Clinical and Experimental Nephrology最新文献_第2页

Assessment of communication environment and health literacy of patients on chronic hemodialysis: a multicenter observational study (SMEL-HD study). 评估慢性血液透析患者的沟通环境和健康素养：一项多中心观察研究（SMEL-HD 研究）。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI: 10.1007/s10157-024-02572-w

Chieko Hamada, Junko Kuwamura, Mitsumine Fukui, Isao Ohsawa, Yuuya Nakamura, Shigenobu Suzuki, Fukuji Takeda, Reo Kanda, Atsuko Urita, Yasuhiko Tomino

{"title":"Assessment of communication environment and health literacy of patients on chronic hemodialysis: a multicenter observational study (SMEL-HD study).","authors":"Chieko Hamada, Junko Kuwamura, Mitsumine Fukui, Isao Ohsawa, Yuuya Nakamura, Shigenobu Suzuki, Fukuji Takeda, Reo Kanda, Atsuko Urita, Yasuhiko Tomino","doi":"10.1007/s10157-024-02572-w","DOIUrl":"10.1007/s10157-024-02572-w","url":null,"abstract":"Background: The ability to access health and medical information have implications for prognosis and quality of life. This study investigated the current communication environment and health literacy in chronic hemodialysis (HD) patients and their associations with patients' physical condition and clinical findings.Methods: This was a cross-sectional, single-arm, multicenter exploratory study. Data were collected from 211 patients (64 males) undergoing chronic HD at five facilities. This included a survey of communication environments, health literacy, dialysis management information, and clinical findings.Results: Among the participants, 145 (68.7%) reported using the Internet. They primarily collected health-related as well as everyday life information through the Internet. Health literacy fell within the problematic range. In terms of e-Health literacy, \"understanding\" and \"easy\" showed a positive trend, while \"accessing,\" \"appraising,\" and \"applying\" were perceived as \"difficult.\" Three groups were identified based on Internet usage: good communication environment (CE) group (134 participants), poor-CE group (56 participants), and a group that did not respond (21 participants). Grip strength, serum albumin level, and \"information acquisition\" were significantly lower in the poor-CE group. Health literacy increases as the duration of dialysis extends, and decreases with advancing age.Conclusions: Patients who used the Internet gained a wide range of information, including health-related information, for their daily lives. The use of ICT is lower among patients with decreased physical activity, and further investigation is desired into how actively encouraging these patients to collect health information via the Internet can enhance their health literacy.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"322-331"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recovery time is associated with the onset of cardiovascular disease in Japanese patients undergoing maintenance hemodialysis. 在接受维持性血液透析的日本患者中，恢复时间与心血管疾病的发病有关。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-10-31 DOI: 10.1007/s10157-024-02579-3

Takaaki Nawano, Kazunobu Ichikawa, Tsuneo Konta, Ikuto Masakane, Masafumi Watanabe

{"title":"Recovery time is associated with the onset of cardiovascular disease in Japanese patients undergoing maintenance hemodialysis.","authors":"Takaaki Nawano, Kazunobu Ichikawa, Tsuneo Konta, Ikuto Masakane, Masafumi Watanabe","doi":"10.1007/s10157-024-02579-3","DOIUrl":"10.1007/s10157-024-02579-3","url":null,"abstract":"Introduction: Cardiovascular disease (CVD) is the leading cause of mortality in patients undergoing maintenance hemodialysis (HD), with various reported risk factors. Recovery time (RT) is a valuable indicator of post-dialysis fatigue. However, the association between RT and the onset of CVD remains unexplored. As such, this study aimed to determine the effect of RT on the onset of CVD.Methods: Data from 620 patients undergoing maintenance HD at Yabuki Hospital and 3 related facilities (Yamagata Prefecture, Japan) as of December 31, 2020, were retrospectively analyzed. Patients were asked to respond to the question \"How long does it take you to recover from a dialysis session?\"; the response was defined as RT. The analysis was performed by categorizing patients into 2 groups according to RT: short RT (< 2 h); and long RT (≥ 2 h). The primary outcome was major adverse cardiovascular events (MACE). Secondary outcomes included all-cause death and hospitalization.Results: During the 24-month follow-up, 70 (11.3%) patients developed MACE. The long RT group exhibited a higher incidence of MACE; multivariate analysis revealed that age and long RT were associated with the onset of MACE. All-cause death was observed in 45 (7.3%) patients, with no significant difference between the 2 groups. Hospitalization occurred in 252 (40.6%) patients and was more frequent in the long RT group. Multivariate analysis revealed that age, sex, duration of HD, intact parathyroid hormone level, and long RT were associated with hospitalization.Conclusion: Long RT was an independent risk factor for the onset of CVD.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"342-349"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adolescents and parents' knowledge of chronic kidney disease: the potential of school-based education. 青少年和家长对慢性肾脏病的认识：校本教育的潜力。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-10-29 DOI: 10.1007/s10157-024-02574-8

Junko Nakamura, Ryohei Kaseda, Mizuki Takeuchi, Kou Kitabayashi, Ichiei Narita

{"title":"Adolescents and parents' knowledge of chronic kidney disease: the potential of school-based education.","authors":"Junko Nakamura, Ryohei Kaseda, Mizuki Takeuchi, Kou Kitabayashi, Ichiei Narita","doi":"10.1007/s10157-024-02574-8","DOIUrl":"10.1007/s10157-024-02574-8","url":null,"abstract":"Background: Preventing the progression of chronic kidney disease (CKD), reducing the incidence of new dialysis patients, and increasing public awareness about CKD are pivotal in mitigating renal impairment. This study aimed to assess the relevance of kidney disease and CKD knowledge among junior high school students and their parents.Methods: A questionnaire survey on kidney function and CKD was conducted among students aged 14-15 years and their parents (851 pairs). Parents were also asked about their age, sex, and participation in health checkups.Results: The study achieved a collection rate of 49.1%, with a valid response rate of 79.7%. Both junior high school students and their parents exhibited limited knowledge about kidney functions, primarily understanding these functions only in terms of waste product excretion and lacking awareness of other functions. A significant positive correlation was observed in awareness of kidney functions between students and their parents. Regarding CKD awareness, only 2.4% of students and 16.5% of parents were knowledgeable about CKD itself, while 18.9% of students and 45.3% of parents were aware of its name only. Importantly, CKD knowledge among both students and parents was associated, with those aware of CKD also demonstrating better understanding of kidney functions.Conclusion: This study highlights inadequate knowledge among junior high school students and their parents regarding renal function and CKD. A significant correlation was observed in CKD awareness between students and their parents. These findings underscore the need for targeted strategies to enhance public education and awareness about kidney health.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"292-300"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for chronic kidney disease in Japanese infants with solitary functioning kidney. 日本孤立肾功能婴儿慢性肾脏疾病的危险因素

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2025-01-04 DOI: 10.1007/s10157-024-02622-3

Toshimasa Morishita, Shuichiro Fujinaga

引用次数: 0

Chloride removal and bicarbonate replacement by isotonic sodium bicarbonate-based continuous hemodiafiltration: a novel method to correct severe metabolic acidosis. 以等渗碳酸氢钠为基础的持续血液渗滤法去除氯化物并补充碳酸氢盐：纠正严重代谢性酸中毒的新方法。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-11-27 DOI: 10.1007/s10157-024-02555-x

Yoshihiro Inoue, Yayoi Tsuchihashi, Hassu Kin, Masaaki Nakayama, Yasuhiro Komatsu

{"title":"Chloride removal and bicarbonate replacement by isotonic sodium bicarbonate-based continuous hemodiafiltration: a novel method to correct severe metabolic acidosis.","authors":"Yoshihiro Inoue, Yayoi Tsuchihashi, Hassu Kin, Masaaki Nakayama, Yasuhiro Komatsu","doi":"10.1007/s10157-024-02555-x","DOIUrl":"10.1007/s10157-024-02555-x","url":null,"abstract":"Background: Previous reports highlighted the efficacy of hemofiltration utilizing isotonic sodium bicarbonate solution as replacement fluid for severe metabolic acidosis. This approach corrects metabolic acidosis by eliminating chloride and supplementing bicarbonate. Here, we present the results of an in vitro study aimed at determining the effect of Isotonic sodium bicarbonate-based Continuous HemoDiafiltration (IBB-CHDF).Methods: Conventional Continuous HemoDiaFiltration (CHDF) and IBB-CHDF utilized aqueous solutions mimicking blood's electrolyte composition. To assess the efficacy and safety, we compared serial changes in pH, HCO3-, Na+, and K+ concentrations. Blood flow rate was 100 mL/min, and the dialysis fluid flow rate maintained 1.0 L/h for both CHDF and IBB-CHDF. Replacement flow rates ranged from 0.5 to 1.5 L/h for CHDF and 0.1 to 1.5 L/h for IBB-CHDF.Results: At a replacement flow rate of 0.5 L/h with IBB-CHDF, bicarbonate increased from 14.7 mEq/L to within the physiological range (25.9 mEq/L), whereas in conventional CHDF, the post-treatment bicarbonate concentration did not increase (16.5 mEq/L). The maximum bicarbonate concentration achieved was 22.0 mEq/L at a replacement flow rate of 1.5 L/h in conventional CHDF. Notably, in IBB-CHDF, the sodium concentration remained constant at 150 mEq/L, 10 mEq/L higher than conventional CHDF, and did not escalate despite increasing the replacement flow rate.Conclusion: IBB-CHDF effectively corrects metabolic acidosis without inducing sodium and water overload by eliminating excess chloride while providing bicarbonate.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"316-321"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phase angle variability on bleeding risks in hemodialysis patients. 相角变化对血液透析患者出血风险的影响。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-10-15 DOI: 10.1007/s10157-024-02577-5

Masayuki Ohta, Toshiro Kan, Yuichi Yoshida, Hiroki Sato, Takuma Hoshino, Tadanao Sato, Yutaka Hoshino

{"title":"Phase angle variability on bleeding risks in hemodialysis patients.","authors":"Masayuki Ohta, Toshiro Kan, Yuichi Yoshida, Hiroki Sato, Takuma Hoshino, Tadanao Sato, Yutaka Hoshino","doi":"10.1007/s10157-024-02577-5","DOIUrl":"10.1007/s10157-024-02577-5","url":null,"abstract":"Background: This study investigated the association between Phase Angle (PhA), measured by bioelectrical impedance analysis, and bleeding risk in hemodialysis patients to evaluate PhA as a predictive marker for bleeding events.Methods: This retrospective cohort study included 102 hemodialysis patients who underwent PhA measurements between July 2019 and April 2024. Demographic data, medical histories, dialysis parameters, and bleeding events were collected. Patients were stratified by PhA values and followed for a median of 832 days (IQR: 516-1304 days). Multivariate Cox proportional hazards regression and Kaplan-Meier analysis were performed.Results: The cohort had an average age of 74.0 years and a median dialysis vintage of 6.7 years. During follow-up, 19 patients (18.6%) experienced major bleeding events. Lower PhA was an independent risk factor for bleeding (HR: 0.24, 95% CI 0.11-0.52, p < 0.001). Kaplan-Meier analysis showed that patients with PhA ≥ 4.00 had a higher probability of remaining free from major bleeding at 2 years (94.3%) compared to those with PhA < 4.00 (75.0%) (p < 0.001). In 82 patients with repeat PhA measurements, bleeding event-free rates at 2 years were 97.5%, 75%, 100%, and 78.3% for the High to High, High to Low, Low to High, and Low to Low groups, respectively (p < 0.001).Conclusion: PhA is a predictive marker for bleeding risk in hemodialysis patients. Routine PhA monitoring could help stratify bleeding risk and optimize clinical management.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"332-341"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk factors for septic shock in older patients with urinary tract infection. 老年尿路感染患者出现脓毒性休克的风险因素。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-11-25 DOI: 10.1007/s10157-024-02563-x

Takaaki Tsuchiya, Kenta Taito, Yui Ota, Shiho Matsuno, Noriko Yamanaka, Masatoshi Oka, Noriyuki Suzuki, Mitsuyo Itabashi, Takashi Takei

{"title":"Risk factors for septic shock in older patients with urinary tract infection.","authors":"Takaaki Tsuchiya, Kenta Taito, Yui Ota, Shiho Matsuno, Noriko Yamanaka, Masatoshi Oka, Noriyuki Suzuki, Mitsuyo Itabashi, Takashi Takei","doi":"10.1007/s10157-024-02563-x","DOIUrl":"10.1007/s10157-024-02563-x","url":null,"abstract":"Backgrounds: Few studies have addressed the risk factors for the development of septic shock in older patients with urinary tract infections. We decided to investigate whether a similar risk exists in in older patients.Methods: A total of 1478 older patients (492 men, 986 women) aged 65 years or older (mean age 85.1 years) who were hospitalized and treated for urinary tract infections were included in this study, and factors contributing to the development of septic shock in these patients, including in terms of the causative pathogens and treatments employed, were investigated through a retrospective review of the patients' medical charts.Results: Underlying urinary tract infection with urolithiasis was found as the most significant risk factor for the development of septic shock (p < 0.01). Patients with urolithiasis were more frail, had higher urinary pH and calcium levels, and showed a higher frequency of infections caused by antimicrobial-resistant and rare bacteria. Cluster analysis revealed a higher incidence of death, septic shock, urolithiasis, and frailty in the patient group treated with carbapenem and/or MRSA agents.Conclusion: Septic shock was associated with a high risk of death in older patients with urinary tract infections, and urolithiasis was identified as an independent risk factor for the development of septic shock. Urolithiasis was also associated with frailty, suggesting that prevention of frailty may indirectly improve the prognosis of patients with septic shock secondary to urinary tract infections.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"368-375"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of hyponatremia: comprehension and best clinical practice.

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2025-01-23 DOI: 10.1007/s10157-024-02606-3

Hirofumi Sumi, Naoto Tominaga, Yoshiro Fujita, Joseph G Verbalis

引用次数: 0

The risk of chronic kidney disease or proteinuria with long or short sleep duration: a systematic review and meta-analysis of cohort studies. 睡眠时间长或短导致慢性肾病或蛋白尿的风险：队列研究的系统回顾和荟萃分析。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2024-10-23 DOI: 10.1007/s10157-024-02575-7

Meng Hu, Yongchong Wang, Wen Zhu, Xiaozhen Chen

{"title":"The risk of chronic kidney disease or proteinuria with long or short sleep duration: a systematic review and meta-analysis of cohort studies.","authors":"Meng Hu, Yongchong Wang, Wen Zhu, Xiaozhen Chen","doi":"10.1007/s10157-024-02575-7","DOIUrl":"10.1007/s10157-024-02575-7","url":null,"abstract":"Objective: Irregular sleep duration has been linked with systemic diseases as well as chronic kidney disease (CKD). However, most of the evidence is low-quality and from cross-sectional data. We hereby present a meta-analysis of cohort studies examining the longitudinal association between short and long sleep with the risk of CKD or proteinuria.Methods: Databases of Embase, PubMed, CENTRAL, Web of Science, and Scopus were searched up to 5th April 2024. The risk of CKD/proteinuria was assessed with short or long sleep duration.Results: Nine studies were included. Both short and long sleep duration were associated with a mild increase in the risk of CKD/proteinuria. Based on different cutoffs for short sleep, we noted that sleep of ≤ 7 h was not associated with a significantly increased risk of CKD/proteinuria. A mild significant risk was noted in the subgroup of ≤ 6 h while a significant association was noted for sleep ≤ 5 h. For longer sleep duration, individuals with ≥ 8 h of sleep had an increased risk of CKD/proteinuria. However, the results were non-significant for individuals with ≥ 9 h of sleep. Non-significant results were noted for separate analyses on male, female, high body mass index, and elderly (≥ 60 years) individuals.Conclusion: Both short and long sleep durations are associated with a significant increase in the risk of CKD/proteinuria in the adult population.","PeriodicalId":10349,"journal":{"name":"Clinical and Experimental Nephrology","volume":" ","pages":"301-315"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Kidney lesions and risk of cardiovascular events in biopsy-proven diabetic kidney disease with type 2 diabetes. 修正：活组织检查证实的糖尿病肾病合并2型糖尿病的肾脏病变和心血管事件的风险。

IF 2.2 4区医学

Clinical and Experimental Nephrology Pub Date : 2025-03-01 Epub Date: 2025-01-09 DOI: 10.1007/s10157-024-02611-6

Miho Shimizu, Kengo Furuichi, Tadashi Toyama, Masayuki Yamanouchi, Daiki Hayashi, Akihiko Koshino, Keisuke Sako, Keisuke Horikoshi, Takahiro Yuasa, Akira Tamai, Taichiro Minami, Megumi Oshima, Shiori Nakagawa, Shinji Kitajima, Ichiro Mizushima, Akinori Hara, Norihiko Sakai, Kiyoki Kitagawa, Mitsuhiro Yoshimura, Junichi Hoshino, Yoshifumi Ubara, Yasunori Iwata, Takashi Wada

引用次数: 0