Anesthesia and pain medicine最新文献_第6页

General anesthesia without neuromuscular blocking agents using regional blocks in rocuronium-induced anaphylaxis - A case report. 全麻无神经肌肉阻滞剂，局部阻滞治疗罗库溴铵致过敏反应1例报告。

IF 3.6

Anesthesia and pain medicine Pub Date : 2026-04-01 Epub Date: 2026-03-11 DOI: 10.17085/apm.25396

Ji Young Kim, Young Chul Yoo, Na Young Kim, Hyeon Woo Bae, Soo Jung Park

{"title":"General anesthesia without neuromuscular blocking agents using regional blocks in rocuronium-induced anaphylaxis - A case report.","authors":"Ji Young Kim, Young Chul Yoo, Na Young Kim, Hyeon Woo Bae, Soo Jung Park","doi":"10.17085/apm.25396","DOIUrl":"10.17085/apm.25396","url":null,"abstract":"Background: Neuromuscular blocking agents (NMBAs) are the leading cause of perioperative anaphylaxis. In confirmed cases with limited non-cross-reactive options, safe anesthesia requires coordination and muscle relaxant-free strategies.Case: A 64-year-old woman with confirmed rocuronium-induced anaphylaxis and multiple comorbidities-including poorly controlled diabetes, coronary artery disease, chronic obstructive pulmonary disease, and obesity-underwent laparoscopic anterior resection of the sigmoid colon. General anesthesia was induced and maintained without muscle relaxants using total intravenous anesthesia and regional blocks. Airway topicalization and deep anesthesia enabled smooth intubation. Bilateral transversus abdominis plane and rectus sheath blocks provided effective somatic analgesia and abdominal relaxation. Ventilation and hemodynamic parameters remained stable throughout. The patient recovered uneventfully, without agitation or delayed arousal, and was discharged uneventfully on postoperative day 5.Conclusions: This report describes the feasibility of NMBA-free general anesthesia using intravenous agents and targeted regional blocks in high-risk patients with confirmed anaphylaxis, even in laparoscopic procedures.","PeriodicalId":101360,"journal":{"name":"Anesthesia and pain medicine","volume":"21 2","pages":"252-257"},"PeriodicalIF":3.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147944586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A scoping review approach for synthesizing and mapping research in anesthesia and pain medicine. 麻醉与疼痛药物合成与图谱研究的范围综述方法。

IF 3.6

Anesthesia and pain medicine Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.17085/apm.25402

Hyun-Ju Seo

引用次数: 0

Comment on "Anesthetic management of a 9-year-old girl with Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay syndrome: airway difficulties and postoperative apnea during tendon surgery". 评论“一名患有先天性四肢和面部挛缩、低张力和发育迟缓综合征的9岁女孩的麻醉处理：肌腱手术期间气道困难和术后呼吸暂停”。

IF 3.6

Anesthesia and pain medicine Pub Date : 2026-04-01 Epub Date: 2026-01-23 DOI: 10.17085/apm.25390

Reena, Amrita Rath

引用次数: 0

Comparison of the recovery profiles of remimazolam-remifentanil and propofol-remifentanil in older patients undergoing laparoscopic abdominal surgeries. 雷马唑仑-瑞芬太尼与异丙酚-瑞芬太尼在老年腹腔镜腹部手术患者恢复情况的比较。

IF 3.6

Anesthesia and pain medicine Pub Date : 2026-04-01 Epub Date: 2026-04-29 DOI: 10.17085/apm.24154

Seung Cheol Lee, Chan Jong Chung, Seok Hyun Ma, So Ron Choi, Sang Yoong Park, Tae Young Lee

{"title":"Comparison of the recovery profiles of remimazolam-remifentanil and propofol-remifentanil in older patients undergoing laparoscopic abdominal surgeries.","authors":"Seung Cheol Lee, Chan Jong Chung, Seok Hyun Ma, So Ron Choi, Sang Yoong Park, Tae Young Lee","doi":"10.17085/apm.24154","DOIUrl":"10.17085/apm.24154","url":null,"abstract":"Background: We compared the quality of recovery (QoR) between total intravenous anesthesia using remimazolam and propofol in older patients undergoing laparoscopic abdominal surgeries.Methods: A total of 120 patients (aged ≥ 60 years) undergoing laparoscopic gastric or colorectal surgery were randomized to the remimazolam or propofol group. Continuous remimazolam/propofol infusion and target-controlled remifentanil infusion were performed. Recovery was evaluated using the Korean version of the Quality of Recovery-15 (QoR-15K) questionnaire. The primary outcome was the QoR-15K score on postoperative day (POD) 3. Secondary outcomes included the QoR-15K score on POD 1; perioperative mean arterial pressure and heart rate; times to eye opening, extubation, and full recovery; post-anesthetic care unit (PACU) adverse events; postoperative delirium; and duration of hospitalization.Results: The total QoR-15K scores over time did not make differences significantly between the groups. Total QoR-15K scores on POD 3 (112.0 [96.0, 119.0] vs. 104.0 [84.8, 120.5], P = 0.481) and POD 1 (80.0 [62.0, 97.0] vs. 78.0 [60.8, 95.3], P = 0.635) were comparable between the groups. The MAP and HR were significantly higher in the remimazolam group. The times to extubation (12.0 [11.0, 15.0] vs. 10.5 [9.0, 12.3] min, P = 0.003) and full recovery (13.0 [9.0, 16.0] vs. 11.5 [8.0, 14.0] min, P = 0.045) were notably longer in the remimazolam group. The incidence of adverse events in the PACU and postoperative delirium, and duration of hospitalization were comparable between the groups.Conclusions: Remimazolam yielded a similar QoR as propofol in older patients undergoing laparoscopic abdominal surgeries.","PeriodicalId":101360,"journal":{"name":"Anesthesia and pain medicine","volume":"21 2","pages":"212-222"},"PeriodicalIF":3.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147944571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of milrinone-terlipressin infusion on blood loss and portal pressure during hepatic resection: a randomized controlled trial. 米立酮-特利加压素输注对肝切除术中出血量和门静脉压力的影响：一项随机对照试验。

IF 3.6

Anesthesia and pain medicine Pub Date : 2026-04-01 Epub Date: 2026-03-11 DOI: 10.17085/apm.25301

Vanni Subhash Jhawar, Ashish Singh Aditya, Tanvir Samra, Harjeet Singh, Vikas Saini

{"title":"Effect of milrinone-terlipressin infusion on blood loss and portal pressure during hepatic resection: a randomized controlled trial.","authors":"Vanni Subhash Jhawar, Ashish Singh Aditya, Tanvir Samra, Harjeet Singh, Vikas Saini","doi":"10.17085/apm.25301","DOIUrl":"10.17085/apm.25301","url":null,"abstract":"Background: Low central venous pressure (CVP) and Pringle maneuver are commonly employed strategies to reduce bleeding during hepatic resection. Milrinone and terlipressin lower hepatic venous pressure and portal venous pressure (PVP), thereby reducing the risk of bleeding. This study compared the intraoperative blood loss between a combined infusion of milrinone and terlipressin, and terlipressin alone in patients undergoing elective hepatic resection.Methods: A total of 36 patients were randomized to the Milrinone and terlipressin or Terlipressin groups, who received infusions starting 30 min before the beginning of liver resection until the end of the surgery. The primary objective was to determine differences in blood loss between the two groups.Results: Thirty-four patients (17 in each group) were assessed by stratification into major and minor hepatic resections. The median (1Q, 3Q) intraoperative blood loss (in ml) was lower in Milrinone and terlipressin group than in Terlipressin group (570 [329, 880] vs. 824 [750, 1,146]; P = 0.046). In minor resections, milrinone and terlipressin had lower blood loss than terlipressin (373 [273, 556] vs. 798 [725, 1,230]; P = 0.015). There is no difference between the two groups in blood loss during major hepatic resection. The decreases in PVP and CVP at 30 min post-infusion were significant in the Milrinone and terlipressin group (P = 0.002 and P = 0.027, respectively).Conclusions: The combination of milrinone and terlipressin significantly reduces intraoperative blood loss, especially during minor hepatic resections.","PeriodicalId":101360,"journal":{"name":"Anesthesia and pain medicine","volume":"21 2","pages":"203-211"},"PeriodicalIF":3.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13175905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147944553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to: Comment on "Clinical roles of point-of-care ultrasonography in airway management". 回复：关于“现场超声检查在气道管理中的临床作用”的评论。

IF 3.2

Anesthesia and pain medicine Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.17085/apm.25514

Hyungseok Seo, Chung-Sik Oh, Geun Joo Choi, Jung-Bin Park

引用次数: 0

Frailty assessment in perioperative geriatric patients: a narrative review. 围手术期老年患者的衰弱评估：叙述性回顾。

IF 3.2

Anesthesia and pain medicine Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.17085/apm.25480

Tae-Yun Sung, Chung-Sik Oh

{"title":"Frailty assessment in perioperative geriatric patients: a narrative review.","authors":"Tae-Yun Sung, Chung-Sik Oh","doi":"10.17085/apm.25480","DOIUrl":"10.17085/apm.25480","url":null,"abstract":"Frailty is increasingly recognized as a major determinant of perioperative risk in the geriatric population. It is characterized by reduced physiological reserve and impaired stress tolerance and arises from multisystem dysregulation involving chronic inflammation, neuroendocrine changes, sarcopenia, and organ dysfunction. Unlike chronological aging, frailty reflects biological vulnerability independent of comorbidity or disability and is strongly associated with postoperative complications, prolonged hospitalization, cognitive decline, and mortality. Therefore, early and systematic frailty assessment is essential to optimize perioperative management, support clinical decision-making, and implement tailored interventions. Multiple validated frailty assessment strategies exist, ranging from phenotypic models such as the Fried Frailty Phenotype to deficit accumulation tools such as the Frailty Index (FI). Practical bedside instruments, including the Clinical Frailty Scale, Edmonton Frail Scale, fatigue, resistance, ambulation, illnesses, loss of weight (FRAIL) questionnaire, modified FI, and disease-specific screening tools, enable rapid detection in clinical settings. Frailty assessment should be performed early and efficiently to facilitate targeted prehabilitation, nutritional optimization, and cognitive support, all of which have been associated with improved functional outcomes. It also informs individualized anesthetic strategies, including drug titration, hemodynamic stabilization, lung-protective ventilation, and delirium prevention. However, barriers to implementation-such as limited clinician awareness, time constraints, and lack of standardized protocols-continue to hinder routine use. Future integration may be accelerated by artificial intelligence, telemedicine, and digital monitoring technologies to enhance geriatric anesthesia. This review provides a comprehensive overview of frailty in geriatric patients, highlighting its definition, pathophysiology, assessment methods, and clinical impact.","PeriodicalId":101360,"journal":{"name":"Anesthesia and pain medicine","volume":"21 1","pages":"51-66"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraoperative lactate level and lactate clearance is associated with long-term mortality in liver transplant recipients. 肝移植受者术中乳酸水平和乳酸清除率与长期死亡率相关。

IF 3.2

Anesthesia and pain medicine Pub Date : 2026-01-01 Epub Date: 2025-11-17 DOI: 10.17085/apm.25331

Akira Katayama, Ezeldeen Abuelkasem, Marianne M Ligon, Yaroslava Longhitano, David W Wang

{"title":"Intraoperative lactate level and lactate clearance is associated with long-term mortality in liver transplant recipients.","authors":"Akira Katayama, Ezeldeen Abuelkasem, Marianne M Ligon, Yaroslava Longhitano, David W Wang","doi":"10.17085/apm.25331","DOIUrl":"10.17085/apm.25331","url":null,"abstract":"Background: Hyperlactatemia has been associated with poor outcomes in various clinical settings including liver transplantation (LT). However, the impact of intraoperative lactate levels and lactate clearance on long-term mortality in LT recipients remains unclear.Methods: We retrospectively reviewed data from 1,067 patients who underwent LT. All lactate data measured intraoperatively were used to calculate the time-weighted average lactate (TWAL) method. Lactate clearance was calculated as the difference between lactate levels immediately after reperfusion and at the end of surgery. Multivariable analyses were performed to identify independent predictors of mortality after LT.Results: Higher lactate group showed significantly worse survival at 30-days, 1-year, and 3-years (P = 0.01, P < 0.001, and P < 0.001, respectively), and lactate clearance was significantly lower in non-survivors (P = 0.003, P = 0.003, and P = 0.002, respectively). Multivariable analyses revealed that the TWAL was independently associated with each mortality timepoint (hazard ratio [HR], 1.41, 95% confidence interval [CI], 1.19-1.67; P < 0.001, HR, 1.29, 95% CI, 1.17-1.42; P < 0.001, HR, 1.20, 95% CI, 1.10-1.30; and P < 0.001, respectively). Furthermore, lactate clearance was also an independent predictor for each mortality timepoint (HR, 0.69, 95% CI, 0.60-0.80; P < 0.001, HR, 0.80, 95% CI, 0.73-0.88; P < 0.001, and HR, 0.83, 95% CI, 0.77-0.90; P < 0.001, respectively).Conclusions: Both intraoperative lactate level and lactate clearance were independently associated with mortality after LT. Intraoperative lactate monitoring may help predict both short- and long-term mortality in LT recipients.","PeriodicalId":101360,"journal":{"name":"Anesthesia and pain medicine","volume":"21 1","pages":"72-82"},"PeriodicalIF":3.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to: Pathway from anterior suprascapular nerve block to the phrenic nerve: a cadaveric dye study. 从肩胛前上神经阻滞到膈神经的通路：尸体染色研究。

IF 3.2

Anesthesia and pain medicine Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.17085/apm.24142.e1

Sandeep Diwan, Deepika Sathe, Anjali Sabnis, Prakash Mane, Anju Gupta

引用次数: 0

A message from the Editor-in-Chief and Editorial Board, 2025: journal metrics and statistics, and appreciation to reviewers. 总编辑和编辑委员会的信息，2025：期刊指标和统计，以及对审稿人的感谢。

IF 3.2

Anesthesia and pain medicine Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.17085/apm.26515

Jun Hyun Kim, Hyun Kang

引用次数: 0