implicated drugs increases as children get older. This study highlights that children with DReSS not only differ from adults but also that differences exist between children of different ages. As such, there is a need to establish pediatric-specific diagnostic criteria. These efforts will promote earlier diagnosis of DReSS and likely lead to improved clinical care offered to children and their families.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":"167 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140098988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization. 动脉粥样硬化斑块进展和不稳定过程中肥大细胞的细胞和分子机制

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-01-30 DOI: 10.1007/s12016-024-08981-9

Daniel Elieh-Ali-Komi, Ilze Bot, Mónica Rodríguez-González, Marcus Maurer

{"title":"Cellular and Molecular Mechanisms of Mast Cells in Atherosclerotic Plaque Progression and Destabilization.","authors":"Daniel Elieh-Ali-Komi, Ilze Bot, Mónica Rodríguez-González, Marcus Maurer","doi":"10.1007/s12016-024-08981-9","DOIUrl":"10.1007/s12016-024-08981-9","url":null,"abstract":"Mast cells (MCs) are commonly recognized for their crucial involvement in the pathogenesis of allergic diseases, but over time, it has come to light that they also play a role in the pathophysiology of non-allergic disorders including atherosclerosis. The involvement of MCs in the pathology of atherosclerosis is supported by their accumulation in atherosclerotic plaques upon their progression and the association of intraplaque MC numbers with acute cardiovascular events. MCs that accumulate within the atherosclerotic plaque release a cocktail of mediators through which they contribute to neovascularization, plaque progression, instability, erosion, rupture, and thrombosis. At a molecular level, MC-released proteases, especially cathepsin G, degrade low-density lipoproteins (LDL) and mediate LDL fusion and binding of LDL to proteoglycans (PGs). Through a complicated network of chemokines including CXCL1, MCs promote the recruitment of among others CXCR2+ neutrophils, therefore, aggravating the inflammation of the plaque environment. Additionally, MCs produce extracellular traps which worsen inflammation and contribute to atherothrombosis. Altogether, evidence suggests that MCs actively, via several underlying mechanisms, contribute to atherosclerotic plaque destabilization and acute cardiovascular syndromes, thus, making the study of interventions to modulate MC activation an interesting target for cardiovascular medicine.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":" ","pages":"30-49"},"PeriodicalIF":9.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10973084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Global View of Pemphigus: Geographical Variations. 天疱疮的全球视野：地域差异。

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-01-30 DOI: 10.1007/s12016-024-08980-w

Rodolfo Pessato Timóteo, Yago Marcos Pessoa-Gonçalves, José Rodrigues do Carmo Neto, Wellington Francisco Rodrigues, Marcos Vinícius da Silva, Carlo José Freire Oliveira

{"title":"A Global View of Pemphigus: Geographical Variations.","authors":"Rodolfo Pessato Timóteo, Yago Marcos Pessoa-Gonçalves, José Rodrigues do Carmo Neto, Wellington Francisco Rodrigues, Marcos Vinícius da Silva, Carlo José Freire Oliveira","doi":"10.1007/s12016-024-08980-w","DOIUrl":"10.1007/s12016-024-08980-w","url":null,"abstract":"Pemphigus, an autoimmune intraepidermal bullous disease group with roughly eight distinct forms, includes pemphigus vulgaris (PV) and pemphigus foliaceus (PF) as its predominant global forms. Despite the increased utilization of global health records and reporting systems, epidemiological data remain limited and poorly categorized. Therefore, this study aimed to conduct a review to track, identify, and characterize cases of PV and PF published and categorized worldwide. A research question was formulated; studies were selected based on the inclusion criteria; and data from these publications were systematically collected, summarized, and presented using narrative descriptions. The search strategy yielded 3,212 articles, of which 95 underwent critical analysis and data extraction. Studies from 52 countries contributed to the dataset, covering various pemphigus variants. Notably, only two countries, Iran (18.87%) and South Korea (11.43%), accounted for approximately a third of the reported PV cases, while Brazil contributed 40.25% of the foliaceus variants cases documented in the literature. These findings offer valuable insights into the global distribution of pemphigus and inform future research and healthcare efforts.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":" ","pages":"14-29"},"PeriodicalIF":9.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139575380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies. 增进对儿童哮喘的了解：从出生队列研究中吸取经验教训。

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-02-07 DOI: 10.1007/s12016-024-08979-3

Yuhan Xing, Xinmeng Yang, Zhaoyinqian Li, Qiyuan Zou, Ping Yang, Qinzheng Wang, Wei Ni, Dongze Wu, Guoju Li

{"title":"Advancing Understanding of Childhood Asthma: Lessons Learned from Birth Cohort Studies.","authors":"Yuhan Xing, Xinmeng Yang, Zhaoyinqian Li, Qiyuan Zou, Ping Yang, Qinzheng Wang, Wei Ni, Dongze Wu, Guoju Li","doi":"10.1007/s12016-024-08979-3","DOIUrl":"10.1007/s12016-024-08979-3","url":null,"abstract":"Asthma and allergies are some of the most common chronic disorders affecting children, the prevalence of which has been increasing in countries and regions undergoing rapid development like China. To curb the rising tide of allergies and safeguard the health of future generations, it is of critical importance to understand how asthma inception is influenced by factors acting at different life stages. Birth cohorts represent a powerful tool to investigate the temporal sequence of exposures along the natural course of asthma. We examined recent evidence on birth cohort studies of asthma and allergic diseases and evaluated their strengths and weaknesses. Essential elements for a successful birth cohort are proposed to further elucidate asthma etiology and pathogenies. Initiating new cohorts in understudied populations with the application of advanced analytical approaches will be needed. Moreover, fostering collaborative networks using standardized methodologies should be prioritized to enable integration of findings across diverse cohorts. There remains an urgent and unmet need to further translate the seminal findings from asthma birth cohort studies into targeted primary prevention strategies to eradicate the disease.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":" ","pages":"50-63"},"PeriodicalIF":9.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Markers of Endothelial Dysfunction in Kawasaki Disease: An Update. 川崎病内皮功能障碍的标志物：最新进展。

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-03-11 DOI: 10.1007/s12016-024-08985-5

Rajni Kumrah, Taru Goyal, Amit Rawat, Surjit Singh

引用次数: 0

B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases. B 细胞受体汇集：自身免疫性疾病的最新进展》。

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-03-09 DOI: 10.1007/s12016-024-08984-6

Qian Wang, Delong Feng, Sujie Jia, Qianjin Lu, Ming Zhao

{"title":"B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases.","authors":"Qian Wang, Delong Feng, Sujie Jia, Qianjin Lu, Ming Zhao","doi":"10.1007/s12016-024-08984-6","DOIUrl":"10.1007/s12016-024-08984-6","url":null,"abstract":"In the field of contemporary medicine, autoimmune diseases (AIDs) are a prevalent and debilitating group of illnesses. However, they present extensive and profound challenges in terms of etiology, pathogenesis, and treatment. A major reason for this is the elusive pathophysiological mechanisms driving disease onset. Increasing evidence suggests the indispensable role of B cells in the pathogenesis of autoimmune diseases. Interestingly, B-cell receptor (BCR) repertoires in autoimmune diseases display a distinct skewing that can provide insights into disease pathogenesis. Over the past few years, advances in high-throughput sequencing have provided powerful tools for analyzing B-cell repertoire to understand the mechanisms during the period of B-cell immune response. In this paper, we have provided an overview of the mechanisms and analytical methods for generating BCR repertoire diversity and summarize the latest research progress on BCR repertoire in autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), primary Sjögren's syndrome (pSS), multiple sclerosis (MS), and type 1 diabetes (T1D). Overall, B-cell repertoire analysis is a potent tool to understand the involvement of B cells in autoimmune diseases, facilitating the creation of innovative therapeutic strategies targeting specific B-cell clones or subsets.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":" ","pages":"76-98"},"PeriodicalIF":9.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140064953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis? 食物引发的特应性皮炎是全身接触性皮炎的一种形式吗？

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-01-29 DOI: 10.1007/s12016-023-08977-x

Kripa Ahuja, Christopher J Issa, Susan T Nedorost, Peter A Lio

{"title":"Is Food-Triggered Atopic Dermatitis a Form of Systemic Contact Dermatitis?","authors":"Kripa Ahuja, Christopher J Issa, Susan T Nedorost, Peter A Lio","doi":"10.1007/s12016-023-08977-x","DOIUrl":"10.1007/s12016-023-08977-x","url":null,"abstract":"Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the microbiome. When contact between inflamed skin and food antigens occurs, contact hypersensitivity can develop. Consequently, systemic contact dermatitis (SCD) can occur after ingestion of allergenic foods or food additives in the setting of a Th2 response with CLA-positive T cells, triggering dermatitis where skin resident memory lymphocytes reside. This phenomenon explains food-triggered dermatitis. Atopy patch tests (APTs) detect sensitization to food proteins responsible for SCD, which in turn can be confirmed by oral food challenge with delayed interpretation. We summarize the literature on using APTs to identify foods for oral challenge with dermatitis as an outcome. In dermatitis patients at risk for Th2 skewing based on a history of childhood-onset flexural dermatitis, shared decision-making should include a discussion of identifying and avoiding food and food additive triggers, as well as identifying and avoiding all contact allergens, prior to initiation of systemic therapy for dermatitis.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":" ","pages":"1-13"},"PeriodicalIF":9.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139569764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tissue-Resident Memory T Cells in Allergy. 过敏症中的组织驻留记忆 T 细胞

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2024-02-01 Epub Date: 2024-02-21 DOI: 10.1007/s12016-024-08982-8

Bojin Long, Shican Zhou, Yawen Gao, Kai Fan, Ju Lai, Chunyan Yao, Jingwen Li, Xiayue Xu, Shaoqing Yu

引用次数: 0

Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis 肿瘤坏死因子α抑制剂与类风湿关节炎的心血管风险

IF 9.1 2区医学

Clinical Reviews in Allergy & Immunology Pub Date : 2023-12-29 DOI: 10.1007/s12016-023-08975-z

Nicoletta Luciano, Elisa Barone, Suraj Timilsina, M. Eric Gershwin, Carlo Selmi

{"title":"Tumor Necrosis Factor Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis","authors":"Nicoletta Luciano, Elisa Barone, Suraj Timilsina, M. Eric Gershwin, Carlo Selmi","doi":"10.1007/s12016-023-08975-z","DOIUrl":"https://doi.org/10.1007/s12016-023-08975-z","url":null,"abstract":"Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an increased risk of cardiovascular events, due to the complex interplay between traditional and disease-related risk factors. Chronic inflammation and persistent disease activity are the key determinants of this risk, but despite great improvement in the disease management and prognosis, cardiovascular events are still the main cause of morbidity and mortality in RA cohorts1. In the last decades, the advent of new biological and targeted-synthetic DMARDs was accompanied by an improvement in disease activity control, but the role of each class of drugs on CVD risk is still a matter a debate. Since their approval for RA treatment, tumor necrosis factor alpha (TNFα) inhibitors have been widely investigated to better understand their effects on cardiovascular outcomes. The hypothesis that the reduction of chronic inflammation with any treatment may reduce the cardiovascular risk has been recently confuted by the direct comparison of TNFα-inhibitors and JAK inhibitors in patients with RA and coexisting risk factors for cardiovascular disease. The aim of this literature review is to add to the available evidence to analyze the relationship between TNFα-inhibitors and CVD risk in patients with RA and also provide some clinical scenarios to better explain the treatment dilemmas. In particular, while data on major cardiovascular events and thromboembolism seem consistent with an inflammation-mediated benefit with TNFα-inhibitors, there remain concerns about the use of this class of bDMARDs in patients with chronic heart failure.","PeriodicalId":10423,"journal":{"name":"Clinical Reviews in Allergy & Immunology","volume":"1 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139064887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0