Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih最新文献

{"title":"The Next-Level Precision Medicine in Cancer Management Using Artificial Intelligence.","authors":"Jie Tian","doi":"10.24920/004013","DOIUrl":"https://doi.org/10.24920/004013","url":null,"abstract":"","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"36 3","pages":"171-172"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39533232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological Diagnosis System for Gastritis Using Deep Learning Algorithm.","authors":"Wei Ba,&nbsp;Shu-Hao Wang,&nbsp;Can-Cheng Liu,&nbsp;Yue-Feng Wang,&nbsp;Huai-Yin Shi,&nbsp;Zhi-Gang Song","doi":"10.24920/003962","DOIUrl":"https://doi.org/10.24920/003962","url":null,"abstract":"<p><p>Objective To develope a deep learning algorithm for pathological classification of chronic gastritis and assess its performance using whole-slide images (WSIs). Methods We retrospectively collected 1,250 gastric biopsy specimens (1,128 gastritis, 122 normal mucosa) from PLA General Hospital. The deep learning algorithm based on DeepLab v3 (ResNet-50) architecture was trained and validated using 1,008 WSIs and 100 WSIs, respectively. The diagnostic performance of the algorithm was tested on an independent test set of 142 WSIs, with the pathologists' consensus diagnosis as the gold standard. Results The receiver operating characteristic (ROC) curves were generated for chronic superficial gastritis (CSuG), chronic active gastritis (CAcG), and chronic atrophic gastritis (CAtG) in the test set, respectively.The areas under the ROC curves (AUCs) of the algorithm for CSuG, CAcG, and CAtG were 0.882, 0.905 and 0.910, respectively. The sensitivity and specificity of the deep learning algorithm for the classification of CSuG, CAcG, and CAtG were 0.790 and 1.000 (accuracy 0.880), 0.985 and 0.829 (accuracy 0.901), 0.952 and 0.992 (accuracy 0.986), respectively. The overall predicted accuracy for three different types of gastritis was 0.867. By flagging the suspicious regions identified by the algorithm in WSI, a more transparent and interpretable diagnosis can be generated. Conclusion The deep learning algorithm achieved high accuracy for chronic gastritis classification using WSIs. By pre-highlighting the different gastritis regions, it might be used as an auxiliary diagnostic tool to improve the work efficiency of pathologists.</p>","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"36 3","pages":"204-209"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39531639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumonia, Multiple Pulmonary Infarction and Abscess Caused by a Bamboo Stick Accidentally Piercing into Chest: a Case Misdiagnosed as Pulmonary Tuberculosis.","authors":"Peng-Fei Qu,&nbsp;Bao-Liang Bai,&nbsp;Ting Duan,&nbsp;Kai Liu,&nbsp;Jin-Liang Du,&nbsp;Xin Xiong,&nbsp;Peng-Lin Jia,&nbsp;Zhong-Chun Sun,&nbsp;Pu-Ping Lei","doi":"10.24920/003782","DOIUrl":"https://doi.org/10.24920/003782","url":null,"abstract":"<p><p>Computed tomography (CT) examination is the major measure for detecting and diagnosis of foreign bodies in human body. Although CT has high sensitivity in diagnosis of foreign body, some interference factors may still lead to missed diagnosis or misdiagnosis. Here we report a rare case that a bamboo stick accidentally pierced into the left chest of a young man who was drunk and unware of this hurt. The patient experienced cough, chest pain, fever, hemoptysis, and was misdiagnosed as primary and secondary tuberculosis based on chest CT examinations at a local hospital, although no tubercular bacillus detected by sputum smear. He subsequently received anti-tuberculous treatments in the following three years, but no improvement of his symptoms was observed. Until one month before his death, the bamboo stick was detected by spiral CT examination as well as three-dimensional image reconstruction at another hospital. Postmortem examination revealed pneumonia, pulmonary infarction, and abscess as the causes of his death. We analyze the potential reasons of misdiagnosis in this case, aiming to provide reference for the diagnosis and treatment of pulmonary inflammation associated with foreign body in the future.</p>","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"36 3","pages":"252-256"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39531606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances of Artificial Intelligence Application in Medical Imaging of Ovarian Cancers.","authors":"Xu Chen,&nbsp;Xiao-Fei Huo,&nbsp;Zhe Wu,&nbsp;Jing-Jing Lu","doi":"10.24920/003963","DOIUrl":"https://doi.org/10.24920/003963","url":null,"abstract":"<p><p>Ovarian cancer is one of the three most common gynecological cancers in the world, and is regarded as a priority in terms of women's cancer. In the past few years, many researchers have attempted to develop and apply artificial intelligence (AI) techniques to multiple clinical scenarios of ovarian cancer, especially in the field of medical imaging. AI-assisted imaging studies have involved computer tomography (CT), ultrasonography (US), and magnetic resonance imaging (MRI). In this review, we perform a literature search on the published studies that using AI techniques in the medical care of ovarian cancer, and bring up the advances in terms of four clinical aspects, including medical diagnosis, pathological classification, targeted biopsy guidance, and prognosis prediction. Meanwhile, current status and existing issues of the researches on AI application in ovarian cancer are discussed.</p>","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"36 3","pages":"196-203"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39531638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Trimetazidine on Diabetic Patients with Coronary Heart Diseases: A Meta-Analysis of Randomized, Controlled Trials.","authors":"Ye Lin,&nbsp;Zhen Lian Wang,&nbsp;Min Yan,&nbsp;Fei Yu Zhu,&nbsp;Ye Duan,&nbsp;Zhi Qin Sun","doi":"10.24920/003678","DOIUrl":"https://doi.org/10.24920/003678","url":null,"abstract":"<p><p>Objective To explore the therapeutic effects of trimetazidine (TMZ) on diabetic patients with coronary heart diseases.Methods We conducted a comprehensive electronic search of PubMed, EMBASE, and Cochrane databases between the inception dates of databases and May 2019 (last search conducted on 30 May 2019) to identify randomized controlled trials. The evaluation method recommended by Cochrane Collaboration for bias risk assessment was employed for quality assessment. Random or fixed models were used to investigate pooled mean differences in left ventricular function, serum glucose metabolism, serum lipid profile, myocardial ischemia episodes and exercise tolerance with effect size indicated by the 95% confidence interval (<i>CI</i>).Results Additional TMZ treatment contributed to considerable improvement of left ventricular ejection fraction (<i>WMD</i>=4.39, 95%<i>CI</i>: 3.83, 4.95, <i>P</i><0.00001), left ventricular end diastolic diameter (<i>WMD</i>=-3.17, 95%<i>CI</i>: -4.90, -1.44, <i>P</i>=0.0003) and left ventricular end systolic diameter (<i>WMD</i>=-4.69, 95%<i>CI</i>: -8.66, -0.72, <i>P</i>=0.02). TMZ administration also significantly decreased fasting blood glucose (<i>SMD</i>=-0.43, 95%<i>CI</i>: -0.70, -0.17, <i>P</i>=0.001), glycosylated hemoglobin level (<i>WMD</i>=-0.59, 95%<i>CI</i>: -0.95, -0.24, <i>P</i>=0.001), serum level of total cholesterol (<i>WMD</i>=-20.36, 95%<i>CI</i>: -39.80, -0.92, <i>P</i>=0.04), low-density lipoprotein cholesterol (<i>WMD</i>=-20.12, 95%<i>CI</i>: -32.95, -7.30, <i>P</i>=0.002) and incidence of myocardial ischemia episodes (<i>SMD</i>=-0.84, 95%<i>CI</i>: -1.50, -0.18, <i>P</i>=0.01). However, there were no significant differences in serum triglyceride level, high-density lipoprotein cholesterol, exercise tolerance between the TMZ group and the control group. Conclusion TMZ treatment in diabetic patients with coronary heart disease is effective to improve cardiac function, serum glucose and lipid metabolism and clinical symptoms.</p>","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"35 3","pages":"226-238"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38516379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Short-term Dual Antiplatelet Therapy after Implantation of Second-generation Drug-eluting Stents: A Meta-analysis and Systematic Review.","authors":"Peisen Huang,&nbsp;Yuan Yu,&nbsp;Xikun Han,&nbsp;Yuejin Yang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objective The benefit of short-term dual antiplatelet therapy (DAPT) following second-generation drug-eluting stents implantation has not been systematically evaluated. To bridge the knowledge gap, we did a meta-analysis to assess the efficacy of ≤6 months versus ≥12 months DAPT among patients with second-generation drug-eluting stents.Methods We searched online databases and identified randomized controlled trials that assess the clinical impact of short-term DAPT (≤6 months) published before March 3, 2016. The efficacy endpoints included the incidence of all-cause death, myocardial infarction, cerebrovascular accidents, and definite or probable stent thrombosis. Safety endpoint defined as major bleeding was also evaluated and discussed.Results We included 5 trials that randomized 9473 participants (49.8%, short-term DAPT duration vs. 50.2%, standard duration). A total of 9445 (99.7%) patients reported the efficacy endpoints, and the safety endpoint was available from 4 studies (n=8457). There was no significant difference in efficacy endpoints between short-term and standard DAPT duration (≥12 months) [risk ratio (RR) 0.96; 95% confidence intervals (CI), 0.80-1.15]. Short-term DAPT duration did not significantly increase the individual risk of all-cause death, myocardial infarction, cerebrovascular accidents, or definite or probable stent thrombosis. Although short-term DAPT obviously reduced risk of major bleeding compared with standard DAPT (RR 0.53; 95% CI, 0.29-0.96), significant publication bias was found when accessing the safety endpoint of the 4 studies (Egger's test, P=0.009).Conclusions The efficacy of short-term DAPT was comparable with that of standard duration DAPT. DAPT less than 6 months may be appropriate for patients receiving second-generation drug-eluting stents implantation.</p>","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"32 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2017-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34904724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-analysis of aspirin-heparin therapy for un-explained recurrent miscarriage.","authors":"Ling Tong, Xianjiang Wei","doi":"10.1016/S1001-9294(17)30007-X","DOIUrl":"https://doi.org/10.1016/S1001-9294(17)30007-X","url":null,"abstract":"","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"75 1","pages":"239-246"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74430325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Sleep Deprivation on Coronary Heart Disease.","authors":"Rong Yuan, Jie Wang, Li-li Guo","doi":"10.1016/S1001-9294(17)30008-1","DOIUrl":"https://doi.org/10.1016/S1001-9294(17)30008-1","url":null,"abstract":"","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"12 1","pages":"247-253"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88401838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudohyperkalemia with Myelofibrosis after Splenectomy.","authors":"Shengli Liu, Luwei Zhang, Jun Tian","doi":"10.1016/S1001-9294(17)30010-X","DOIUrl":"https://doi.org/10.1016/S1001-9294(17)30010-X","url":null,"abstract":"","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"63 1","pages":"258-260"},"PeriodicalIF":0.0,"publicationDate":"2016-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84066284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frontal Absence Seizures: Clinical and EEG Analysis of Four Cases.","authors":"L. Dong, Q. Lu, Yan Huang, Xiangqin Zhou","doi":"10.1016/S1001-9294(17)30009-3","DOIUrl":"https://doi.org/10.1016/S1001-9294(17)30009-3","url":null,"abstract":"","PeriodicalId":10186,"journal":{"name":"Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih","volume":"622 1","pages":"254-7"},"PeriodicalIF":0.0,"publicationDate":"2016-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77088048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}