Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie最新文献_第2页

Experimental Pulpal Immunization 实验性牙髓免疫

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80072-8

C. Steffen , K. Keresztesi, A.T. Endler, J. Smolen, J. Menzel

{"title":"Experimental Pulpal Immunization","authors":"C. Steffen , K. Keresztesi, A.T. Endler, J. Smolen, J. Menzel","doi":"10.1016/S0300-872X(76)80072-8","DOIUrl":"10.1016/S0300-872X(76)80072-8","url":null,"abstract":"<div><p>The experimental exposure of the pulpal room of rabbit teeth made it possible to apply an ovalbumin agar gel deposit into the pulpal room and subsequently investigate the immune response. Diffusion of antigen from the agar into environment was proven. After 3 weekly applications 5 rabbits showed hemagglutinatiog anti-ovalbumin titers between 1: 128 and 1: 512, while 7 rabbits receiving 10 weekly applications had titers between 1: 8000 and 1: 128,000. Control rabbits which received the agar deposit alone showed no antibody response. Control rabbits which obtained 3 identical weekly doses of ovalbumin in PBS by subcutaneous injection showed an identical immune response as animals immunized via the pulpal room. Specificity of antibodies was ascertained by passive hemagglutination with control antigens and hemagglutination inhibition. Intradermal injection of ovalbumin in 3 rabbits which obtained pulpal immunization, induced an Arthus reaction. The precipitating property of ovalbumin antibodies and their identity with defined ovalbumin antisera was proven by gel diffusion. The results obtained show, that antigens present in the pulpal room provide a strong immunogenic stimulus.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"152 1","pages":"Pages 42-55"},"PeriodicalIF":0.0,"publicationDate":"1976-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-872X(76)80072-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85386975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Effects of Maternal Immunization on the Survival and Postnatal Development of the Offspring 母体免疫对子代生存和产后发育的影响

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80073-X

Thomas J. Gill III , Heinz W. Kunz

引用次数: 0

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80081-9

K.P. Schaal

引用次数: 0

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80079-0

H.W. Baenkler

引用次数: 1

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80077-7

B. Wiedemann

引用次数: 1

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80082-0

K. Federlin

引用次数: 0

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-09-01 DOI: 10.1016/S0300-872X(76)80074-1

F. Scheiffarth

引用次数: 0

Authors’ index 作者的指数

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-08-01 DOI: 10.1016/S0340-904X(76)80037-1

引用次数: 0

Antigenic Relationship between Chicken Brain and Granulocytes 鸡脑与粒细胞的抗原关系

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-08-01 DOI: 10.1016/S0340-904X(76)80025-5

K. Schauenstein, G. Wick

引用次数: 1

The in vitro Effect of Diethylaminoethyl Dextran on Stimulation of Mouse Lymphocytes, and on the Mitogenic Activity of Concanavalin A and Lipopolysaccharide 二乙胺乙基右旋糖酐对小鼠淋巴细胞的体外刺激及对刀豆蛋白A和脂多糖有丝分裂活性的影响

Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie Pub Date : 1976-08-01 DOI: 10.1016/S0340-904X(76)80024-3

Gerhard Bartenbach, Günther Wittmann

{"title":"The in vitro Effect of Diethylaminoethyl Dextran on Stimulation of Mouse Lymphocytes, and on the Mitogenic Activity of Concanavalin A and Lipopolysaccharide","authors":"Gerhard Bartenbach, Günther Wittmann","doi":"10.1016/S0340-904X(76)80024-3","DOIUrl":"10.1016/S0340-904X(76)80024-3","url":null,"abstract":"<div><p>Unpurified lymphocytes from spleen, lymph nodes, thymus, and T and B cellenriched fractions of spleen cells from NMRI mice as well as lymphocytes of nude mice were cultured and stimulation of the lymphocytes by DEAF-D, Con A and LPS and combinations thereof was measured by incorporation of <sub>3</sub>H-thymidine.</p><p>It was demonstrated that DEAE-D is a rather weak mitogen for mouse lymphocytes, acting apparently on B cells as well as on T cells. Frequency and intensity of lymphocyte stimulation by the T cell mitogen Con A and the B cell mitogen LPS was much better.</p><p>When combinations of DEAE-D with Con A or LPS, respectively, were used significant enhancement of lymphocyte stimulation occurred, as compared to the mitogns and DEAE-D alone. This enhancement was more prominent with the DEAE-D/Con A combination than with the DEAE-D/LPS combination, and more pronounced with the T cell-rich lymphocyte preparations than with the B cell-rich suspensions.</p><p>The results are discussed and it is concluded that DEAE-D enhances both T cell and B cell functions, however, T cell functions are favoured. This enhancement is assumed to be mediated by a membrane effect of DEAE-D, and to be responsible for the immunological adjuvant effect of DEAE-D.</p></div>","PeriodicalId":101289,"journal":{"name":"Zeitschrift für Immunitaetsforschung, Experimentelle und Klinische Immunologie","volume":"151 5","pages":"Pages 391-404"},"PeriodicalIF":0.0,"publicationDate":"1976-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0340-904X(76)80024-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88098761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3