The Turkish journal of pediatrics最新文献

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Gaza's children and the unbearable cost of war - a pediatric perspective on a public health emergency. 加沙儿童与难以承受的战争代价——从儿科角度看突发公共卫生事件。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.6936
Sinem Akgül, Elif Nursel Özmert
{"title":"Gaza's children and the unbearable cost of war - a pediatric perspective on a public health emergency.","authors":"Sinem Akgül, Elif Nursel Özmert","doi":"10.24953/turkjpediatr.2025.6936","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.6936","url":null,"abstract":"","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"443-444"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of serum procalcitonin as a diagnostic tool to differentiate bacterial sepsis from rheumatic flare-ups in children with rheumatic disorders. 评估血清降钙素原作为一种诊断工具,以区分细菌性败血症与风湿病发作的儿童风湿病。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.5969
Aghil Keykhosravi
{"title":"Evaluation of serum procalcitonin as a diagnostic tool to differentiate bacterial sepsis from rheumatic flare-ups in children with rheumatic disorders.","authors":"Aghil Keykhosravi","doi":"10.24953/turkjpediatr.2025.5969","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.5969","url":null,"abstract":"","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"607-608"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of problematic internet use with health-related daily habits in adolescents: evidence from a school-based survey. 青少年有问题的互联网使用与健康相关的日常习惯的关联:来自学校调查的证据。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.5850
Esra Çelik, Ayşe Oflu, Ayşegül Bükülmez
{"title":"Association of problematic internet use with health-related daily habits in adolescents: evidence from a school-based survey.","authors":"Esra Çelik, Ayşe Oflu, Ayşegül Bükülmez","doi":"10.24953/turkjpediatr.2025.5850","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.5850","url":null,"abstract":"<p><strong>Background: </strong>With the development of technology, easier access to the internet and its excessive use have led to problematic internet use (PIU). The prevalence of PIU and its association with lifestyle behaviors in adolescents have become subjects of increasing academic interest. This study aimed to determine the prevalence of PIU among Turkish high school students and to investigate its association with sleep, physical activity and dietary habits.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on high school students between October 2019 and March 2020. Participants completed a questionnaire regarding demographic characteristics, internet use, lifestyle habits and the \"Young Internet Addiction Test-Short Form (YIAT-SF)\".</p><p><strong>Results: </strong>Among the total 951 participants, the mean age was 15.3±1.0 years, 42.3% were female, and the prevalence of PIU was determined as 12.1%. It was shown that having daily internet usage time ≥2 hours on weekdays, having at least one type of sleep problem, having breakfast less than 3 days per week, eating salty snacks ≥3 days per week, consuming sugary-carbonated drinks ≥3 days per week were associated with PIU.</p><p><strong>Conclusions: </strong>PIU is a widespread public health problem that is negatively associated with the daily health habits of adolescents. There is a need for nationwide school screening programs for this problem and rehabilitation of adolescents diagnosed with PIU.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"473-482"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers and facilitators of pediatric adherence to antiretroviral therapy: perspectives from caregivers in Türkiye. 儿童坚持抗逆转录病毒治疗的障碍和促进因素:来自<s:1> rkiye护理人员的观点。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.5730
Özlem Şensoy, Ayfer Aydın, Sema Bayraktar, Ayper Somer, Asuman Demirbuğa, Neslihan Mete Atasever, Elif Dede, Selda Hançerli Törün
{"title":"Barriers and facilitators of pediatric adherence to antiretroviral therapy: perspectives from caregivers in Türkiye.","authors":"Özlem Şensoy, Ayfer Aydın, Sema Bayraktar, Ayper Somer, Asuman Demirbuğa, Neslihan Mete Atasever, Elif Dede, Selda Hançerli Törün","doi":"10.24953/turkjpediatr.2025.5730","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.5730","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to describe barriers and facilitators of the adherence of children with human immunodeficiency virus (HIV) to antiretroviral therapy (ART) from the perspectives of their caregivers.</p><p><strong>Methods: </strong>In-depth interviews were held with the caregivers of 15 children. The collected data were analyzed using thematic analysis procedures. The Consolidated Criteria for Reporting Qualitative Research (COREQ) were followed in the study.</p><p><strong>Results: </strong>The perspectives of caregivers were categorized under four themes and subthemes. Barriers and facilitators of the adherence of children with HIV to ART were categorized into 4 main themes: (1) medication-related, (2) child-related, (3) caregiver-related, and (4) health system-related. The results indicated that understanding the factors that influence pediatric ART adherence is critical to the development of adequate strategies. In addition, disclosure of HIV status to the child is also an important factor affecting drug administration in the social environment.</p><p><strong>Conclusions: </strong>To ensure adherence to lifelong ART, targeted caregiver support through continuous supervision, clear guidance on drug preparation, and strategies for effective administration should be integrated into context-specific interventions that address the combined influence of factors related to the child, medication, healthcare, and of the sociocultural environment.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"501-513"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare pediatric case of immune thrombocytopenia attributed to brucellosis. 一个罕见的儿童病例免疫性血小板减少归因于布鲁氏菌病。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.6166
Elif Kıymet, Mustafa Bilici
{"title":"A rare pediatric case of immune thrombocytopenia attributed to brucellosis.","authors":"Elif Kıymet, Mustafa Bilici","doi":"10.24953/turkjpediatr.2025.6166","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.6166","url":null,"abstract":"<p><strong>Background: </strong>Brucellosis is a zoonotic infection transmitted to humans by ingestion of contaminated unpasteurized dairy products or via direct or indirect contact with infected animals. It is characterized by nonspecific symptoms like fever and joint pain, and laboratory findings including anemia, leukopenia, thrombocytopenia, or rarely pancytopenia. Here we report a case of brucellosis with thrombocytopenia that did not improve despite anti-brucella treatment and required intravenous immunoglobulin treatment.</p><p><strong>Case presentation: </strong>A six-year-old boy from a brucellosis-endemic area presented with fever and fatigue. Initial laboratory tests showed moderate thrombocytopenia and a Brucella agglutination titer of 1/320. Brucella spp. was isolated from blood culture. Rifampicin, trimethoprim-sulfamethoxazole (TMP-SMX), and gentamicin treatment were given to the patient, and clinical improvement followed, with normalization of blood count. However, on day 10, severe thrombocytopenia with epistaxis and ecchymosis developed, suggestive of immune thrombocytopenia (ITP). Intravenous immunoglobulin at a dose of 1000 mg/kg was given, resulting in a rise in platelet count. The patient was discharged with rifampicin and TMP-SMX. During follow-up, his platelet levels returned to normal without the need for additional immunoglobulin, suggesting resolution of Brucella-related immune thrombocytopenia.</p><p><strong>Conclusion: </strong>Brucellosis should be kept in mind in the differential diagnosis of thrombocytopenia in endemic regions. If there is no response to antimicrobial treatment in brucellosis patients presenting with thrombocytopenia, immune thrombocytopenia should be considered.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"590-596"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ivermecatin induces cytotoxic effects in SUP-B15 cell line. 伊维菌素诱导su - b15细胞株的细胞毒作用。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.5831
Olga Rasiyanti Siregar, Arlinda Sari Wahyuni, Ayodhia Pitaloka Pasaribu, Deri Edianto, I Dewa Gede Ugrasena, Rina Amelia, Inke Nadia Diniyanti Lubis, Muhammad Rusda
{"title":"Ivermecatin induces cytotoxic effects in SUP-B15 cell line.","authors":"Olga Rasiyanti Siregar, Arlinda Sari Wahyuni, Ayodhia Pitaloka Pasaribu, Deri Edianto, I Dewa Gede Ugrasena, Rina Amelia, Inke Nadia Diniyanti Lubis, Muhammad Rusda","doi":"10.24953/turkjpediatr.2025.5831","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.5831","url":null,"abstract":"<p><strong>Background: </strong>Glucocorticoids remain the primary treatment for acute lymphoblastic leukemia (ALL) in children. However, glucocorticoid-resistant ALL exhibits increased mortality rates. To overcome resistance and improve management strategies, alternative therapeutic agents are required. Ivermectin (IVM), widely used as an anthelmintic agent, has been reported to possess anticancer properties through various mechanisms. These properties suggest IVM as a potential alternative treatment for ALL. This study aims to evaluate the role of IVM in inducing cytotoxic effects in the ALL cell line SUP-B15.</p><p><strong>Methods: </strong>The ALL cell line SUP-B15 was examined following treatment with IVM at concentrations of 5, 10, and 20 μM. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to assess cytotoxic effects of IVM, including measurements of optical density, cell inhibition, and cell viability.</p><p><strong>Results: </strong>IVM demonstrated inhibitory effects on SUP-B15 cells starting at a low dose of 5 μM. The half maximal inhibitory concentration (IC50) of IVM was 5 µM, showing an inhibitory effect of 54.18 ± 0.03% (95% confidence interval: 54.11-54.25%; p < 0.001). Treatment with 10 μM IVM demonstrated the most significant inhibitory effect (59.05 ± 0.1%) and the lowest cell viability (40.95 ± 0.01%).</p><p><strong>Conclusions: </strong>IVM holds potential as a promising alternative therapeutic agent for the treatment of ALL.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"569-574"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Airway obstruction and gender affect arterial stiffness in children with cystic fibrosis. 气道阻塞和性别影响囊性纤维化儿童的动脉僵硬度。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.5813
Senem Şimşek, Aslıhan Çakmak Önal, Meltem Akgül Erdal, Yasemin Kartal, Murat Timur Budak, Suna Sabuncuoğlu, Nagehan Emiralioğlu, Elmas Ebru Güneş Yalçın, Deniz İnal İnce
{"title":"Airway obstruction and gender affect arterial stiffness in children with cystic fibrosis.","authors":"Senem Şimşek, Aslıhan Çakmak Önal, Meltem Akgül Erdal, Yasemin Kartal, Murat Timur Budak, Suna Sabuncuoğlu, Nagehan Emiralioğlu, Elmas Ebru Güneş Yalçın, Deniz İnal İnce","doi":"10.24953/turkjpediatr.2025.5813","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.5813","url":null,"abstract":"<p><strong>Background: </strong>Vascular changes are observed in children with cystic fibrosis (cwCF), and gender-specific differences may impact arterial stiffness. We aimed to compare arterial stiffness and clinical parameters based on gender in cwCF and to determine the factors affecting arterial stiffness in cwCF.</p><p><strong>Methods: </strong>Fifty-eight cwCF were included. Pulmonary function, lean body mass, handgrip strength, and peak oxygen uptake (VO2peak) were assessed using a cardiopulmonary exercise test. Arterial stiffness (pulse wave velocity [PWV] and augmentation index [AIx@75]) and hemodynamic parameters (resting heart rate [HR] and stroke volume [SV]) were measured using brachial pulse waves. Endothelial function (ICAM-1, sVCAM-1, sE-selectin, VEGF-A, ET-1) was evaluated using blood samples.</p><p><strong>Results: </strong>Female cwCF had significantly lower VO2peak, SV, and PWV, and higher resting HR, AIx@75, and AIx@75-z-score than male cwCF (p<0.05). AIx@75-z-score was associated with gender (r=0.516, p<0.001), age (r= -0.345, p=0.008), lean body mass (r= -0.451, p<0.001), forced expiratory volume in one second (FEV1)-z-score (r= -0.332, p=0.011), handgrip strength (r= -0.466, p<0.001), and VO2peak (r= -0.459, p<0.001) and peak workload (r= -0.527, p<0.001). AIx@75-z-score was not associated with ICAM-1, sVCAM-1, sE-selectin, VEGF-A, or ET-1 (p>0.05). The FEV1-z-score and gender explained 34.6% of the variance in AIx@75-z-score (p<0.05).</p><p><strong>Conclusions: </strong>Female cwCF have more impaired hemodynamics, less maximal exercise capacity, and increased arterial stiffness, indicating a higher cardiovascular risk compared to male cwCF. FEV1 and gender affect arterial stiffness in cwCF. Further studies are necessary to uncover the underlying factors for arterial stiffness and endothelial dysfunction and their clinical effects in cwCF.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"533-545"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mevalonate kinase deficiency in a familial Mediterranean fever endemic region: a single-center experience. 甲羟戊酸激酶缺乏症在家族性地中海热流行地区:单中心经验。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.6015
Elif Kılıç Könte, Ece Aslan, Nergis Akay, Ümit Gül, Esma Aslan, Aybüke Günalp, Fatih Haşlak, Mehmet Yıldız, Amra Adrovic, Sezgin Şahin, Kenan Barut, Özgür Kasapçopur
{"title":"Mevalonate kinase deficiency in a familial Mediterranean fever endemic region: a single-center experience.","authors":"Elif Kılıç Könte, Ece Aslan, Nergis Akay, Ümit Gül, Esma Aslan, Aybüke Günalp, Fatih Haşlak, Mehmet Yıldız, Amra Adrovic, Sezgin Şahin, Kenan Barut, Özgür Kasapçopur","doi":"10.24953/turkjpediatr.2025.6015","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.6015","url":null,"abstract":"<p><strong>Background: </strong>We aimed to document childhood onset mevalonate kinase deficiency (MKD) and to explore treatment responses and diagnostic challenges in regions endemic to familial Mediterranean fever (FMF).</p><p><strong>Methods: </strong>This retrospective study included patients under 18 years of age, diagnosed with MKD and followed for at least six months at the pediatric rheumatology department of Istanbul University - Cerrahpaşa Medical Faculty between 2016 and 2024.</p><p><strong>Results: </strong>Of 33 patients, 51.5% were female, with a median age of symptom onset at 6 (2-17.3) months. Eight patients had a history of tonsillectomy, and seven exhibited an underlying exon 10 Mediterranean FeVer (MEFV) gene mutation. The mean diagnostic delay was 67.6 months, which was longer for those with exon 10 mutations (95.0 months) and those with a history of tonsillectomy (99.5 months). The median duration of attacks was 5 (4-7) days. The median frequency of attacks was 12 (10-24) per year. The most prevalent clinical findings observed during these attacks included malaise (87.8%), arthralgia (69.6%), abdominal pain (63.6%), cervical lymphadenopathy (63.6%), diarrhea (54.5%), and maculopapular rash (51.5%). A total of 30 patients (90.9%) identified pre-attack triggers. Among the patients evaluated, 19 (57.5%) were homozygous for V377I, and 7 (21.2%) had V377I biallelic heterozygous mutation in MVK gene. Cytopenia was observed in 18 patients (54.5%) during episodes, including anemia (39.3%), lymphopenia (24.2%), leukopenia (12.1%), and neutropenia (9%).</p><p><strong>Conclusions: </strong>Patients presenting with periodic fever suggestive of FMF who exhibit atypical features should be evaluated for MKD. Further genetic testing should be performed when atypical clinical findings are present, even in those carrying pathogenic variants in exon 10 of the MEFV gene.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"483-492"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cat, dog, and horse allergies: emerging new insights. 猫,狗和马过敏:新兴的新见解。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.5754
Büşra Koçali, Melike Ocak, Bülent Enis Şekerel
{"title":"Cat, dog, and horse allergies: emerging new insights.","authors":"Büşra Koçali, Melike Ocak, Bülent Enis Şekerel","doi":"10.24953/turkjpediatr.2025.5754","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.5754","url":null,"abstract":"<p><p>Animal allergens, particularly those from cats, dogs, and horses, are significant risk factors for the development of allergic diseases in childhood. Managing animal allergies requires allergen avoidance and, when this is not feasible, specific immunotherapy. Patient history remains the cornerstone of diagnosis, providing the foundation for diagnostic algorithms. Extract-based tests, such as skin prick tests and specific IgE measurements, are essential for confirmation and screening. However, traditional extract-based diagnostic methods have notable limitations, as they are unable to distinguish between primary sensitization and immunological cross-sensitization, and also has the potential for both false negatives and false positives. Polysensitization may arise from either multiple independent sensitizations (co-sensitization) or cross-sensitizations, between homologous allergens. Due to complex cross-reactivity and polysensitization in mammals, extract-based tests are often insufficient in determining the true allergen, so molecular allergen testing should be used. Even with molecular testing, there is no consensus on how to define complex and intriguing sensitization patterns in mammals. In this report, we review the literature on cat, dog, and horse allergies and propose a novel approach to identifying complex sensitization patterns based on the current state of knowledge. We recommend that the evaluation of cat, dog, and horse allergies should begin with investigating genuine sensitization to Fel d 1, Can f 4/5, and Equ c 4, respectively. As a subsequent step, we propose a practical approach to determine primary allergen sensitization within the lipocalin group. Secondary sensitizations should then be evaluated in the context of recent contact history and presenting symptoms. While serum albumin is less strongly associated with true animal allergies, we suggest that it may serve as a complementary marker when considered alongside cross-reactive food allergen molecules.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"445-454"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful percutaneous retrieval of fractured umbilical artery catheter in a very low birth weight preterm neonate. 低出生体重早产儿脐动脉导管断裂经皮置换术成功。
The Turkish journal of pediatrics Pub Date : 2025-09-01 DOI: 10.24953/turkjpediatr.2025.6075
Gowtham Reddy Nomula, Anupam Bhambhani, Keshav Kumar Pathak, Rehana Aliyar, Rajnish Kumar
{"title":"Successful percutaneous retrieval of fractured umbilical artery catheter in a very low birth weight preterm neonate.","authors":"Gowtham Reddy Nomula, Anupam Bhambhani, Keshav Kumar Pathak, Rehana Aliyar, Rajnish Kumar","doi":"10.24953/turkjpediatr.2025.6075","DOIUrl":"https://doi.org/10.24953/turkjpediatr.2025.6075","url":null,"abstract":"<p><strong>Background: </strong>Umbilical arterial catheterisation is a common intervention performed in the neonatal intensive care unit (NICU) especially in extremely preterm and extremely low birth weight neonates. Rarely catheter fracture or breakage can occur, leaving behind part of the catheter in the aorta. A handful of cases have been reported in the literature, with the majority being managed surgically. There is no well-established protocol or consensus on the optimal management of such situations, leaving clinicians to rely on innovative and individualized approaches to address this critical situation.</p><p><strong>Case presentation: </strong>We report the successful percutaneous retrieval of a fractured umbilical artery catheter (UAC) from the aorta of a very low birth weight preterm neonate born at 28 weeks of gestation, who was undergoing treatment for neonatal sepsis at our hospital's NICU. The fractured catheter was retrieved via the right femoral artery using an improvised snare created by double-folding and inserting a 300 cm, 0.014-inch coronary guidewire into a Judkins Right (JR) 6F coronary guide catheter, forming a loop that protruded from its distal end. Following retrieval, the patient exhibited transiently weak pulses and decreased limb movement in the accessed limb. A duplex colour Doppler scan was performed which ruled out thrombosis or dissection. It was attributed to a spasm of the common femoral artery, which recovered eventually.</p><p><strong>Conclusion: </strong>This case demonstrates the feasibility and effectiveness of successful percutaneous removal of the fractured UAC from the aorta in very low birth weight preterm neonates and underscores the importance of innovative use of improvising hardware, appropriating it to the small size of the patient.</p>","PeriodicalId":101314,"journal":{"name":"The Turkish journal of pediatrics","volume":"67 4","pages":"575-580"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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