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Postoperative Swallowing Function in Patients with Deep Neck Infection. 深颈部感染患者术后吞咽功能。

Biomedicine hub Pub Date : 2023-10-18 eCollection Date: 2023-01-01 DOI: 10.1159/000533526

Shohei Ashizawa, Takuma Hisaoka, Ryoukichi Ikeda, Rina Kamihata, Jun Suzuki, Ai Hirano-Kawamoto, Jun Ohta, Yukio Katori

{"title":"Postoperative Swallowing Function in Patients with Deep Neck Infection.","authors":"Shohei Ashizawa, Takuma Hisaoka, Ryoukichi Ikeda, Rina Kamihata, Jun Suzuki, Ai Hirano-Kawamoto, Jun Ohta, Yukio Katori","doi":"10.1159/000533526","DOIUrl":"10.1159/000533526","url":null,"abstract":"Introduction: Early detection of dysphagia risk, initiating rehabilitation, and resumption of appropriate diet based on swallowing function is important during deep neck infection (DNI) control. This study aimed to evaluate the extent of cervical abscess development, particularly in the deep neck space, and its relationship to postoperative swallowing function.Methods: A retrospective chart review was performed for all DNI cases treated between April 2015 and April 2021. Deep neck spaces were divided into categories based on computed tomography findings. Functional Oral Intake Scale (FOIS) scores of 4 or higher was defined as normal or slight swallowing disorder and 3 or lower as dysphagia.Results: Seventeen cases were included in the analysis. Based on FOIS, 14 cases were classified into the dysphagia group at 2 weeks after surgery, 11 cases at 4 weeks, and 8 cases at 8 weeks. There was no significant difference between the location of the abscess and dysphagia at 2 weeks after surgery. Patients with anterior cervical space abscess significantly increased dysphagia 4 weeks (p = 0.018) and 8 weeks (p = 0.036) after surgery.Conclusion: Abscess formation in the anterior cervical space may be associated with prolonged dysphagia after treatment due to inflammation and scarring of the muscles associated with swallowing.","PeriodicalId":101351,"journal":{"name":"Biomedicine hub","volume":"8 1","pages":"72-78"},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71430804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Population Genome Programs across the Middle East and North Africa: Successes, Challenges, and Future Directions. 中东和北非的人口基因组计划：成功、挑战和未来方向。

Biomedicine hub Pub Date : 2023-09-14 eCollection Date: 2023-01-01 DOI: 10.1159/000530619

Hagar Ateia, Pauline Ogrodzki, Hannah V Wilson, Subhashini Ganesan, Rabih Halwani, Ashish Koshy, Walid A Zaher

{"title":"Population Genome Programs across the Middle East and North Africa: Successes, Challenges, and Future Directions.","authors":"Hagar Ateia, Pauline Ogrodzki, Hannah V Wilson, Subhashini Ganesan, Rabih Halwani, Ashish Koshy, Walid A Zaher","doi":"10.1159/000530619","DOIUrl":"10.1159/000530619","url":null,"abstract":"In this review, we discuss the current state of population genome programs (PGPs) conducted in the Middle East and North African (MENA) region. This region has high prevalence of genetic diseases and significant health challenges as well as being a significantly underrepresented population in public genetic databases. The majority of ongoing PGPs represent regions in Europe, North and South America, South Asia, Australia, and Africa, with little to no descriptive information highlighted only on the MENA Region when it comes to genome programs databases, outcomes, or the challenges that MENA region countries may face establishing their own national programs. This review has identified 6 PGPs currently underway in the MENA region, namely in the Kingdom of Saudi Arabia, Qatar, Egypt, the United Arab Emirates, Bahrain, and Iran. Due to the rapidly growing involvement of the MENA region in national-scale genomic data collection, an increase in representation in public genetic databases is to be expected to occur in the near future. Whilst significant progress is being made in some MENA countries, future initiatives as well as ongoing programs will be facing several challenges related to collaboration, finance, infrastructure and institutional data access, data analysis, sustainability, health records, and biobanks. The review also reiterates the need for ensuring ethical and regulated genomic initiatives which can drive developments in personalized medicine treatments to improve patient prognosis and quality of life.","PeriodicalId":101351,"journal":{"name":"Biomedicine hub","volume":"8 1","pages":"60-71"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71416492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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