Ovarian Carcinoma: A Single-Centre Eight-Year Case-Series Study with Survival Analysis.

IF 0.8 Q4 SURGERY
Chirurgia Pub Date : 2024-08-01 DOI:10.21614/chirurgia.3025
George Daniel Subtirelu, Andreea Steriu, Eugen Bratucu
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引用次数: 0

Abstract

Introduction: This research describes an eight-year case-series of ovarian carcinoma by surgical (pTNM) staging and surgical procedure, explores the characteristics of ovarian surface epithelial cell (OSEC) tumours by histopathological type in a single centre of reference. Material and Methods: survival analysis with overall survivor probabilities for n=263 patients for 12 months and 60-month tumour free survival status (TFS). Results by staging (pTNM stage classification), histotype and for poor surgical candidate (PSC) status are shown. Histotype high grade serous carcinoma (HGSC) was the most frequently diagnosed type (63%). Results: 12-month survivor probabilities according to histotype, rank as follows: clear cell carcinoma (CCC) - 14%; rare carcinoma (RC) - 15%; carcinosarcoma (CS) - 29%; HGSC - 46%; low grade serous carcinoma (LGSC) - 74%; endometrioid carcinoma (EC) - 79%; mucinous carcinoma (MC) - 80% and borderline tumours (BLT) - 94%. At 60 months results are: RC and MC - 0%; CCC - 14%; HGSC - 16%; CS - 29%; LGSC - 62%; EC - 66%; and BLT - 94%. Overall median survival time is 26 months (CI95% 15 to 37); and 20 months when BLT excluded (CI95% CI 15 to 25). Conclusions: These results may guide further research for the OSEC pathology and its histotypes.

卵巢癌:一项为期八年的单中心病例系列研究及生存分析。
导言:本研究描述了一项为期八年的卵巢癌病例系列研究,通过手术(pTNM)分期和手术过程,探讨了单个参考中心卵巢表面上皮细胞(OSEC)肿瘤的组织病理学类型特征。材料与方法:对 263 名患者进行 12 个月和 60 个月无瘤生存状态(TFS)的总生存概率生存分析。结果按分期(pTNM 分期分类)、组织型和不良手术候选者(PSC)状态显示。组织型高级别浆液性癌(HGSC)是最常见的诊断类型(63%)。结果根据组织类型,12 个月的存活概率排名如下:透明细胞癌 (CCC) - 14%;罕见癌 (RC) - 15%;癌肉瘤 (CS) - 29%;高级别浆液性癌 (HGSC) - 46%;低级别浆液性癌 (LGSC) - 74%;子宫内膜样癌 (EC) - 79%;粘液腺癌 (MC) - 80%;边缘性肿瘤 (BLT) - 94%。60 个月的结果如下RC和MC--0%;CCC--14%;HGSC--16%;CS--29%;LGSC--62%;EC--66%;BLT--94%。总体中位生存时间为 26 个月(CI95% 15 至 37);如果不包括 BLT,则为 20 个月(CI95% CI 15 至 25)。结论:这些结果可指导对 OSEC 病理学及其组织型的进一步研究。
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来源期刊
Chirurgia
Chirurgia Medicine-Surgery
CiteScore
1.00
自引率
0.00%
发文量
75
审稿时长
4-8 weeks
期刊介绍: Chirurgia is a bimonthly journal. In Chirurgia, original papers in the area of general surgery which neither appeared, nor were sent for publication in other periodicals, can be published. You can send original articles, new surgical techniques, or comprehensive general reports on surgical topics, clinical case presentations and, depending on publication space, - reviews of some articles of general interest to surgeons from other publications. Chirurgia is also a place for sharing information about the activity of various branches of the Romanian Society of Surgery, information on Congresses and Symposiums organized by the Romanian Society of Surgery and participation notes in other scientific meetings. Letters to the editor: Letters commenting on papers published in Chirurgia are welcomed. They should contain substantive ideas and commentaries supported by appropriate data, and should not exceed 2 pages. Please submit these letters to the editor through our online system.
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