Hongbin Wang, Hua Long, Hua Yuan, Qiang Duan, Nan Hui, Hong Wang, Li Mao, Xiang Mou
{"title":"低频重复经颅磁刺激结合任务导向训练对脑卒中后上肢运动功能恢复的影响","authors":"Hongbin Wang, Hua Long, Hua Yuan, Qiang Duan, Nan Hui, Hong Wang, Li Mao, Xiang Mou","doi":"10.3969/CJCNN.V17I4.1575","DOIUrl":null,"url":null,"abstract":"Objective To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with task-oriented training on the recovery of upper limb motor function of stroke patients. Methods A total of 42 patients with hemiplegia after stroke were randomly divided into control group (N = 20) and treatment group (N = 22). Control group received routine rehabilitation training and task-oriented training, and treatment group received low-frequency (1 Hz) rTMS over the contralesional cortex addition to routine rehabilitation and task-oriented training. Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) were used to evaluate upper limb motor function of all patients before treatment, after 4-week treatment and 3 months after treatment. The latency and central motor conduction time (CMCT) of motor-evoked potential (MEP) in the contralesional cortex were recorded and analyzed. Results Compared with control group, FMA-UE score ( P = 0.006) and WMFT score ( P = 0.024) were significantly increased in treatment group. There was significant difference in FMA-AUE score ( P = 0.000) and WMFT score ( P = 0.000) at different time points. Compared with before treatment, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) of patients in both groups were all significantly increased after 4-week treatment and 3 months after treatment. Besides, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) 3 months after treatment were higher than those after 4-week treatment. There was no statistically significant difference between 2 groups on the latency ( P = 0.979) and CMCT ( P = 0.807) of MEP before and after treatment, and so was the difference on the latency ( P = 0.085) and CMCT ( P = 0.507) of MEP in the contralesional cortex at different time points (before treatment, after 4-week treatment and 3 months after treatment). Conclusions Low-frequency rTMS over the contralesional cortex combined with task-oriented training could greatly promote upper limb motor function of patients after stroke, and should be recommended to clinical application. DOI: 10.3969/j.issn.1672-6731.2017.04.004","PeriodicalId":10113,"journal":{"name":"中国现代神经疾病杂志","volume":"17 1","pages":"254-260"},"PeriodicalIF":0.0000,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Effect of low-frequency repetitive transcranial magnetic stimulation combining task-oriented training on upper limb motor function recovery after stroke\",\"authors\":\"Hongbin Wang, Hua Long, Hua Yuan, Qiang Duan, Nan Hui, Hong Wang, Li Mao, Xiang Mou\",\"doi\":\"10.3969/CJCNN.V17I4.1575\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with task-oriented training on the recovery of upper limb motor function of stroke patients. Methods A total of 42 patients with hemiplegia after stroke were randomly divided into control group (N = 20) and treatment group (N = 22). Control group received routine rehabilitation training and task-oriented training, and treatment group received low-frequency (1 Hz) rTMS over the contralesional cortex addition to routine rehabilitation and task-oriented training. Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) were used to evaluate upper limb motor function of all patients before treatment, after 4-week treatment and 3 months after treatment. The latency and central motor conduction time (CMCT) of motor-evoked potential (MEP) in the contralesional cortex were recorded and analyzed. Results Compared with control group, FMA-UE score ( P = 0.006) and WMFT score ( P = 0.024) were significantly increased in treatment group. There was significant difference in FMA-AUE score ( P = 0.000) and WMFT score ( P = 0.000) at different time points. Compared with before treatment, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) of patients in both groups were all significantly increased after 4-week treatment and 3 months after treatment. Besides, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) 3 months after treatment were higher than those after 4-week treatment. There was no statistically significant difference between 2 groups on the latency ( P = 0.979) and CMCT ( P = 0.807) of MEP before and after treatment, and so was the difference on the latency ( P = 0.085) and CMCT ( P = 0.507) of MEP in the contralesional cortex at different time points (before treatment, after 4-week treatment and 3 months after treatment). Conclusions Low-frequency rTMS over the contralesional cortex combined with task-oriented training could greatly promote upper limb motor function of patients after stroke, and should be recommended to clinical application. 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Effect of low-frequency repetitive transcranial magnetic stimulation combining task-oriented training on upper limb motor function recovery after stroke
Objective To investigate the effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) combined with task-oriented training on the recovery of upper limb motor function of stroke patients. Methods A total of 42 patients with hemiplegia after stroke were randomly divided into control group (N = 20) and treatment group (N = 22). Control group received routine rehabilitation training and task-oriented training, and treatment group received low-frequency (1 Hz) rTMS over the contralesional cortex addition to routine rehabilitation and task-oriented training. Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE) and Wolf Motor Function Test (WMFT) were used to evaluate upper limb motor function of all patients before treatment, after 4-week treatment and 3 months after treatment. The latency and central motor conduction time (CMCT) of motor-evoked potential (MEP) in the contralesional cortex were recorded and analyzed. Results Compared with control group, FMA-UE score ( P = 0.006) and WMFT score ( P = 0.024) were significantly increased in treatment group. There was significant difference in FMA-AUE score ( P = 0.000) and WMFT score ( P = 0.000) at different time points. Compared with before treatment, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) of patients in both groups were all significantly increased after 4-week treatment and 3 months after treatment. Besides, FMA-UE score ( P = 0.000, for all) and WMFT score ( P = 0.000, for all) 3 months after treatment were higher than those after 4-week treatment. There was no statistically significant difference between 2 groups on the latency ( P = 0.979) and CMCT ( P = 0.807) of MEP before and after treatment, and so was the difference on the latency ( P = 0.085) and CMCT ( P = 0.507) of MEP in the contralesional cortex at different time points (before treatment, after 4-week treatment and 3 months after treatment). Conclusions Low-frequency rTMS over the contralesional cortex combined with task-oriented training could greatly promote upper limb motor function of patients after stroke, and should be recommended to clinical application. DOI: 10.3969/j.issn.1672-6731.2017.04.004
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