Korean journal of ophthalmology : KJO最新文献

{"title":"Vitreous Opacity Following Intravitreal Brolucizumab Injection: A Case Series Review.","authors":"Kook Hyung Lee, Sung Chul Lee, Min Woo Lee","doi":"10.3341/kjo.2023.0133","DOIUrl":"10.3341/kjo.2023.0133","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate cases of vitreous opacity (VO) similar to asteroid hyalosis (AH) after intravitreal brolucizumab injection.</p><p><strong>Methods: </strong>A retrospective chart review was conducted to identify cases showing VO similar to AH among patients who received intravitreal brolucizumab injections at our retinal clinic from January 2022 to January 2023.</p><p><strong>Results: </strong>A total of 220 brolucizumab injections were administered at our hospital. VO, showing yellow-white brilliant reflective particles, was found in six patients (2.7%). When VO occurred, all patients complained of floaters, although none of them complained of other symptoms including decreased visual acuity, pain, or conjunctival redness. The mean number of brolucizumab injections was 2.57 ± 2.38. No significant visual impairment was observed while VO was present. VO improved in all cases, and four cases improved without any treatment. The mean interval from onset to disappearance of VO was 8.0 ± 3.1 weeks.</p><p><strong>Conclusions: </strong>VO, similar to AH, can occur with a relatively high probability after intravitreal brolucizumab injections. Patients complained of severe floaters, but VO was not accompanied by other symptoms including vision impairment, injection, and pain. The VO disappeared after approximately 4 to 14 weeks. In case that other inflammatory findings are not severe, close follow-up without treatment may be sufficient. If a patient complains of floaters after an intravitreal brolucizumab injection, close fundus observation is necessary to evaluate the VO.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"113-121"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-year Outcomes of Ultrathin Descemet Stripping Automated Endothelial Keratoplasty Combined with Cataract Surgery in the Korean Population.","authors":"Minjeong Ashley Koo, Hye Yeon Yoon, Jae Hyun Park, So-Hyang Chung, Hyun-Seung Kim, Yong-Soo Byun","doi":"10.3341/kjo.2023.0101","DOIUrl":"10.3341/kjo.2023.0101","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the refractive outcomes after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) combined with phacoemulsification and intraocular lens implantation (triple procedure) in the South Korean population.</p><p><strong>Methods: </strong>This retrospective observational study included 37 eyes of 36 patients who underwent the UT-DSAEK triple procedure between 2012 and 2021 in a single tertiary hospital. Preoperative and postoperative refractive outcomes and endothelial parameters at 1, 3, 6, and 12 months were observed.</p><p><strong>Results: </strong>At the final postoperative 12-month period, the average best-corrected visual acuity was 0.4 ± 0.5 in logarithm of the minimum angle of resolution. The mean endothelial cell density at 12 months was 1,841.92 ± 731.24 cells/mm2, indicating no significant endothelial cell loss compared to the baseline (p = 0.128). The mean postoperative central corneal thickness at 12 months was 597.41 ± 86.26 μm. The postoperative mean absolute error at 12 months was 0.96 ± 0.89 diopters (D) and mean error was 0.89 ± 0.97 D.</p><p><strong>Conclusions: </strong>The results of our South Korean cohort study on UT-DSAEK triple surgery showed favorable and safe outcomes. Regardless of graft thickness, it should be noted that a hyperopic shift of 1.00 to 2.00 D needs to be considered in the case of UT-DSAEK triple surgery.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"105-112"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Phenotypic Presentation of RPGR-associated X-linked Retinitis Pigmentosa in Female Carriers: Two Case Reports.","authors":"Hansol Park, Sungsoon Hwang, Sang Jin Kim","doi":"10.3341/kjo.2023.0119","DOIUrl":"10.3341/kjo.2023.0119","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"164-166"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uveitis with Hyphema Mimicking Infectious Endophthalmitis after Glaucoma Filtering Surgery: A Case Report.","authors":"Jaeheon Kim, Ki Tae Nam, Hye Jin Lee, Jinho Jeong, Ahnul Ha","doi":"10.3341/kjo.2023.0132","DOIUrl":"10.3341/kjo.2023.0132","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"176-177"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Treatment of Orbital Lymphatic Malformation Using Foam Sclerotherapy with 3% Sodium Tetradecyl Sulfate: A Case Report.","authors":"Hayun Jung, Hee-Young Choi, Hwangbo Lee, Jungyul Park","doi":"10.3341/kjo.2023.0125","DOIUrl":"10.3341/kjo.2023.0125","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"167-169"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual Recovery Time in Patients with Ethambutol-induced Toxic Optic Neuropathy.","authors":"Hye Rin An, Byung Joo Lee, Yeji Moon","doi":"10.3341/kjo.2023.0095","DOIUrl":"10.3341/kjo.2023.0095","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to investigate the visual recovery time in patients with ethambutol-induced toxic optic neuropathy (EON) and identify the factors associated with the visual recovery time.</p><p><strong>Methods: </strong>In this retrospective cohort study, we reviewed the medical records of 35 eyes from 35 patients with EON. Visual recovery was defined as a gain of three or more lines from the nadir.</p><p><strong>Results: </strong>Patients were observed following discontinuation of ethambutol (EMB), with the mean follow-up period of 21.0 ± 16.0 months. The visual acuity at nadir was logarithm of the minimum angle of resolution 1.4 ± 0.4, and the final visual acuity was logarithm of the minimum angle of resolution 0.6 ± 0.5. Twenty-seven eyes (77.1%) showed significant visual recovery. In Kaplan-Meier survival, the mean estimated time for visual recovery was 15.2 ± 3.0 months, and 50% of the patients experienced visual recovery at 8.3 ± 2.2 months following EMB discontinuation. Multivariate Cox regression analysis identified several significant risk factors for delayed visual recovery, including duration of EMB medication ≤6 months, period from symptom onset to EMB discontinuation &gt;14 days, and baseline peripapillary retinal nerve fiber layer thickness &gt;98 μm.</p><p><strong>Conclusions: </strong>Our study indicated a mean time of visual recovery of 15 months for EON cases. Therefore, patients diagnosed with EON should be followed up for more than 1 to 2 years to evaluate their visual recovery. Delayed EMB discontinuation, short duration of EMB use, and initial peripapillary retinal nerve fiber layer thickening were associated with delayed visual recovery. Therefore, patients taking EMB should be followed up regularly for early detection of EON and immediate discontinuation of EMB to prevent severe damage to the optic nerve.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"91-97"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Myopia and Obesity in Adults.","authors":"Young Ho Noh, Kyoung In Jung","doi":"10.3341/kjo.2023.0102","DOIUrl":"10.3341/kjo.2023.0102","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the relationship between myopia and obesity through direct measurements of fat content.</p><p><strong>Methods: </strong>A cross-sectional study used a stratified, multistage survey, the Korea National Health and Nutrition Examination Survey (2008-2010). Subjects 19 years or older (n = 10,305) were included. Participants were divided into three groups according to refractive status: myopia (spherical equivalent [SE] ≤ -1.0 diopter [D]), emmetropia (-1.0 D &lt; SE ≤ 1.0 D), and hyperopia (SE &gt; 1.0 D). Obesity was investigated with assessment of fat mass and body mass index or waist circumference. Fat mass was measured with whole-body dual energy x-ray absorptiometry. Body fat percentage was calculated as (total fat mass / body weight × 100).</p><p><strong>Results: </strong>Higher obesity index was found in individuals with myopic eyes after adjustment for age, sex, education level, income status, physical activity, residence, and serum vitamin D level. The significant difference in total body fat percentages among myopia, emmetropia, and hyperopia was significant in the young age group (19-39 years, p &lt; 0.05) but not in the middle age group (40-64 years) and the old age group (≥65 years). Individuals with a higher percentage of total body fat had greater odds ratios for myopia (fourth quartile of body fat; odds ratio, 1.352; 95% confidence interval, 1.178-1.551).</p><p><strong>Conclusions: </strong>An association was found between adiposity and myopia in relatively young adults using direct measurements of fat mass.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"137-146"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140051449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Retinal Hemodynamics in the Optic Nerve Head of Healthy Participants Measured Using Laser Speckle Flowgraphy after a Cold Pressor Test.","authors":"Shogo Sato, Yuki Hashimoto, Ami Sakamoto, Suzuka Nakano, Miki Yoshimura, Toshitaka Yamanokuchi, Takeshi Yoshitomi","doi":"10.3341/kjo.2023.0063","DOIUrl":"10.3341/kjo.2023.0063","url":null,"abstract":"<p><strong>Purpose: </strong>Autoregulation of retinal vessels is stronger than that of choroidal vessels. This study aimed to use laser speckle flowgraphy to determine the time course of changes in retinal hemodynamics of healthy eyes after a cold pressor test.</p><p><strong>Methods: </strong>This prospective study included 44 right eyes of 44 healthy volunteers (age, 21.7 ± 5.0 years). The mean blur rate, which is a quantitative index of the relative blood flow velocity in the retina, was measured using laser speckle flowgraphy. The vessel average of mean blur rate at the optic nerve head, intraocular pressure, systolic blood pressure, diastolic blood pressure, mean blood pressure, heart rate, and ocular perfusion pressure were evaluated at baseline, immediately after the cold pressor test, and 10, 20, and 30 minutes after the test.</p><p><strong>Results: </strong>Immediately after the test (0 minutes), systolic blood pressure, diastolic blood pressure, mean blood pressure, and ocular perfusion pressure were significantly increased compared with those at baseline; however, no changes were observed at 10, 20, and 30 minutes after the test. In contrast, intraocular pressure, heart rate, and the vascular mean blur rate values at the optic nerve head did not change throughout the course of the study.</p><p><strong>Conclusions: </strong>Sympathetic hyperactivity induced by the cold pressor test increased systemic circulatory dynamics, but not retinal circulatory hemodynamics, suggesting the involvement of vascular autoregulation.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"147-155"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140112577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Stab Incision and Eyelid Crease Incision Techniques in Children with Revision Frontalis Sling Surgeries Using Silicone Rods.","authors":"Ceyhun Arici, İbrahim Bulent Buttanri","doi":"10.3341/kjo.2023.0002","DOIUrl":"10.3341/kjo.2023.0002","url":null,"abstract":"<p><strong>Purpose: </strong>To compare stab and eyelid crease incision techniques in revision frontalis sling surgeries using silicone rods.</p><p><strong>Methods: </strong>This retrospective study involved 52 eyes in 48 consecutive pediatric patients who underwent revision frontalis sling surgery between 2008 and 2019. All primary surgeries were performed by making eyelid crease incisions and suturing of silicone rods onto the tarsal plates. The revision surgeries were performed by either making stab incisions over the eyelid through which to pass the silicone rods (group A), or by refixing the same or a new silicone rod to the tarsal plate (group B). The surgical results were compared.</p><p><strong>Results: </strong>The mean follow-up period was 22.4 months (range, 6-62 months) and the mean age of the patients was 6.1 years (range, 1-16 years). There were 28 female and 20 male patients. Surgical success was achieved in 23 of 28 patients (82.1%) in group A, and 12 of 24 patients (50.0%) in group B. The difference between the groups was statistically significant (p = 0.012). Superficial punctate epithelial defects were detected in six group A patients (21.4%) and seven group B patients (29.1%). In group B, lid hematoma occurred in three patients (12.5%) and entropion occurred in three patients (12.5%). The silicone rods were removed from two eyes, and entropion spontaneously resolved in one eye with close follow-up.</p><p><strong>Conclusions: </strong>Using the stab incision technique increases revision frontalis sling surgery success rates when primary surgeries are performed using eyelid crease incisions and suturing silicone rods to the tarsal plates in children.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138816189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractive Predictability between Standard and Total Keratometry during the Femtosecond Laser-Assisted Cataract Surgery with Monofocal Intraocular Lens with Enhanced Intermediate Function.","authors":"Hyunah Lim, Joon Hyuck Jang, Sanghyu Nam, Koeun Lee, Jae Yong Kim, Hungwon Tchah, Hun Lee","doi":"10.3341/kjo.2023.0039","DOIUrl":"10.3341/kjo.2023.0039","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to compare the accuracy of the intraocular lens (IOL) calculation formula using the standard keratometry (K) and total K (TK) during the femtosecond laser-assisted cataract surgery (FLACS) with a monofocal IOL with enhanced intermediate function using currently used formulas.</p><p><strong>Methods: </strong>A retrospective review of 125 eyes from 125 patients who had undergone FLACS with implantation of monofocal IOL with enhanced intermediate function was conducted. The predicted refractive power was calculated using an optical biometer (IOLmaster 700) according to the K and TK in the Barrett Universal II, SRK/T, Haigis, and Holladay 2 formulas. Absolute prediction error (APE) obtained from the actual postoperative refractive outcomes and the refractive error predicted in each formula was compared one month after surgery.</p><p><strong>Results: </strong>Mean APE ranged between 0.29 and 0.39 diopters (D) regardless of the calculation formula and the method of measuring corneal curvature. Significant differences were observed in the APE from the four formulas and the two keratometric measurements (p = 0.014). In a total of 125 eyes from 125 patients, the mean APE was lowest with the Barrett Universal II formula. Across all formulas, both the mean APE and the median APE tended to be lower for K than for TK, although there was no significant difference. Approximately 70% to 80% of the patients were included within 0.5 D of the refractive error across all formulas. The percentage of eyes within 0.5 D of APE outcomes was not statistically different between the K and TK data when using each formula.</p><p><strong>Conclusions: </strong>Keratometric measurements considering the poster corneal curvature did not show any additional advantages when implanting the monofocal IOL with enhanced intermediate function during the FLACS.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"9-16"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138816193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}