ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.22.05512-7
Dina Jalalvand, Pooneh Dehghan, Hamidreza HAGHIGHAT KHAH, Mehdi Eshaghzadeh, Mahdi Mehrian
{"title":"CT scan and clinical characteristics in COVID-19 patients with and without systemic lupus erythematosus","authors":"Dina Jalalvand, Pooneh Dehghan, Hamidreza HAGHIGHAT KHAH, Mehdi Eshaghzadeh, Mahdi Mehrian","doi":"10.23736/s0394-9508.22.05512-7","DOIUrl":"https://doi.org/10.23736/s0394-9508.22.05512-7","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138608719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.23.05538-9
Mulkyawan Bahrun, Ibrahim Labeda, Mappincara Mappincara, Joko Hendarto, R. E. Lusikooy, Warsinggih Warsinggih, Samuel Sampetoding, M. I. Kusuma, J. A. Uwuratuw, Erwin Syarifuddin, Muhammad Faruk
{"title":"Plasma D-dimer and urine D-dimer are associated with resectability of pancreatic cancer","authors":"Mulkyawan Bahrun, Ibrahim Labeda, Mappincara Mappincara, Joko Hendarto, R. E. Lusikooy, Warsinggih Warsinggih, Samuel Sampetoding, M. I. Kusuma, J. A. Uwuratuw, Erwin Syarifuddin, Muhammad Faruk","doi":"10.23736/s0394-9508.23.05538-9","DOIUrl":"https://doi.org/10.23736/s0394-9508.23.05538-9","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138615108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.23.05530-4
Francesco Brucchi, Salvatore Barbaro, Davide Ferrara, G. Faillace
{"title":"Surgical management of wide pilonidal disease with perianal abscess and gradual closure of the defect using DermaClose device","authors":"Francesco Brucchi, Salvatore Barbaro, Davide Ferrara, G. Faillace","doi":"10.23736/s0394-9508.23.05530-4","DOIUrl":"https://doi.org/10.23736/s0394-9508.23.05530-4","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138621332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.23.05537-7
Ferdinandes Ferdinandes, R. E. Lusikooy, J. A. Uwuratuw, Joko Hendarto, Ibrahim Labeda, Warsinggih Warsinggih, Mappincara Mappincara, Samuel Sampetoding, M. Dani, M. I. Kusuma, Erwin Syarifuddin, Muhammad Faruk
{"title":"The correlation between tenascin C levels and clinical stage in colorectal cancer patients","authors":"Ferdinandes Ferdinandes, R. E. Lusikooy, J. A. Uwuratuw, Joko Hendarto, Ibrahim Labeda, Warsinggih Warsinggih, Mappincara Mappincara, Samuel Sampetoding, M. Dani, M. I. Kusuma, Erwin Syarifuddin, Muhammad Faruk","doi":"10.23736/s0394-9508.23.05537-7","DOIUrl":"https://doi.org/10.23736/s0394-9508.23.05537-7","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138624281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.21614/chirurgia.2023.v.118.i.6.p.584
Cosmin Victor Ene, Ca Ta Lin Andrei Bulai, Petrisor Geavlete, Razvan Ionut Popescu, Ileana Adela Vacaroiu, Dragoş Eugen Georgescu, Isabela Voichita Isaconi, Ma da Lina Andreea Munteanu, Corina Daniela Ene, Adrian Militaru, Bogdan Geavlete, Razvan Multescu
{"title":"New Insights into Lynch Syndrome: A Narrative Review.","authors":"Cosmin Victor Ene, Ca Ta Lin Andrei Bulai, Petrisor Geavlete, Razvan Ionut Popescu, Ileana Adela Vacaroiu, Dragoş Eugen Georgescu, Isabela Voichita Isaconi, Ma da Lina Andreea Munteanu, Corina Daniela Ene, Adrian Militaru, Bogdan Geavlete, Razvan Multescu","doi":"10.21614/chirurgia.2023.v.118.i.6.p.584","DOIUrl":"10.21614/chirurgia.2023.v.118.i.6.p.584","url":null,"abstract":"<p><p>Lynch syndrome, characterized by DNA mismatch repair deficiency, represents a significant paradigm among cancer predisposition syndromes and is notably associated with heightened susceptibility to various cancers, particularly colorectal and endometrial malignancies. The primary aim of this research paper is to scrutinize specific associations and delve into the underlying molecular mechanisms of Lynch syndrome. Genetic alterations in MMR genes, including MLH1, MSH2, MSH6, PMS2, and EPCAM, compromise DNA repair mechanisms, predisposing affected individuals to a spectrum of malignancies. This paper comprehensively investigates current screening methodologies and preventive measures tailored for individuals identified or at risk of Lynch syndrome. The integration of advanced sequencing technologies and refined bioinformatics tools has significantly improved mutation detection accuracy, facilitating precise identification of mutation carriers and their at-risk relatives. Moreover, this review emphasizes the evolving diagnostic landscape, which have revolutionized the identification of potential mutation carriers. The structured diagnostic algorithm, incorporating clinical criteria, tumor testing, and genetic analysis, plays a pivotal role in systematically identifying and managing individuals with Lynch syndrome. While the well-established association of Lynch syndrome with colorectal and endometrial cancers is recognized, emerging evidence suggests an increased risk for other types of malignancies. A crucial aspect of this literature review is to extensively analyze the less commonly acknowledged correlation between Lynch syndrome and prostate or testicular malignancies. Understanding these correlations holds significant importance in guiding tailored screening protocols and preventive strategies for individuals carrying Lynch syndrome-associated genetic mutations. The comprehensive assessment of this diverse spectrum of cancers underscores the necessity for tailored surveillance strategies and multidisciplinary approaches to effectively manage and mitigate risks in individuals harboring Lynch syndrome-associated genetic alterations.</p>","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139477948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.23.05570-5
Mohamud M Aden, A. Kivelä, Lauri M. Taipale, Tom M. Scheinin, S. Rasilainen
{"title":"Risk factors for mortality and end-colostomy in patients with sigmoid volvulus managed by sigmoid resection","authors":"Mohamud M Aden, A. Kivelä, Lauri M. Taipale, Tom M. Scheinin, S. Rasilainen","doi":"10.23736/s0394-9508.23.05570-5","DOIUrl":"https://doi.org/10.23736/s0394-9508.23.05570-5","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138623687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.21614/chirurgia.2023.v.118.i.6.p.596
Alexandru Ilie-Ene, Victor Eşanu, Vlad Făgărăşan, Victor Petru Toşa, George-Călin Dindelegan
{"title":"Cyanoacrylate Adhesives Used for Topical Hemostasis A Systematic Review.","authors":"Alexandru Ilie-Ene, Victor Eşanu, Vlad Făgărăşan, Victor Petru Toşa, George-Călin Dindelegan","doi":"10.21614/chirurgia.2023.v.118.i.6.p.596","DOIUrl":"10.21614/chirurgia.2023.v.118.i.6.p.596","url":null,"abstract":"<p><p><b>Introduction:</b> In this systematic review the topical hemostatic properties of Cyanoacrylate Adhesives (CA) have been studied. \u0000\u0000<b>Material and Method:</b> Four major scientific databases (Embase, Scopus, PubMed, and Web of Science) were inquired, retrieving reviews and meta-analysis studies, clinical trials, experimental studies, and case reports that presented data regarding topical hemostasis and CA. English written articles, published in the last 10 years were collected. The last search was performed on the 1st of August 2023. Risk of bias in the included studies was assessed using study-design specific, evidence-based tools. \u0000\u0000<b>Results:</b> A summary focused on relevant information of all included studies was drafted and the results of the studies have been synthetized and compared. A total of 42 studies have been included in the review (14 reviews and meta-analysis, 11 clinical trials, 9 experimental studies and 8 case reports). CA exhibited important topical hemostatic capabilities, comparable with other performant hemostatic materials. Although most included studies concluded that CA were potent topical hemostatic agents, the high level of heterogeneity among the studies prevented us from performing a meta-analysis. \u0000\u0000<b>Conclusion:</b> The results of this review show that CA-based compounds represent an important line of research towards the perfect hemostatic material.</p>","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139477927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.23.05527-4
G. Yankov, M. Alexieva, Nikolay Yanev, Silvia Ivanova, E. Mekov
{"title":"A complicated course of treatment in a patient with adenosquamous lung cancer","authors":"G. Yankov, M. Alexieva, Nikolay Yanev, Silvia Ivanova, E. Mekov","doi":"10.23736/s0394-9508.23.05527-4","DOIUrl":"https://doi.org/10.23736/s0394-9508.23.05527-4","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138617277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.23736/s0394-9508.23.05651-6
Luigi Tarallo, Marco Montemagno, Matilde Delvecchio
{"title":"Fractures of the elbow: current concepts and management","authors":"Luigi Tarallo, Marco Montemagno, Matilde Delvecchio","doi":"10.23736/s0394-9508.23.05651-6","DOIUrl":"https://doi.org/10.23736/s0394-9508.23.05651-6","url":null,"abstract":"","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138623875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChirurgiaPub Date : 2023-12-01DOI: 10.21614/chirurgia.2023.v.118.i.6.p.654
Vlad Paic, Petru Adrian Radu, Dan Cartu, Dragos Garofil, Anca Tigora, Mihai Zurzu, Mircea Bratucu, Valentin Georgescu, Costin Pasnicu, Raluca Gabriela Ioan, Florian Popa, Traean Burcos, Valeriu Surlin, Victor Strambu, Razvan Daniel Chivu
{"title":"Open and Laparoscopic Surgical Approache in Incisional Hernias: A Descriptive Analysis.","authors":"Vlad Paic, Petru Adrian Radu, Dan Cartu, Dragos Garofil, Anca Tigora, Mihai Zurzu, Mircea Bratucu, Valentin Georgescu, Costin Pasnicu, Raluca Gabriela Ioan, Florian Popa, Traean Burcos, Valeriu Surlin, Victor Strambu, Razvan Daniel Chivu","doi":"10.21614/chirurgia.2023.v.118.i.6.p.654","DOIUrl":"10.21614/chirurgia.2023.v.118.i.6.p.654","url":null,"abstract":"<p><p><b>Background:</b> Incisional hernias, occurring in 10-20% of patients post-abdominal surgery, significantly affect patient quality of life and healthcare systems. This study analyses two hernia repair methods: laparoscopic intraperitoneal onlay mesh (IPOM) and open on-lay hernioplasty. Key analysis factors include operative time, postoperative pain, complications, length of hospital stay, recovery speed, and recurrence rates, with the goal of identifying the most effective and beneficial approach for patients. <b>Methods:</b> We conducted a retrospective study on 70 patients with postoperative parietal defects at the Dr Carol Davila Clinical Nephrology Hospital, Bucharest, from January 2018 to December 2021. Patients underwent either laparoscopic IPOM (42 patients) or open hernioplasty (28 patients) for uncomplicated incisional hernia repair. We analyzed demographic data, comorbidities, defect size and location, previous surgeries, and surgical outcomes. <b>Results:</b> The laparoscopic group had a slightly shorter operative time and significantly lower postoperative pain levels, as assessed by the Visual Analog Scale. The laparoscopic approach also resulted in shorter hospital stays and quicker return to routine activities. Complications, such as seroma and hematoma, were more common in the open surgery group, but no wound infections or prosthesis rejections were observed in either group. Notably, the open surgery group showed a higher recurrence rate (11 %) compared to none in the laparoscopic group within a one-year follow-up. Conclusion: Laparoscopic IPOM for incisional hernia repair shows benefits over open hernioplasty, with less pain, shorter hospitalization, faster recovery, and lower recurrence. Its growing preference and potential for further research are highlighted.</p>","PeriodicalId":10171,"journal":{"name":"Chirurgia","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139477877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}