Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics最新文献

Analysis on Intestinal Microbiota in Rheumatoid Arthritis 类风湿关节炎患者肠道菌群分析

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011197100003443

R. Peng

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Changes of Eukaryotes Microorganism Structures in Soil during Continuous Cropping of Lettuce 生菜连作期间土壤真核生物微生物结构的变化

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011217900003443

Xinyu Wang, Qingwen Li, Jie Hong, Zhidi Chen, Yi-Kai Gao, Xinxin Yi, Xiuzhi Gao

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Determination of the Quality and Nutrition of Seven Edible Fungi 七种食用菌品质与营养的测定

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011190000003443

Wen-yan Lv, Lanlan Yang, Xin Ma, Tian Tian, Sanlin Wu, Yuping Fan

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Applications of Metal Organic Frameworks in Drug Delivery and Therapy 金属有机骨架在药物传递和治疗中的应用

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011216100003443

Yubo Li, Guanlin Peng, Yuezhou Yu

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Potentials of the Dry Granulation by Roller Compaction 碾压干燥造粒的电位

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011202700003443

Yujie Zhang

{"title":"Potentials of the Dry Granulation by Roller Compaction","authors":"Yujie Zhang","doi":"10.5220/0011202700003443","DOIUrl":"https://doi.org/10.5220/0011202700003443","url":null,"abstract":": The latest trends in the field of pharmaceutical engineering are regarding roller compaction. Roller compaction technology is a well-established strategy particularly involved in the medical industry. This developing process has a great impact on the manufacturing of oral solid dosage forms while containing high-quality active pharmaceutical ingredients (API). When the medical industry tends to develop a tablet, there are three basic processing routes that have been considered: direct compression, dry granulation, and wet granulation. Among these three high-efficiency productive ways, dry granulation is a process that compresses powdery ingredients into tablets without adding any liquid solution. Dry granulation is carried out using either slugging or roller compaction techniques. This pharmaceutic process has potentials for drug development as it has been proved to continuously manufacture tablets by working with compaction machines. Roller compaction employed to dry granulation can provide more advantages compared with other processing methods. However, there are still have some challenges that this technology and researchers need to face. Improvements on the dry granulation by roller compaction technology would give a great contribution to drug development and goods production.","PeriodicalId":101862,"journal":{"name":"Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129559168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Anticancer Effects and Mechanisms of Artemisinin and Its Derivatives on Hematological Malignancies 青蒿素及其衍生物对血液恶性肿瘤的抗癌作用及其机制

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011377300003443

Xinlei An, Qiao Huang, Yuehua Wu

{"title":"Anticancer Effects and Mechanisms of Artemisinin and Its Derivatives on Hematological Malignancies","authors":"Xinlei An, Qiao Huang, Yuehua Wu","doi":"10.5220/0011377300003443","DOIUrl":"https://doi.org/10.5220/0011377300003443","url":null,"abstract":": Traditional Chinese medicine believes that artemisinin (ART) could treat malaria which are extracted from artemisia. Modern medicine found that except the use of curing malaria, artemisinin and its derivatives also show anticancer activities in vitro and in vivo by reducing the proliferation, migration, invasion, tumorigenesis and metastasis of cancer cells. As the components of natural plants, artemisinin and its derivatives demonstrated multi-specific manner in the treatment of hematological malignancies. The major mechanisms of effects of artemisinin and its derivatives on anticancer activities include induction of apoptosis, inhibition of angiogenesis, inhibition of proliferation, etc., through regulating multiple pathways, such as JNK, KDR / Flk-1, MAPK, STAT3 and Wnt/β-catenin signalling pathways. This review discusses the anticancer activity of artemisinin, artesunate and dihydroartemisinin (DHA) in the treatment of hematological malignancies, and from which it is demonstrated that ART and its derivatives are effective in vitro and in vivo. Future research is required in this promising field of cancer drug discovery.","PeriodicalId":101862,"journal":{"name":"Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129652979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large Scale Virtual Screening for Finding Inhibitor against the RNA-dependent RNA Polymerase from Herbal Medicine for SARS-Cov-2 Therapy 从草药中寻找RNA依赖性RNA聚合酶抑制剂用于治疗SARS-Cov-2的大规模虚拟筛选

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011313300003443

Xiaogang Liu, Zirong Liang, Shiye Wu, Y. Wang, Binquan Gou

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Afferent GPi and Efferent from RMTg to VTA of LHb for Reward Omission 奖赏遗漏对LHb RMTg传入GPi和传入VTA的影响

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011296800003443

Z. Zu

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Botulinum Toxin’s using in Treatment of Cerebral Palsy 肉毒毒素在脑瘫治疗中的应用

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011252400003443

Haitao Tian, Zehao Wu, Chenxu Yang

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Comparative Study on Antioxidant Properties of Various Solvent Extracts Relating to Indocalamus tessellatus Leaves of Agricultural Tourism Products 农业旅游产品梧桐叶不同溶剂提取物抗氧化性能比较研究

Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics Pub Date : 1900-01-01 DOI: 10.5220/0011382400003443

Shenglang Jin, Fei Que

{"title":"Comparative Study on Antioxidant Properties of Various Solvent Extracts Relating to Indocalamus tessellatus Leaves of Agricultural Tourism Products","authors":"Shenglang Jin, Fei Que","doi":"10.5220/0011382400003443","DOIUrl":"https://doi.org/10.5220/0011382400003443","url":null,"abstract":": The rapid development of rural tourism in China has become an important force in China's tourism industry. Rural tourism is increasingly becoming an effective carrier to solve the problem of urban-rural integration and the construction of new countryside, and the production, development and marketing of agricultural products are gradually becoming a key selling point of rural tourism. As a tourist agricultural product, Indocalamus tessellatus leaves were extracted by ethanol, petroleum ether and water respectively. Three different extracts revealed different results of each experiment. The ethanol extract with the most total phenol content is the most effective antioxidant in all experiments. The effects of five different pH values on the antioxidant activities at two diverse temperatures were also studied. The antioxidant activity of the extract kept the temperature at 40 ℃. It reached the maximum value at pH 7, and decreased gradually after hiding at 5 ℃ for 30 days ( p <0.05). The results showed that Indocalamus leaf has significant antioxidant activity, so it can be used as a potential source of natural antioxidants in the food industry.","PeriodicalId":101862,"journal":{"name":"Proceedings of the 11th International Conference on Biomedical Engineering and Bioinformatics","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133106684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0