Clinical Case Studies and Reports最新文献_第7页

A snake bite case: The value of timely diagnosis and treatment 一例蛇咬伤:及时诊断和治疗的价值

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000131

Shimaa M. Motawei

引用次数: 0

A rare cause of abdominal pain: Renal calix rupture 引起腹痛的罕见原因:肾盏破裂

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000113

Murat Muratoglu, C. Kavalci, A. Kayipmaz, C. Akpinar

引用次数: 0

6-methoxy-8-[[6-methoxy-8-[[6-methoxy-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-yl]oxy]-2-methyl-1-(2-methylpropyl)-3,4-dihydro-1h-isoquinolin-7-ol time-resolved absorption and resonance ft-ir and raman biospectroscopy a

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000126

A. Heidari, J. Esposito, Angela Caissutti

引用次数: 6

Simultaneous associated onset of atrial fibrillation and ventricular tachycardia without structural cardiopathy - A case report 无结构性心脏病的心房颤动和室性心动过速同时发病1例

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000122

Eduardo an-Zubero, C. García-Muro, M. Alatorre-Jiménez, A. Marín-Medina, C. López-García, A. Youssef, R. Villeda-González

引用次数: 0

Femoral implant screwed on the lateral femoral shaft 股骨内固定钉在股外侧轴上

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000124

Y. Cirotteau

引用次数: 0

Coexistence of protein C deficiency and prothrombin gene mutation causing neonatal thrombosis 蛋白C缺乏和凝血酶原基因突变共存导致新生儿血栓形成

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000121

K. Acharyya, S. Acharyya

引用次数: 0

Diphtheria toxin time-resolved absorption and resonance ft-ir and raman biospectroscopy and density functional theory (dft) investigation of vibronic-mode coupling structure in vibrational spectra analysis: a spectroscopic study on an anti-cancer drug 白喉毒素时间分辨吸收与共振ft-ir和拉曼生物光谱及密度泛函理论(dft)研究振动光谱分析中的振动模式耦合结构:一种抗癌药物的光谱研究

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000129

A. Heidari, J. Esposito, Angela Caissutti

{"title":"Diphtheria toxin time-resolved absorption and resonance ft-ir and raman biospectroscopy and density functional theory (dft) investigation of vibronic-mode coupling structure in vibrational spectra analysis: a spectroscopic study on an anti-cancer drug","authors":"A. Heidari, J. Esposito, Angela Caissutti","doi":"10.15761/ccsr.1000129","DOIUrl":"https://doi.org/10.15761/ccsr.1000129","url":null,"abstract":"Diphtheria toxin is an exotoxin secreted by Corynebacterium diphtheriae, the pathogenic bacterium that causes diphtheria. Unusually, the toxin gene is encoded by a bacteriophage (a virus that infects bacteria). The toxin causes the disease in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis. Parameters such as FT -IR and Raman vibrational wavelengths and intensities for single crystal Diphtheria Toxin are calculated using density functional theory and were compared with empirical results. The investigation about vibrational spectrum of cycle dimers in crystal with carboxyl groups from each molecule of acid was shown that it leads to create Hydrogen bonds for adjacent molecules. The current study aimed to investigate the possibility of simulating the empirical values. Analysis of vibrational spectrum of Diphtheria Toxin is performed based on theoretical simulation and FT-IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of HF/6-31G*, HF/6-31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6-31++G**, B3LYP/6-31G and B3LYP6-31HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. The obtained values confirm high accuracy and validity of results obtained from calculations.","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78384502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 45

Satisfactory use of high flow nasal cannula in a patient with acute pulmonary embolism 高流量鼻插管在急性肺栓塞患者中的满意应用

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000114

D. Velasco-Álvarez, Javier Pozas Pérez, S. Díaz-Lobato

引用次数: 1

Relationship between symptoms of dyspnea, cough and chromosomal imbalance 呼吸困难、咳嗽症状与染色体失衡的关系

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000119

O. Demirhan, S. Kuleci, Oya Baydar

{"title":"Relationship between symptoms of dyspnea, cough and chromosomal imbalance","authors":"O. Demirhan, S. Kuleci, Oya Baydar","doi":"10.15761/ccsr.1000119","DOIUrl":"https://doi.org/10.15761/ccsr.1000119","url":null,"abstract":"Objectives: Genetic instability is one of the basic reasons for the survival. In this study, a very high genetic imbalance that is inconsistent with cough and life can not be explained with our current genetic information. Materials and methods: We performed cytogenetic analysis by G-banding in an adult girl, aged 23 years, with hundreds of chromosomal abnormalities (CAs). While she has been evaluating for diffuse parenchymal lung disease (DPLD), was considered to have a possible genetic disorder. Results: We observed that there was at least one or more structural and/or numerical CAs in a cell of a person. The numerical and structural aberrations were found in 94.3% of cells analyzed. These CAs were a very serious and very important genetic instability. However, these hundreds of CAs had reflected to clinic appearence with the symptom of dyspnea, cough for the last 5 months, atypical facial and growth retardation. Conclusion: There is a relationship between chromosome damage and symptoms of dyspnea, cough. We are in an inappropriate situation with normal mitosis. It needs to be investigated and explained. *Correspondence to: Osman Demirhan, Department of Medical Biology and Genetics, Faculty of Medicine, Çukurova University, 01330 Balcalı-Adana, Turkey, Tel: 903223387140, Fax: 90-322-3386572, E-mail: osdemir@cu.edu.tr","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77457439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heparin induced thrombocytopenia: A case-based re-appraisal 肝素诱导的血小板减少症:一个基于病例的重新评估

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000120

A. Kandoria, S. Rao, P. Negi, R. Bhardwaj, K. Mahajan, N. Gaur

{"title":"Heparin induced thrombocytopenia: A case-based re-appraisal","authors":"A. Kandoria, S. Rao, P. Negi, R. Bhardwaj, K. Mahajan, N. Gaur","doi":"10.15761/ccsr.1000120","DOIUrl":"https://doi.org/10.15761/ccsr.1000120","url":null,"abstract":"Heparin‐induced thrombocytopenia (HIT) is an immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin. Despite thrombocytopenia, bleeding is rare. HIT is strongly associated with thromboembolic complications involving both the arterial and venous systems. A number of laboratory tests are available to confirm the diagnosis; however, when HIT is clinically suspected, treatment should not be withheld pending the result. Fortunately, therapeutic strategies have been refined, and new and effective therapeutic agents are available. We present a case of HIT Type II. A review of HIT is presented, examining the important clinical symptoms and diagnostic indicators. The treatment of HIT is then discussed, with an emphasis on current therapies. An extensive literature review has been performed to present a comprehensive review of the causes, pathophysiology and treatment of HIT. *Correspondence to: Somendra Rao, MD Senior Resident, Department of Cardiology Indira Gandhi Medical College, Shimla, India, E-mail: sureshdev. rao@gmail.com Received: March 07, 2019; Accepted: March 26, 2019; Published: March 28, 2019 Introduction There are two types of HIT described. Type I is a non-immune, mediated, asymptomatic, transient drop in platelet count that occurs in some heparin treated patients. It is typically characterized by a lesser fall in platelet count within the first two days after heparin initiation and often returns to normal with continued heparin administration [1,2]. Type II (HIT-II) is an immune-mediated disorder characterized by the formation of antibodies against heparin-platelet factor 4 complexes. Since The frequency of HIT varies from 0.5% to 5%, depending on the patient population studied [3]. A meta-analysis noted an incidence of 2.6 percent [4]. It has recently been proposed that the term “HIT type I” be changed to “non‐immune heparin associated thrombocytopenia” and that the term “HIT type II” be changed to “HIT” to avoid confusion between the two syndromes","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73915183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0