Environmental analysis, health and toxicology最新文献_第9页

Carcinogenic and non-carcinogenic risk assessment of consuming metal-laden wild mushrooms in Nigeria: Analyses from field based and systematic review studies. 尼日利亚食用含金属野生蘑菇的致癌性和非致癌性风险评估:基于实地和系统审查研究的分析。

Environmental analysis, health and toxicology Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023013

K. S. Chukwuka, S. O. Adesida, C. Alimba

{"title":"Carcinogenic and non-carcinogenic risk assessment of consuming metal-laden wild mushrooms in Nigeria: Analyses from field based and systematic review studies.","authors":"K. S. Chukwuka, S. O. Adesida, C. Alimba","doi":"10.5620/eaht.2023013","DOIUrl":"https://doi.org/10.5620/eaht.2023013","url":null,"abstract":"This study investigated the potential health risk associated with the consumption of metal-laden mushrooms in Nigeria. Concentrations of Pb, Cd, Cr, Cu, Ni, Zn and Al in wild mushrooms collected from the Nigerian environment were measured using atomic absorption spectrometer. Also, systematic analysis of articles on metal accumulation in mushrooms from Nigeria were obtained from scientific databases. Using hazard model indices, the metal concentration in mushrooms were evaluated for their potential carcinogenic and non-carcinogenic health risk when consumed by adults and children. Zn and Cd, respectively, had the highest and lowest mean concentrations (mg kg-1) in the analysed mushrooms from the field study, while Fe and Co, respectively, had the highest and lowest mean concentrations (mg kg-1) in the systematically reviewed articles. In the field study, the percentage distribution of THQ of the heavy metals greater than 1 was 0% and 42.85% for adults and children respectively. While for the systematic study, 30% and 50% of the heavy metals for adults and children respectively exceeded the limit of 1. The hazard indices obtained from both the systematic and field studies for both age groups were all >1, indicating significant health risk. The findings from both the systematic and field studies revealed that consuming metal-laden mushrooms by adults and children increases the carcinogenic risk to Cd, Cr, and Ni since they exceeded the acceptable limit of 1E-04 stated by USEPA guideline. Based on the findings from the systematic and field studies, it suggests that consuming mushrooms collected from metal polluted substrates increases carcinogenic and non-carcinogenic health risk among Nigerians.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"20 1","pages":"e2023013-0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75295646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biochemical and histopathological changes in livers of rats poisoned with aluminum phosphide and treated with carrot extract 磷化铝中毒和胡萝卜提取物处理大鼠肝脏的生化和组织病理学变化

Environmental analysis, health and toxicology Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023014

A. H. Al-Safar, Rafat A. Mohammed Jawad, H. Khayoon, M. A. Alsaadawi, K. H. Zenad, Z. Saeed, M. Alkhaled

{"title":"Biochemical and histopathological changes in livers of rats poisoned with aluminum phosphide and treated with carrot extract","authors":"A. H. Al-Safar, Rafat A. Mohammed Jawad, H. Khayoon, M. A. Alsaadawi, K. H. Zenad, Z. Saeed, M. Alkhaled","doi":"10.5620/eaht.2023014","DOIUrl":"https://doi.org/10.5620/eaht.2023014","url":null,"abstract":"The experimental studies of Aluminum Phosphide (AP) poisoning in rats revealed several clinical and pathological signs such as hemorrhage, sinusoidal dilatation, bile stasis, centrilobular necrosis, Kupffer cell hyperplasia, infiltration by mononuclear cells, and fatty infiltration in the liver tissues. This paper aimed to show the impact of carrots on the toxic effect of AP on the livers of adult rats (female). To investigate some biochemical and histopathological changes effects of AP in rats, sixty white female rats were equally divided into four groups, the first group (G1) was administered orally with 3mg/kg/ body weight of AP, the second group (G2) was orally treated with AP and 10% carrot extract at the same time. The third group (G3) administrated 10% carrot extract only. The fourth (G4) group was the negative control and was treated with distilled water only. The experiments continued for a month at the animal house of the Veterinary Medicine College of Baghdad University. The results revealed that high levels of liver enzymes and bilirubin were induced in G1 with decreasing total protein levels. The pathological examination revealed the presence of marked proliferation of Kupffer cells in G1 livers. However, the G2 group showed slight infiltration of lymphocytes in sinusoids. The pathological changes in the livers of G3 group showed slight cloudy swelling in hepatocytes compared with the normal texture of hepatocytes in G4. The data of this experiment showed that treatment with carrot extract significantly decreases the elevation in the level of liver function enzymes in animal poisoned with AP. In addition, treatment with carrot extract reduces the severe damage in the hepatic tissue that occurred in rats treated with AP only. In general, it could be concluded that treatment with carrot extract provides a remedial effect against the hepatotoxicity that is resulted from exposure to AP.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78795092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of triclosan and human infertility: A systematic review. 三氯生与人类不孕症的关系:一项系统综述。

Environmental analysis, health and toxicology Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023015

Belén Daza-Rodríguez, Dilia Aparicio-Marenco, Johana Márquez-Lázaro

{"title":"Association of triclosan and human infertility: A systematic review.","authors":"Belén Daza-Rodríguez, Dilia Aparicio-Marenco, Johana Márquez-Lázaro","doi":"10.5620/eaht.2023015","DOIUrl":"https://doi.org/10.5620/eaht.2023015","url":null,"abstract":"Triclosan (TCS) is a chemical compound, which has antibacterial, antiviral, and antifungal properties. TCS is considered an endocrine-disrupting chemical, which has been shown to interfere with developmental, behavioral, and reproductive outcomes in biological models and cell cultures. However, implications about exposure to TCS and human infertility are rare. Thus, the main of this review is summarize the available evidence of the association between triclosan exposure on human infertility. For this, systematic review was conducted following the recommendations established in Report of Systematic Reviews and Meta-Analyses guide (PRISMA). Initially, an electronic search in MEDLINE (via PubMed) and Science direct was performed. The methodological quality of the included studies was verified through the Joanna Briggs Institute (JBI) checklists. All selection and data extraction processes were carried out independently by two reviewers. The evidence was organized and presented using tables and narrative synthesis. There is lacking evidence about the association between triclosan and human infertility. Overall, no association between triclosan and infertility was found. However, semen quality and ovarian reserve are susceptible to triclosan exposure. Thus, future studies are still needed to better elucidate the associations between triclosan and infertility outcomes.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"34 1","pages":"e2023015-0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85932521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Toxic elements in shellfish from three rivers in Niger Delta, Nigeria: bioaccumulation, dietary intake, and human health risk assessment 尼日利亚尼日尔三角洲三条河流贝类中潜在有毒元素:生物积累、膳食摄入和人类健康风险评估

Environmental analysis, health and toxicology Pub Date : 2023-06-01 DOI: 10.5620/eaht.2023011

B. Onyegeme-okerenta, Levi Okeinaye West

{"title":"Potential Toxic elements in shellfish from three rivers in Niger Delta, Nigeria: bioaccumulation, dietary intake, and human health risk assessment","authors":"B. Onyegeme-okerenta, Levi Okeinaye West","doi":"10.5620/eaht.2023011","DOIUrl":"https://doi.org/10.5620/eaht.2023011","url":null,"abstract":"Human health risks associated with the consumption of three shellfish (Penaeus monodon, Crassostrea rhizophorae, and Tympanostomus fuscatus) harvested from the Buguma, Krakrama, and Bonny Rivers in the Niger Delta region were evaluated in this study. The bioaccumulation of potential toxic elements (PTEs) [Arsenic (As), Cadmium (Cd), Chromium (Cr), Lead (Pb), and Nickel (Ni)] was analyzed using atomic absorption spectrophotometry (AAS). The pollution index (PPI), estimated daily intake (EDI), target hazard quotient (THQ), total hazard index (HI), target cancer risk (CR), and total cancer risk (TCR) were evaluated for potential human health risks. The bioaccumulation levels of PTEs in shellfish samples followed the order: Ni > Cr > Pb > Cd > As and were above standard recommended limits except for inorganic As levels observed in T. fuscatus and P. monodon samples from Krakrama and Bonny and C. rhizophorae from Bonny river. The EDI values for iAs, Cr, and Ni were lower than the tolerable daily intake (TDI), however, the EDI of Cd for children in P. monodon (4.6E-03 mg kg-1day-1), T. fuscatus (1.7E-03 mg kg-1day-1) and C. rhizophorae (1.4E-03 mg kg-1day-1) from Buguma were higher than the TDI value (8.00E-04 mg kg-1day-1). The HI values were above 1. The total cancer risk (TCR) values of all analyzed PTEs for all the shellfish species from the rivers for children and adults ranged from 8.69E-04 to 2.47E-03 and 1.86E-03 to 5.30E-03 respectively and these were higher than the priority risk level (1E-04), hence, the need to monitor shellfish consumption in the study area.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81707323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cobalt-induced neuro-behavioural alterations are accompanied by profound Purkinje cell and gut-associated responses in rats 在大鼠中，钴诱导的神经行为改变伴随着深刻的浦肯野细胞和肠道相关反应

Environmental analysis, health and toxicology Pub Date : 2023-05-17 DOI: 10.5620/eaht.2023010

A. Akinrinde, K. Adigun, O. Mustapha

{"title":"Cobalt-induced neuro-behavioural alterations are accompanied by profound Purkinje cell and gut-associated responses in rats","authors":"A. Akinrinde, K. Adigun, O. Mustapha","doi":"10.5620/eaht.2023010","DOIUrl":"https://doi.org/10.5620/eaht.2023010","url":null,"abstract":"Metal ions including cobalt (Co) ions reportedly exhibit neurotoxic and antimicrobial properties. We hypothesized that oral exposure to Co may have implications for gut-dysbiosis with possible alterations of microbiota-gut-brain signaling in the host. In this preliminary study, we sought to examine whether exposure of male Wistar rats to cobalt chloride (CoCl2) at 0, 25, 50 and 100 mg/kg for two weeks affects select neurobehavioural indices, vagus nerve and brain morphology along with evaluation of associated changes in faecal bacterial flora, faecal fatty acids and the morphology of the intestines. CoCl2-exposed rats showed a dose-dependent reduction in hanging latency in the hanging wire (HW) test, reduced tendency to recognize novel objects in a Novel Object recognition (NOR) test, but increased interaction with open arms in the elevated plus maze (EPM) test, compared to controls. There were dose-dependent reductions in total heterotrophic count, coliforms, E. coli, Enterococcal and Lactobacilli counts in the faeces. Administration of CoCl2 at 100 mg/kg evoked the appearance of unsaturated fatty acids including palmitoleic, oleic and linoleic acids in the faeces as detected by gas chromatography-flame ion detection (GD-FID) analysis using fatty acid methyl esters (FAME) standards. Histopathological examination revealed chromatolysis of Purkinje cells in the cerebellum, although no significant lesions were present in the vagus nerve isolated from all the groups. In the intestines, there was moderate to severe infiltration of inflammatory cells into the duodenum, ileum, jejunum and colon while villi erosions were seen prominently in the ileum. These initial findings suggest that short-term exposure to Co can lead to gut-associated changes that may underlie neurotoxicity and alterations in behavior induced by Co.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84607030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mortality and morbidity assessment attributed to short- and long-term exposure to fine particles in ambient air of Agadir city, Morocco: The AirQ model approach 短期和长期暴露于摩洛哥阿加迪尔市环境空气中细颗粒物的死亡率和发病率评估:AirQ模型方法

Environmental analysis, health and toxicology Pub Date : 2023-05-12 DOI: 10.5620/eaht.2023009

Youssef Bouchriti, A. Korrida, Mohamed Ait Haddou, A. Achbani, H. Sine, J. Rida, Hayat Sine, Rachid Amiha, B. Kabbachi

{"title":"Mortality and morbidity assessment attributed to short- and long-term exposure to fine particles in ambient air of Agadir city, Morocco: The AirQ model approach","authors":"Youssef Bouchriti, A. Korrida, Mohamed Ait Haddou, A. Achbani, H. Sine, J. Rida, Hayat Sine, Rachid Amiha, B. Kabbachi","doi":"10.5620/eaht.2023009","DOIUrl":"https://doi.org/10.5620/eaht.2023009","url":null,"abstract":"It is well established that respiratory mortality and morbidity are associated with high concentrations of fine particles such as PM2.5. The aim of this study was to evaluate the long- and short-term impacts of PM2.5 on the population of Agadir, Morocco, using AirQ 2.1.1 software. The mean PM2.5 values were obtained from data collected at three sites. Baseline incidence data were obtained from the literature, and relative risk (RR) values were referenced from the World Health Organization. This study quantified long-term total mortality (LT-TM), lung cancer mortality (LT-LC), morbidity from acute lower respiratory tract infections (LT-ALRI), and morbidity from chronic obstructive pulmonary disease (LT-COPD), as well as short-term total mortality (ST-TM). The attributable proportions (AP) of LT-TM and LT-LC were estimated to 14.19% and 18.42%, respectively. Their excess deaths were estimated to 279 and 11 persons, respectively, and their RRs to 1.16 (95% CI: 1.10-1.22) and 1.23 (95% CI: 1.12-1.37), respectively. Furthermore, the AP of LT-ALRI and LT-COPD were estimated to 14.36% and 15.68%, respectively, their excess deaths to 33 and 4, and their RRs to 1.17 (95% CI: 1.11-1.31) and 1.19 (95% CI: 1.00-1.02), respectively. In comparison, the AP of ST-TM was estimated to 1.27%, with a 25-person excess death rate. This study was conducted to inform decision-making and to promote local policies on ambient air quality.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"457 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76063264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

In vitro and in vivo evaluation of the genotoxicity of titanium dioxide, GST 体外和体内评价二氧化钛的遗传毒性

Environmental analysis, health and toxicology Pub Date : 2023-05-03 DOI: 10.5620/eaht.2023008

Ji-Soo Kim, Myung-Hwan Jeong, Heung-Sik Seo, Myeong-Kyu Park, Hee Ju Park, Seong-Soon Nah

{"title":"In vitro and in vivo evaluation of the genotoxicity of titanium dioxide, GST","authors":"Ji-Soo Kim, Myung-Hwan Jeong, Heung-Sik Seo, Myeong-Kyu Park, Hee Ju Park, Seong-Soon Nah","doi":"10.5620/eaht.2023008","DOIUrl":"https://doi.org/10.5620/eaht.2023008","url":null,"abstract":"Titanium dioxide (TiO2) was used in various applications in a wide range of products including food, cosmetics and photocatalyst. General toxicity studies of titanium dioxide, GST (Green Sludge Titanium) have been investigated in several reports, whereas studies concerning mutagenicity and genotoxicity have not been elucidated. Herein, we investigated the potential mutagenicity and genotoxicity of GST by genetic toxicology testing. The bacterial reverse mutation test was conducted by the pre-incubation method in the presence and absence of metabolic activation system (S9 mixture). The chromosome aberration test was performed using cultured Chinese hamster lung cell line in the absence and presence of S9 mixture. The micronucleus test was performed by using specific pathogen-free male ICR mice. Genotoxicity tests were conducted following the test guidelines of the Organisation for Economic Cooperation and Development with application of Good Laboratory Practice. No statistically significant increases were found in the bacterial reverse mutation test, in vitro chromosome aberration test, and in vivo micronucleus test when tested for induction of genotoxicity in GST. These results suggest that GST did not induce mutagenicity and genotoxicity in both in vitro and in vivo system.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88338754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of knowledge, attitude, perceptions and risk assessment among workers in e-waste recycling shops, Thailand 泰国电子废物回收店工人的知识、态度、观念及风险评估

Environmental analysis, health and toxicology Pub Date : 2022-03-01 DOI: 10.5620/eaht.2022003

Somsiri Decharat, Peeranart Kiddee

{"title":"Assessment of knowledge, attitude, perceptions and risk assessment among workers in e-waste recycling shops, Thailand","authors":"Somsiri Decharat, Peeranart Kiddee","doi":"10.5620/eaht.2022003","DOIUrl":"https://doi.org/10.5620/eaht.2022003","url":null,"abstract":"To study the knowledge, attitudes and perceptions, to study the health effects, and to investigate the concentration of Pb and Cd in indoor dust samples, drinking water samples, and personal air samples and to assess the health risk among workers who worked at e-waste recycling shops in the southern region, Thailand. This cross-sectional descriptive study was conducted among workers from 136 electronic waste recycling stores in Southern Thailand, between January and July 2021. The study questionnaire was given to the 272 e-waste workers participating. Indoor dust, drinking water, and personal air samples were collected 27 e-waste shops and the concentrations of Pb and Cd in all samples were determined by graphite furnace atomic absorption spectrometry. Descriptive statistics and the simple linear regression were used to analyze. Overall, 176 employees (64.7%) suffered nasal irritation, 181 employees (66.5%) reported coughing/sneezing, and 163 employees (59.9%) had inconvenient breathing/jamming symptoms. Also, 158 employees (58.1%) had skin peeling symptoms, and 188 employees (69.1%) had muscle aches. The results indicate the positive influence of increasing knowledge and attitudes on the average practice score. The hazardous index (HI)-values of indoor dust samples, drinking water samples, and personal air samples were less than 1, was considered health-protective. The results will provide the direct evidence needed by e-waste managers to warn learners. Thus, there is a need for education programme to increase knowledge among the workers. In addition, information dissemination, involvement with organizations and associations is a necessity for workers in this study.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78695186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Health effects of sodium hypochlorite: review of published case reports 次氯酸钠对健康的影响:对已发表病例报告的回顾

Environmental analysis, health and toxicology Pub Date : 2022-03-01 DOI: 10.5620/eaht.2022006

Insung Chung, Hyeseung Ryu, Seong-yong Yoon, J. Ha

引用次数: 12

Evaluation of transdermal exposure of phthalates in children’s products 儿童产品中邻苯二甲酸酯经皮暴露的评估

Environmental analysis, health and toxicology Pub Date : 2022-03-01 DOI: 10.5620/eaht.2022005

Jihye Hwang, Young-Wook Lim, Ji-Yeon Yang, Dong-chun Shin

{"title":"Evaluation of transdermal exposure of phthalates in children’s products","authors":"Jihye Hwang, Young-Wook Lim, Ji-Yeon Yang, Dong-chun Shin","doi":"10.5620/eaht.2022005","DOIUrl":"https://doi.org/10.5620/eaht.2022005","url":null,"abstract":"In this study, 16 children’s products with the highest detection potential of phthalates were selected, and a phthalate assay and transdermal delivery analysis (NIER, US EPA Wipe [stress condition], US EPA Wipe [physiological condition], and US EPA Hand Wipe) were conducted with these products. The content of 6 controlled phthalates (DBP, BBP, DEHP, DNOP, DINP, and DIDP) was measured and most products contained more phthalates than the regulated guidelines (a total content of 6 phthalates to be ≤0.1%). For transdermal delivery, all items were found to be lower in the NIER transdermal delivery test method compared to the US EPA Hand Wipe (stress condition and physiological condition) transdermal delivery test method. For the US EPA Hand Wipe (stress condition and physiological condition) transdermal delivery test method, a similar result was observed, except for DINP. The average daily dose (ADD) estimated by determining the exposure algorithm for each transdermal delivery test method was highest in mats with a large contacting surface area and a long exposure time in the respective test methods. Conclusively, there was a difference between the NIER transdermal delivery test method and the US EPA Wipe transdermal delivery test method.","PeriodicalId":101307,"journal":{"name":"Environmental analysis, health and toxicology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77445399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0