Clinical Case Studies and Reports最新文献_第8页

Simple bone cyst in the calcaneus. About a case 跟骨单纯性骨囊肿。关于一个案例

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000134

C. González-Martín, Pilar Bolsa-Col, A. Mosquera-Fernandez, V. Balboa-Barreiro, Daniel Gulias-Soidan

引用次数: 0

Heparin induced thrombocytopenia: A case-based re-appraisal 肝素诱导的血小板减少症:一个基于病例的重新评估

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000120

A. Kandoria, S. Rao, P. Negi, R. Bhardwaj, K. Mahajan, N. Gaur

{"title":"Heparin induced thrombocytopenia: A case-based re-appraisal","authors":"A. Kandoria, S. Rao, P. Negi, R. Bhardwaj, K. Mahajan, N. Gaur","doi":"10.15761/ccsr.1000120","DOIUrl":"https://doi.org/10.15761/ccsr.1000120","url":null,"abstract":"Heparin‐induced thrombocytopenia (HIT) is an immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin. Despite thrombocytopenia, bleeding is rare. HIT is strongly associated with thromboembolic complications involving both the arterial and venous systems. A number of laboratory tests are available to confirm the diagnosis; however, when HIT is clinically suspected, treatment should not be withheld pending the result. Fortunately, therapeutic strategies have been refined, and new and effective therapeutic agents are available. We present a case of HIT Type II. A review of HIT is presented, examining the important clinical symptoms and diagnostic indicators. The treatment of HIT is then discussed, with an emphasis on current therapies. An extensive literature review has been performed to present a comprehensive review of the causes, pathophysiology and treatment of HIT. *Correspondence to: Somendra Rao, MD Senior Resident, Department of Cardiology Indira Gandhi Medical College, Shimla, India, E-mail: sureshdev. rao@gmail.com Received: March 07, 2019; Accepted: March 26, 2019; Published: March 28, 2019 Introduction There are two types of HIT described. Type I is a non-immune, mediated, asymptomatic, transient drop in platelet count that occurs in some heparin treated patients. It is typically characterized by a lesser fall in platelet count within the first two days after heparin initiation and often returns to normal with continued heparin administration [1,2]. Type II (HIT-II) is an immune-mediated disorder characterized by the formation of antibodies against heparin-platelet factor 4 complexes. Since The frequency of HIT varies from 0.5% to 5%, depending on the patient population studied [3]. A meta-analysis noted an incidence of 2.6 percent [4]. It has recently been proposed that the term “HIT type I” be changed to “non‐immune heparin associated thrombocytopenia” and that the term “HIT type II” be changed to “HIT” to avoid confusion between the two syndromes","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73915183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harlequin-like syndrome after migrated interscalene catheter bolus injection 移位斜角肌间导管丸注后的丑角样综合征

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/CCSR.1000116

Ching-Rong Cheng, Navreet Sandhu

引用次数: 0

A case of recurrent ventriculitis associated with Colistin-Resistant Klebsiella pneumoniae in patient with ventriculoperitoneal shunt treated with intrathecal amikacin 经鞘内阿米卡星治疗脑室-腹膜分流患者并发耐粘菌素肺炎克雷伯菌复发脑室炎1例

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000132

A. Kaya, I. Balkan, S. Kaya, B. Altun, M. Yemisen, B. Mete, N. Saltoğlu, Y. Tunalı, G. Aygün, R. Ozturk

{"title":"A case of recurrent ventriculitis associated with Colistin-Resistant Klebsiella pneumoniae in patient with ventriculoperitoneal shunt treated with intrathecal amikacin","authors":"A. Kaya, I. Balkan, S. Kaya, B. Altun, M. Yemisen, B. Mete, N. Saltoğlu, Y. Tunalı, G. Aygün, R. Ozturk","doi":"10.15761/ccsr.1000132","DOIUrl":"https://doi.org/10.15761/ccsr.1000132","url":null,"abstract":"Carbapenem-resistant Klebsiella pneumoniae (CR-KP) strains have been increasingly seen as agents in the nosocomial infections in recent years. Many drugs, especially colistin are mostly used in the treatment of these pathogens [1]. As a natural result, we encountered colistinresistant strains in the hospital outbreak and infections. This challenge provide very limited treatment options for us and it shows that not only carbapenem but also colistin need to be used appropriately because of possibility of resistance [2]. Antibiotic resistance is seen due to unnecessarily and inappropriately using and not implementing hospital infection control procedures. Herein, we presented a patient who was administered intravenous (IV) + intrathecal colistin therapy due to recurrent ventriculitis associated with ventriculoperitoneal (VP) shunt. But the condition of the patient worsened under this treatment and then colistin-resistant Klebsiella pneumoniae (CoR-KP) was isolated from cerebrospinal fluid (CSF) culture. Finally, she could be successfully treated with intravenous and intrathecal amikacin use.","PeriodicalId":10345,"journal":{"name":"Clinical Case Studies and Reports","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89215485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Overlooked chronic constipation in adolescent: Hirschsprung Disease 被忽视的青少年慢性便秘:巨结肠病

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000115

Semire Serin Ezer

引用次数: 0

Donor selection in pre-sensitized patients for renal transplant 肾移植预致敏患者的供体选择

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/CCSR.1000118

S. Kankonkar

引用次数: 0

Eleven years of Maraviroc experience and limited side effects in a HIV-1 experienced patient. Long term antiretroviral observation 一名HIV-1患者11年的马拉韦洛克治疗经验和有限的副作用。长期抗逆转录病毒观察

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/CCSR.1000117

L. Brescini, L. Weimer, O. Cirioni, G. Morroni, A. Giacometti

引用次数: 0

A rare case of bilateral aldosterone producing adrenal masses with concurrent bilateral renal cell carcinoma and multiple benign neoplasia 一例罕见的双侧醛固酮肾上腺肿物并发双侧肾细胞癌及多发性良性肿瘤

Clinical Case Studies and Reports Pub Date : 2019-01-01 DOI: 10.15761/ccsr.1000135

S. Rabizadeh, F. Salahshour, F. Ahmadi, A. Esteghamati, A. Rajab, M. Nakhjavani

引用次数: 0

Rhabdomyolysis and acute renal failure after intense physical activity 剧烈运动后横纹肌溶解和急性肾功能衰竭

Clinical Case Studies and Reports Pub Date : 1900-01-01 DOI: 10.15761/ccsr.1000133

S. Nikpour, N. Zamani, F. Fahim, M. Farnia

引用次数: 0