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Clinical and Molecular Hepatology最新文献

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Comparison of the therapeutic effects of transarterial radioembolization and tyrosine kinase inhibitor in hepatocellular carcinoma with portal vein thrombosis. 经动脉放射栓塞术和酪氨酸激酶抑制剂对伴有门静脉血栓形成的肝癌的治疗效果比较。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-10-07 DOI: 10.3350/cmh.2024.0832
Hang Li, Hua Lu, Xi-Ping Shen, Xiao-Song Li
{"title":"Comparison of the therapeutic effects of transarterial radioembolization and tyrosine kinase inhibitor in hepatocellular carcinoma with portal vein thrombosis.","authors":"Hang Li, Hua Lu, Xi-Ping Shen, Xiao-Song Li","doi":"10.3350/cmh.2024.0832","DOIUrl":"10.3350/cmh.2024.0832","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e3-e4"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of risk scores for prognosis prediction among patients with early-stage hepatocellular carcinoma. 为早期肝细胞癌患者的预后预测制定风险评分。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-10-11 DOI: 10.3350/cmh.2024.0794
Xiping Shen, Ji Wu
{"title":"Development of risk scores for prognosis prediction among patients with early-stage hepatocellular carcinoma.","authors":"Xiping Shen, Ji Wu","doi":"10.3350/cmh.2024.0794","DOIUrl":"10.3350/cmh.2024.0794","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e17-e18"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioactive metabolites: A clue to the link between MASLD and CKD? 生物活性代谢物：MASLD 与慢性肾脏病之间联系的线索？
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-10-21 DOI: 10.3350/cmh.2024.0782
Wen-Ying Chen, Jia-Hui Zhang, Li-Li Chen, Christopher D Byrne, Giovanni Targher, Liang Luo, Yan Ni, Ming-Hua Zheng, Dan-Qin Sun
{"title":"Bioactive metabolites: A clue to the link between MASLD and CKD?","authors":"Wen-Ying Chen, Jia-Hui Zhang, Li-Li Chen, Christopher D Byrne, Giovanni Targher, Liang Luo, Yan Ni, Ming-Hua Zheng, Dan-Qin Sun","doi":"10.3350/cmh.2024.0782","DOIUrl":"10.3350/cmh.2024.0782","url":null,"abstract":"<p><p>Metabolites produced as intermediaries or end-products of microbial metabolism provide crucial signals for health and diseases, such as metabolic dysfunction-associated steatotic liver disease (MASLD). These metabolites include products of the bacterial metabolism of dietary substrates, modification of host molecules (such as bile acids [BAs], trimethylamine-N-oxide, and short-chain fatty acids), or products directly derived from bacteria. Recent studies have provided new insights into the association between MASLD and the risk of developing chronic kidney disease (CKD). Furthermore, alterations in microbiota composition and metabolite profiles, notably altered BAs, have been described in studies investigating the association between MASLD and the risk of CKD. This narrative review discusses alterations of specific classes of metabolites, BAs, fructose, vitamin D, and microbiota composition that may be implicated in the link between MASLD and CKD.</p>","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"56-73"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correspondence to editorial on "Long-term gastrointestinal and hepatobiliary outcomes of COVID-19: a multinational population-based cohort study from South Korea, Japan, and the UK". 关于 "了解后 COVID-19 条件对消化系统疾病的影响 "社论的通信。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-10-29 DOI: 10.3350/cmh.2024.0935
Kwanjoo Lee, Jaeyu Park, Jinseok Lee, Hayeon Lee, Yeonjung Ha, Dong Keon Yon
{"title":"Correspondence to editorial on \"Long-term gastrointestinal and hepatobiliary outcomes of COVID-19: a multinational population-based cohort study from South Korea, Japan, and the UK\".","authors":"Kwanjoo Lee, Jaeyu Park, Jinseok Lee, Hayeon Lee, Yeonjung Ha, Dong Keon Yon","doi":"10.3350/cmh.2024.0935","DOIUrl":"10.3350/cmh.2024.0935","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e87-e89"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correspondence to editorial 2 on "Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: insights from the IMbrave150 trial". 关于 "使用免疫检查点抑制剂治疗肝细胞癌的个性化方法 "信函的通信。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-10-07 DOI: 10.3350/cmh.2024.0830
Sun Young Yim, Sung Hwan Lee, Ji Hoon Kim, Sunyoung S Lee, Ahmed O Kaseb, Ju-Seog Lee
{"title":"Correspondence to editorial 2 on \"Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: insights from the IMbrave150 trial\".","authors":"Sun Young Yim, Sung Hwan Lee, Ji Hoon Kim, Sunyoung S Lee, Ahmed O Kaseb, Ju-Seog Lee","doi":"10.3350/cmh.2024.0830","DOIUrl":"10.3350/cmh.2024.0830","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e84-e86"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steatotic liver disease in chronic hepatitis C related hepatocellular carcinoma: Inflictor or bystander?: Correspondence to editorial on "Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan". 与慢性丙型肝炎相关的肝细胞癌中的脂肪肝：施害者还是旁观者？
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-08-19 DOI: 10.3350/cmh.2024.0638
Chung-Feng Huang, Ming-Lun Yeh, Chia-Yen Dai, Jee-Fu Huang, Wan-Long Chuang, Ming-Lung Yu
{"title":"Steatotic liver disease in chronic hepatitis C related hepatocellular carcinoma: Inflictor or bystander?: Correspondence to editorial on \"Dynamic change of metabolic dysfunction-associated steatotic liver disease in chronic hepatitis C patients after viral eradication: A nationwide registry study in Taiwan\".","authors":"Chung-Feng Huang, Ming-Lun Yeh, Chia-Yen Dai, Jee-Fu Huang, Wan-Long Chuang, Ming-Lung Yu","doi":"10.3350/cmh.2024.0638","DOIUrl":"10.3350/cmh.2024.0638","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e64-e66"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142003742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A complement to epigenetics in metabolic dysfunction-associated steatotic liver disease: Editorial on "DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease". MASLD 中表观遗传学的补充。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-08-27 DOI: 10.3350/cmh.2024.0704
Johanna K DiStefano, Glenn S Gerhard
{"title":"A complement to epigenetics in metabolic dysfunction-associated steatotic liver disease: Editorial on \"DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease\".","authors":"Johanna K DiStefano, Glenn S Gerhard","doi":"10.3350/cmh.2024.0704","DOIUrl":"10.3350/cmh.2024.0704","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"297-300"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TM6SF2 and PNPLA3: A potential dynamic duo?: Editorial on "TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD". TM6SF2 和 PNPLA3：潜在的动态二重奏？
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-08-27 DOI: 10.3350/cmh.2024.0703
Andrea Caddeo, Rosellina M Mancina
{"title":"TM6SF2 and PNPLA3: A potential dynamic duo?: Editorial on \"TM6SF2 E167K variant decreases PNPLA3-mediated PUFA transfer to promote hepatic steatosis and injury in MASLD\".","authors":"Andrea Caddeo, Rosellina M Mancina","doi":"10.3350/cmh.2024.0703","DOIUrl":"10.3350/cmh.2024.0703","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"293-296"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-specific associations of metabolic dysfunction-associated steatotic liver disease with cardiovascular outcomes. 代谢功能障碍相关脂肪性肝病与心血管后果的性别特异性关联。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-09-20 DOI: 10.3350/cmh.2024.0719
Meng-Yuan Miao, Jie-Qiong Lyu, Wei Jiang, Zhong-Yue Liu, Guo-Chong Chen
{"title":"Sex-specific associations of metabolic dysfunction-associated steatotic liver disease with cardiovascular outcomes.","authors":"Meng-Yuan Miao, Jie-Qiong Lyu, Wei Jiang, Zhong-Yue Liu, Guo-Chong Chen","doi":"10.3350/cmh.2024.0719","DOIUrl":"10.3350/cmh.2024.0719","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e35-e38"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correspondence to letter to the editor on "Bariatric intervention improves metabolic dysfunction-associated steatohepatitis in patients with obesity: A systematic review and meta-analysis". 回复关于 "减肥干预可改善肥胖症患者代谢功能障碍相关性脂肪性肝炎：系统回顾和荟萃分析 "的回信。
IF 14 1区 医学
Clinical and Molecular Hepatology Pub Date : 2025-01-01 Epub Date: 2024-09-24 DOI: 10.3350/cmh.2024.0818
Yuri Cho, Dae Won Jun
{"title":"Correspondence to letter to the editor on \"Bariatric intervention improves metabolic dysfunction-associated steatohepatitis in patients with obesity: A systematic review and meta-analysis\".","authors":"Yuri Cho, Dae Won Jun","doi":"10.3350/cmh.2024.0818","DOIUrl":"10.3350/cmh.2024.0818","url":null,"abstract":"","PeriodicalId":10275,"journal":{"name":"Clinical and Molecular Hepatology","volume":" ","pages":"e103-e104"},"PeriodicalIF":14.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142307243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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