Helmut Brade , Magdalena Klein , W.A. Kurt Schmidt
{"title":"Bildung und Persistenz latexagglutinationshemmender Antikörper in Rhesusaffen nach Infektion mit Coxsackievirus Typ B4","authors":"Helmut Brade , Magdalena Klein , W.A. Kurt Schmidt","doi":"10.1016/S0340-904X(76)80030-9","DOIUrl":"10.1016/S0340-904X(76)80030-9","url":null,"abstract":"<div><p>The formation and persistence of latexagglutination-inhibiting (LAH), neutralizing (N), and complement-fixing (CF) antibodies were in Rhesus monkeys after experimental infection with coxsackievirus type B4.</p><p>In all 3 animals the LAH antibodies showed a significant decrease between the 49th and 56th day after infection. In 2 cases the CF antibodies declined to 25% of their maximum titer on day 84 after infection, and in 2 animals the N antibodies declined between the 70th and 84th day after infection.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 5","pages":"Pages 461-465"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(76)80030-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81093541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic Differences Between Endotoxin-Sensitive and Resistant C3H Mice","authors":"L.G. Gurtler , W.R. Rank","doi":"10.1016/S0340-904X(76)80026-7","DOIUrl":"10.1016/S0340-904X(76)80026-7","url":null,"abstract":"<div><p>The 2 related mouse strains C3H/HeJ and C3H/Han differ in their response to endotoxin. C3H/HeJ mice are endotoxin-resistant, C3H/Han mice are - like all other mice - endotoxin-sensitive. The uptake of fluorescent intraperitoneally injected lipopolysaccharide was similar in both mouse strains. The intraperitoneal injection of lipopolysaccharide produced a higher mobilization of neutrophil granulocytes in resistant C3H/HeJ mice than in C3H/Han mice. An opposite pattern of mobilization of neutrophil granulocytes could be observed after injection of the prostaglandins E 1, E 2, and F 1 α; when both mouse strains were compared, a normal mobilization was observed in C3H/Han mice C3H/HeJ mice showed a markedly decreased mobilization.</p><p>If the difference between the 2 strains resides in a single gene locus it is to be assumed that lipopolysaccharide resistance is controlled by the same gene which also effects an impaired response to neutrophil mobilization after prostaglandin application.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 5","pages":"Pages 420-429"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(76)80026-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86058461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subpopulations of Blood Lymphocytes in Patients with Rheumatoid Arthritis","authors":"Ewa Celińska , Renata Brelińska , S. Mackiewicz","doi":"10.1016/S0340-904X(76)80029-2","DOIUrl":"10.1016/S0340-904X(76)80029-2","url":null,"abstract":"<div><p>The peripheral blood lymphocyte subpopulations of 18 patients with rheumatoid arthritis were compared with those of 10 healthy donors using minor modifications of the mixed immunofluorescence and rosette test (1), rosette test using human 0 RhD erythrocytes coated with anti-RhD antibodies (2) and the mixed rosette test (3).</p><p>It was found that the percentages of lymphocytes exhibiting both immunoglobulin receptors and receptors for sheep erythrocytes, and lymphocytes with receptors for Fc part of IgG in the rheumatoid patients were increased. A hypothesis for the origin of these subpopulations is discussed.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 5","pages":"Pages 455-460"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(76)80029-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88291608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Active Immunization Against Tetanus of Children Suffering with Diabetes mellitus","authors":"K. Solomonova , M. Damiyanova, M. Betovska","doi":"10.1016/S0340-904X(76)80023-1","DOIUrl":"10.1016/S0340-904X(76)80023-1","url":null,"abstract":"<div><p>The authors report on the anti-tetanus reimmunization of 76 diabetic children and adolescents hospitalized in the Diabetic Ward for Children in Varshetz. All patients had insulin-deficient diabetes and they were treated with insulin Lente. The diet was limited and physiological. Thirty-nine of the patients had diabetes in a state of compensation, while the remaining 37 patients were in a state of decompensation without acetonuria.</p><p>The reimmunization was well tolerated and no strong general and local reactions were observed.</p><p>The authors do not establish statistically significant differences during an overnight period in the blood sugar level and the degree of glucosuria before and after reimmunization. They conclude that the immunization does not disturb the metabolic processes.</p><p>On the 20th day after the reimmunization 98.6% of the children showed a high antitoxic titre, which suggests that the capacity of diabetics to elaborate a good anti-tetanus immunity is unimpaired.</p><p>It is recommended that patients with diabetes should be immunized against tetanus during a stage of stabilized diabetes metabolism.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 5","pages":"Pages 383-390"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(76)80023-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86451293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deviated Lysis: Transfer of Complement Lytic Activity to Unsensitized Cells II. Generation of the Activity by Inulin and by Antigen Antibody Complexes","authors":"U. Rother, G. Hänsch, K. Rother","doi":"10.1016/S0340-904X(76)80028-0","DOIUrl":"10.1016/S0340-904X(76)80028-0","url":null,"abstract":"<div><p>Deviated lysis (d. l.) activity, i. e. lysis of unsensitized cells by lytic C activity, was generated via the classical pathway of C activation (ag ab complexes) and via the alternative pathway (inulin). The activity was observed on the surface of the activating particles and in the fluid phase. The activity was relatively stable at 32°C. Its generation involved the C components C6 through C9 and possibly also C5.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 5","pages":"Pages 442-454"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(76)80028-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82294031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}