Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie最新文献_第9页

Immunoglobulins under the Influence of Nonspecific Factors 非特异性因素影响下的免疫球蛋白

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80048-0

Maria Wagner, Vladimír Wagner , Jaroslav Kříiž, Drahomíra Wokounová

{"title":"Immunoglobulins under the Influence of Nonspecific Factors","authors":"Maria Wagner, Vladimír Wagner , Jaroslav Kříiž, Drahomíra Wokounová","doi":"10.1016/S0300-872X(76)80048-0","DOIUrl":"10.1016/S0300-872X(76)80048-0","url":null,"abstract":"<div><p>The levels of IgG, IgA, IgM, lysozyme, agglutinins against B. pertussis and B. parapertussis were followed in the blood serum of 306 children 9–10 years old in 3 areas of Central Bohemian region. In children dwelling in areas with more polluted air significantly higher levels of serum lysozyme and of parapertussis antibodies were found by the t-test. The distribution of these values shows significant differences between more polluted areas in comparison with lowerpollution area also in Kolmogorov-Smirnov test.</p><p>The average levels of Ig approached statistically critical values but did not reach them, but significant differences in the distribution of values of IgG and IgA were shown by the F-test and x<sup>2</sup>-test between lightly and heavily polluted areas. The values of immunological reactions in polluted areas were always higher than in the non-polluted group. This provides evidence for a hypothesis about a stimulatory effect of polluted air on immunological mechanisms in child population.</p><p>The higher values of IgM observed recently by other authors in women were shown in girls of 9–10 years.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 1","pages":"Pages 22-31"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-872X(76)80048-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125792577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Effect of Cyclophosphamide on the Immune Response to Sheep Erythrocytes in the Mouse 环磷酰胺对小鼠对绵羊红细胞免疫反应的影响

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80046-7

S. Mackiewicz , U. Mackiewicz, K. Burchardt, J. Konys

引用次数: 0

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80057-1

H. Brandis

引用次数: 0

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80053-4

M. Krüpe

引用次数: 0

Guinea Pig Histocompatibility Antigens 豚鼠组织相容性抗原

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80052-2

K.J. Tötterman, E. Müller, A.L. De Weck

{"title":"Guinea Pig Histocompatibility Antigens","authors":"K.J. Tötterman, E. Müller, A.L. De Weck","doi":"10.1016/S0300-872X(76)80052-2","DOIUrl":"10.1016/S0300-872X(76)80052-2","url":null,"abstract":"<div><p>The normal lymphocyte transfer (NLT) reaction occurring upon intradermal injection of lymphocytes into a normal recipient may be considered as a kind of mixed lymphocyte reaction in vivo. In previous experiments, we have defined serologically a number of guinea pig lymphocyte antigens, controlled either by a GPL-A locus (equivalent of H-2 D locus in mice) or by a so-called I region (equivalent to the I region in mice). The I region also appears to control a number of immune response genes in the guinea pig.</p><p>Using guinea pig inbred strains (such as 2, 13, OM<sub>3</sub>, BE), guinea pig families homozygous for their GPL-A antigens and serologically characterized outbreds, it has been possible to show that antigens of the I region probably play a major role in NLT reactions. No NLT reactions occur among outbred animals of a closed colony which have been bred to homozygozity for their GPL-A antigens and thereby probably possess haplotype homozygozity for their major histocompatibility complex. The NLT reaction among serologically characterized guinea pigs may become a convenient way to detect new specificities and recombinant progeny.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 1","pages":"Pages 69-77"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-872X(76)80052-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115715008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Mikrofluorometrischer Nachweis von Thyreoglobulin-Antikörpern mit dem definierten Antigen-Substrat-System (DASS)1) 3 .用抗原病毒链证明百里菌素病毒

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80050-9

W. Knapp , H. Ludwig, G. Schernthaner, R. Höfer, C. Steffen

引用次数: 0

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80055-8

J. Morenz, H. Hudemann

引用次数: 0

Cr-Releasing Cytotoxicity Tests: Study of Parameters Influencing their Reliability cr释放细胞毒性试验:影响其可靠性的参数研究

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80045-5

Jelka Gabrilovac , M. Boranić , M. Radačić

引用次数: 1

Local and Systemic Opsonic Adherent, Hemagglutinating and Rosette Forming Activity in Mice induced by Respiratory Immunization with Sheep Red Blood Cells 绵羊红细胞呼吸免疫诱导小鼠的局部和全身声速粘附、血凝和花环形成活性

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80051-0

Shmuel Birnbaum , Moshe Pinto

{"title":"Local and Systemic Opsonic Adherent, Hemagglutinating and Rosette Forming Activity in Mice induced by Respiratory Immunization with Sheep Red Blood Cells","authors":"Shmuel Birnbaum , Moshe Pinto","doi":"10.1016/S0300-872X(76)80051-0","DOIUrl":"10.1016/S0300-872X(76)80051-0","url":null,"abstract":"<div><p>The humoral response in mice after intranasal (IN) instillation of sheep red blood cells (SRBC) was compared to that produced by intraperitoneal route of immunization. Study of opsonic adherent (passive indirect cytophilic) and hemagglutinating antibody levels in serum and bronchial washings after repeated challenge with SRBC showed that serum antibody titers following respiratory immunization does not differ from the general patterns of a humoral antibody response. The bronchial wash antibody titer was higher than the serum titer as calculated per globulin unit. In contrast, the appearance of measurable antibodies in the bronchial washings after repeated intraperitoneal immunization was delayed and in low titer. B. pertussis vaccine administered in conjunction with SRBC was found to be an excellent adjuvant in the intranasal route of immunization. A single administration of SRBC-Pertussis evoked a considerable adjuvant effect as measured by hemagglutinating and opsonic adherent tests. Monospecific anti-mouse IgG nullified the hemagglutinating and opsonic adherent activity of the bronchial washings, while monospecific anti-mouse IgM had no effect in either activity.</p><p>Lung and spleen cells capable of forming rosettes with SRBC of intranasally immunized and control mice were counted. Mean response on day 14 was 6 × 10<sup>3</sup> rosettes per million lung lymphoid cells in comparison with less than 10<sup>3</sup> in control mice. No difference was found in the number of rosette-forming cells in the spleen of control and intranasally immunized mice.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 1","pages":"Pages 61-68"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-872X(76)80051-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131556131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-03-01 DOI: 10.1016/S0300-872X(76)80054-6

Döhner

引用次数: 0