Revista medica de Chile最新文献_第2页

[Neurocognitive Performance in Patients with End-Stage Chronic Kidney Disease: Differences Between Conservative Medical Management and Hemodialysis].

Revista medica de Chile Pub Date : 2024-11-01 DOI: 10.4067/s0034-98872024000800856

Luna Sánchez, Bárbara Lanis, Nicolás Meza, Gustav Rohde

{"title":"[Neurocognitive Performance in Patients with End-Stage Chronic Kidney Disease: Differences Between Conservative Medical Management and Hemodialysis].","authors":"Luna Sánchez, Bárbara Lanis, Nicolás Meza, Gustav Rohde","doi":"10.4067/s0034-98872024000800856","DOIUrl":"https://doi.org/10.4067/s0034-98872024000800856","url":null,"abstract":"No consensus has been reached about how cognitive performance evolves in patients receiving hemodialysis (HD).Aim: to analyze the cognitive performance of patients with end-stage chronic kidney disease (CKD) undergoing conservative medical management or HD.Methods: We conducted a cross-sectional study. The cognitive performance of both groups was assessed through the INECO Frontal Screening (IFS) instrument.Results: 6 patients were analyzed in each group (n= 12). A significant difference was observed for the total IFS score, with 14.4±6.29 points in the HD group and 21.5±3.96 points in the conservative management group (p<0.05). Regarding the specific domains of the IFS, a significant difference was found in the domain of verbal inhibitory control, with an average of 1.83±1.17 points in the HD group and 4±0.89 points in the conservative management group (p<0.05). No associations were elucidated on the abbreviated MMSE, ACE-III, TMT-A and B, Grober and Buschke Test, Stroop Test and Boston Test Nomination Test.Conclusion: Patients with terminal CKD on HD (even those with a normal MMSE result) show an impairment in their executive functions compared to those who underwent conservative management.","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":"152 8","pages":"856-866"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Breast Cancer in Male Patients of the Aconcagua Valley During the Period 2013-2018].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000900978

Camila Vera Montenegro, Natalia Pérez Barraza, Juan Collantes, Manuela Tello, Camila Riveros

{"title":"[Breast Cancer in Male Patients of the Aconcagua Valley During the Period 2013-2018].","authors":"Camila Vera Montenegro, Natalia Pérez Barraza, Juan Collantes, Manuela Tello, Camila Riveros","doi":"10.4067/s0034-98872024000900978","DOIUrl":"https://doi.org/10.4067/s0034-98872024000900978","url":null,"abstract":"Breast cancer in men is a rare disease, accounting for around 1% of all cancers in males. Diagnosis often occurs in advanced stages due to low awareness of this disease in males.Aim: To evaluate the clinical, epidemiological, and histopathological characteristics of breast cancer in men in the Aconcagua Valley and its relationship with patient survival.Methods: A descriptive study was conducted at the University of Valparaíso, analyzing data from seven male patients diagnosed with breast cancer at San Camilo Hospital in San Felipe between 2013 and 2018. Epidemiological, clinical, and histopathological data were analyzed using statistical software.Results: The average age of surviving men was higher compared to those who died. However, no statistically significant association was found between clinical and histopathological variables and patient survival.Conclusions: Despite the limited sample size, the results suggest that factors such as age and clinical and histopathological variables are not significantly associated with survival in men with breast cancer. These findings highlight the need for further research with larger sample sizes to better understand this population's survival factors.","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":"152 9","pages":"978-986"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Survival in Patients with Acute Myeloid Leukemia: A Survival Analysis of 120 Patients with Acute Myeloid Leukemia with a Focus on Patients Over 60 Years of Age at Sótero del Río Hospital].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000900939

Ignacio Domínguez, Rodrigo Naser, Marcelo Abarca

{"title":"[Survival in Patients with Acute Myeloid Leukemia: A Survival Analysis of 120 Patients with Acute Myeloid Leukemia with a Focus on Patients Over 60 Years of Age at Sótero del Río Hospital].","authors":"Ignacio Domínguez, Rodrigo Naser, Marcelo Abarca","doi":"10.4067/s0034-98872024000900939","DOIUrl":"https://doi.org/10.4067/s0034-98872024000900939","url":null,"abstract":"Acute myeloid leukemia (AML) is the most frequent type of leukemia in adults and has a high mortality burden. Patients over 60 years of age infrequently receive high-intensity chemotherapy.Aim: To describe the clinical characteristics and evaluate the survival in patients with AML, focusing on patients over 60 years.Methods: A retrospective study of patients diagnosed and treated for non-promyelocytic AML at Sótero del Río Hospital in Santiago, Chile, between 2015 and 2022.Results: 120 patients with a median age at presentation of 57 years were included. 56% were male-overall survival was 19% at 3 years. The group treated with high-intensity chemotherapy had a survival chance of 35% at 3 years. Sixty-five patients were 60 years or older, of whom 15 received high-intensity chemotherapy with 20% survival at 3 years, which was significantly higher than the non-chemotherapy group, i.e., palliative care (46% vs. 5.2% at 1 year, p-value <0.001).Conclusion: Results with chemotherapy in patients 60 years of age and above are good, but the proportion of patients treated in the age group was low compared to other national reports.","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":"152 9","pages":"939-947"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Health Literacy and Metabolic Control in Individuals Diagnosed with Type 2 Diabetes Mellitus: A Cluster Randomized Clinical Trial].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000900969

Claudia Bustamante-Troncoso, Claudia Alcayaga-Rojas, Hugo Sánchez Reyes, J Carola Pérez Ewert, Giselle Riquelme Hernández, Miriam Rubio Acuña, Solange Campos-Romero, Milagros C Rosal

{"title":"[Health Literacy and Metabolic Control in Individuals Diagnosed with Type 2 Diabetes Mellitus: A Cluster Randomized Clinical Trial].","authors":"Claudia Bustamante-Troncoso, Claudia Alcayaga-Rojas, Hugo Sánchez Reyes, J Carola Pérez Ewert, Giselle Riquelme Hernández, Miriam Rubio Acuña, Solange Campos-Romero, Milagros C Rosal","doi":"10.4067/s0034-98872024000900969","DOIUrl":"https://doi.org/10.4067/s0034-98872024000900969","url":null,"abstract":"People with type 2 diabetes mellitus (DM2) experience difficulties in self-management. One of the variables involved is the low level of health literacy (HL) which corresponds to the degree to which people access, understand, evaluate and use information to engage with health demands in different contexts, in order to promote and maintain good health.Hypothesis: People diagnosed with diabetes mellitus who participate in an intervention to increase their level of health literacy improve their metabolic compensation measured in HBA1c.Aim: To evaluate the effect of an HL intervention program on metabolic control and self-efficacy of people with DM2, who are treated in primary care centers (CESFAM) in a commune in Santiago, Chile.Methods: A randomized controlled clinical trial in a cluster, in 4 CESFAM, 2 intervention group (IG) and 2 control group (CG). In addition to the usual intervention, the CESFAM-GI received face-to-face and telephone follow-up counseling, group sessions, and audiovisual support material for a period of 6 months. Pre- and post-intervention measurements were taken.Results: No differences were observed in the HbA1C values of the GI between baseline and final measurements; however, in the CG it increased by 1 point between both measurements, showing a deterioration compared to the IG. Attendance at the workshops in the IG is positively associated with the achievement of LS level. The results indicate that the intervention was more effective -than the usual intervention- in preventing the deterioration of HbA1C.Conclusions: An intervention that considers LS adapted to the Latin American sociocultural context with a combination of group and individual strategies can generate a difference in HBA1c.","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":"152 9","pages":"969-977"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Amphotericin B Liposomal Lock Therapy in Fungal Peritonitis in a Patient With Peritoneal Dialysis: Regarding a Challenging Case].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000901017

Eduardo Ávila, Lucy Abarzúa, Belén Gallardo, Waldo Gutiérrez, Mireya Ortiz

引用次数: 0

[Migration of Elderly People: A New Scenario for Our Practice in Health and Rehabilitation].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000901026

Jorge Ugarte Llanten

引用次数: 0

[Utility of CT Cardiac Angiography in the Evaluation of Infective Endocarditis and Its Complications].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000901008

Cristóbal Reyes, Daniel Schneider, Marcelo Godoy

引用次数: 0

Hypophosphatemic Rickets as a Key Sign for the Diagnosis of Hereditary Tyrosinemia Type 1: Case Reports and Narrative Review of the Literature.

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000900997

Andrés de Tezanos-Pinto D, Marcela Godoy P, Carolina Arias P, Patricio Romero M, Juan F Cabello A, Maritza Vivanco J

{"title":"Hypophosphatemic Rickets as a Key Sign for the Diagnosis of Hereditary Tyrosinemia Type 1: Case Reports and Narrative Review of the Literature.","authors":"Andrés de Tezanos-Pinto D, Marcela Godoy P, Carolina Arias P, Patricio Romero M, Juan F Cabello A, Maritza Vivanco J","doi":"10.4067/s0034-98872024000900997","DOIUrl":"https://doi.org/10.4067/s0034-98872024000900997","url":null,"abstract":"Hereditary tyrosinemia type 1 (HT-1) is an inborn error of metabolism caused by a defect in tyrosine (tyr) degradation. This defect results in the accumulation of succinylacetone (SA), causing liver failure with a high risk of hepatocarcinoma and kidney injury, leading in turn to Fanconi syndrome with urine loss of phosphate and secondary hypophosphatemic rickets (HR). HT-1 diagnosis is usually made in infants with acute or chronic liver failure or by neonatal screening programs. HR is rarely described in the literature as the main feature or chief complaint of patients with HT-1. Clinical cases: We present three children who presented signs of HR during infancy. Patient 1 had early liver dysfunction, leading to a quick diagnosis of HT-1. Patients 2 and 3 started conventional therapy for HR (calcitriol and oral phosphate) with partial clinical response. Later, both developed liver dysfunction, and patient 3 presented neurological symptoms (porphyria-like crises). An HT-1 diagnosis was made using tandem mass spectrometry, which confirmed high plasma levels of SA and tyr. After diagnosis, all started treatment with a specific diet and nitisinone with prompt recovery and a quick remission of clinical signs of HR, being able to discontinue their conventional rickets therapy successfully. Conclusion: We present three patients with HT-1 whose main complaint was HR. It is important to know the main features of this metabolic disorder and have a high index of suspicion when we follow-up children with HR, especially if they are not responding to conventional therapy or develop liver dysfunction.","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":"152 9","pages":"997-1007"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hematopoietic Transplantation Outcomes in Patients with HLA-Identical, Haploidentical, and Unrelated Donors at a University Hospital in Chile].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000900960

Mauricio Sarmiento, Javier Díaz, Patricio Rojas, Catherine Gutiérrez, Verónica Jara, Marcela Vidal, James Campbell, María José García, Yorman Flores, Vicente Sandoval, Felipe Palacios, Maximiliano Vergara, Mauricio Ocqueteau, Francisco Barriga

{"title":"[Hematopoietic Transplantation Outcomes in Patients with HLA-Identical, Haploidentical, and Unrelated Donors at a University Hospital in Chile].","authors":"Mauricio Sarmiento, Javier Díaz, Patricio Rojas, Catherine Gutiérrez, Verónica Jara, Marcela Vidal, James Campbell, María José García, Yorman Flores, Vicente Sandoval, Felipe Palacios, Maximiliano Vergara, Mauricio Ocqueteau, Francisco Barriga","doi":"10.4067/s0034-98872024000900960","DOIUrl":"https://doi.org/10.4067/s0034-98872024000900960","url":null,"abstract":"Allogeneic transplantation (HSCT) is a curative option for several hematological diseases. Our center has privileged the use of identical family donors (IFD) or haploidentical (HD) donors. However, the chances of finding family donors may be challenging in small families or unsuitable donors. In these cases, there is the possibility of obtaining hematopoietic precursors from unrelated donors (URD) with complete or almost complete HLA compatibility.Aim: this work analyzes the results of a historical cohort of patients with allogeneic transplantation in our institution.Methods: a retrospective analysis of data base and clinical records of patients with allogeneic transplantation in our adult transplantation program.Results: between 2005 and 2023, 370 TPH were performed, of which 150 were IFD (40%), 167 HD (45%) and 53 URD (15%). The median age of the patients was 37 years (range 16-76), the majority were transplanted for acute leukemia (60%) and 41% were women. With a median follow-up of 8 years, the overall survival was 64, 67, and 65% for IFD, HD or URD. Subgroup analysis showed more severe cases of graft versus host disease in HD group (p= 0.001).Conclusion: our experience shows that the results of DNR, DFI, and DFH are similar. 15% of patients were transplanted with URD because of the absence of suitable family donors.","PeriodicalId":101370,"journal":{"name":"Revista medica de Chile","volume":"152 9","pages":"960-968"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[β-Lactam Hypersensitivity: Narrative Review and an Inpatient Management Algorithm Proposal].

Revista medica de Chile Pub Date : 2024-09-01 DOI: 10.4067/s0034-98872024000900987

Patricio Ross, Tomás Reyes-Barros, María Teresa Peralta, Luis Rojas, Raquel Aguilera-Insuza

引用次数: 0