BOHR International Journal of Current Research in Optometry and Ophthalmology最新文献

{"title":"The Glymphatic System and New Etiopathogenic Hypotheses Concerning Glaucoma Based on Pilot Study on Glaucoma Patients Who Underwent Osteopathic Manipulative Treatment (OMT)","authors":"D. Paoli, L. Michelin, F. Vassallo, Luigi Ciullo, P. Brusini, L. Torelli","doi":"10.54646/bijcroo.007","DOIUrl":"https://doi.org/10.54646/bijcroo.007","url":null,"abstract":"Purpose Malfunction of the lymphatic or glymphatic system recently shown in the brain, seems to play an important role in central neurodegenerative pathologies through a build-up of neurotoxins. Recent studies have shown functional links between aqueous humour and cerebrospinal fluid via the glymphatic system, offering new perspectives and unifying theories on the vascular, biomechanical and biochemical causes of chronic and open angle glaucoma (POAG). The aim of this randomized pilot study is to compare the variations in intraocular pressure between 20 cases of compensated POAG under pharmacological therapy and 20 glaucoma patients undergoing osteopathic treatment, hypothesizing that this manipulation can influence intraocular pressure. Materials and Methods The 40 patients under study, all covered by the Helsinki convention, were randomly divided into 2 groups (treated group or TG and control group or CG). The 40 patients were chosen from compensated glaucoma sufferers, who required neither changes in therapy nor operations which would affect their eye pressure which was measured both before and after manipulative osteopathic treatment scheduled into 4 sessions at intervals of 7.3 and 150 days, then compared with the control group (20 patients) who were undergoing pharmacological treatment only. Results The average IOP in the TG was compared with the CG throughout the entire treatment cycle showing a statistically inconclusive reduction in the right eye RE P-value (0.0561), while for the left eye a significant effect was shown LE (0.0073). The difference between the reduction in IOP between TG and CG was observable 10 months after the first session or rather 5 months after the last, and demonstrable during a check-up 13 months after the beginning of the study, or rather 8 months in absence of treatment with a highly significant statistical p-value (0.000434). Conclusions This study has shown that manipulative osteopathic treatment can affect intraocular pressure after each session and that the pressure is significantly lower even months after the last treatment session.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128243035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of “Retinoblastoma center” in A Tertiary Eye Care Center of Bangladesh – A New Hope for Retinoblastoma Patients","authors":"Rani Roy Soma","doi":"10.54646/bijcroo.016","DOIUrl":"https://doi.org/10.54646/bijcroo.016","url":null,"abstract":"Retinoblastoma is the most common primary intraocular tumor in children with an incidence of 1:16,000 to 18,000 live birth. Worldwide newly detected cases per year are about 8000 and in India above 1400. It represents 11% of cancer that develops in the first year of life. The revolutionary management strategy has increased the survival rate of retinoblastoma above 95% in developed countries, and this rate is the highest among all pediatric cancers. But still, it is deadly cancer worldwide. Survival from retinoblastoma based on income >90% vs. 40% (in high to low-income countries). The incidence of metastasis is more in lower-income countries (32% vs. 12% in middle-income). Notably, Forty-three percent of the world’s estimated cases reside in only 6 countries in Asia (China, Indonesia, Philippines, India, Pakistan, and Bangladesh). The mortality rate varies on different continents. Worldwide estimated death from retinoblastoma is more than 40%, and most of them are from Asia and Africa. Bangladesh is one of the developing countries in the South-East Asia region, and retinoblastoma constitutes 83% of all pediatric cancer under 4 years of age. For proper management of retinoblastoma with an international standard, the establishment of a retinoblastoma center consisting of ocular oncologist, clinical oncologist, radiation oncologist, pediatrician, oculoplastic surgeon, retina specialist, pediatric ophthalmologist, and ocularist is needed. Management includes proper diagnosis, treatment of the disease, genetic counseling, regular follow-up, rehabilitation of survivors, and screening of siblings. Chittagong Eye Infirmary & Training Complex is a tertiary eye care center and one of the referral centers of Bangladesh and is treating retinoblastoma since its inception. Due to the demand of time, the hospital has been reorganized with various facilities to serve retinoblastoma patients with a team approach in 2017. From January 2017 to March 2022, a total of 304 patients were diagnosed. Among them, 132 received vincristine, etoposide, and carboplatin (VEC) chemotherapy from this center, and 79 underwent enucleation with the long optic nerve. Besides treatment, the hospital is conducting sibling screening, visual and psycho-social rehabilitation for the RB survivors, and community awareness programs.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"88 35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130793241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobility Performance in Retinitis Pigmentosa Under Different Lighting Simulation Conditions","authors":"R. Omar","doi":"10.54646/bijcroo.010","DOIUrl":"https://doi.org/10.54646/bijcroo.010","url":null,"abstract":"This study examined the mobility performance in retinitis pigmentosa (RP) under different simulation lighting conditions. A total of twenty-one subjects with RP and twenty-one age-matched controls were enrolled. Preferred Walking Speed (PWS) were determined using a simple mobility course at 61 cd/m2 while Percentage of Preferred Walking Speed (PPWS) and error score were determined at five different illumination level which were 62, 47, 20, 6 and 1 cd/m2 using a complex mobility course. RP and normal people had similar mobility performances in simple mobility situations at a constant high light level. In lower light levels as well as in complex mobility situations, RP subjects demonstrated markedly reduced mobility performance. The relationship between PPWS and luminance was linear, with the PPWS decreasing significantly when the mobility course luminance dropped below the illumination of 20 cd/m2 . The Error score was also noted to be linearly related to log luminance. A luminance level of 20 cd/m2 may provide a useful decision point in setting indoor light levels for clinical mobility courses.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114223593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Churg-Strauss syndrome presented as Pseudo-Foster-Kennedy syndrome: a case report","authors":"S. Roy, S. Biswas","doi":"10.54646/bijcroo.2023.29","DOIUrl":"https://doi.org/10.54646/bijcroo.2023.29","url":null,"abstract":"A 52-year-old woman with bronchial asthma, frequent sneezing, and a skin lesion has suddenly developed poor vision for 15 days in the left eye. Her presenting vision was 6/18 and perception of light was positive in the right and left eyes, respectively, with mild pallor in the right optic disc and disc swelling in the left eye. She had a high eosinophil count, positive ANCA, and a skin biopsy in favor of Churg-Strauss disease. The patient was diagnosed with left optic neuropathy as a result of arteritis, which is a component of Churg-Strauss syndrome (CSS), and was treated with Inj. Methylprednisolone pulse therapy, followed by oral prednisolone but preceded to no perception of light in the left eye after 7 days of follow-up. Although CSS is a rare disease, routine checkup by an ophthalmologist can save vision and identify the high-risk group for proper referral to prevent unwanted morbidity and mortality.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129365259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Globe Subluxation in a Neonate: A Case Report with Literature Review","authors":"S. Roy, Md. Asrarul Hoque","doi":"10.54646/bijcroo.026","DOIUrl":"https://doi.org/10.54646/bijcroo.026","url":null,"abstract":"Globe subluxation is a medical emergency and a frightening condition. The spontaneous subluxation is the rarest of the subluxations, with fewer than 40 cases reported to date. This condition is extremely rare in children, with the most recent reported age being 8 months. However, Crouzon syndrome in infants is also less reported. Here we report a case of neonatal Crouzon syndrome with spontaneous globe subluxation and its surgical management.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133293255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotypic Analysis of A Case of ‘3MC Syndrome’ with Review of Literature","authors":"Rani Roy Soma, Kader Md. Sazzad","doi":"10.54646/bijcroo.014","DOIUrl":"https://doi.org/10.54646/bijcroo.014","url":null,"abstract":"3MC syndrome is a very rare entity. It’s prevalence is unknown but most cases are reported from Middle East. First case was reported in 1978 and named as Michel syndrome and recently with other three syndromes together these syndromes are named as 3 MC syndrome. All are autosomal recessive disorder and reported from both consanguineous and non- consanguineous parents. Here we phenotypically analyzed a case presented with the features of blepharophimosis syndrome associated with craniosynostosis suggestive of Mischel syndrome which is a part of ‘3 MC syndrome’.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134262122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Panophthalmitis After Aurolab Aqueous Drainage Implant (AADI) in Refractory Glaucoma with Vogt-Koyanagi-Harada Syndrome (VKH): A Case Report","authors":"Md Iftekher Iqbal, S. Kabir, B. Sarker","doi":"10.54646/bijcroo.022","DOIUrl":"https://doi.org/10.54646/bijcroo.022","url":null,"abstract":"This case of Vogt-Koyanagi-Harada (VKH) disease underwent Aurolab Aqueous Drainage Implant (AADI) for refractory glaucoma. Later, developed postoperative (2 months) panophthalmitis characterized by sudden visual loss, moderate pain, redness, and purulent discharge. Systemic, topical, and intravitreal antibiotic therapy was started immediately, and evisceration was performed.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129802086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management Challenge: A Case of Aniridia and Aphakia with Secondary Glaucoma in Sclerokeratoplasty","authors":"S. Thatte, Komal Jaiswal, Radhika Maheshwari","doi":"10.54646/bijcroo.027","DOIUrl":"https://doi.org/10.54646/bijcroo.027","url":null,"abstract":"A patient presented to us with post-infectious keratitis and a large anterior staphyloma in the left eye with vision as low as only the perception of light and accurately determining the projection of rays. A B-scan showed no abnormality in the posterior segment. Sclerokeratoplasty with an 11-mm graft with aniridia and aphakia was done. On 4 weeks of follow-up, intraocular pressure (IOP) was 39 mmHg on applanation tonometry, for which medical management was tried using a combination regime that was insufficient, following which a series of management approaches like trabeculectomy and Ahmed glaucoma valve (AGV) implant was done (in superotemporal quadrant). Unfortunately, recurrent exposures of the AGV tube were encountered, which were managed using different graft materials one after the other but were unsuccessful. Ultimately, AGV explantation and reinsertion at another site (in inferotemporal quadrant) was tried, which led to salvaging the eye with well controlled IOP, clear graft, and good visual function (best corrected visual acuity of 6/12p with +12.00/+1.50 × 90◦ ). The purpose of this article was to highlight that despite multiple complications encountered in a single case, a careful sequential approach, good surgical skills, and a never giving up attitude lead to excellent results.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128913354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Autologous Blood Clot in Primary Pterygium Surgery Compared With Suture Technique in a Tertiary Hospital of Bangladesh","authors":"Md Iftekher Iqbal, Fariah Osman, Md. Firoz Kabir, S. Parvez","doi":"10.54646/bijcroo.021","DOIUrl":"https://doi.org/10.54646/bijcroo.021","url":null,"abstract":"Purpose: The aim of this study is to assess the efficacy among patients undergoing pterygium excision and conjunctival autograft utilizing autologous blood or sutures. Methods: A randomized controlled trial of 1 year and 5 months, with 60 eyes from 60 patients having primary nasal pterygium. As indicated by inclusion criteria, they were chosen and randomized into two arms for conjunctival autograft: treated arm A (30) with autologous blood and arm B (30) with stitches (10-0 monofilament nylon). Preoperative and postoperative results were assessed and analyzed statistically. Follow-up was done at first, seventh, 1-month, 3-month, and half-year postoperative days. Resulting factors were total surgical time, postoperative comfort, graft stability, and recurrence. Results: 60 patients; mean age of 46.77 ± 7.04 (SD) in arm A (30) and 46.17±7.53 (SD) in arm B (30). In arm A, 22 males (73.3%) and 8 females (26.7%) where arm B had 20 males (66.7%) and 10 females (33.3%). Total surgical time in arm A was 24.73 ± 3.69 (SD) minutes and in arm B was 32.23 ± 4.59 (SD) minutes (p < 0.001). Follow-up at the 1st and 7th POD showed significant discomfort in arm B (mean ranks 41.82 and 40.62) compared to arm A (mean ranks 19.18 and 20.38), respectively (p < 0.001). At 1st POD, only 3 (10%) graft retractions in arm A. Within 6 months of follow-up, all grafts were stable; 1 (3.3%) recurrence and 1 (3.3%) granuloma in arm B only. Conclusion: In primary pterygium surgery, autologous blood showed excellent postoperative results with no recurrence and reduced surgical time. So, it seems to be an effective surgical means to treat primary pterygium.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130941572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dried Scleral Patch Graft: A Temporary Measure of Corneal Perforation Prior Keratoplasty-Two Case Reports","authors":"Biswas Sujit Kumar, A. S. M. Mahbubul Alam, Ahmed Ria Tanjila, Matin Bhuiyan Abdul","doi":"10.54646/bijcroo.013","DOIUrl":"https://doi.org/10.54646/bijcroo.013","url":null,"abstract":"Aim: To describe the temporary management of corneal perforation by using dried sclera patch graft prior keratoplasty when donor tissue not available. Case report: Two cases of corneal perforation (>2mm) of various causes presented with severely decreased vision and shallow anterior chamber and soft eye ball. Both needed immediate therapeutic keratoplasty to save the globe and restore the vision. Due to unavailability of donor cornea, both patients were surgically managed with dried scleral patch graft temporarily to save the globe. Both patients underwent therapeutic keratoplasty one moth and one and half months respectively. Both patients gained better vision (6/18 and 6/24 respectively), quiet anterior chamber and no secondary glucoma after 6 month of keratoplasty. Conclusion: Dried sclera patch graft is a good option for temporary management of corneal perforation of various causes until a donor cornea is available. These patch grafts prevent ocular hypotony, posterior synechiea and secondary glucoma.","PeriodicalId":101752,"journal":{"name":"BOHR International Journal of Current Research in Optometry and Ophthalmology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124934063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}