Harefuah最新文献

{"title":"[Books Review: A Family of Heroes, OUTLIVE, Literature and medicine in German literature between the two world wars].","authors":"Bilha Paryente, Yehuda Shoenfeld, Mordechai Ravid","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Books Review: A Family of Heroes, OUTLIVE, Literature and medicine in German literature between the two world wars.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"734-737"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[THE SURGICAL INTELLIGENCE REVOLUTION - APPLYING AI TO IMPROVE SURGICAL QUALITY AND SAFETY].","authors":"Yuval Mirkin, Dotan Asselman, Sari Maril, Michal Guindy, Tamir Wolf","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The use of artificial intelligence (AI) in medicine is rising fast. We continually hear about novel AI-based technologies being deployed to aid clinical teams in areas like interpreting medical images, understanding pathology, determining diagnosis, predicting prognosis, and deciding on interventions. The field of surgery, however, has been slower to jump on the AI bandwagon. In this paper, we present Surgical Intelligence, an innovative and fast-developing field involving routine capture and AI-based analysis of endoscopic procedure videos. We discuss the need for documenting surgical video, the potential benefits for training and quality improvement, and the features that allow Surgical Intelligence platforms to provide accessible and effective solutions for medical teams.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"687-690"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[EOSINOPHILIC ESOPHAGITIS: MUCH MORE IS UNKNOWN YET THAN DISCOVERED].","authors":"Jawad Hindy, Zahava Vadasz, Tova Rainis","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus, which is mediated by Th2 cells that could start at any age, from early childhood to adulthood. The pathogenesis of the disease is not fully understood, but apparently it consists of a combined interaction between hereditary and environmental factors. Over the years, EoE has become an increasingly diagnosed disease in the context of esophageal symptoms. Nowadays, it is considered the second most common cause of chronic esophagitis and dysphagia (after GERD which is the leading cause on the list). The hallmark of the disease is the presence of eosinophils in the esophageal mucosa (> 15 eosinophil/HPF). Clinically, EoE is characterized by various esophageal symptoms, ranging from mild dysphagia to complications that eventually appear, including esophageal food impaction which usually requires urgent endoscopic removal. Long term complications occur as a result of a defective remodeling process of the inflamed esophagus, which includes histological changes of fibrosis, angiogenesis, and smooth muscle hypertrophy. Due to its progressive course, treatment of the disease requires a close and long-term managerial and therapeutic strategy. There are currently a variety of treatment options for the disease depending on its degree and severity, starting with dietary treatment, pharmacological therapy and ending with esophageal dilations if necessary.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"710-716"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Letters to Editor: The risk for clinically significant copy number variants in pregnancies with two soft markers, Geriatriophobia - a new concept in the medical world in Israel].","authors":"Gustavo Malinger, Amihood Singer, Julia Grinshpun-Cohen, Lena Sagi-Dain, Eliyahu Hayim Mizrahi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Letters to Editor: The risk for clinically significant copy number variants in pregnancies with two soft markers, Geriatriophobia - a new concept in the medical world in Israel.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"738-740"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A 38 YEARS-OLD YOUNG MALE WITH CHEST PAIN AND ECG CHANGES].","authors":"Mohammad Haydar, Roy Bezalel, Uriel Levinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Coronary vasospasm is a well-known condition causing acute chest syndrome and can lead to myocardial infarction, ventricular arrhythmias, and even sudden cardiac death. While there are extensive case series showing the association of coronary vasospasm with drugs like cocaine, the association of marijuana with coronary vasospasm has not been reported frequently. When smoked, marijuana results in a rapid, dose-dependent tachycardia, an increase in blood pressure, and an increase in cardiac output. This in turn leads to increased oxygen demand, which is augmented by the vasoconstriction endothelial damage by smoking and activation of cannabinoid receptor 1 ( CB1) by marijuana. We presented a case of a 38-year-old young male who was admitted with chest pain, ST elevation in electrocardiogram (ECG) and normal coronary arteries at cardiac catheterization and a positive Acetylcholine Provocation test. With the legalization of marijuana and medical cannabis in certain states, marijuana-related hospitalizations and Emergency Room visits are likely to increase. It is therefore important for clinicians to know the various effects of marijuana, especially potentially fatal ones like coronary vasospasm. This case illustrates the importance of recognition of vasospasm in patients taking marijuana .Physicians should consider this in their differential diagnosis of patients presenting with chest pain and history of cannabis use.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"705-708"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[RIGHT HEART FAILURE PRESENTATION OF IDIOPATHIC MASSIVE PULMONARY EMBOLISM - CASE REPORT].","authors":"Doron Menachemi, Margarita Fraimovitch, Roberto Ainbinder, Miriam Judith Ginzburg","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Massive pulmonary embolism (PE) is a life threatening condition with age-related escalation in prevalence. Acute PE is a common and sometimes fatal disease. The approach to the evaluation should be efficient while simultaneously avoiding the risks of unnecessary testing so that therapy can be promptly initiated and potential morbidity and mortality avoided. The imminent condition might lead to obstructive shock with acute right heart failure and eventually to rapid hemodynamic deterioration and death. At a younger age, massive PE causes death very rapidly in one third of the cases. During one year, follow-up of death in the presence of right heart failure is three times higher than those without it. About half of PE cases, are idiopathic and occur without acquired risk factors such as antecedent trauma, surgery, immobilization, or diagnosis of cancer. Unlike provoked PE (pPE) with acquired risk factors, idiopathic PE (iPE) is less likely to be predicted or prevented. Failure to accurately and promptly diagnose and treat deep vein thrombosis (DVT) and PE can result in excess morbidity and mortality due to post thrombotic syndrome, pulmonary hypertension, and recurrent thrombosis. Chest pain and shortness of breath are chief complaints frequently evaluated in the emergency department. Younger patients tend to have benign presentations, and often leave with diagnoses of self-limiting diseases or etiologies that are easily treated in the emergency department. The presenting clinical signs and symptoms should illuminate the primary physician to this life-threatening condition leading to fast diagnosis and prompt lifesaving treatment. At the end of the primary treatment, we need to assess and address each patient for the likelihood of thromboembolism recurrence, which will be highest among those patients with idiopathic events or those with cancer-associated thrombosis. We favor prolonged anticoagulation in these scenarios. In addition, we strongly advocate periodic scheduled follow-up of patients on long-term anticoagulation for secondary prophylaxis to re-evaluate their bleeding and recurrence risk. In practice, initial treatment of deep venous thrombosis and pulmonary embolism should be based on low molecular weight heparin (LMWH) in patients without renal failure. Thrombolytic agents may be useful in case of massive pulmonary embolism, but more evaluation is needed. Bleeding and heparin thrombocytopenia are the main adverse effects of these treatments.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"695-698"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[EFFECTIVENESS OF SERIAL C-REACTIVE PROTEIN (CRP) MEASUREMENTS IN HOSPITALIZED PATIENTS WITH BLOOD STREAM INFECTION].","authors":"Yuval Schwartz, Aviv Hanuka, Tali Bdolah-Abram, Marc V Assous, Amos M Yinnon, Gavriel Munter","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>C-reactive protein (CRP) is increasingly being used as an inflammatory marker in sepsis. Its main use is for diagnosis, less for prognosis, while it is increasingly used for serial monitoring of response to treatment - with little evidence to support this practice.</p><p><strong>Objectives: </strong>Assessment of the effectiveness of serial measurements of CRP in the management of patients with blood stream infection (BSI).</p><p><strong>Methods: </strong>This was a retrospective study of two patient cohorts, one in 2015 (cohort A) and the other in 2018 (cohort B), each included 200 consecutively diagnosed patients with proven BSI. We assessed the following outcome markers: antibiotic management, duration of admission and in-hospital mortality.</p><p><strong>Results: </strong>Baseline demographic and clinical data of the cohorts were similar. In cohort A, a single CRP test was obtained from 5% of the patients, while in cohort B, 95% of patients had CRP tests with a mean of 5.7 tests/person. Empiric, appropriate antibiotic treatment, increased from 72% in cohort A to 75% in cohort B (NS). Duration of antibiotic treatment did not change (10±8 days). The in-hospital mortality rate decreased from 38.5% in cohort A to 30.5% in cohort B (NS), as did mortality <7 days after diagnosis of BSI, from 17.5% to 14% respectively (NS).</p><p><strong>Conclusions: </strong>We found statistically insignificant differences between the cohorts. In our view there is currently no solid evidence to support the serial use of CRP tests in the management of patients with BSI.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"699-704"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Does the Term \"Myocardial Infarction\" Represent its Meaning Properly?]","authors":"Ronen Spierer, Moshe Y Flugelman","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Does the Term \"Myocardial Infarction\" Represent its Meaning Properly?</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"732-733"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[TREATMENT UPDATES IN OCULAR ONCOLOGY].","authors":"Hashem Totah, Ehud Raich","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Malignant tumors of the eye are uncommon, yet of great importance due to their effect on the patient's life and vision. The most common primary intraocular tumors are retinoblastoma in children and uveal melanoma in adults. The most common periocular tumor is basal cell carcinoma in eyelids. Management of these tumors can be challenging. On one hand, it can be difficult to control intraocular tumors like retinoblastoma or uveal melanoma from spreading out of the eye which will decrease the chances of survival of these patients. On the other hand, in eyelid tumors that have spread into the ocular tissue, this can make it surgically non-removable. In the past decades, many new treatments, local and systemic, have emerged with the main aim of saving the patient's life, as well as saving the globe of the eye and when possible, the vision. This has improved the overall survival of these patients. In this article, we reviewed the latest advances in the treatment of these tumors in the past decade. In addition, we reviewed the advances in the management and treatment of conjunctival melanoma, a very rare but lethal malignant tumor of the eye.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"717-722"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[CAN NATURAL SKIN CREASE PREDICT OUR PHALANX JOINT ALIGNMENT?]","authors":"Dana Avraham, Maria Oulianski, Amir Herman, Yona Kosashvili, Amir Oron, Arie L Greenberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Proximal interphalangeal injury may result in malalignment of the phalanx axis of motion. In some instances, these fractures are treated with an external fixation method such as Suzuki-type fixation, during which the surgeon must perform X-rays to preserve the phalanx anatomical axis of motion.</p><p><strong>Objectives: </strong>To assess the correlation between the palmar skin crease and the joint axis of the proximal interphalangeal joint (PIPJ) of the fingers opposing the thumb to improve the surgeons' perioperative planning procedure. Also, we aim to ascertain whether sex, age, and handedness have affected our findings.</p><p><strong>Methods: </strong>We performed a single-center prospective study in which information on 144 digits from 18 patients was gathered. Radiopaque stainless-steel wire was used to mark the palmar skin crease of the PIPJ and a series of X-rays were performed to assess the actual axis of the PIPJ correlating to the marked skin crease.</p><p><strong>Results: </strong>Our study shows a positive correlation between Cobb angle finger 2 and 5 (r = .468, p < .05). Also, a positive correlation between Cobb angle finger 3 and finger 4 (r = .474, p < .05). No significant differences were found between age groups, and right and left hands. Finger 2 Cobb angle was significantly higher in females (F = 2.27, M = 1.49), p = .048.</p><p><strong>Conclusions: </strong>The study results support the hypothesis that the palmar proximal interphalangeal skin crease is positively correlated with the joint line axis measurement from which the axis of motion is formed. Our findings show homogeneity across age and hand-sidedness.</p>","PeriodicalId":101459,"journal":{"name":"Harefuah","volume":"163 11","pages":"691-694"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}