Device Pub Date : 2023-12-01 DOI: 10.1016/j.device.2023.100180

Jian Chen, Keju Ji, Chi Xu, Jiahui Zhao, Tingwei Huo, Yi Song, Stanislav N. Gorb, Yi Long, Zhendong Dai

引用次数: 0

A flexible lightweight self-powered wireless metal detector enabled by triboelectric discharge effect 一种利用摩擦放电效应实现的柔性轻量自供电无线金属探测器

Device Pub Date : 2023-11-01 DOI: 10.1016/j.device.2023.100127

Haoyu Wang, Xin Xia, Jingjing Fu, Ziwu Song, Wenbo Ding, Yuan Dai, Yunlong Zi

引用次数: 0

Membrane-encapsulated, moisture-desorptive passive cooling for high-performance, ultra-low-cost, and long-duration electronics thermal management 膜封装，吸湿被动冷却高性能，超低成本，长时间的电子热管理

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100121

Zengguang Sui, Yunren Sui, Zhixiong Ding, Haosheng Lin, Fuxiang Li, Ronggui Yang, Wei Wu

引用次数: 0

Mechanically programming anisotropy in engineered muscle with actuating extracellular matrices 机械编程的各向异性工程肌肉与驱动细胞外基质

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100097

Brandon Rios, Angel Bu, Tara Sheehan, Hiba Kobeissi, Sonika Kohli, Karina Shah, Emma Lejeune, Ritu Raman

{"title":"Mechanically programming anisotropy in engineered muscle with actuating extracellular matrices","authors":"Brandon Rios, Angel Bu, Tara Sheehan, Hiba Kobeissi, Sonika Kohli, Karina Shah, Emma Lejeune, Ritu Raman","doi":"10.1016/j.device.2023.100097","DOIUrl":"https://doi.org/10.1016/j.device.2023.100097","url":null,"abstract":"The hierarchical design and adaptive functionalities of biological tissues are driven by dynamic biochemical, electrical, and mechanical signaling between cells and their extracellular matrices. While existing tools enable monitoring and controlling biochemical and electrical signaling in multicellular systems, there is a significant need for techniques that enable mapping and modulating intercellular mechanical signaling. We have developed a magnetically actuated extracellular matrix that serves as a mechanically active substrate for cells and can program morphological and functional anisotropy in tissues such as skeletal muscle. This method improves the ease and efficiency of programming muscle force directionality and synchronicity for applications ranging from medicine to robotics. Additionally, we present an open-source computational framework enabling quantitative analyses of muscle contractility. Our actuating matrices and accompanying tools are broadly applicable across cell types and hydrogel chemistries, and they can drive fundamental studies in mechanobiology as well as translational applications of engineered tissues in medicine and machines.","PeriodicalId":101324,"journal":{"name":"Device","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135996623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Magnetic matrix actuation for programming tissues 用于编程组织的磁矩阵驱动

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100116

Ioanna Bakaimi, Ritu Raman

引用次数: 0

Implantable microdevices for treating brain tumors 用于治疗脑肿瘤的植入式微型装置

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100068

Alexander G. Yearley, Ruchit V. Patel, Sarah E. Blitz, Sarah Park, Alexander M. Madinger, Jason Li, Benjamin R. Johnston, Pier Paolo Peruzzi, SeungHo Lee, Shriya S. Srinivasan, Joshua D. Bernstock

{"title":"Implantable microdevices for treating brain tumors","authors":"Alexander G. Yearley, Ruchit V. Patel, Sarah E. Blitz, Sarah Park, Alexander M. Madinger, Jason Li, Benjamin R. Johnston, Pier Paolo Peruzzi, SeungHo Lee, Shriya S. Srinivasan, Joshua D. Bernstock","doi":"10.1016/j.device.2023.100068","DOIUrl":"https://doi.org/10.1016/j.device.2023.100068","url":null,"abstract":"Despite extensive research investment, malignant brain tumors continue to be associated with significant morbidity and mortality. Implantable microdevices placed directly in the central nervous system (CNS) represent a promising area of investigation in neuro-oncology. In this review, we provide an overview of the control mechanisms, release kinetics, outcomes, strengths, and limitations of implantable microdevices in clinical and laboratory studies. Eight implantable microdevices that delivered various compounds, including chemotherapy, immunotherapy, and nitric oxide, were identified. Device control functions varied from no control after implantation to active coordination of the release of multiple drugs at different rates. We find that, although the devices can reliably deliver therapeutic compounds to the tumor site, their efficacy in terms of prolonging survival and achieving durable remission remains modest. Our findings reveal a critical narrative that emphasizes the unsolved barriers impeding clinical success of implantable microdevices in neuro-oncology.","PeriodicalId":101324,"journal":{"name":"Device","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136010191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wireless deep-brain neuromodulation using photovoltaics in the second near-infrared spectrum 在第二近红外光谱中使用光伏的无线脑深部神经调制

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100113

Han Cui, Su Zhao, Guosong Hong

引用次数: 0

Domain hyper-languages bring robots together and enable the machine learning community 领域超语言将机器人聚集在一起，使机器学习社区成为可能

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100115

Shakti P. Padhy, Sergei V. Kalinin

引用次数: 0

The Electrolab: An open-source, modular platform for automated characterization of redox-active electrolytes Electrolab:一个开源的模块化平台，用于氧化还原活性电解质的自动表征

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100103

Inkyu Oh, Michael A. Pence, Nikita G. Lukhanin, Oliver Rodríguez, Charles M. Schroeder, Joaquín Rodríguez-López

{"title":"The Electrolab: An open-source, modular platform for automated characterization of redox-active electrolytes","authors":"Inkyu Oh, Michael A. Pence, Nikita G. Lukhanin, Oliver Rodríguez, Charles M. Schroeder, Joaquín Rodríguez-López","doi":"10.1016/j.device.2023.100103","DOIUrl":"https://doi.org/10.1016/j.device.2023.100103","url":null,"abstract":"Electrochemical characterization of redox-active molecules in solution requires exploration of manifold conditions (e.g., concentration, electrolyte type, pH, ionic strength), leading to tedious and time-consuming experiments that are prone to user error. Here, we introduce the Electrolab, a modular, automated electrochemical characterization platform that seamlessly interfaces with common laboratory instrumentation and low-cost electromechanical components. We integrated a gantry-type robot carrying a multipurpose nozzle assembly to dispense and mix solutions as well as degas and clean a cell containing multiplexed microelectrochemical arrays. The system operates using Python code and a universal Arduino-based controller. We demonstrate the Electrolab by autonomously analyzing a redox mediator by performing 200 voltammograms and data analysis steps across a range of conditions. In addition, the Electrolab is used to titrate a redox-active polymer solution to identify conditions for optimizing electrochemical performance. Overall, the Electrolab device enables high-throughput, systematic exploration of redox electrolytes, opening new avenues for closed-loop optimization.","PeriodicalId":101324,"journal":{"name":"Device","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135606888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Injectable miniaturized shape-memory electronic device for continuous glucose monitoring 用于连续血糖监测的可注射小型化形状记忆电子装置

Device Pub Date : 2023-10-01 DOI: 10.1016/j.device.2023.100117

Kang Jiang, Haiyan Wang, Yanyang Long, Yuxin Han, Heng Zhang, Qunhong Weng

{"title":"Injectable miniaturized shape-memory electronic device for continuous glucose monitoring","authors":"Kang Jiang, Haiyan Wang, Yanyang Long, Yuxin Han, Heng Zhang, Qunhong Weng","doi":"10.1016/j.device.2023.100117","DOIUrl":"https://doi.org/10.1016/j.device.2023.100117","url":null,"abstract":"Implantable devices hold promise for revolutionizing personalized healthcare, but the inherent invasiveness of implantation surgeries, among other obstacles, hinders their widespread application. In this work, we present an implantable wireless glucose monitor made with on shape-memory electronic device (SMED) that can be implanted with minimal invasiveness. The device is fabricated by printing an inductive-capacitive (LC) circuit and a poly(3-aminophenylboronic acid) (PAPBA)/glucose oxidase (GOx)/graphene oxide (GO) sensing layer on a shape-memory poly(D,L-lactide-co-caprolactone)-based (PCLAU) layer. To demonstrate, the glucose monitor was rolled up, injected into mice using a syringe, and later recovered to its original planar shape under mild thermal stimulations. The biocompatible SMED has high sensitivity, specificity, and reversible sensing characteristics with a broad linear detection range, providing an accurate and reliable platform for in vivo continuous glucose monitoring. This strategy reduces the wound area by ∼73% and the required healing time by ∼45%, thus effectively addressing the general problem faced by implantable devices.","PeriodicalId":101324,"journal":{"name":"Device","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136059418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Device最新文献