Science in One Health最新文献

{"title":"Natural toxins and One Health: a review","authors":"Azubuike Raphael Nwaji ,&nbsp;Onikisateinba Arieri ,&nbsp;Annabel Sharon Anyang ,&nbsp;Kaze Nguedia ,&nbsp;Etomi Barbara Abiade ,&nbsp;Gilead Ebiegberi Forcados ,&nbsp;Olusola Olalekan Oladipo ,&nbsp;Sunday Makama ,&nbsp;Ishaku Leo Elisha ,&nbsp;Nonyelim Ozele ,&nbsp;Jurbe Gofwan Gotep","doi":"10.1016/j.soh.2023.100013","DOIUrl":"10.1016/j.soh.2023.100013","url":null,"abstract":"<div><h3>Background</h3><p>The One Health concept considers the interconnectivity, interactions and interdependence of humans, animals and the environment. Humans, animals and other organisms are constantly exposed to a wide range of natural toxins present in the environment. Thus, there is growing concern about the potential detrimental effects that natural toxins could pose to achieve One Health. Interestingly, alkaloids, steroids and bioactive peptides obtained from natural toxins could be used for the development of therapeutic agents.</p></div><div><h3>Methodology</h3><p>Our literature search focused on the following keywords; toxins, One Health, microbial toxins, mycotoxins, phytotoxins, phycotoxins, insect toxins and toxin effects. Google Scholar, Science Direct, PubMed and Web of Science were the search engines used to obtain primary databases. We chose relevant full-text articles and review papers published in English language only. The research was done between July 2022 and January 2023.</p></div><div><h3>Results</h3><p>Natural toxins are poisonous substances comprising bioactive compounds produced by microorganisms, invertebrates, plants and animals. These compounds possess diverse structures and differ in biological function and toxicity, posing risks to human and animal health through the contamination of the environment, causing disease or death in certain cases. Findings from the articles reviewed revealed that effects of natural toxins on animals and humans gained more attention than the impact of natural toxins on the environment and lower organisms, irrespective of the significant roles that lower organisms play to maintain ecosystem balance. Also, systematic approaches for toxin control in the environment and utilization for beneficial purposes are inadequate in many regions. Remarkably, bioactive compounds present in natural toxins have potential for the development of therapeutic agents. These findings suggest that global, comprehensive and coordinated efforts are required for improved management of natural toxins through an interdisciplinary, One Health approach.</p></div><div><h3>Conclusion</h3><p>Adopting a One Health approach is critical to addressing the effects of natural toxins on the health of humans, animals and the environment.</p></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"1 ","pages":"Article 100013"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949704323000070/pdfft?md5=d995738114bccf425ad9034d75c786d6&pid=1-s2.0-S2949704323000070-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83061929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Health training needs for Senegalese professionals to manage emerging public health threats","authors":"Walter Ossebi ,&nbsp;Andrée Prisca Ndjoug Ndour ,&nbsp;Sara Danièle Dieng ,&nbsp;André Pouwedeou Bedekelabou ,&nbsp;Miguiri Kalandi ,&nbsp;Fatimata Niang Diop ,&nbsp;Rianatou Bada Alambedji ,&nbsp;Yalacé Yamba Kaboret ,&nbsp;Adama Faye ,&nbsp;Bienvenu Sambou","doi":"10.1016/j.soh.2022.100005","DOIUrl":"10.1016/j.soh.2022.100005","url":null,"abstract":"<div><p>Global health trends, marked by increasing epidemics and pandemics, call for enhanced human resource preparedness to prevent and respond to emerging and future health problems. Indeed, according to the World Organization for Animal Health (WOAH), at least 75% of the pathogens responsible for emerging and re-emerging human infectious diseases originate from animals. These health problems involve environmental, economic and social factors. Because of their multidimensional nature, addressing these health problems requires the adoption of a One Health approach. To achieve this, training of human resources is a priority.</p><p>This descriptive cross-sectional study was conducted from September 12 to 22, 2021 in 6 regions of Senegal, namely, Dakar, Thiès, Diourbel, Kaolack, Saint-Louis, and Ziguinchor. Questionnaires were administered online and in person to 217 professionals in human, environmental, animal health and agriculture. Data were statistically processed, and bivariate analyses enabled a better correlation between training needs for professionals according to their occupational group.</p><p>The survey sample was 64% male and 36% female. More than half of the professionals surveyed (53.5%) had less than 10 years of experience. Human health workers were the most represented (46%), followed by animal health workers (34%) and environmental workers (16%). Agriculture, fisheries, and food security were weakly represented. Few had received training in the One Health approach and entry-level One Health skills predominated. The One Health competencies in which professionals want to build capacity differ by sector. Globally, public health and epidemiology, health risk management, basic of One Health concepts, animal health and biotechnology are the priorities.</p><p>The development of training programs could then enable these expressed needs to be addressed.</p></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"1 ","pages":"Article 100005"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949704322000051/pdfft?md5=acb13df452cc1ecdc51224d7e8a1cd8c&pid=1-s2.0-S2949704322000051-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89205669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Health approaches adapted in low resource settings to address antimicrobial resistance","authors":"Ripan Biswas ,&nbsp;Chanchal Debnath ,&nbsp;Samiran Bandyopadhyay ,&nbsp;Indranil Samanta","doi":"10.1016/j.soh.2023.100011","DOIUrl":"10.1016/j.soh.2023.100011","url":null,"abstract":"<div><p>Inter-disciplinary collaborations are now considered as key factors for integrated health system strengthening. Its application in the domain of One Health needs more milestones to achieve. Other than the human health sector, the antimicrobials are used in food animals and aquaculture for therapy, prophylaxis and growth promotion which significantly contributes to the development of antimicrobial resistance. It is the high time to develop a sustainable collaboration between the concerned sectors of One Health for a resilient health system. The domain of One Health not only mitigates the emergence of antimicrobial resistance but also helps in realizing the surveillance and epidemiology of zoonotic diseases, and the control of public health emergencies such as COVID-19. The review identified the key One Health strategies adapted by India, the exemplary low resource settings, to address antimicrobial resistance and zoonosis.</p></div>","PeriodicalId":101146,"journal":{"name":"Science in One Health","volume":"1 ","pages":"Article 100011"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949704323000057/pdfft?md5=8d6bea012119517ac9f509e127c6a9de&pid=1-s2.0-S2949704323000057-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90337270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}