Circulation Reports最新文献_第4页

Association Between Telomere G-Tail Length and Coronary Artery Disease or Statin Treatment in Patients With Cardiovascular Risks　- A Cross-Sectional Study. 端粒g尾长度与冠心病或心血管危险患者他汀类药物治疗之间的关系——一项横断面研究

Circulation Reports Pub Date : 2023-08-10 DOI: 10.1253/circrep.CR-23-0038

Daisuke Nose, Yuhei Shiga, Ryou-U Takahashi, Yuki Yamamoto, Yasunori Suematsu, Takashi Kuwano, Makoto Sugihara, Miyuki Kanda, Hidetoshi Tahara, Shin-Ichiro Miura

{"title":"Association Between Telomere G-Tail Length and Coronary Artery Disease or Statin Treatment in Patients With Cardiovascular Risks　- A Cross-Sectional Study.","authors":"Daisuke Nose, Yuhei Shiga, Ryou-U Takahashi, Yuki Yamamoto, Yasunori Suematsu, Takashi Kuwano, Makoto Sugihara, Miyuki Kanda, Hidetoshi Tahara, Shin-Ichiro Miura","doi":"10.1253/circrep.CR-23-0038","DOIUrl":"https://doi.org/10.1253/circrep.CR-23-0038","url":null,"abstract":"Background: The utility of telomere G-tail length to predict coronary artery disease (CAD) remains controversial. CAD results from coronary artery narrowing due to cholesterol and lipid accumulation, augmented by inflammatory cells and other factors. This study explored the significance of telomere G-tail length in suspected CAD patients. Methods and Results: In all, 95 patients with suspected CAD or ≥1 cardiac risk factor underwent coronary computed tomography angiography (CCTA). We measured leukocyte telomere length and G-tail length using a hybrid protection method, and diagnosed the presence of CAD using CCTA. Associations between G-tail length and the presence of CAD, the number of stenosed coronary arteries, and brachial-ankle pulse wave velocity (baPWV) were analyzed. No significant difference was observed in G-tail length when comparing groups with or without CAD or statin treatment. However, in the non-statin group, G-tail length was significantly shorter in patients with 3-vessel disease compared with 1-vessel disease. Dividing the group using a baPWV of 1,300 cm/s, telomere G-tail length was significantly shorter in the high-risk (baPWV ≥1,300 cm/s) group. Conclusions: The clinical utility of telomere G-tail length as a CAD risk indicator seems limited. There was a trend for longer telomere G-tail length in the statin-treated group. Moreover, telomere G-tail length was reduced in patients at high-risk of cardiovascular events, aligning with the trend of a shortening in telomere G-tail length with CAD severity.","PeriodicalId":10276,"journal":{"name":"Circulation Reports","volume":"5 8","pages":"338-347"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/93/circrep-5-338.PMC10411992.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between Results of Pathological Evaluation of Endomyocardial Biopsy and Echocardiographic Indices in Patients With Non-Ischemic Cardiomyopathy. 非缺血性心肌病患者心内膜活检病理评价结果与超声心动图指标的关系。

Circulation Reports Pub Date : 2023-08-10 DOI: 10.1253/circrep.CR-23-0062

Eiji Toyosaki, Yasuhide Mochizuki, Hiroki Den, Saaya Ichikawa, Haruka Miyazaki, Saori Chino, Rumi Hachiya, Hiroto Fukuoka, Akatsuki Kokaze, Takaaki Matsuyama, Toshiro Shinke

{"title":"Relationship Between Results of Pathological Evaluation of Endomyocardial Biopsy and Echocardiographic Indices in Patients With Non-Ischemic Cardiomyopathy.","authors":"Eiji Toyosaki, Yasuhide Mochizuki, Hiroki Den, Saaya Ichikawa, Haruka Miyazaki, Saori Chino, Rumi Hachiya, Hiroto Fukuoka, Akatsuki Kokaze, Takaaki Matsuyama, Toshiro Shinke","doi":"10.1253/circrep.CR-23-0062","DOIUrl":"https://doi.org/10.1253/circrep.CR-23-0062","url":null,"abstract":"Background: Endomyocardial biopsy (EMB) is a useful modality in diagnosing the origin of cardiomyopathy and the condition of the impaired myocardium. However, the usefulness of obtaining an EMB from the right and left ventricles (RV and LV, respectively), and its associations with echocardiographic parameters, have not been explored. Methods and Results: Ninety-five consecutive patients with non-ischemic cardiomyopathy excluding myocarditis who underwent EMB between July 2017 and May 2019 were studied. Seventy-nine RV and 93 LV biopsy specimens were pathologically analyzed. The relationships among echocardiographic data before EMB and pathologically measured cardiomyocyte diameter (CMD) and interstitial fibrosis (IF) were evaluated. CMD in both LV and RV specimens correlated with echocardiographic LV morphology, but only CMD in the LV was significantly correlated with cardiac function evaluation, including LV ejection fraction, E' and E/E'. In contrast, there were no significant correlations between IF in either the LV or RV and any echocardiographic parameters measured. Furthermore, CMD of both ventricles was significantly correlated with B-type natriuretic peptide (BNP) concentration at EMB, whereas IF of the LV was barely related and IF of the RV was not significantly correlated with BNP concentrations. Conclusions: Pathologically evaluated CMD of EMB specimens of the LV may be more related to functional parameters for heart failure status and LV geometry on echocardiographic examination, than IF.","PeriodicalId":10276,"journal":{"name":"Circulation Reports","volume":"5 8","pages":"331-337"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/d0/circrep-5-331.PMC10411993.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Affecting Recovery of 6-Minute Walk Distance After Coronary Artery Bypass Grafting. 影响冠状动脉搭桥术术后6分钟步行距离恢复的因素

Circulation Reports Pub Date : 2023-08-10 DOI: 10.1253/circrep.CR-23-0060

Naoya Araki, Takafumi Hirota, Hideaki Hidaka, Tatsuya Horibe, Ryosuke Numaguchi, Jun Takaki, Kosaku Nishigawa, Takashi Yoshinaga, Toshihiro Fukui

{"title":"Factors Affecting Recovery of 6-Minute Walk Distance After Coronary Artery Bypass Grafting.","authors":"Naoya Araki, Takafumi Hirota, Hideaki Hidaka, Tatsuya Horibe, Ryosuke Numaguchi, Jun Takaki, Kosaku Nishigawa, Takashi Yoshinaga, Toshihiro Fukui","doi":"10.1253/circrep.CR-23-0060","DOIUrl":"https://doi.org/10.1253/circrep.CR-23-0060","url":null,"abstract":"Background: This single-center retrospective analysis investigated the number of days required for postoperative 6-minute walk distance (6MWD) to recover to preoperative values after coronary artery bypass grafting (CABG) and the factors influencing this recovery. Methods and Results: The 6MWD was measured in 101 patients (median age 69 years; 18 women) before and every day after CABG. Univariate and multivariate analyses were performed to identify factors affecting 6MWD recovery to preoperative values after CABG. The median number of days required for recovery of 6MWD after CABG was 9 (interquartile range 7-11 days). Patients were divided into 2 groups based on the median number of days required for recovery of 6MWD; there were 60 patients in the early recovery group (<9 days) and 41 in the \"non-early\" recovery group (38 who recovered after the median 9 days, and 3 who did not recover during hospitalization). Using univariate logistic regression analysis, diabetes (P=0.01), stroke (P=0.26), left ventricular ejection fraction (P=0.27), and grip strength (P=0.13) were selected for multivariate analysis. Multivariate logistic regression analysis revealed that diabetes (odds ratio 2.955; 95% confidence interval 1.208-7.229; P=0.02) was the only independent predictor of 6MWD recovery. Conclusions: Diabetes was the single factor influencing the recovery of postoperative 6MWD in patients undergoing CABG.","PeriodicalId":10276,"journal":{"name":"Circulation Reports","volume":"5 8","pages":"317-322"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/27/c4/circrep-5-317.PMC10411994.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

High-Output Heart Failure Caused by Abdominal Aortic Aneurysm-Inferior Vena Cava Fistula Due to Blunt Trauma. 钝性外伤所致腹主动脉瘤-下腔静脉瘘致高输出量心力衰竭。

Circulation Reports Pub Date : 2023-08-10 DOI: 10.1253/circrep.CR-23-0046

Eri Morita, Kenji Harada, Shunsuke Saito, Kazuomi Kario

引用次数: 0

Ubiquitin, p62, and Microtubule-Associated Protein 1 Light Chain 3 in Cardiomyopathy. 泛素、p62和微管相关蛋白1轻链3在心肌病中的作用。

Circulation Reports Pub Date : 2023-08-10 DOI: 10.1253/circrep.CR-23-0058

Ryo Eto, Hiroaki Kawano, Mutsumi Matsuyama-Matsuu, Katsuya Matsuda, Nozomi Ueki, Masahiro Nakashima, Shinji Okano, Mitsuaki Ishijima, Miho Kawakatsu, Jumpei Watanabe, Tsuyoshi Yoshimuta, Satoshi Ikeda, Koji Maemura

{"title":"Ubiquitin, p62, and Microtubule-Associated Protein 1 Light Chain 3 in Cardiomyopathy.","authors":"Ryo Eto, Hiroaki Kawano, Mutsumi Matsuyama-Matsuu, Katsuya Matsuda, Nozomi Ueki, Masahiro Nakashima, Shinji Okano, Mitsuaki Ishijima, Miho Kawakatsu, Jumpei Watanabe, Tsuyoshi Yoshimuta, Satoshi Ikeda, Koji Maemura","doi":"10.1253/circrep.CR-23-0058","DOIUrl":"https://doi.org/10.1253/circrep.CR-23-0058","url":null,"abstract":"Background: The accumulation of ubiquitinated proteins has been detected in diseased hearts and has been associated with the expression of p62 and microtubule-associated protein 1 light chain 3 (LC3), which are related to autophagy. We evaluated differences in ubiquitin accumulation and p62 and LC3 expression in cardiomyopathy using endomyocardial biopsies. Methods and Results: We studied 24 patients (aged 24-70 years; mean age 55 years) diagnosed with dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), or non-cardiomyopathy (NCM) who underwent endomyocardial biopsy. Biopsied samples were evaluated by microscopy for ubiquitin accumulation and expression of p62 and LC3. Ubiquitin accumulation and p62 and LC3 expression were observed in all patients. Ubiquitin accumulation was higher in DCM than in HCM or NCM; p62 expression was higher in DCM than in HCM. There were no significant differences in LC3 expression among the groups. Ubiquitin accumulation was significantly related to serum N-terminal pro B-type natriuretic peptide concentration and the expression of p62, but not LC3. Conclusions: Ubiquitin accumulation was more prominent in DCM than in HCM and NCM, which may be due to a relative shortage of clearance, including autophagy, compared with production.","PeriodicalId":10276,"journal":{"name":"Circulation Reports","volume":"5 8","pages":"323-330"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fb/24/circrep-5-323.PMC10411995.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9969710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hybrid Treatment for a Distal Left Main Coronary Artery Aneurysm　- Coronary Artery Bypass Grafting and Surgical Ligation Followed by Intraoperative Covered Stent Implantation. 左主干远端冠状动脉动脉瘤的混合治疗-冠状动脉搭桥术结扎后术中覆膜支架植入术。

Circulation Reports Pub Date : 2023-07-10 DOI: 10.1253/circrep.CR-23-0018

Hiroyuki Yamamoto, Takahiro Sawada, Hirohisa Murakami, Tomofumi Takaya

引用次数: 0

Pneumopericardium After the Removal of a Pericardiocentesis Drain. 心包穿刺引流管取出后的心包气肿。

Circulation Reports Pub Date : 2023-07-10 DOI: 10.1253/circrep.CR-23-0023

Junya Tanabe, Hiraku Murakami, Yasuhiro Akazawa, Daisuke Nakamura, Fusako Sera, Takahumi Oka, Kentaro Fukushima, Tomohito Ohtani, Naoki Hosen, Yasushi Sakata

引用次数: 0

Distal Balloon Inflation Technique　- A Bailout Method of Difficulty in Crossing Balloon-Expandable Valve Delivery System Due to Unfavorable Guidewire Position During Transcatheter Aortic Valve Replacement. 远端球囊充气技术——经导管主动脉瓣置换术中由于导丝位置不利导致球囊-可膨胀瓣膜传送系统难以通过的救助方法。

Circulation Reports Pub Date : 2023-07-10 DOI: 10.1253/circrep.CR-23-0013

Akiko Masumoto, Yoshiro Tsukiyama, Nobuyuki Takahashi, Hiroyuki Yamamoto, Tomofumi Takaya

引用次数: 0

Prevalence and Treatment of Arrhythmias in Patients With Transthyretin and Light-Chain Cardiac Amyloidosis. Transthyretin和轻链心脏淀粉样变性患者心律失常的患病率和治疗方法。

Circulation Reports Pub Date : 2023-06-23 eCollection Date: 2023-07-10 DOI: 10.1253/circrep.CR-23-0022

Masakazu Miyamoto, Kazufumi Nakamura, Koji Nakagawa, Nobuhiro Nishii, Satoshi Kawada, Akira Ueoka, Saori Asada, Atsuyuki Watanabe, Hiroshi Morita, Hiroshi Ito

{"title":"Prevalence and Treatment of Arrhythmias in Patients With Transthyretin and Light-Chain Cardiac Amyloidosis.","authors":"Masakazu Miyamoto, Kazufumi Nakamura, Koji Nakagawa, Nobuhiro Nishii, Satoshi Kawada, Akira Ueoka, Saori Asada, Atsuyuki Watanabe, Hiroshi Morita, Hiroshi Ito","doi":"10.1253/circrep.CR-23-0022","DOIUrl":"10.1253/circrep.CR-23-0022","url":null,"abstract":"Background: Various types of arrhythmia are observed in patients with cardiac amyloidosis, but the prevalence of arrhythmia has not been fully investigated. This study investigated the prevalence and treatment of arrhythmias in patients with cardiac amyloidosis before the introduction of new agents for amyloidosis, such as tafamidis. Methods and Results: Of 53 patients who were histologically diagnosed with cardiac amyloidosis at 10 centers in western Japan between 2009 and 2021, 43 who were diagnosed on the basis of immunohistochemical staining were evaluated in this study. Of these 43 patients, 13 had immunoglobulin light-chain (AL) amyloidosis and 30 had transthyretin (ATTR) amyloidosis; further, 27 had atrial tachyarrhythmia, 13 had ventricular tachyarrhythmia, and 17 had bradyarrhythmia. Atrial fibrillation (AF) was the most common arrhythmia in patients with cardiac amyloidosis (n=24; 55.8%), especially among those with ATTR amyloidosis (70.0% of ATTR vs. 23.1% of AL). Eleven (25.6%) patients were treated with a cardiac implantable device. All 3 patients with pacemakers were alive at the last follow-up (median 76.7 months; interquartile range [IQR] 4.8-146.4 months). Of the 8 patients who underwent AF ablation, there was no recurrence in 6 (75%) after a median of 39.3 months (IQR 19.8-59.3 months). Conclusions: The prevalence of various arrhythmias was high in patients with cardiac amyloidosis. AF occurred most frequently in patients with cardiac amyloidosis, especially among patients with ATTR.","PeriodicalId":10276,"journal":{"name":"Circulation Reports","volume":"5 7","pages":"298-305"},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/6d/circrep-5-298.PMC10329899.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9813386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Radar Chart-Based Information Sharing in a Multidisciplinary Team on In-Hospital Outcomes and Prognosis in Older Patients With Heart Failure. 多学科团队基于雷达病历的信息共享对老年心力衰竭患者院内预后的影响

Circulation Reports Pub Date : 2023-06-20 eCollection Date: 2023-07-10 DOI: 10.1253/circrep.CR-23-0049

Satoshi Katano, Toshiyuki Yano, Ryo Numazawa, Ryohei Nagaoka, Kotaro Yamano, Yusuke Fujisawa, Suguru Honma, Ayako Watanabe, Katsuhiko Ohori, Hidemichi Kouzu, Takefumi Fujito, Tomoyuki Ishigo, Hayato Kunihara, Hiroya Fujisaki, Masaki Katayose, Akiyoshi Hashimoto, Masato Furuhashi

{"title":"Impact of Radar Chart-Based Information Sharing in a Multidisciplinary Team on In-Hospital Outcomes and Prognosis in Older Patients With Heart Failure.","authors":"Satoshi Katano, Toshiyuki Yano, Ryo Numazawa, Ryohei Nagaoka, Kotaro Yamano, Yusuke Fujisawa, Suguru Honma, Ayako Watanabe, Katsuhiko Ohori, Hidemichi Kouzu, Takefumi Fujito, Tomoyuki Ishigo, Hayato Kunihara, Hiroya Fujisaki, Masaki Katayose, Akiyoshi Hashimoto, Masato Furuhashi","doi":"10.1253/circrep.CR-23-0049","DOIUrl":"10.1253/circrep.CR-23-0049","url":null,"abstract":"Background: A multidisciplinary team (MDT) approach is crucial for managing older patients with heart failure (HF). We investigated the impact on clinical outcomes of implementation of a conference sheet (CS) with an 8-component radar chart for visualizing and sharing patient information. Methods and Results: We enrolled 395 older inpatients with HF (median age 79 years [interquartile range 72-85 years]; 47% women) and divided them into 2 groups according to CS implementation: a non-CS group (before CS implementation; n=145) and a CS group (after CS implementation; n=250). The clinical characteristics of patients in the CS group were assessed using 8 scales (physical function, functional status, comorbidities, nutritional status, medication adherence, cognitive function, HF knowledge level, and home care level). In-hospital outcomes (Short Physical Performance Battery, Barthel Index score, length of hospital stay, and hospital transfer rate) were significantly better in the CS than non-CS group. During the follow-up period, 112 patients experienced composite events (all-cause death or admission for HF). Inverse probabilities of treatment-weighted Cox proportional hazard analyses demonstrated a 39% reduction in risk of composite events in the CS group (adjusted hazard ratio 0.65; 95% confidence interval 0.43-0.97). Conclusions: Radar chart-based information sharing among MDT members is associated with superior in-hospital clinical outcomes and a favorable prognosis.","PeriodicalId":10276,"journal":{"name":"Circulation Reports","volume":"5 7","pages":"271-281"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/26/circrep-5-271.PMC10329901.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0