Clinical and Experimental Health Sciences最新文献

{"title":"Fear of Getting Pregnant Scale Development Study","authors":"Nursel Alp Dal, K. Beydağ","doi":"10.33808/clinexphealthsci.1166793","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1166793","url":null,"abstract":"Purpose: This study was carried out in order to develop a measurement tool that determines the factors that may be effective in women's fear of getting pregnant and to bring it into the literature. \u0000Methods: The sample of the study, which was carried out in methodological and analytical type, consisted of 240 sexually active women who applied to the obstetrics clinic of a hospital in the Anatolian side of Istanbul between February 1 and June 1, 2021. The study data were obtained with the \"Personal Information Form\" and the \"Fear of Getting Pregnant Scale\" created by the researchers. The draft scale, which consisted of 22 items when it was first developed, took its final form with 18 items as a result of the necessary validity and reliability studies. The scale consisted of three sub-dimensions: “physical reasons” (5 items), “psychological reasons” (6 items), and “social reasons” (7 items). Explanatory factor analysis, confirmatory factor analysis, Barlett test, Cronbach alpha test, Shapiro-Wilk test were used in the development of the scale. After evaluating the content validity of the scale, test-retest reliability, internal consistency and construct validity were examined. \u0000Results: In the validity and reliability study of the Fear of Getting Pregnant Scale, the Content Validity Index (CVI) was found to be “0.837”. The total cronbach alpha value of the scale was determined as 0.951, and the cronbach alpha value for the \"physical reasons\" sub-dimension was 0.910, the cronbach alpha value for the \"psychological reasons\" sub-dimension was 0.898, and the cronbach alpha value for the \"social reasons\" sub-dimension was 0.904. \u0000Conclusion: In line with these data, it was determined that the “Fear of Getting Pregnant Scale” is a valid and reliable scale.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49033109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of The Musical Snow Globe Used in Infancy Vaccination Applications on The Level of Pain: A Randomized Controlled Study","authors":"Betül AKKOÇ, Tülay AYYILDIZ","doi":"10.33808/clinexphealthsci.1191934","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1191934","url":null,"abstract":"Objective: This randomized controlled trial was conducted to investigate the effect of a musical snow globe on reducing pain associated with vaccine administration in infants 2-6 months of age. 
 Method: The sample of the study consisted of 78 infants (experimental group (EG):39, control group (CG): 39 babies) who applied to the family health center between the specified dates and met the case selection criteria. The Face, Legs, Activity, Crying, and Comfort (FLACC) Scale was used to assess infants' pain before, during, and after immunization. Heart rate and oxygen saturation in the infants' blood were measured as part of the study. During vaccine administration, infants in the experimental group were shown a snow globe with music, while infants in control group were vaccinated with a routine health application. 
 Results: There was no statistically significant difference (p>.05) between the SpO2 values before the interventions (EG: 99.46 CG: 99.56) and the SpO2 values after the interventions (EG: 96.30 CG: 96.05) of the babies in the experimental and control groups; In heart rates, there was no statistically significant difference (p>.05) between befoere the interventions (EG:127.31 CG:127.71) and after the interventions (EG:140.10 CG:147.66) values. However, a significant difference was found between SpO2 (EG: 95.20 CG: 93.23) and heart rate values (EG: 145.76 CG: 157.33) during the intervention (p.05); however, the FLACC scores of the infants in the experimental group were lower than the infants in the control group at the time of the intervention (EG: 3.89 CG: 6.92) (p","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135081096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The opinions of postgraduate nursing students about evidence-based practice: A qualitative study","authors":"S. Yurt, N. Kolac, Esra Sen","doi":"10.33808/clinexphealthsci.932298","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.932298","url":null,"abstract":"Objective: This study was conducted for the purpose of exploring the opinions and experiences of postgraduate nursing students regarding evidence-based practice and its use in the clinical setting in Turkey. \u0000Methods: A qualitative study design was employed. Data in this research study were collected through Semi-structured questions were asked face-to-face in focus group discussions. \u0000Results: The findings of the study set forth the individual and organizational barriers that faced postgraduate nursing students in their efforts \u0000to implement evidence-based practices. The main themes of the study were highlighted as: perceptions regarding evidence-based practice, the impact on the group cared for, challenges faced in the implementation, institutional support in applying practices. Subthemes were data verification, useful and reliable application, difficulties in communicating with colleagues, traditional views, troubles with team collaboration, the indifference of young colleagues, insufficient resources, and the need for a mentor in the workplace. \u0000Conclusion: The students in their undergraduate programs, and elective courses on EBP should be added to the curriculum. In order to eliminate organizational barriers, institutions should establish EBP committee and mentoring system.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46811166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Reboxetine Treatment on BDNF, Synaptophysin, and PSD-95 Levels in the Spinal Dorsal Horn of Rats with Diabetic Neuropathy","authors":"Nazlı Turan Yücel, Umut İrfan Üçel, Ümide Demir Özkay, E. Ulupınar, Ö. Can","doi":"10.33808/clinexphealthsci.1222028","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1222028","url":null,"abstract":"Objective: It is known that neuropathic pain is accompanied by alterations in the levels of neurotrophic factors and synaptic proteins in the microenvironment of the spinal dorsal horn. Such changes contribute to hyperalgesia and allodynia processes; thus, analgesic drugs can exert their pharmacological effects by affecting the expressions, levels, or functions of these endogenous substances. In this study, based on the knowledge that reboxetine (a selective noradrenaline reuptake inhibitor) has the potential for antihyperalgesic efficacy in diabetic neuropathy, we aimed to examine the probable effects of this drug on diabetes-induced changes in brain-derived neurotrophic factor (BDNF), synaptophysin (the pre-synaptic marker of synaptic integration), and postsynaptic density-95 (PSD-95) (the postsynaptic marker of synaptic integration) levels in the superficial laminae of the dorsal horn. \u0000Methods: Experimental diabetes was induced by a single-dose injection of streptozotocin (STZ) (50 mg/kg) in rats. After four week-long induction period of painful diabetic neuropathy, rats were treated orally with 8 mg/kg reboxetine for two weeks. Hyperalgesia responses were evaluated by using the Randall–Selitto and Hargreave's tests. Following the pain tests, immunohistochemical studies were performed. \u0000Results: Two weeks of reboxetine administration increased the reduced paw withdrawal thresholds and shortened the paw withdrawal latencies of diabetic rats in neuropathic pain tests, indicating the antihyperalgesic efficacy of this drug. Moreover, augmented BDNF and synaptophysin levels in diabetic rats reversed by reboxetine treatment. However, there was no alteration in the densities of PSD-95, in both STZ-diabetic and reboxetine-treated STZ-diabetic rats. \u0000Conclusion: The obtained results suggested that inhibition of central sensitization and modulation of spinal plasticity seem to be pharmacological mechanisms underlying reboxetine's antihyperalgesic effects on diabetic rats. However, further studies are still needed to clarify the exact mechanism of action.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45621408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Effect of Jointly Administering Synthetic Graft and Ankaferd Blood Stopper for Bone Recovery in Created Bone Deformities in Diabetic Rats","authors":"Abdulsamet Tanık, A. Dogru, M. Gül","doi":"10.33808/clinexphealthsci.1080508","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1080508","url":null,"abstract":"Objective: In the present paper, it was purposed to examine the late impacts of bone tissue recoveries in combination with synthetic grafts and Ankaferd Blood Stopper (ABS), which are effective in bone wound healing in diabetic rats. \u0000Methods: A total of 64 Wistar albino male rats with diabetes were studied. A bone deformity was generated in the calvarium of diabetic rats. These diabetic rats are divided into 4 different groups. Only saline was applied to the bone defect in group 1, Beta-tricalcium phosphate (β-TCP) graft was administered to Group 2, ABS solution to Group 3, (β-TCP+ABS) were administered to group 4. Eight rats from each group were sacrificed on the 28th day and another 8 rats on the 56th day. Immunohistochemical, histopathological, and Dual Energy X-ray Absorptiometry (DEXA) analyzes of the obtained samples were made. \u0000Results: In histopathological measurements, osteoblastic activity and bone regeneration were considerably higher in the group treated with group 2 and group 4 when compared to the control group on the 28th and 56th day (p˂ .05). Western blotting findings showed that the osteopontin (OP) and osteonectin (ON) expression at 28th day increased dramatically in the treated with group 4. DEXA analyzes revealed that BMC values in groups treated with group 2, group 3 and group 4 on 28th day were considerably higher than the control group (p˂ .05). \u0000Conclusion: We can believe and conclude that ABS in combination with a β-TCP bone graft will produce more successful outcomes on wound \u0000healing and formation of new bone in diabetic rats.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49414208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience, Thoughts, and Attitudes of Orthopaedic Surgeons about Chronic Postsurgical Pain after Arthroplasty","authors":"Selin Balta, Muhammet Zeki Gültekin","doi":"10.33808/clinexphealthsci.1078755","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1078755","url":null,"abstract":"Objective: Arthroplasty constitutes a major procedure commonly used in orthopaedic and traumatology surgery, and chronic pain develops in 7%–34% of patients after arthroplasty. This study aims to evaluate the experience, thoughts and attitudes of orthopaedic surgeons about chronic postsurgical pain after arthroplasty. \u0000Methods: The survey was sent to orthopaedic surgeons via the Google survey system. The questionnaire consisted of 17 questions in total; four were related to demographic information, two asked about the surgeons’ experience, three asked for their thoughts, and eight queried their attitudes. \u0000Results: The study evaluated 319 participants. All the orthopaedic surgeons reported that they routinely prescribe for postoperative pain control when discharging patients after arthroplasty. Of those surveyed, 69.7% have used multimodal analgesic therapy to treat chronic postsurgical \u0000pain after arthroplasty. Consultation rates were 5% and 20% for psychiatry and pain physician, respectively. A weak positive correlation was \u0000found between the rate of referring patients with chronic postsurgical pain after arthroplasty to pain physician and the beliefs of orthopaedic surgeons that pain physician can help patients with chronic postsurgical pain after arthroplasty who are unresponsive to pharmacological treatments (p = 0.008, r = 0.148). \u0000Conclusion: Orthopaedic surgeons employ pre-emptive approaches to chronic postsurgical pain after arthroplasty and engage in pharmacological management of chronic postsurgical pain after arthroplasty, but they need to advance further with multidisciplinary treatments and directions.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45763210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Staging and Grading of Periodontitis and Periimplantitis: A Retrospective Study","authors":"Hafize ÖZTÜRK ÖZENER","doi":"10.33808/clinexphealthsci.1224054","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1224054","url":null,"abstract":"Objective: The purpose of this retrospective study was to determine the relationship between peri-implantitis and stage/grade of periodontitis. \u0000Methods: Records of 171 periodontitis patients with 318 dental implants were screened. Classification of diagnosed patients with periodontitis were done by both stage (1, 2, 3 and 4) and grade (A, B and C). Peri-implant health status was evaluated as no peri-implantitis or with peri-implantitis. Marginal bone loss severity of implants diagnosed with peri-implantitis, prosthesis type (single, bridge), location of dental implants (maxilla, mandibula, anterior and posterior), smoking (yes/no) and diabetes history (yes/no) of the patients were also evaluated. Analysis was done at implant level. \u0000Results: A total of 203 (63.8%) dental implants were diagnosed with peri-implantitis. There were statistical differences in the stage and grade of periodontitis between implants diagnosed with no peri-implantitis and peri-implantitis (p","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49252470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Self-Rated Health for Adults in Türkiye","authors":"Duygu Ürek, Sevilay Karaman, İpek Bi̇lgi̇n, Özgür Uğurluoğlu, Oğuz Işık","doi":"10.33808/clinexphealthsci.923476","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.923476","url":null,"abstract":"Objective: Self-rated health as an important health outcome is affected by several factors. It is of great importance to investigate the determinants of self-rated health of individuals in order to obtain better results regarding public health. The purpose of this study was to determine the factors that affect the self-rated health of adults in Türkiye. \u0000Methods: Logistic regression analysis was performed to analyze data from the TurkStat’s 2014 Health Survey, with 19,129 people. The independent variables were related to socio-economic characteristics, health problems, lifestyle, and utilisation of healthcare services, while the dependent variable was self-rated health. \u0000Results: It was found that younger people, men, and people with higher educational and income levels rated their health status better. The health status of individuals with chronic diseases, mental disorders, sleeping problems and those who did not have a normal range body mass index also rated their health status as poor. However, the self-rated health of people who had no inpatient treatment in the last 12 months and those who took no prescription medicine in the last two weeks was good. \u0000Conclusion: This study provided the identification of the most advantaged and disadvantaged groups through determining the factors affecting the health status of adults in Türkiye. To improve the unfavourable condition of disadvantaged individuals, more specific interventions need to be designed and implemented.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43973644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability, Concurrent Validity, and Minimal Detectable Change of a Smartphone Application for Measuring Thoracic Kyphosis","authors":"Ertan Şahinoğlu, Gülbin Ergin, Serkan Bakırhan, B. Ünver","doi":"10.33808/clinexphealthsci.1038122","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1038122","url":null,"abstract":"Objective: To assess the intra- and inter-rater reliability and concurrent validity, and to estimate minimal detectable change of a smartphone application for measuring thoracic kyphosis angle. \u0000Methods: A total of 80 healthy university students were evaluated. Two raters measured the thoracic kyphosis angle using a digital inclinometer and the smartphone application. Intra- and inter-rater reliability were assessed using the intraclass correlation coefficient (ICC) with 95% confidence interval. The standard error of measurement (SEM) and the minimal detectable change at the 95% confidence level (MDC95) were also calculated. The concurrent validity between the digital inclinometer and the smartphone application was assessed by the linear regression analysis and Bland and Altman's 95% limits of agreement method. \u0000Results: The intra- and inter-rater reliability were excellent for the digital inclinometer and the smartphone application (ICC > 0.75). The SEM values for the digital inclinometer and the smartphone application were close together. The MDC95 values for the smartphone application were 5.11 and 6.30 degrees, and 9.02 degrees for intra- and inter-rater, respectively. The digital inclinometer and the smartphone application showed a positive correlation (R2 = 0.85). The Bland-Altman plot showed a good agreement between the instruments. \u0000Conclusion: The smartphone application used in this study is a cost-effective, practical, reliable, and valid instrument for measuring the thoracic kyphosis angle. More than 9 degrees in the value of the thoracic kyphosis angle measured by the smartphone application can be considered as a true change.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44038060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of in vitro Antioxidant, Antimicrobial and Cytotoxic Activities of Crude Ethanol Extract and Fractions of Achillea sintenisii Hub. Mor.","authors":"Nuraniye Eruygur, M. Atas, Mehmet Teki̇n, Ozge Cevi̇k","doi":"10.33808/clinexphealthsci.1058614","DOIUrl":"https://doi.org/10.33808/clinexphealthsci.1058614","url":null,"abstract":"Objective: The Achillea species have been used to treat various ailments due to its anti-inflammatory, hemostatic, spasmolytic and cholagogue effects in the Turkish traditional medicine. However, there is no biological activity studies on some Achillea species except for the well-knowns. This work aimed to determine the antioxidant, antimicrobial and cytotoxic activities of the crude ethanolic extracts and fractions of Achillea sintenisii using in vitro methods. \u0000Methods: The antioxidant activity was investigated by DPPH (1,1´-diphenyl- 2-picrylhydrazyl), ABTS (2,2´-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging, total phenol and total flavonoid content, and iron chelating methods. Antimicrobial activity evaluated by micro-plate dilution method against five test organisms. Cytotoxicity was determined by MTT method using MCF-7 breast cancer cell line and PC-3 prostate cancer cell line. Apoptosis was also measured by AO/EB staining. \u0000Results: The n-Hexane fractions showed the highest antimicrobial and cytotoxic activities, respectively. Administration of the extracts on the cancer cells showed a concentration dependent inhibition on cell proliferation. The anti-proliferation effect could be via apoptosis and associated with the cell death. \u0000Conclusion: The results showed that the extracts demonstrated antioxidant, antimicrobial, and cytotoxic activity, also supports the claims of traditional usage.","PeriodicalId":10192,"journal":{"name":"Clinical and Experimental Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42943674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}