中国现代神经疾病杂志最新文献

{"title":"Rehabilitation treatment in acute stage of stroke","authors":"Jia-Ling Wu","doi":"10.3969/CJCNN.V17I4.1572","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1572","url":null,"abstract":"","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"241-244"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43190686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of low-frequency repetitive transcranial magnetic stimulation combining task-oriented training on upper limb motor function recovery after stroke","authors":"Hongbin Wang, Hua Long, Hua Yuan, Qiang Duan, Nan Hui, Hong Wang, Li Mao, Xiang Mou","doi":"10.3969/CJCNN.V17I4.1575","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1575","url":null,"abstract":"Objective To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with task-oriented training on the recovery of upper limb motor function of stroke patients. Methods A total of 42 patients with hemiplegia after stroke were randomly divided into control group (N = 20) and treatment group (N = 22). Control group received routine rehabilitation training and task-oriented training, and treatment group received low-frequency (1 Hz) rTMS over the contralesional cortex addition to routine rehabilitation and task-oriented training. Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) were used to evaluate upper limb motor function of all patients before treatment, after 4-week treatment and 3 months after treatment. The latency and central motor conduction time (CMCT) of motor-evoked potential (MEP) in the contralesional cortex were recorded and analyzed. Results Compared with control group, FMA-UE score ( P = 0.006) and WMFT score ( P = 0.024) were significantly increased in treatment group. There was significant difference in FMA-AUE score ( P = 0.000) and WMFT score ( P = 0.000) at different time points. Compared with before treatment, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) of patients in both groups were all significantly increased after 4-week treatment and 3 months after treatment. Besides, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) 3 months after treatment were higher than those after 4-week treatment. There was no statistically significant difference between 2 groups on the latency ( P = 0.979) and CMCT ( P = 0.807) of MEP before and after treatment, and so was the difference on the latency ( P = 0.085) and CMCT ( P = 0.507) of MEP in the contralesional cortex at different time points (before treatment, after 4-week treatment and 3 months after treatment). Conclusions Low-frequency rTMS over the contralesional cortex combined with task-oriented training could greatly promote upper limb motor function of patients after stroke, and should be recommended to clinical application. DOI: 10.3969/j.issn.1672-6731.2017.04.004","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"254-260"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45314602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in clinical research of post-stroke depression","authors":"Chunli Gao, Jia-Ling Wu","doi":"10.3969/CJCNN.V17I4.1574","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1574","url":null,"abstract":"Post-stroke depression (PSD) is a serious complication affecting the survival and functional recovery of stroke patients. The prevalence rate of PSD is about 30% . PSD happens mostly within one year after stroke, and especially within 3 months after stroke. The main risk factors of PSD were disability, past history of depression, stroke severity, cognitive dysfunction and anxiety symptoms. The treatment principles of PSD include drug treatment, psychological therapy, rehabilitation therapy, physical therapy and others. Especially, rehabilitation therapy can significantly reduce the incidence of PSD and improve the prognosis. Further study on the mechanism of PSD and optimization of PSD rehabilitation therapy can improve PSD prognosis. DOI: 10.3969/j.issn.1672-6731.2017.04.003","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"12 S1","pages":"249-253"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41266009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain and numbness of left upper limb for five months, weakness for three months, aggravating with pain and weakness of other limbs for one month","authors":"J. Niu, H. Guan, Ying-mai Yang, Mingsheng Liu, B. Peng, L. Cui","doi":"10.3969/CJCNN.V17I4.1584","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1584","url":null,"abstract":"患者 女性,50 岁,主因左上肢疼痛、麻木 5 个月,无力 3 个月,加重伴双下肢和右上肢相继疼痛、无力 1 个月,于 2015 年 7 月 23 日入院。患者 5 个月前无明显诱因出现左上 臂外侧持续性刀割样疼痛,可以忍受,伴左前臂外侧及左手 拇指、食指和中指麻木,否认肢体无力,自行服用“止痛片”后 疼痛缓解,但左上肢疼痛进行性加重,外院行颈椎 MRI 检查 显示,C3-4椎间盘轻度突出,C4-5椎间盘膨出,硬脊膜囊轻度受 压,予镇痛药和中药(具体方案不详)治疗后症状无明显好 转,并出现左手无名指和小指麻木。3 个月前出现左上肢无 力,进行性加重,约 1 周左上臂抬举不能、左手持物不能,并 出现右侧臀部、右大腿后侧、右小腿外侧放射性疼痛,伴右侧 足底麻木、右下肢轻微无力,外院行腰椎 MRI 检查显示,L4-5 和 L5-S1椎间盘膨出,椎管囊肿。遂至外院住院治疗,腰椎穿 刺脑脊液检查蛋白定量 350 mg/L(150 ~ 400 mg/L),血清抗神 经节苷脂 GM1 抗体和莱姆抗体阴性。肌电图显示,右侧胫 前肌神经源性损伤;神经传导速度(NCV)显示,左侧正中神 经运动和感觉传导波幅降低,右侧腓总神经运动波幅降低。 胸椎 MRI 显示,T3 ~ 6水平脊髓纤细。临床诊断“臂丛神经炎”, 予甲泼尼龙静脉滴注 1000 mg/d 连续 3 d 后减至 500 mg/d,连 续 3 d 后减至 240 mg/d,连续 3 d,左上肢疼痛缓解[视觉模拟 评分(VAS)为 3 ~ 4 分],麻木、无力症状有所好转,左上肢可 抬举。出院后继续予泼尼松 50 mg/d 口服,缓慢减量。1 个 月前出现双侧小腿和大腿内侧疼痛并进行性加重(VAS 评分 为 10 分),伴双下肢无力,尤以右下肢显著;20 d 前症状明显 加重,3 d 后无法独立行走,伴双侧大腿肉跳感,并出现左侧 额纹消失、左眼闭目不能、左侧鼻唇沟变浅、口角向右侧歪 斜,否认吞咽困难、饮水呛咳和呼吸困难,再次至外院住院治 疗。复查腰椎穿刺脑脊液常规和生化均于正常值范围,血清 和脑脊液莱姆抗体,抗 Hu、Yo、Ri 抗体,抗神经节苷脂 GM1 抗体均阴性。PET⁃CT 显示,C4-5 和 C5-6 椎间孔左侧片状代谢 增高[标准化摄取值(SUV)5.90],右侧颈后软组织片状代谢 增高(SUV 3.60)。临床诊断“免疫介导性周围神经病变可能 性大,不排除副肿瘤性周围神经病”,予甲泼尼龙 500 mg/d 静 脉滴注,连续 5 d 后减至 240 mg/d,连续 3 d 后减至 120 mg/d, 连续 2 d 后改为甲泼尼龙 40 mg/d 口服,维持治疗。激素冲击 治疗后疼痛有所缓解(VAS 评分为 4 ~ 5 分),但无力症状无明 显好转,并出现右上肢疼痛、麻木、无力,伴肉跳感。为求进 一步诊断与治疗,遂至我院就诊。患者服用激素以来,口干、 肢体疼痛时伴关节疼痛,不伴红、肿、热,无发热、皮疹、脱发、 光过敏、眼干、口腔溃疡、雷诺现象,精神尚可,夜间因疼痛睡 眠质量较差,进食量减至正常 1/2,小便正常,近 1 个月便秘, 每 3 天排便 1 次,自述排便无力感,近 6 个月体重下降 5 kg。 既往史、个人史及家族史 患者子宫肌瘤病史 30 年,未 予手术治疗;1 年前曾出现左侧面瘫,予针灸治疗后痊愈。 否认森林旅游史,疫区、疫水接触史,否认特殊化学物品和毒 物接触史。个人史、婚育史和月经史无特殊。其兄患结肠 癌,家族中无类似疾病病史。 入院后体格检查 患者体温 36.3 °C,呼吸 18 次/min,脉 左上肢疼痛麻木 5 个月 无力 3 个月 加重伴双下肢和右上肢相继疼痛 无力 1 个月","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"311-314"},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46101023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of early trunk control training on balance function of patients with acute stroke","authors":"Bao-jin Li, Cheng Li, Jing Li, Q. Gao","doi":"10.3969/CJCNN.V17I4.1576","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1576","url":null,"abstract":"Background Trunk is the core part of human body, and plays an important role in maintaining the body balance. Studies show that trunk control training can improve the balance function and mobility ability, and promote motor function and activities of daily living (ADL) of stroke patients. This study aims to investigate the effect of early trunk control training on the recovery of balance function of acute stroke patients.  Methods A total of 120 patients with acute ischemic stroke (duration ≤ 14 d) were randomly divided into 2 groups: control group [N = 60, 39 males and 21 females; age 23-85 years, mean age (63.43 ± 13.61) years; duration 1-13 d, median duration 4.12 (2.30, 6.09) d] and observation group [N = 60, 40 males and 20 females; age 20-84 years, average age (62.55 ± 13.77) years; duration 1-12 d, median duration 4.19 (2.48, 6.30) d]. Control group was given routine drug treatment plus rehabilitation education and guidance, and observation group was given routine drug treatment, rehabilitation education and guidance plus trunk control training. Fugl-Meyer Assessment Scale-Balance (FMA-Balance) and Modified Rivermead Mobility Index (MRMI) were used to evaluate the balance function of patients in both groups before training and after 2-week training.  Results All patients finished the rehabilitation training programme without adverse reactions. Compared with before training, the scores of FMA-Balance ( P =0.000) and MRMI ( P = 0.000) were significantly increased after 2-week training in both groups. Compared to control group, the scores of FMA-Balance ( P = 0.002) and MRMI ( P = 0.002) were significantly increased after 2-week training in observation group.  Conclusions Early trunk control training can significantly improve the balance function and motor ability of patients with acute stroke. DOI: 10.3969/j.issn.1672-6731.2017.04.005","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"261-265"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43211133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application progress of virtual reality rehabilitation technology in upper limb dysfunction after stroke","authors":"Bing Li, Fang Li","doi":"10.3969/CJCNN.V17I4.1573","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I4.1573","url":null,"abstract":"Virtual reality (VR) rehabilitation technology is a kind of integrated technology which simulates the real world via computer. It has three characteristics: immersion, interaction and imagination. It is widely used in the field of stroke rehabilitation. This review briefly describes the application of virtual reality rehabilitation technology in upper limb dysfunction after stroke. DOI: 10.3969/j.issn.1672-6731.2017.04.002","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"245-248"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49570292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of new technologies in stroke rehabilitation","authors":"Lin Meng, Dan Huang, Hong-hong Liu, Yun Qu","doi":"10.3969/CJCNN.V17I3.1559","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1559","url":null,"abstract":"Survivors of stroke commonly experience a different range of dysfunction, and recovery can be slow and incomplete, which lead to a serious and long-term impact on patients themselves and their families. Although the treatment of stroke patients relies mainly on rehabilitation intervention, but the rehabilitation needs of discharged patients are not fully met due to lots of restrictions, such as the lack of professional rehabilitation services, the difficulty and inconvenience in transportation from home to hospital, therefore their prognosis of rehabilitation are affected. At present a number of new rehabilitation technologies, including telerehabilitation (TR), virtual reality (VR), robotics, electronic textiles (E-textiles), etc., are coming into being and may solve these problems. This article tries to discuss the research progress of these new rehabilitation technologies, and provide a new perspective for the rehabilitation intervention of stroke patients. DOI: 10.3969/j.issn.1672-6731.2017.03.003","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"171-175"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44676594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic dissection with weakness of lower limb as initial symptom: one case report","authors":"Bai-yuan Yang, Wei Zhong, Shuai Li, Xinglong Yang","doi":"10.3969/CJCNN.V17I3.1570","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1570","url":null,"abstract":"","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"232-234"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42898678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of antiplatelet therapy for treating lacunar infarct: Meta-analysis","authors":"Da Xu, Deng Chen, Lina Zhu, G. Tan, Haijiao Wang, Ling Liu","doi":"10.3969/CJCNN.V17I3.1560","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1560","url":null,"abstract":"Objective To evaluate the efficacy of antiplatelet agents in secondary prevention of patients with lacunar infarct (LACI). Methods Retrieve relevant randomized controlled trials (RCTs) that reported antiplatelet therapy in patients with LACI from online databases (January 1, 1980-November 20, 2016) in PubMed, EMBASE/SCOPUS and Cochrane Online Library with key words: stroke, lacunar infarction, platelet aggregation inhibitors, antiplatelet, randomized controlled trial. Quality of studies was evaluated by using Jadad Scale and Cochrane Handbook for Systematic Reviews of Interventions. All data were pooled by RevMan 5.3 software for Meta-analysis. A network Meta-analysis was done by R software Gemtc and JAGS software. Results A total of 4068 articles were enrolled and 12 high - quality RCTs (Jadad ≥ 4 scores) with 24 969 eligible participants were finally included after excluding duplicates and those not meeting the inclusion criteria. Meta-analysis showed single antiplatelet therapy was more effective than placebo in reducing ischemic stroke recurrence rate ( RR = 0.480, 95%CI: 0.300-0.780; P = 0.003) and any stroke recurrence rate ( RR = 0.780, 95%CI: 0.630-0.970; P = 0.030). The efficacy of single antiplatelet therapy was not significantly different from that of dual antiplatelet therapy (ischemic stroke recurrence rate: RR = 0.900, 95%CI: 0.760-1.050, P = 0.170; any stroke recurrence rate: RR = 0.910, 95%CI: 0.820-1.010, P = 0.070). Network Meta-analysis (four interventions including aspirin, placebo, cilostazol and ticlopidine) showed that cilostazol was associated with a significant reduction in recurrence of any stroke compared with aspirin ( OR = 0.341, 95% CrI: 0.011-0.673) and placebo ( OR = 0.615, 95% CrI: 0.191-1.042). Conclusions Single antiplatelet therapy could significantly reduce the recurrence of any stroke, especially ischemic stroke in patients with LACI. There is no evidence showing that dual antiplatelet therapy is probably better than single therapy. Cilostazol is better than aspirin in reducing any stroke recurrence in the treatment of LACI. DOI: 10.3969/j.issn.1672-6731.2017.03.004","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"176-184"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43503099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision rehabilitation in stroke","authors":"Yi Wu","doi":"10.3969/CJCNN.V17I3.1557","DOIUrl":"https://doi.org/10.3969/CJCNN.V17I3.1557","url":null,"abstract":"","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"161-165"},"PeriodicalIF":0.0,"publicationDate":"2017-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49052288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}