[一例伴有中度葡萄膜炎的多发性硬化新诊断]。

Harefuah Pub Date : 2025-03-01
Tom Kozlovsky, Idit Maharshak, Asaf Bar
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引用次数: 0

摘要

葡萄膜炎是一组约30种眼内炎性疾病;多发性硬化症(MS)是一种免疫介导的中枢神经系统慢性炎症性疾病。据报道,中度葡萄膜炎是与MS相关的最常见的葡萄膜炎类型。MS与葡萄膜炎相关的机制尚不清楚,但先前的数据表明遗传易感性可能起作用。此外,在神经系统症状发作前出现葡萄膜炎的多发性硬化症患者往往表现为病情较轻,进展缓慢。这一观察结果可能归因于早期给予这些患者治疗葡萄膜炎的免疫调节治疗。我们描述了一位女性患者,她被诊断为中度葡萄膜炎,定义为未分化;9年后,她被诊断出患有复发缓解型多发性硬化症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[A NEW MULTIPLE SCLEROSIS DIAGNOSIS IN A PATIENT WITH INTERMEDIATE UVEITIS].

Introduction: Uveitis is a group of about 30 intra-ocular inflammatory diseases; multiple sclerosis (MS) is an immune-mediated chronic inflammatory disease of the central nervous system (CNS). Intermediate uveitis has been reported to be the most common type of uveitis in association with MS. The mechanism associating MS and uveitis is not clear, but previous data suggest a genetic predisposition may play a role. In addition, MS patients presenting with uveitis prior to the onset of neurological symptoms tend to demonstrate a milder form of the disease with moderate progression. This observation may be attributed to early immunomodulatory treatment given to those patients to treat uveitis. We describe a female patient who was diagnosed with intermediate uveitis that was defined as undifferentiated; 9 years later, she was diagnosed with relapsing-remitting MS.

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